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INTRODUCTION ABOUT MONTAIR BL TABLET
MONTAIR BL TABLET is a combination medication containing Bilastine and Montelukast. It is used to manage allergy symptoms such as runny nose, sneezing, and itchy eyes, as well as to reduce the symptoms of asthma.
The dosage of MONTAIR BL TABLET should be prescribed by your doctor. It is usually taken once daily with or without food. Follow the instructions on the prescription label carefully. Before taking MONTAIR BL TABLET inform your doctor if you have a history of liver or kidney disease, are pregnant or breastfeeding, are allergic to Bilastine, Montelukast, or any other ingredients in this medication.
MONTAIR BL TABLET is not recommended for use in patients with hereditary problems such as galactose intolerance, glucose-galactose malabsorption (inability of the body to absorb glucose and galactose sugars), and Lapp lactase deficiency (lactose intolerance). The medicine is also not indicated for use in patients suffering from acute asthmatic attacks.
The most common side effects associated with the use of MONTAIR BL TABLET are headache, abdominal pain, dry mouth and drowsiness. Consult your doctor if any of these symptoms worsen.
USES OF MONTAIR BL TABLET
- Relieves symptoms of allergic rhinitis, including sneezing and nasal congestion
- Manages seasonal allergies effectively
- Manages asthma attacks by reducing airway inflammation
Benefits of MONTAIR BL TABLET in Allergic rhinitis:
The combination of Bilastine and Montelukast works synergistically to address both the cause and symptoms of allergic rhinitis. Bilastine blocks histamines, preventing the allergic reaction that leads to sneezing, itching, and a runny nose. Montelukast reduces airway inflammation by inhibiting leukotrienes, substances that trigger nasal swelling and mucus production.
Benefits of MONTAIR BL TABLET in Seasonal allergies:
MONTAIR BL TABLET works by reducing inflammation and minimizing the body’s reaction to allergens. It helps to manage the recurrence of allergy symptoms, providing lasting protection throughout the allergy season. It helps reduce the likelihood of such issues by controlling nasal congestion and airway inflammation.
Benefits of MONTAIR BL TABLET in reducing Asthma attacks:
MONTAIR BL TABLET helps reduce asthma exacerbations caused by allergens such as pollen, dust mites, and mold. By controlling airway inflammation and reducing mucus production, also improves airflow, making breathing easier for patients with asthma or reactive airway diseases. Regular use of MONTAIR BL TABLET helps stabilize airways, reducing the likelihood of nighttime asthma attacks and ensuring uninterrupted sleep.
HOW MONTAIR BL TABLET WORKS
MONTAIR BL TABLET provides relief from allergic rhinitis where Bilastine works by blocking histamine (chemical messenger responsible for allergy), thus managing the occurrence of allergic symptoms, and Montelukast works by inhibiting the action of leukotrienes (chemicals responsible for inflammatory reactions), thus managing its occurrence and providing relief from associated symptoms of allergic rhinitis in affected individuals.
DIRECTIONS FOR USE
- Take MONTAIR BL TABLET as advised by your physician. Swallow the medicine with the glass of water. Do not crush or chew the medicine
- It should be taken before one hour or after two hours of taking food or fruit juice
Dosage and Administration:
- Standard Dose: Take one tablet daily, preferably in the evening or as directed by your healthcare provider
- With or Without Food: It can be taken with or without meals for convenience.
- Swallow Whole: Do not crush, chew, or break the tablet; take it with water for optimal absorption.
- Duration of Use: Use the medication consistently as prescribed, even if symptoms improve, to ensure long-term control of allergies or asthma.
Missed dose instructions for MONTAIR BL TABLET:
- If you forgot a dose of MONTAIR BL TABLET, take it as soon as you remember.
- Skip if Close to Next Dose: If it’s nearly time for your next dose, skip the missed one. Do not double up doses to make up for the missed tablet
Overdosage instructions for MONTAIR BL TABLET:
Taking more than the prescribed dose of MONTAIR BL TABLET may result in side effects such as:
- Severe headache
- Drowsiness or confusion
- Stomach pain or discomfort
Important Precautions:
- Allergic Reactions: Inform your doctor if you experience swelling, rash, or difficulty breathing.
- Drug Interactions: Avoid combining MONTAIR BL TABLET with alcohol or sedatives, as it may increase drowsiness. Always inform your healthcare provider about any other medications or supplements you are taking.
SIDE EFFECTS OF MONTAIR BL TABLET
Like all medicines, MONTAIR BL TABLET may cause certain side effects, although not everybody gets them.
Most common side effects of MONTAIR BL TABLET are:
- Headache
- Abdominal pain
- Dry mouth
- Drowsiness
When to consult your doctor?
- Signs of serious allergic reactions (hypersensitivity) such as swelling of the face, mouth, lips, tongue, and/or throat
- Signs of inflammation with eosinophilia, such as swelling of the lungs causing difficulty breathing
HOW TO MANAGE SIDE EFFECTS
Dizziness Or Drowsiness
Consult your doctor about switching your dose timing to bedtime. Take short walks during the day to boost alertness. Practice stretching stimulate energy levels. Maintain a consistent sleep schedule, aiming for 7-8 hours of rest. If drowsiness persists or worsens, consult your doctor to adjust the dosage or explore alternative medications.
