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INTRODUCTION ABOUT STATPURE CV 10 CAPSULE
STATPURE CV 10 CAPSULE is a combination medicine used to lower bad cholesterol (LDL) and triglyceride levels and reduce the risk of heart-related complications like heart attack, angina (chest pain), and stroke. It also limits the formation of harmful blood clots within the blood vessels which reduce the risk of atherosclerosis and other blood vessel problems.
STATPURE CV 10 CAPSULE can be taken with or without food, as directed by your doctor. For best results, take it consistently at the same time each day to maintain stable levels in your body. Follow the dosage and therapy duration as prescribed by your doctor, even if you start feeling better before completing the course. Incorporating lifestyle changes, such as a low-fat diet, regular exercise, and avoiding smoking, can enhance the effectiveness of this medication.
Before taking this medication, inform your doctor if you have a history of liver or kidney problems, bleeding disorders, or if you are pregnant, planning to become pregnant, or breastfeeding. Additionally, let your doctor know about any other medications you are taking, as they may interact with this treatment.
While taking this medicine, avoid alcohol consumption as it may increase liver-related side effects.
STATPURE CV 10 CAPSULE generally increases your tendency to bleed, and so if you cut or injure yourself, it may take a little longer for the bleeding to stop. Bleeding for minor injuries like small cuts or shaving is of no concern.
However, if you experience excessive bleeding for a prolonged period, contact your doctor. The most common side effects of taking STATPURE CV 10 CAPSULE are headache, dizziness, nausea, stomach pain, muscle pain or increased bleeding tendency. Consult your doctor if any of the side effects worsen.
If you notice symptoms such as yellowing of the skin, muscle pain, or dark-colored urine, consult your doctor immediately. Regular liver function tests may also be recommended during treatment.
USES OF STATPURE CV 10 CAPSULE
- High cholesterol levels and triglyceride levels
- Blood clots and associated heart complications
Key Benefits of STATPURE CV 10 CAPSULE:
- Helps lower "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL) levels.
- Reduces the risk of heart attack, stroke, and other cardiovascular complications.
- Supports improved blood flow and reduced plaque formation in arteries.
- Aids in the prevention of atherosclerosis and maintains overall heart health.
HOW STATPURE CV 10 CAPSULE WORKS
STATPURE CV 10 CAPSULE combines two active ingredients, Rosuvastatin and Clopidogrel, which work together to improve heart health and reduces the risk of blood clot formation. Rosuvastatin lowers "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL), helping reduce cholesterol accumulation in the arteries. Clopidogrel is an antiplatelet agent that stops platelets from clumping together, minimizing the risk of blood clots. Together, they improve blood flow, reduce blockages, and lower the risk of heart attack and stroke.
DIRECTIONS FOR USE
- Take STATPURE CV 10 CAPSULE as prescribed by your doctor, preferably at a fixed time each day, to maintain consistent levels in the body.
- It can be taken with or without food, as directed by your healthcare provider.
- Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Dosage and Administration:
- The dosage will be determined by your doctor based on your medical condition, age, and response to treatment.
- Follow the prescribed dosage schedule strictly. Do not alter the dose without consulting your doctor.
Missed Dosage Instructions for STATPURE CV 10 CAPSULE:
- If you forgot to take a dose, take it as soon as you remember. If it’s close to the time of your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.
Overdosage:
- In case of accidental overdose, seek immediate medical attention. Symptoms of overdose may include dizziness, severe headache, or unusual bleeding. Always keep the medication out of reach of children to avoid accidental ingestion.
SIDE EFFECTS OF STATPURE CV 10 CAPSULE
Like all medicines, STATPURE CV 10 CAPSULE may cause certain side effects although not everybody gets them.
Some of the most common side effects of STATPURE CV 10 CAPSULE are:
- Headache, dizziness
- Stomach pain, indigestion, constipation, diarrhoea
- Nausea or vomiting
- Muscle pain
- General weakness
- Diabetes
- Unusual bleeding
- Skin rash, itching, or other skin reactions
When to consult your doctor? –
Stop taking this medicine and inform your doctor immediately if you experience any of the following side effects:
- Severe allergic reactions (such as skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue, and/or throat with difficulty breathing or swallowing)
- Fever, signs of infection, or extreme tiredness
- Signs of liver problems (such as jaundice (yellowing of the skin and the whites of the eyes) with or without bleeding that can appear as red pinpoint dots under the skin and/or confusion)
- Rhabdomyolysis (prolonged unusual muscle weakness, tenderness, or pain associated with general weakness or fever)
- Thrombotic thrombocytopenic purpura (a blood disorder causing blood clots to form in capillaries, which may lead to high fever, severe bleeding under the skin resembling red pinpoint dots, with or without unexplained extreme tiredness, confusion, or jaundice)
To know more about the safety of this medicine,
HOW TO MANAGE SIDE EFFECTS
Constipation
- Increase fiber intake with fruits, vegetables, and whole grains for regular bowel movements.
- Drink plenty of water to keep your digestive system hydrated.
- Exercise regularly to stimulate bowel function and ease constipation.
- Try natural remedies like prunes or warm water with lemon to encourage bowel movements.
- Avoid excessive caffeine and processed foods that can worsen constipation.
Diarrhea
- Stay hydrated with water or oral rehydration solutions to replenish lost fluids.
- Follow a bland diet (BRAT: bananas, rice, applesauce, toast) for digestive support.
- Avoid spicy foods, alcohol, and caffeine, which may aggravate symptoms.
- Eat small, frequent meals to avoid overloading your digestive system.
- Rest and limit physical activities to support recovery.
Headache
- Rest in a dark, quiet room to reduce headache intensity.
- Keep hydrated with water to prevent dehydration-related headaches.
- Apply a cold compress to your forehead or neck to alleviate pain.
- Try stress-relieving activities like deep breathing exercises or meditation.
- Consult your doctor before taking pain relievers to ensure they are safe to use with this medicine.
Muscle Cramps
- Use a heating pad or take a warm bath to relax tight muscles.
- Perform gentle stretching exercises to relieve stiffness.
- Ensure proper hydration and replenish electrolytes with water.
- Apply a gentle massage to the affected area to improve blood circulation.
- Avoid strenuous physical activities until the pain improves.
Stomach Pain
- Opt for small, frequent meals to ease stomach discomfort.
- Avoid spicy, greasy foods and carbonated drinks to prevent irritation.
- Use a warm compress on your abdomen for relief from cramps.
- Stay upright after eating to prevent acid reflux and indigestion.
- Try natural remedies like chamomile tea or peppermint tea to soothe the stomach.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedSTATPURE CV 10 CAPSULE is not safe for use in pregnant women. Clinical studies have indicated significant harmful side effects in growing baby. Therefore, inform your doctor before taking STATPURE CV 10 CAPSULE if you are pregnant or think you may be pregnant.
Women of childbearing potential should use a suitable contraceptive method to avoid pregnancy while taking STATPURE CV 10 CAPSULE.
BREASTFEEDING
Consult your doctorIt is not known whether STATPURE CV 10 CAPSULE passes through breast milk. As a precaution, breastfeeding should be avoided while using STATPURE CV 10 CAPSULE. Consult your doctor for advice.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any heavy tools or machines if you experience dizziness after taking STATPURE CV 10 CAPSULE.
ALCOHOL
Consult your doctorAvoid consumption of alcohol while taking STATPURE CV 10 CAPSULE, as it could aggravate your existing disease condition.
KIDNEY
Consult your doctorSTATPURE CV 10 CAPSULE is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with mild to moderate kidney problems. Therefore, consult your doctor for advice. Dosage adjustment and periodic monitoring of kidney functions are essential in such patients.
LIVER
Consult your doctorSTATPURE CV 10 CAPSULE is not recommended for use in patients with severe liver disease. It should be used with caution in patients with other liver disease. Therefore, consult your doctor for advice. Dosage adjustment and periodic monitoring of liver functions are essential in such patients.
ALLERGY
ContraindicatedDo not take STATPURE CV 10 CAPSULE if you are allergic to Clopidogrel or Rosuvastatin.
LUNGS
Use with CautionSTATPURE CV 10 CAPSULE should be taken with caution in patients with severe respiratory failure. Consult your doctor before taking STATPURE CV 10 CAPSULE.
USE IN PEDIATRICS
RiskySTATPURE CV 10 CAPSULE is not suitable for use in children and adolescents (aged below 18 years) due to risk of bleeding. Therefore, consult your doctor for advice.
USE IN GERIATRICS
Use with CautionSTATPURE CV 10 CAPSULE should be used with caution in elderly patients (aged 65 years or above). Proper dose adjustments and careful monitoring are required in such patients. Consult your doctor before taking STATPURE CV 10 CAPSULE.
OTHERS
STATPURE CV 10 CAPSULE is not recommended for use if you:
- Have or had repeated or unexplained muscle aches or pains in the past
- Have a family history of muscle problems
- Have previous history of muscle problems while taking other cholesterol-lowering medicines
- Have problems in the thyroid gland
- Are alcoholic
- Have any condition that can increase the risk of bleeding (such as the presence of a stomach ulcer, blood disorders, ischemic stroke (a blood clot in an artery supplying your brain), a recent serious injury, or have any upcoming surgery (including dental) or recently had one)
Before taking STATPURE CV 10 CAPSULE, inform your physician if you:
- Have diabetes or are at risk of developing diabetes (Ex. being overweight, having high levels of glucose in your blood, or having high blood pressure)
SAFETY ADVICE
Expert Advice to Maximize the Effects of STATPURE CV 10 CAPSULE:
- Ensure that you take STATPURE CV 10 CAPSULE exactly as directed by your healthcare provider. Do not adjust the dose or stop taking it without consulting your doctor.
- Take the capsule at the same time every day to help maintain consistent blood levels for optimal results.
- Have your cholesterol and liver function tested as directed by your doctor to track progress and ensure safety.
- Drink plenty of water throughout the day to help flush out toxins and support liver health while taking STATPURE CV 10 CAPSULE.
- Limit alcohol intake as it can increase the risk of liver damage when taking rosuvastatin, one of the active ingredients in ROSULIP CV.
INTERACTIONS
A. Drug-Drug interactions:
1. Warfarin:
Combining STATPURE CV 10 CAPSULE and warfarin (a blood thinner) can increase the risk of bleeding. The Clopidogrel present in the medicine reduces blood clot formation, while warfarin also interferes with clotting factors. Together, they may enhance each other's effects, leading to an increased risk of bruising, bleeding, and hemorrhage. Close monitoring of INR (International Normalized Ratio) levels is recommended for patients taking both warfarin and these drugs?
2. Cyclosporine:
Cyclosporine, an immunosuppressant used primarily in organ transplant patients, can significantly increase the blood levels of rosuvastatin. As a result, the risk of rosuvastatin-related side effects, such as muscle pain or myopathy, is heightened. Caution is advised when combining these medications, and dose adjustments may be necessary?
3. Antibiotics
Certain antibiotics, such as erythromycin and clarithromycin, can interfere with the metabolism of rosuvastatin, leading to higher blood levels of the statin. This can increase the risk of statin-associated muscle toxicity. Additionally, antibiotics like penicillin and cephalosporins may alter the effectiveness of clopidogrel by inhibiting its metabolism?.
4. Antifungals
Antifungal medications like ketoconazole and itraconazole can also raise rosuvastatin levels by inhibiting the liver enzymes involved in metabolizing the drug. This increases the risk of side effects like muscle aches, liver damage, and myopathy. It’s important to monitor the patient closely when combining rosuvastatin with these antifungals?
5. Other Lipid-Lowering Agents
When combining rosuvastatin with other lipid-lowering drugs like gemfibrozil, niacin, or other statins, the risk of side effects, especially muscle-related problems like rhabdomyolysis, is significantly increased. These agents can potentiate the effects of rosuvastatin, leading to an increased risk of adverse effects on muscles and kidneys?
6. HIV Protease Inhibitors (e.g., Ritonavir): These may increase the concentration of rosuvastatin in the blood, increasing the risk of adverse effects.
7. Antacids containing Aluminum or Magnesium: Can interfere with the absorption of rosuvastatin, reducing its effectiveness.
Drug-Food Interactions for STATPURE CV 10 CAPSULE:
- Grapefruit: Grapefruit and grapefruit juice may increase the levels of statins in the blood, leading to an increased risk of side effects, especially muscle problems.
- Alcohol: Excessive alcohol consumption can increase the risk of liver damage when combined with rosuvastatin.
- High-fat meals: High-fat meals can affect the absorption of rosuvastatin and may reduce its effectiveness.
- Vitamin K-rich foods (e.g., leafy greens): While not directly interacting with Cardirose CV, it may alter the effectiveness of blood-thinning medications used concurrently (like warfarin).
Always consult a healthcare provider or pharmacist before starting new medications or making changes to your diet to avoid potential interactions.
SYNOPSIS
| Drug | : | Rosuvastatin and Clopidogrel |
| Pharmacological Category | : | Antiplatelets, HMG-CoA reductase inhibitors |
| Therapeutic Indication | : | Bad Cholesterol and triglyceride levels, heart problems |
| Dosage Forms | : | Capsule, Tablet |
MORE INFORMATION
Diet Tips to Enhance the Effectiveness of STATPURE CV 10 CAPSULE:
A heart-healthy diet plays a crucial role in managing cholesterol and enhancing the effectiveness of STATPURE CV 10 CAPSULE:- Increase Fiber Intake: Eat more fiber-rich foods like fruits, vegetables, whole grains, and legumes. Fiber helps lower LDL cholesterol and promotes digestive health.
- Focus on Healthy Fats: Include omega-3 fatty acids (found in fish like salmon and mackerel) and monounsaturated fats (found in olive oil, avocados, and nuts) to help improve heart health.
- Limit Saturated and Trans Fats: Avoid fatty cuts of meat, fried foods, and processed snacks that can raise bad cholesterol levels.
- Reduce Salt Intake: Limit your consumption of high-sodium foods, such as processed foods, canned soups, and fast food, to support healthy blood pressure.
- Stay Hydrated: Drink plenty of water to help your kidneys filter out waste products and support the absorption of nutrients.
Lifestyle Advice for Heart Health While Taking STATPURE CV 10 CAPSULE:
- Regular exercise, such as brisk walking, swimming, or cycling for at least 150 minutes per week, can improve cholesterol levels and promote overall heart health.
- Quitting smoking is one of the most effective ways to lower the risk of heart disease, as smoking increases bad cholesterol and damages blood vessels.
- Maintaining a healthy weight, achieved through a balanced diet and regular physical activity, can help reduce cholesterol levels.
- Chronic stress has a negative impact on heart health, and relaxation techniques like meditation, deep breathing, or yoga may help manage stress.
- Getting 7-8 hours of quality sleep each night is essential, as poor sleep can contribute to high cholesterol and other heart-related issues.
Incorporating these dietary and lifestyle changes, alongside the prescribed STATPURE CV 10 CAPSULE, can enhance its effectiveness and support better heart health. It is always important to follow a healthcare provider's guidance to achieve optimal results.
FAQs ABOUT STATPURE CV 10 CAPSULE
Q: What is STATPURE CV 10 CAPSULE used for?
A: STATPURE CV 10 CAPSULE is primarily used to lower cholesterol levels and reduce the risk of heart attacks, strokes, and other cardiovascular conditions. It contains rosuvastatin (a statin) and clopidogrel (an antiplatelet agent), which work together to lower "bad" cholesterol (LDL) and triglycerides, and prevent blood clot formation.
Q: What are the common STATPURE CV 10 CAPSULE side effects?
A: The most common side effects of STATPURE CV 10 CAPSULE include muscle pain or weakness, stomach pain, nausea, or constipation, headaches or dizziness, elevated liver enzymes (may require monitoring) and increased risk of bleeding (due to clopidogrel) If you experience severe side effects like unexplained muscle pain, weakness, yellowing of the skin or eyes, or dark urine, seek medical attention immediately.
Q: How does STATPURE CV 10 CAPSULE work?
A: STATPURE CV 10 CAPSULE works by combining two active ingredients, Rosuvastatin lowers cholesterol by inhibiting the enzyme HMG-CoA reductase, which reduces the production of LDL (bad cholesterol) and triglycerides. Clopidogrel reduces formation of blood clots by inhibiting platelet aggregation, which helps to reduce the risk of heart attack and stroke.
Q: Is STATPURE CV 10 CAPSULE effective for high cholesterol?
A: Yes, STATPURE CV 10 CAPSULE is effective in managing high cholesterol. Rosuvastatin, the active ingredient, is a proven statin that helps lower LDL cholesterol levels and triglycerides, reducing the risk of cardiovascular diseases.
Q: How to take STATPURE CV 10 CAPSULE?
A: Take STATPURE CV 10 CAPSULE as prescribed by your doctor. It can be taken with or without food, usually once a day. Swallow the capsule whole with water. Do not crush or chew it. Try to take it at the same time each day to help remember your dose.
Q: STATPURE CV 10 CAPSULE dosage and administration
A: The recommended dose of STATPURE CV 10 CAPSULE is typically one capsule per day, depending on your condition and your doctor's instructions. The dosage may vary based on your cholesterol levels, medical history, and other factors. Always follow your doctor's advice for the proper dosage.
Q: Can STATPURE CV 10 CAPSULE cause muscle pain?
A: Yes, one of the potential side effects of STATPURE CV 10 CAPSULE, especially due to the rosuvastatin component, is muscle pain or weakness (myopathy). If you experience persistent or severe muscle pain, contact your healthcare provider.
Q: What are the interactions with STATPURE CV 10 CAPSULE?
A: STATPURE CV 10 CAPSULE can interact with other medications, including
Anticoagulants (e.g., warfarin): Increases the risk of bleeding.
Other statins: Increases the risk of muscle problems and liver damage.
Cyclosporine: May increase rosuvastatin levels, raising the risk of side effects.
Fibrates (e.g., fenofibrate): Increases the risk of muscle damage. Always inform your doctor of all medications you're taking, including over-the-counter drugs and supplements.
Q: Can I take STATPURE CV 10 CAPSULE with other cholesterol medications?
A: You should avoid combining STATPURE CV 10 CAPSULE with other statins unless advised by your doctor, as it may increase the risk of side effects, particularly muscle problems. Your doctor may prescribe additional cholesterol-lowering medications if necessary, but always follow their guidance on medication combinations.
Q: Is STATPURE CV 10 CAPSULE safe during pregnancy or breastfeeding?
A: STATPURE CV 10 CAPSULE is not recommended during pregnancy and breastfeeding. The active ingredients may harm the fetus or infant. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medication.
Q: How long should I take STATPURE CV 10 CAPSULE?
A: The duration of therapy with STATPURE CV 10 CAPSULE depends on your medical condition and the doctor’s recommendations. In most cases, this medication is used long-term to maintain healthy cholesterol levels and prevent heart-related issues. Always follow your doctor’s instructions for continued use.
Q: Can STATPURE CV 10 CAPSULE cause blood in stool?
A: STATPURE CV 10 CAPSULE generally increases your tendency to bleed and can cause black or blood-stained stools due to increased bleeding in the gut. If you have any existing condition that can make you bleed more (such as the presence of a stomach ulcer), please inform your doctor before taking STATPURE CV 10 CAPSULE.
Q: What to do if I forget to take STATPURE CV 10 CAPSULE?
A: You should take STATPURE CV 10 CAPSULE immediately when you remember. If it is time for your next dose of STATPURE CV 10 CAPSULE, skip the dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
REFERENCES
- KD. Tripathi. Drugs Affecting Coagulation, Bleeding, and Thrombosis. Essentials of Medical Pharmacology. Seventh Edition. 2013. Pages- 630 & 632-633.
- Gregory G Schwartz, Michael A. Bolognese, Benoit P. Tremblay, Richard Caplan, Howard Hutchinson, Ali Raza, and Michael Cressman. Efficacy and safety of rosuvastatin and atorvastatin in patients with hypercholesterolemia and a high risk of coronary heart disease: a randomized, controlled trial. NIH National Library of Medicine, National Center for Biotechnology Information. Pubmed.gov. July 2004. [Accessed on 12th July 2024] click here
- Torrent Pharmaceuticals Ltd. Rozuplatt. Torrentian.com. [Revised in August 2020] [Accessed on 12th July 2024] click here
- Exmo Biogenics Pvt Ltd. Roscad-CV 5/10. [Accessed on 12th July 2024] click here
- Llyod Healthcare. Rosloy CV. [Accessed on 12th July 2024] click here
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