Question

5. Enamines as nucleophiles a. Alkylation of enamines: Draw the intermediate in brackets which is the alkylated iminium ion then draw the product which is the alkylated ketone. $CH_3$ N $CH_3$ CI + $H_3O^+$ b. Acylation of enamines: Draw the intermediate in brackets which is the acylated iminium ion then draw the product which is the acylated ketone ($\beta$-diketone). N O CI $H_3O^+$ 6. Design a short synthesis for each target (a-c) below using the following methods: alkylation of an enolate, alkylation of an enamine or acylation of an enamine. $CH_3$ $CH_3$ O a. $CH_3$ $CH_3$ $CH_3$ b.

          5. Enamines as nucleophiles
a. Alkylation of enamines: Draw the intermediate in brackets which is the alkylated iminium ion
then draw the product which is the alkylated ketone.
$CH_3$
N
$CH_3$
CI
+
$H_3O^+$
b. Acylation of enamines: Draw the intermediate in brackets which is the acylated iminium ion
then draw the product which is the acylated ketone (\(\beta\)-diketone).
N
O
CI
$H_3O^+$
6. Design a short synthesis for each target (a-c) below using the following methods: alkylation of
an enolate, alkylation of an enamine or acylation of an enamine.
$CH_3$
$CH_3$
O
a.
$CH_3$
$CH_3$
$CH_3$
b.

5. Enamines as nucleophiles
a. Alkylation of enamines: Draw the intermediate in brackets which is the alkylated iminium ion
then draw the product which is the alkylated ketone.
CH3
N
CH3
CI
+
H3O^+
b. Acylation of enamines: Draw the intermediate in brackets which is the acylated iminium ion
then draw the product which is the acylated ketone (β-diketone).
N
O
CI
H3O^+
6. Design a short synthesis for each target (a-c) below using the following methods: alkylation of
an enolate, alkylation of an enamine or acylation of an enamine.
CH3
CH3
O
a.
CH3
CH3
CH3
b.

Added by Beatriz B.

Guest user

Question

Instant Answer