Molecular structure of Methyl Salicylate, CAS Number: 119-36-8
Methyl Salicylate (CAS 119-36-8)
Alternate Names:
Wintergreen oil; Salicylic acid methyl ester; Methyl 2-hydroxybenzoate
Application:
Methyl Salicylate is an anticoagulant that interrupts the vitamin K1-epoxide cycle
CAS Number:
119-36-8
Purity:
≥98%
Molecular Weight:
152.15
Molecular Formula:
C8H8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Methyl Salicylate is an organic ester compound derived from salicylic acid and methanol that acts as an anticoagulant by interruption of the vitamin K1-epoxide cycle. It is widely used in the chemical, pharmaceutical, and food industries as a flavoring agent, preservative, and fragrance. Methyl Salicylate acts by inhibiting the activity of cyclooxygenase-2 (COX-2), an enzyme involved in the production of prostaglandins, which are involved in inflammation and pain. It has also been found to inhibit the release of pro-inflammatory cytokines such as TNF-α and IL-1β, and to reduce the production of nitric oxide. In addition, Methyl Salicylate possess antioxidant, antifungal, and antibacterial properties.
Methyl Salicylate (CAS 119-36-8) References:
- Are one or two dangerous? Methyl salicylate exposure in toddlers. | Davis, JE. 2007. J Emerg Med. 32: 63-9. PMID: 17239735
- Fragrance material review on methyl salicylate. | Lapczynski, A., et al. 2007. Food Chem Toxicol. 45 Suppl 1: S428-52. PMID: 18031908
- Naturally occurring methyl salicylate glycosides. | Mao, P., et al. 2014. Mini Rev Med Chem. 14: 56-63. PMID: 24329991
- A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate. | Greene, T., et al. 2017. Crit Rev Toxicol. 47: 98-120. PMID: 27834107
- Methyl Salicylate Glycosides in Some Italian Varietal Wines. | Carlin, S., et al. 2019. Molecules. 24: PMID: 31500198
- Metabolism of airborne methyl salicylate in adjacent plants. | Masimbula, R., et al. 2020. Biosci Biotechnol Biochem. 84: 1780-1787. PMID: 32479137
- Engineered Bacterial Production of Volatile Methyl Salicylate. | Chien, T., et al. 2021. ACS Synth Biol. 10: 204-208. PMID: 33331760
- Understanding Methyl Salicylate Hydrolysis in the Presence of Amino Acids. | Cheng, CY., et al. 2021. J Agric Food Chem. 69: 6013-6021. PMID: 34009964
- Anesthetic Pharmacology of the Mint Extracts L-Carvone and Methyl Salicylate. | Brosnan, RJ., et al. 2022. Pharmacology. 107: 167-178. PMID: 35100605
- Methyl salicylate affects the lipophilic and hydrophilic antioxidant capacities of apricot by regulating carotenoid biosynthesis and phenolic metabolism. | Li, X., et al. 2022. Food Chem. 385: 132709. PMID: 35306237
- The role of methyl salicylate in plant growth under stress conditions. | Gondor, OK., et al. 2022. J Plant Physiol. 277: 153809. PMID: 36099699
- Methyl Salicylate, an Odor-Active Compound in Bordeaux Red Wines Produced without Sulfites Addition. | Pelonnier-Magimel, E., et al. 2022. J Agric Food Chem. 70: 12587-12595. PMID: 36129228
- New trends in methyl salicylate sensing and their implications in agriculture. | Ashrafi, AM., et al. 2023. Biosens Bioelectron. 223: 115008. PMID: 36577177
- On the mechanism of salicylate-induced hypothrombinaemia. | Park, BK. and Leck, JB. 1981. J Pharm Pharmacol. 33: 25-8. PMID: 6114147
- Potential dangers from topical preparations containing methyl salicylate. | Chan, TY. 1996. Hum Exp Toxicol. 15: 747-50. PMID: 8880210
Methyl Salicylate (119-36-8) Modulation Targets
