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INTRODUCTION ABOUT AKROZ 5MG TABLET
AKROZ 5MG TABLET is used in the management of high blood cholesterol levels. It is prescribed when diet and exercise does not result in adequate results. It contains a medicine called Rosuvastatin which is an anti-hyperlipidemic agent that works by blocking cholesterol production in the body. It also makes your body eliminate lipids particles from the blood.
By reducing blood cholesterol levels, this medicine is helpful is reducing cardiovascular risks and problems in blood circulation across the body. While taking AKROZ 5MG TABLET, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor to achieve better results.
Before taking AKROZ 5MG TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, thyroid problems, or a family history of muscle disorders. Do not take AKROZ 5MG TABLET if you are pregnant or breastfeeding without consulting your doctor.
AKROZ 5MG TABLET may increase your blood sugar levels, especially in patients who are diabetic. It may also affect the way your liver works and so your doctor will closely monitor your blood sugar levels and liver functions while undergoing therapy with AKROZ 5MG TABLET as a precaution.
The most common side effects of taking AKROZ 5MG TABLET are muscle ache, constipation, stomach pain, dizziness, nausea and headache. Inform your doctor if you experience severe unexplained muscle pain, tenderness or weakness along with fever after taking AKROZ 5MG TABLET.
USES OF AKROZ 5MG TABLET
It is used to:
- manage high blood cholesterol levels
- manage the risk of heart attack or stroke
HOW AKROZ 5MG TABLET WORKS
AKROZ 5MG TABLET is a lipid lowering medicine. It effectively reduces the levels of bad cholesterol (LDL) and triglycerides in the body by blocking the action of an enzyme called HMG-CoA reductase that synthesizes cholesterol within the body. It also acts on the liver and improve the body’s ability to remove lipid particles from the blood. As a result, it reduces blood cholesterol levels and manage its associated risks.
DIRECTIONS FOR USE
- Take AKROZ 5MG TABLET as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- AKROZ 5MG TABLET can be taken with or without meals
SIDE EFFECTS OF AKROZ 5MG TABLET
Common side effects of AKROZ 5MG TABLET:
- headache
- dizziness
- stomach pain
- constipation
- nausea
- muscle pain
- tiredness
- diabetes
- protein loss in urine
- itching, rash or other skin reactions
Stop taking AKROZ 5MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- unexplained muscle pain or weakness, especially if accompanied by fever, weakness, or reddish-brown urine
- severe skin rash with joint disorders and changes in blood counts (lupus-like disease syndrome)
- liver problems which may lead to yellowing of the skin and eyes (jaundice)
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedAKROZ 5MG TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it. Women of childbearing age must use a reliable contraceptive method to avoid pregnancy while undergoing therapy. However, if you accidentally become pregnant while taking this medicine, stop taking it and consult your doctor immediately.
BREASTFEEDING
ContraindicatedAKROZ 5MG TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking AKROZ 5MG TABLET.
ALCOHOL
Consult your doctorAKROZ 5MG TABLET should be used with caution in patients who consume large amounts of alcohol. Therefore, it is advisable to avoid alcohol consumption while taking this medicine to achieve maximum benefits.
KIDNEY
Consult your doctorAKROZ 5MG TABLET is not recommended for use in patients with moderate to severe kidney diseases. It should be used with caution in patients with other mild kidney problems. Therefore, consult your doctor before taking it.
LIVER
Consult your doctorAKROZ 5MG TABLET is not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.
ALLERGY
ContraindicatedDo not take AKROZ 5MG TABLET if you are allergic to Rosuvastatin or any other ingredients of this medicine.
LUNGS
Use with CautionAKROZ 5MG TABLET should be used with caution in patients with lung diseases (such as severe respiratory failure). Therefore, consult your doctor before taking it.
HEART DISEASE
Use with CautionAKROZ 5MG TABLET should be used with caution in patients with high blood pressure. Therefore, consult your doctor before taking it.
USE IN PEDIATRICS
Consult your doctorAKROZ 5MG TABLET is not recommended for use in children aged below 6 years. It should be used in children and adolescents (aged above 6 years) only if prescribed by the physician. Your doctor will decide the correct dose depending on your child’s age, body weight and health condition. However, higher doses of rosuvastatin (40 mg or above) are generally restricted for use in children and adolescents (aged below 18 years).
USE IN GERIATRICS
Use with CautionAKROZ 5MG TABLET should be used with caution in elderly patients (aged 70 years or older). Therefore, consult your doctor for advice before taking it.
OTHERS
AKROZ 5MG TABLET is not recommended for use if you:
- have an unexplained muscle pain
- have improper functioning of thyroid gland
Before taking AKROZ 5MG TABLET, inform your doctor if you:
- have problems in thyroid gland
- have personal or family history of muscle problems
- are alcoholic
- have diabetes
- are overweight
INTERACTIONS
A. Drug-Drug Interactions:
Before taking AKROZ 5MG TABLET, inform your doctor if you are taking any of the following medicines such as:
- Immunosuppressants (Ex. Cyclosporin)
- Fibrates (Ex. Gemfibrozil, fenofibrate, ezetimibe)
- Antibiotics (Ex. Fusidic acid, Erythromycin)
- Blood thinners (Ex. Warfarin, Ticagrelor or Clopidogrel)
- Oral contraceptives (Ex. Levonorgestrel)
- Kinase inhibitors. (Ex. Regorafenib, Darolutamide)
- Hormone replacement therapy (Ex. Dydrogesterone, Estradiol)
- Anti-viral agents (Ex. Ritonavir, lopinavir, atazanavir, sofosbuvir, voxilaprevir, simeprevir, ombitasvir, elbasvir, glecaprevir, pibrentasvir, paritaprevir, dasabuvir, velates, grazoprevir)
- H2 blockers (Ex. Cimetidine)
- Antacids (Ex. Aluminium hydroxide or magnesium hydroxide)
Overdosage:
If you or anyone else accidentally took more AKROZ 5MG TABLET, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Rosuvastatin |
| Pharmacological Category | : | HMG-CoA reductase inhibitors |
| Therapeutic Indication | : | Hyperlipidaemia |
| Dosage Forms | : | Tablet |
MORE INFORMATION
FAQs ABOUT AKROZ 5MG TABLET
Q: What is AKROZ 5MG TABLET used for?
A: AKROZ 5MG TABLET is used to lower high cholesterol and triglyceride levels in the blood. It belongs to the statin class of drugs that reduce the production of cholesterol in the liver. It is commonly prescribed for managing high LDL (bad cholesterol), increasing HDL (good cholesterol) and reducing triglycerides. By doing so, this medicine helps in reducing the risk of cardiovascular diseases, like heart attack and stroke, in individuals with high cholesterol or other risk factors like diabetes or hypertension.
Q: Does AKROZ 5MG TABLET reduce BP?
A: No, AKROZ 5MG TABLET is not directly used to lower blood pressure (BP). However, by reducing cholesterol and improving overall heart health, it may indirectly reduce cardiovascular risks, which can benefit people with high BP. If BP reduction is the goal, other medications like ACE inhibitors or beta-blockers are more appropriate.
Q: What are the side effects of AKROZ 5MG TABLET?
A: The most common side effects of this medicine include muscle pain or weakness (myalgia), headache or dizziness, stomach upset, nausea, or constipation, and mild liver enzyme elevation. Consult your doctor if any of these side effect troubles you or if you experience severe muscle pain and weakness, stomach pain or memory issues.
Q: When is the best time to take AKROZ 5MG TABLET?
A: AKROZ 5MG TABLET can be taken at any time of the day, but it is most effective when taken at the same time daily. Some doctors prefer prescribing it in the evening since cholesterol synthesis in the liver is more active at night. Always follow your doctor’s advice on timing.
Q: Is AKROZ 5MG TABLET bad for the liver?
A: AKROZ 5MG TABLET can mildly elevate liver enzymes in some individuals, which is usually temporary. In rare cases, it may cause liver injury. Regular liver function tests are recommended during treatment. If you have a history of liver disease, inform your doctor before starting AKROZ 5MG TABLET.
Q: Can I stop taking rosuvastatin if my cholesterol is normal?
A: You should not stop taking this medicine without consulting your doctor. Stopping the medication can cause your cholesterol levels to rise again, increasing the risk of cardiovascular problems. Long-term treatment may be necessary even if your levels normalize.
Q: Is 5mg of rosuvastatin enough to lower cholesterol?
A: For some individuals, 5 mg may be sufficient to lower cholesterol, especially if their cholesterol levels are only mildly elevated or if they are at a higher risk of side effects. Higher doses (10-40 mg) are typically used for more significant cholesterol reductions. Your doctor will determine the appropriate dose for your condition.
Q: Does AKROZ 5MG TABLET increase blood sugar?
A: Yes, AKROZ 5MG TABLET can increase blood sugar levels slightly, particularly in individuals with diabetes or those predisposed to developing diabetes. However, the cardiovascular benefits of taking the medication usually outweigh this risk. Monitor blood sugar regularly if you have diabetes.
Q: Who cannot take rosuvastatin?
A: Rosuvas should not be taken by pregnant or breastfeeding women (as it can harm the baby), people with active liver disease, individuals with a history of severe allergic reactions to rosuvastatin, those with unexplained persistent muscle pain or weakness, especially if associated with statin use and Children. Therefore, consult your doctor for advice.
Q: What foods cannot be eaten with statins?
Grapefruit and grapefruit juice: They can increase the levels of rosuvastatin in the blood, heightening the risk of side effects.
Alcohol: Excessive alcohol can strain the liver, increasing the risk of liver damage.
High-fat or fried foods: These can counteract the cholesterol-lowering effects of the medication.
A heart-healthy diet with plenty of fruits, vegetables, whole grains, and lean proteins is recommended.
Q: Does AKROZ 5MG TABLET reduce triglycerides?
A: Yes, AKROZ 5MG TABLET effectively reduces triglyceride levels in the blood. While its primary effect is on lowering LDL cholesterol, it also helps lower triglycerides, especially in individuals with mixed dyslipidemia (high cholesterol and triglycerides).
Q: Does AKROZ 5MG TABLET cause sleepiness?
A: Sleepiness or fatigue is not a common side effect of AKROZ 5MG TABLET, but some individuals may experience it. If you feel persistently drowsy, discuss it with your doctor, as other underlying conditions or medications could be contributing to this symptom.
REFERENCES
1. KD. Tripathi. Insulin, Hypolipidemic Drugs and Plasma Expanders. Essentials of medical pharmacology. Seventh edition. 2013. Page-637.
2. Tadateru Takayama, Sei Komatsu, Yasunori Ueda, Seiji Fukushima, Takafumi Hiro, Atsushi Hirayama, Satoshi Saito, ALTAIR study group. Comparison of the Effect of Rosuvastatin 2.5 mg vs 20 mg on Coronary Plaque Determined by Angioscopy and Intravascular Ultrasound in Japanese with Stable Angina Pectoris (from the Aggressive Lipid-Lowering Treatment Approach Using Intensive Rosuvastatin for Vulnerable Coronary Artery Plaque [ALTAIR] Randomized Trial). NIH National Library of Medicine, National Center for biotechnology information. Pubmed.gov. April 2016. [Accessed on September 18, 2024] click here
3. APL Swift Services (Malta) Limited. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on September 18, 2024] click here
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