Dry Mouth
Sip water frequently throughout the day. Carry a water bottle to ensure consistent hydration. Opt for ice chips for a refreshing way to stay hydrated. Eat foods with high water content, such as cucumbers, melons, and oranges. Avoid salty, spicy, or overly dry foods, which can irritate the mouth.
Headache
Drink plenty of water throughout the day. Avoid caffeine or sugary drinks, as they can sometimes exacerbate symptoms. If the headache is caused by tension, a warm compress on the neck and shoulders can help relax muscles and relieve pain. Lie down in a quiet, dimly lit or dark room. Practice deep breathing or mindfulness to relax.
Stomach Pain
Stick to a bland diet, including foods like bananas, rice, applesauce, and toast (the BRAT diet). Avoid spicy, fried, or acidic foods that may irritate the stomach. Place a hot water bottle or a warm towel on your abdomen for 15-20 minutes. Repeat as needed throughout the day.
WARNING & PRECAUTIONS
PREGNANCY
Consult your doctorAnimal and Human studies shows that MONTAIR BL TABLET did not show teratogenic effects. There are no sufficient studies in pregnant women to confirm, hence it should be used during pregnancy only if the potential benefits justify the potential risks to the fetus. It is generally recommended to avoid antihistamines unless necessary during the first trimester.
BREASTFEEDING
Use with CautionMONTAIR BL TABLET should be used with caution in breastfeeding women only if it is clearly necessary. Consult your doctor before taking the medicine.
DRIVING AND USING MACHINES
Use with CautionMONTAIR BL TABLET may cause dizziness and drowsiness in some individuals. Therefore, do not drive or handle heavy tools or machines if your ability is affected by this medicine.
KIDNEY
Use with CautionMONTAIR BL TABLET should be used with caution in patients with kidney problems such as moderate/severe renal impairment. Consult your doctor before taking the medicine.
LIVER
Use with CautionMONTAIR BL TABLET should be used with caution in patients with liver problems such as mild to moderate hepatic insufficiency. Consult your doctor before taking the medicine.
ALLERGY
ContraindicatedDo not take MONTAIR BL TABLET if you are allergic to Bilastine, Montelukast, and/or any other ingredients of this medicine.
LUNGS
ContraindicatedMONTAIR BL TABLET is not recommended for use in patients with lung problems such as acute asthma attacks. Consult your doctor before taking the medicine.
USE IN PEDIATRICS
Consult your doctorMONTAIR BL TABLET can be used in adolescents aged 15 years or older. It is not suitable for use in children aged below 15 years of age.
USE IN GERIATRICS
Use with CautionMONTAIR BL TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking MONTAIR BL TABLET.
OTHERS
MONTAIR BL TABLET is not recommended for use if you:
- have hereditary problems such as galactose intolerance, glucose-galactose malabsorption (inability of the body to absorb glucose and galactose sugars), and Lapp lactase deficiency (lactose intolerance)
SAFETY ADVICE
Quick Tips:
- Take once daily, preferably in the evening, or as directed by your doctor
- Swallow the tablet with water, with or without food
- Grapefruit Juice can interfere with Montelukast metabolism
- Common side effects are drowsiness, dry mouth, and mild headache
- Take consistently at the same time each day for optimal effect
- Pair with an allergy-friendly lifestyle: reduce exposure to allergens like dust, pollen, and pet dander
- Safe for Long-Term Use: It can be used for ongoing asthma and allergy management under medical supervision
INTERACTIONS
A. Drug-Drug Interactions:
Before taking MONTAIR BL TABLET inform to your doctor, if you are taking any of these medicines:
Antifungals (e.g., Ketoconazole)
- Interaction: Antifungals are potent inhibitors of the CYP3A4 enzyme, which metabolizes Montelukast. Bilastine is absorbed in the gastrointestinal tract, and antifungals that alter gut motility or pH (e.g., ketoconazole) may reduce its effectiveness.
- Effect: Increased Montelukast levels in the blood can heighten the risk of side effects, such as headaches, nausea, or mood changes. Bilastine depends on P-glycoprotein (P-gp) transport for absorption. Some antifungals inhibit P-gp, potentially increasing Bilastine levels and enhancing side effects like drowsiness or dizziness.
Antibiotics (eg., Erythromycin)
- Interaction: Antibiotics like erythromycin or clarithromycin (macrolides) can inhibit CYP3A4, leading to higher Montelukast blood levels and increasing the risk of side effects such as headaches, gastrointestinal discomfort, or mood changes.
- Effect: Enhanced side effects like drowsiness, dizziness, or fatigue.
Immunosuppressants (eg., Cyclosporine)
- Interaction: Montelukast is metabolized by the liver enzyme CYP3A4, and immunosuppressants like cyclosporine can inhibit this enzyme. Bilastine relies on the P-glycoprotein transporter for its absorption and distribution.
