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INTRODUCTION ABOUT HICOPE 25MG TABLET
HICOPE 25MG TABLET contains Hydroxyzine which belongs to the group of medicines called Antihistamines. It is used to manage allergic reactions (itching, sneezing), for anxiety and tension as well as for sedation (for inducing sleep in medical conditions and after anesthesia).
An allergy is an immune response to foreign elements which is not harmful to the body. These foreign elements are known as allergens. Allergic condition varies from person to person. Some might be allergic to some foods and seasonal allergies like hay fever and while others may be allergic to pollen or pet dander. Anxiety is a sense of uneasiness, dread, and fear. It might cause restlessness, tense, sweat, and have a rapid heartbeat. It may be a usual response to stress.
HICOPE 25MG TABLET is not recommended for use in patients having porphyria, heart problems, and low salt levels in the body. Before taking HICOPE 25MG TABLET, inform your doctor if you have liver, kidney, or mental health problems.
HICOPE 25MG TABLET is not recommended to use among pregnant and breastfeeding women. Your doctor will prescribe the right dose depends on your child’s age, body weight and health condition.
The most common side effects of taking HICOPE 25MG TABLET are feeling sleepy, dry mouth, feeling tired, drowsiness, and headache. Contact your doctor if any of the above side effects worsen or persist for a longer duration.
USES OF HICOPE 25MG TABLET
It is used to manage:
- allergic reactions
- itching due to urticaria (nettle rash) and dermatitis
- anxiety
HOW HICOPE 25MG TABLET WORKS
HICOPE 25MG TABLET works by blocking the action of a chemical messenger (histamine). This relieves allergy indications such as itching, swelling, and rashes. In anxiety, it works by decreasing the activity in the brain, thereby helping to feel relaxed/sleepy.
DIRECTIONS FOR USE
Take HICOPE 25MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
SIDE EFFECTS OF HICOPE 25MG TABLET
COMMON
- dry mouth
- tiredness
- headache
- drowsiness
UNCOMMON
- agitation
- confusion
- dizziness
- sleeplessness
- tremors
- nausea
- fever
RARE
- disorientation, hallucinations (seeing things that are not there)
- movement disorder
- low blood pressure
- constipation
- vomiting
- changes in liver enzyme values
- itching, skin rash with redness, spots or blemishes, skin inflammation
Stop taking HICOPE 25MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- problems with the heart rhythm such as trouble breathing, palpitations, or loss of consciousness
- allergic reaction with difficulty in breathing, fever, or swelling
- severe allergic reaction (Stevens-Johnson syndrome) (symptoms like fever, inflammation, blistering, and ulceration of the skin which can result in the surface layer of the skin peeling away)
- fits (convulsions)
- chest tightening
- blurred vision and have difficulty focusing
- an inability to pass urine
HOW TO MANAGE SIDE EFFECTS
Nausea or Vomiting:
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods.
Headache:
Rest and relax. Drink plenty of fluids such as water. Apply a pain-relieving balm on the head if required. Do not consume alcohol. Consult your doctor if the symptom did not improve.
Dizziness:
If you feel dizzy, keep your eyes closed sit or lie down. Do not drive or operate machinery. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS
PREGNANCY
HICOPE 25MG TABLET is generally not recommended to use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
BREASTFEEDING
HICOPE 25MG TABLET is generally not recommended to use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel drowsy and feel less alert than usual after taking HICOPE 25MG TABLET.
ALCOHOL
Avoid consumption of alcohol while taking HICOPE 25MG TABLET as it may increase the risk of side effects.
KIDNEY
HICOPE 25MG TABLET should be taken with caution in patients with kidney problems and bladder outflow obstruction. Consult your doctor before taking.
LIVER
HICOPE 25MG TABLET should be taken with caution in patients with liver problems. Consult your doctor before taking.
ALLERGY
Do not take HICOPE 25MG TABLET if you are allergic to Hydroxyzine or any other piperazine derivatives, aminophylline, ethylenediamine, or any of the other ingredients of this medicine.
LUNGS
HICOPE 25MG TABLET should be taken with caution in patients with breathing problems. Consult your doctor before taking.
HEART DISEASE
HICOPE 25MG TABLET is not recommended for patients with prolonged QT interval causing irregular heartbeat and/or palpitations or low heart rate. It should be taken with caution in patients with high blood pressure and mild to moderate heart problems. Consult your doctor before taking.
OTHERS
HICOPE 25MG TABLET is not recommended for use if you:
- have asthma
- have porphyria (a disease that causes constipation, changes in the color of urine, stomach pain, skin rashes, and disturbing behavior)
- have low salts levels in the body
Before taking HICOPE 25MG TABLET, inform your doctor if you:
- have glaucoma (high pressure in the eye)
- have difficulty passing urine (Ex. due to an enlarged prostate)
- have stomach problems
- have myasthenia gravis (a disorder which weakens muscle)
- have dementia
- have epilepsy (fits)
- have hyperthyroidism (overactive thyroid)
- have constipation
- have an imbalance of potassium or magnesium ions in your blood
Use in pediatrics:
Your doctor will prescribe the right dose depends on your child’s age, body weight and health condition. Consult your doctor before taking HICOPE 25MG TABLET.
Use in geriatrics:
HICOPE 25MG TABLET should be used with caution in elderly patients. Consult your doctor before taking the medicine.
INTERACTIONS
A. Drug-Drug interactions:
Before taking HICOPE 25MG TABLET, inform your doctor if you are taking any of the following medicine:
- medicines used to manage heart problems or high blood pressure (Ex. adrenaline or epinephrine, amiodarone, quinidine, disopyramide, sotalol)
- medicine used to manage sleeping disorders and epilepsy (Ex. barbiturates)
- medicine used to manage ulcers and heartburn (Ex. cimetidine)
- medicine used to manage vomiting and nausea (Ex. antiemetics)
- medicine used to manage Meniere’s disease (Ex. betahistine)
- medicines used as anesthetics
- medicine used as muscle relaxants
- medicine used to manage severe pain (Ex. opioids, methadone)
- medicine used as anticholinergic (including some medicines used for irritable bowel syndrome, asthma, or incontinence) (Ex. prucalopride)
- medicine used to manage breathing problems (Ex. aminophylline)
- medicine used to manage bacterial infections (Ex. benzylpenicillin salts and chloramphenicol sodium succinate, erythromycin, moxifloxacin, levofloxacin)
- medicine used for the chemotherapy (Ex. doxorubicin)
- medicine used as antidepressants (Ex. moclobemide or isocarboxazid, citalopram, escitalopram, amitriptyline)
- medicines used to manage anxiety (Ex. alprazolam)
- medicines used to manage psychosis (Ex. haloperidol)
- medicine used as antimuscarinic (Ex. atropine)
- other medicines used as antihistamines (Ex. azelastine, chlorpheniramine)
- medicines used for fungal infections (Ex. pentamidine)
- medicines used to manage malaria (Ex. mefloquine)
- medicines used to manage cancer (Ex. toremifene, vandetanib)
Overdosage:
If you or anyone else accidentally takes too much of HICOPE 25MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage nausea, vomiting, feeling sleepy, confusion, heart palpitations, unreactive pupils, the shakes, hallucinations, breathing problems, fits or low blood pressure.
SYNOPSIS
| Drug | : | Hydroxyzine |
| Pharmacological Category | : | Antihistamines |
| Therapeutic Indication | : | Manages anxiety and skin conditions (inflammation and itching) |
| Dosage Forms | : | Tablet, Syrup, Drops, Injection, Oral drops, Oral solution, Solution |
MORE INFORMATION
- Keep HICOPE 25MG TABLET out of reach of children
- Store at a temperature, not more than 25°C
FAQs ABOUT HICOPE 25MG TABLET
How does HICOPE 25MG TABLET work for allergies?
HICOPE 25MG TABLET works by decreasing the inflammation caused by allergies. It reduces inflammation by blocking the release of a natural chemical in our body, called histamine, that causes allergic symptoms such as swelling, redness, and pain.
Is it safe to use HICOPE 25MG TABLET if I have glaucoma?
HICOPE 25MG TABLET may cause increased pressure in the eye in patients having glaucoma. Consult your doctor before taking HICOPE 25MG TABLET.
What if I forget to take a dose of HICOPE 25MG TABLET?
If you forget a dose of HICOPE 25MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Can I stop taking HICOPE 25MG TABLET when I feel better?
No, do not stop taking HICOPE 25MG TABLET without consulting your doctor even if you are feeling better. Your symptoms may improve before the condition is completely cured. Therefore, for better and complete management, it is advised to continue your management for the prescribed duration.
What should I tell my doctor before starting management with HICOPE 25MG TABLET?
Before starting management with HICOPE 25MG TABLET, tell your doctor if you have any other health problems, like kidney, heart, or liver-related issues. This is because certain medical conditions may affect the management and may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect or get affected by HICOPE 25MG TABLET.
Can HICOPE 25MG TABLET be used in pregnant women?
HICOPE 25MG TABLET is generally not recommended to use among pregnant women unless considered clearly necessary. Consult your doctor before taking HICOPE 25MG TABLET.
REFERENCES
1. Randal A. Skidgel. Histamine, Bradykinin, and Their Antagonists. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page – 711-726.
2. KD. Tripathi. Histamine and Antihistaminics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 159-169.
3. Pierre-Michel Llorca, Christian Spadone, Olivier Sol, Anne Danniau, Thierry Bougerol, Emmanuelle Corruble, Michel Faruch, Jean-Paul Macher, Eric Sermet, Dominique Servant. Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study. Journal of Clinical Psychiatry. November 2002. [Accessed on 15th June 2022] https://pubmed.ncbi.nlm.nih.gov/12444816/
4. Amir Garakani1, James W. Murrough, Rafael C. Freire, Robyn P. Thom, Kaitlyn Larkin, Frank D. Buono and Dan V. Iosifescu. Pharmacotherapy of Anxiety Disorders: Current and Emerging Treatment Options. Frontiers Psychiatry. December 2020. [Accessed on 15th June 2022] https://www.frontiersin.org/articles/10.3389/fpsyt.2020.595584/full
5. Wenstrup, Susie MD; Hogan, Paul DO; Gonzalez, Ivan MD. Is hydroxyzine effective in reducing anxiety symptoms in adults? Journal of Evidence based Practice. October 2020. [Accessed on 15th June 2022] https://journals.lww.com/ebp/Citation/2020/10000/Is_hydroxyzine_effective_in_reducing_anxiety.25.aspx
6. Member States of the EEA. docetp.mpa.se. [Revised in December 2021] [Accessed on 15th June 2022] https://docetp.mpa.se/LMF/Hydroxyzine%20Bluefish%2010%20mg%20film-coated%20tablet%20ENG%20PL_09001bee807a3969.pdf
7. UCB Pharma Limited. www.hpra.ie. [Revised in August 2015] [Accessed on 15th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/2163517.PA0891_005_001.eefe53c6-4fb7-44d3-9339-d184c5ebb91d.000001Ucerax%2025mg%20Tablets%20PIL.150826.pdf
8. GSK limited. gskpro.com. [Revised in June 2019] [Accessed on 15th June 2022] https://gskpro.com/content/dam/global/hcpportal/en_SG/products/PDF/atarax/pdf/atarax_pi_ncds06si_approved_17sep19.pdf
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