Möller, D.F.; Mohorko, B.; Aschauer, T.E.; Schwager, T.; Aschauer, M.A. Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function. J. Vasc. Dis.2024, 3, 212-223.
Möller, D.F.; Mohorko, B.; Aschauer, T.E.; Schwager, T.; Aschauer, M.A. Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function. J. Vasc. Dis. 2024, 3, 212-223.
Möller, D.F.; Mohorko, B.; Aschauer, T.E.; Schwager, T.; Aschauer, M.A. Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function. J. Vasc. Dis.2024, 3, 212-223.
Möller, D.F.; Mohorko, B.; Aschauer, T.E.; Schwager, T.; Aschauer, M.A. Retrospective Correlation of the Circulation Time of Test Bolus Injections in MR Angiography and Cardiac Function. J. Vasc. Dis. 2024, 3, 212-223.
Abstract
This retrospective study examines 248 test-bolus examinations preceding contrast-enhanced magnetic resonance angiography (CE-MRA) to extract clinically relevant data for critical limb ischemia (CLI) management. Methods involved a retrospective review of test-bolus exams, analysing 60 graphs for time-to-peak (TTP), full-width half-maximum (FWHM) time, and time to continual rise in signal intensity. These values were correlated with heart function parameters (ejection fraction, ASA-Classification, Lee-Index, and MET-Score). Results indicate a mean TTP of 31.2 ± 7.3s, showing a correlation between ejection fraction and ASA classification. Patients with atrial fibrillation exhibited prolonged TTP compared to those without. Despite population heterogeneity, findings facilitate risk stratification for limb-saving interventions in CLI. TTP emerges as a potential clinical cardiovascular parameter and a risk factor for vascular interventions. Given the variation in injection protocols across centres, this study underscores the importance of precise bolus arrival time documentation for future multicentre studies.
Keywords
test-bolus examination; magnetic resonance angiography; time-to-peak; peripheral arterial disease
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
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