- Effect: Elevated Montelukast levels in the bloodstream, leading to side effects such as headaches, mood changes, or gastrointestinal discomfort. Increased Bilastine levels can amplify side effects such as drowsiness, dizziness, and fatigue.
B. Drug-Food Interactions:
- Avoid having grapefruit juice while taking MONTAIR BL TABLET since it reduces the effect of the medicine.
- There are no direct interactions with caffeine, but in sensitive individuals, caffeine combined with Bilastine may increase anxiety or restlessness.
SYNOPSIS
| Drug | : | Bilastine, Montelukast |
| Pharmacological Category | : | Histamine antagonists, Leukotriene antagonists |
| Therapeutic Indication | : | Allergic rhinitis |
| Dosage Forms | : | Tablet, Suspension |
MORE INFORMATION
Duration of action:
When used together, MONTAIR BL TABLET offers 24-hour relief for symptoms of respiratory allergies, including allergic rhinitis and asthma. Both medicines are designed for once-daily administration, ensuring consistent efficacy over a full day.
Onset of action:
Together, Bilastine offers rapid symptomatic relief from allergies, while Montelukast provides sustained anti-inflammatory action. Most patients experience the combined therapeutic effects within 2-3 hours of taking the medication.
FAQs ABOUT MONTAIR BL TABLET
Q: Can MONTAIR BL TABLET be used for asthma?
A:Yes. MONTAIR BL TABLET helps in reducing asthma symptoms by reducing airway inflammation. Consult your doctor for more details.
Q: Is it safe to take MONTAIR BL TABLET during pregnancy?
A: It is essential to consult your doctor before taking this medication if you are pregnant or planning to conceive.
Q: What is MONTAIR BL TABLET used for?
A: It is a combination medication primarily used to manage allergic rhinitis (seasonal or perennial allergies) and asthma. Bilastine is a non-sedating antihistamine that helps relieve symptoms like sneezing, itchy or runny nose, and watery eyes. Montelukast is a leukotriene receptor antagonist that reduces inflammation in the airways, making it effective for asthma and allergy-related symptoms.
Q: How should I take MONTAIR BL TABLET?
A: Follow your healthcare provider's instructions for dosage and timing, especially if taking other medications.
Q: What are the common side effects of MONTAIR BL TABLET?
A:While most people tolerate this combination well, some may experience mild side effects, including Drowsiness or dizziness (more common with Bilastine, though it is less sedating than other antihistamines), Headache or stomach discomfort, Coughing or sore throat (Montelukast) or Mood changes (rare, but associated with Montelukast).
Q: Can I take MONTAIR BL TABLET with other medications?
A: It generally has a low risk of interacting with other medications. However, inform your doctor if you are taking CYP3A4 inhibitors (e.g., ketoconazole, erythromycin), Sedatives or other antihistamines (to avoid enhanced sedative effects), Antifungals, antibiotics, or immunosuppressants, as they may alter the drug’s effectiveness. Always check with your healthcare provider before combining medications.
Q: Is MONTAIR BL TABLET safe for children?
A: Your pediatrician will prescribe the appropriate dosage based on the child's age and condition. Consult your doctor before giving this medication to a child.
Q: How long does it take for MONTAIR BL TABLET to work?
A: Bilastine typically starts working within 1 to 3 hours, providing rapid relief from allergy symptoms. Montelukast may take 1-2 days to show its full effect in reducing asthma symptoms or preventing allergic rhinitis. For optimal results, it is essential to take both medications consistently on a daily basis.
Q: Can I drink alcohol while taking MONTAIR BL TABLET?
A:Avoid alcohol while taking Bilastine, as it may increase the sedative effects and cause drowsiness, dizziness, or difficulty concentrating. Although Montelukast does not directly interact with alcohol, it’s advisable to limit alcohol consumption to avoid potential side effects of both drugs.
Q: What should I do if I forget a dose of MONTAIR BL TABLET?
A:If you forget a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not take two doses at once to make up for a missed dose. If you have missed several doses, consult your healthcare provider for guidance.
Q: How should I store MONTAIR BL TABLET?
A: Store at room temperature, away from moisture and direct light. Keep the medication in its original packaging or tightly sealed container to protect it from air and moisture. Keep out of reach of children and pets.
Q: Can I use MONTAIR BL TABLET during pregnancy or breastfeeding?
A: Pregnancy: Consult your doctor before using, if you are pregnant, as the safety profile during pregnancy is not fully established. Breastfeeding: Both medications pass into breast milk in small amounts. Speak with your doctor about the risks and benefits of using this combination during breastfeeding.
REFERENCES
1. Sidhartha D. Ray. Antihistamines (H1 receptor antagonists). Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions: Volume 43. First edition. 2021. Page 190.
2. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page 228.
3. Federico Lavorini, Andrea Matucci, Oliviero Rossi, Massimo Pistolesi, SKY study investigators. Concomitant bilastine and montelukast as additive therapy for seasonal allergic rhinoconjunctivits and mild-to-moderate asthma. The SKY study. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. October 2019. [Accessed on 10th July 2024] click here
4. Ciplamed. BILAFAV M Tablets. [Revised in March 2020] [Accessed on 10th July 2024] click here
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