Inhibitor of: LIR-7, ODR-10, Olfr1024, Olfr1040, Olfr1082, Olfr16, Olfr299, Olfr304, Olfr308, Olfr309, Olfr313, Olfr318, Olfr323, Olfr346, Olfr354, Olfr390, Olfr414, Olfr419, Olfr421, Olfr433, Olfr435, Olfr596, Olfr665, OR1A1, OR2T2, OR4Q3, OR5P2, OTTMUSG00000017864, OTTMUSG00000017866, V3R 1, Vmn1r175, and Vmn2r117.Activator of: EG435940, Lipocalin-14, MUP8, Olfr1002, Olfr101, Olfr1013, Olfr1015, Olfr1016, Olfr102, Olfr1020, Olfr1022, Olfr1023, Olfr1026, Olfr1028, Olfr1030, Olfr1031, Olfr1032, Olfr1033, Olfr1034, Olfr1036, Olfr1040, Olfr1043, Olfr1044, Olfr1045, Olfr1047, Olfr1048, Olfr1049, Olfr1051, Olfr1056, Olfr1058, Olfr1062, Olfr1065, Olfr1066, Olfr1082, Olfr1084, Olfr1087, Olfr1097, Olfr1101, Olfr1106, Olfr1107, Olfr1109, Olfr1178, Olfr1253, Olfr1426, Olfr151, Olfr208, Olfr224, Olfr265, Olfr30, Olfr304, Olfr307, Olfr308, Olfr309, Olfr31, Olfr310, Olfr311, Olfr312, Olfr313, Olfr314, Olfr316, Olfr317, Olfr319, Olfr320, Olfr33, Olfr330, Olfr331, Olfr332, Olfr338, Olfr339, Olfr340, Olfr341, Olfr342, Olfr344, Olfr345, Olfr346, Olfr347, Olfr350, Olfr351, Olfr352, Olfr353, Olfr354, Olfr355, Olfr356, Olfr357, Olfr358, Olfr360, Olfr361, Olfr371, Olfr372, Olfr376, Olfr378, Olfr38, Olfr380, Olfr381, Olfr382, Olfr385, Olfr386, Olfr397, Olfr399, Olfr401, Olfr402, Olfr410, Olfr412, Olfr414, Olfr424, Olfr426, Olfr435, Olfr447, Olfr448, Olfr449, Olfr45, Olfr450, Olfr452, Olfr453, Olfr455, Olfr459, Olfr46, Olfr472, Olfr480, Olfr481, Olfr485, Olfr491, Olfr493, Olfr497, Olfr5, Olfr508, Olfr509, Olfr519, Olfr520, Olfr539, Olfr541, Olfr543, Olfr55, Olfr551, Olfr553, Olfr556, Olfr557, Olfr559, Olfr56, Olfr560, Olfr561, Olfr564, Olfr572, Olfr578, Olfr58, Olfr589, Olfr591, Olfr592, Olfr593, Olfr594, Olfr596, Olfr597, Olfr598, Olfr599, Olfr6, Olfr60, Olfr600, Olfr601, Olfr604, Olfr605, Olfr607, Olfr61, Olfr611, Olfr612, Olfr618, Olfr624, Olfr627, Olfr629, Olfr63, Olfr630, Olfr631, Olfr632, Olfr633, Olfr635, Olfr638, Olfr639, Olfr64, Olfr646, Olfr651, Olfr653, Olfr654, Olfr657, Olfr659, Olfr66, Olfr661, Olfr663, Olfr666, Olfr667, Olfr668, Olfr671, Olfr672, Olfr679, Olfr68, Olfr681, Olfr685, Olfr686, Olfr687, Olfr688, Olfr689, Olfr69, Olfr690, Olfr691, Olfr698, Olfr699, Olfr70, Olfr703, Olfr704, Olfr71, Olfr722, Olfr724, Olfr728, Olfr729, Olfr730, Olfr735, Olfr736, Olfr738, Olfr74, Olfr742, Olfr747, Olfr749, Olfr76, Olfr761, Olfr765, Olfr768, Olfr769, Olfr771, Olfr828, Olfr830, Olfr835, Olfr836, Olfr851, Olfr853, Olfr854, Olfr855, Olfr857, Olfr859, Olfr862, Olfr874, Olfr875, Olfr876, Olfr878, Olfr895, Olfr898, Olfr902, Olfr909, Olfr913, Olfr917, Olfr918, Olfr934, Olfr938, Olfr954, Olfr968, Olfr969, Olfr97, Olfr970, Olfr971, Olfr972, Olfr985, Olfr987, OR10A3, OR10A4, OR10A6, OR10A7, OR10AG1, OR10C1, OR10G2, OR10G8, OR10H1, OR10H2, OR10H4, OR10H5, OR10V1, OR10X1, OR11A1, OR13J1, OR1I1, OR1S1, OR1S2, OR2AG1, OR2B6, OR2D3, OR2F2, OR2H2, OR2J3, OR2M4, OR2T2, OR2T35, OR2Y1, OR4A47, OR4A5, OR4B1, OR4C15, OR4D10, OR4D11, OR4D5, OR51B2, OR51B4, OR51B5, OR51B6, OR51D1, OR51F1, OR51F2_Olfr568, OR51H1, OR51I1, OR51I2, OR51Q1, OR51S1, OR51T1, OR51V1, OR52A1, OR52B6, OR52D1, OR52E2, OR52E4, OR52E5, OR52E8, OR52I1, OR52I2, OR52J3, OR52K1, OR52K2, OR52L1, OR52M1, OR52N1, OR52N4, OR52N5, OR52W1, OR56A5, OR56B199, OR56B4, OR5A2, OR5AK2, OR5B17, OR5B2, OR5BF1, OR5D13, OR5D18, OR5I1, OR5J2, OR5M10, OR5M11, OR5M3, OR5M8, OR5P2, OR5P3, OR5T1, OR5T2, OR5T3, OR5U1, OR5W2, OR6B3, OR6Q1, OR6T1, OR6X1, OR7A5, OR7C1, OR7C2, OR7D2, OR8B2, OR8B4, OR8B8, OR8D1, OR8G1, OR8G2, OR8H1, OR8I2, OR8J1, OR8K3, OR9A2, OR9G9, OR9I1, OR9Q1, OTTMUSG00000008445, OTTMUSG00000008908, OTTMUSG00000008910, OTTMUSG00000008911, OTTMUSG00000008953, OTTMUSG00000009332, OTTMUSG00000014164, Skint1, Skint5, Skint6, V1RA7, V1RA9, V1rc1, V1RC21, