Unparalleled Performance, Improving and Simplifying Gene Expression Analysis

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	Genomics
	The latest genomics news from News Medical

Unparalleled Performance, Improving and Simplifying Gene Expression Analysis

The UltraMarathonRT® Two-Step RT-qPCR Kit sets a new standard in RNA quantification, delivering unmatched sensitivity, reliability, and robustness for researchers. Most RT enzymes used in RT-qPCR have low processivity and are only able to provide partial transcript coverage which restricts qPCR primer design to limited regions of the transcript. UltraMarathonRT is unphased by GC stretches and secondary structures of RNA templates, this kit provides consistent Ct values regardless of primer location ensuring accurate, reliable results each time.

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			Promising gene therapy could transform heart failure treatment A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model.

			Unveiling the role of gene inactivation in human disease New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms.

	TTUHSC researcher to uncover mechanisms that regulate gene expression in Alzheimer's disease More than six million Americans are affected by Alzheimer's disease, a form of dementia marked by accumulation of amyloid-β within the brain. Amyloid-β is a relatively small protein that forms toxic plaques in the brain contributing to the harmful effects of Alzheimer's disease.

	Y chromosome’s unexpected impact on aging and disease in men Loss of the Y chromosome (LOY) in men, a dynamic mutation linked to aging, impairs immune function and increases risks of cancer, Alzheimer’s, and cardiovascular diseases, making it a promising biomarker and therapeutic target.

	New AI method predicts gene activity in human cells Using a new artificial intelligence method, researchers at Columbia University Vagelos College of Physicians and Surgeons can accurately predict the activity of genes within any human cell, essentially revealing the cell's inner mechanisms.

	Gene variant in Andean populations could help predict blood cancer treatment outcomes Two researchers from Huntsman Cancer Institute at the University of Utah (the U) have discovered a gene variant found in high-altitude Andean populations that they believe could be a new biomarker for predicting the severity of diseases and treatment responses for certain types of blood cancer.

	NIH funding supports innovative lupus research using DNA mimic molecules Lupus causes chronic pain, fatigue, and potentially organ damage for 1.5 million Americans and is a challenge for researchers trying to find better treatments.

	DNA Barcoding Reveals Hidden Species When it comes to species diversity, the Earth is nearly unthinkable. Between two and three million species have been identified by scientists, but there are many more about which people know nothing.

	Gene therapy to prevent stillbirth and premature delivery developed Researchers investigate the effectiveness of placental nano-based insulin-like 1 growth factor gene therapy to correct fetal growth restriction.

	RNAConnect Debuts The New UltraMarathonRT® RT-qPCR Kit to Improve Reliability Of Gene Expression Analysis UltraMarathonRT® RT-qPCR Kit offers unmatched data reliability and sensitivity for gene expression studies, streamlining workflows and preserving RNA integrity.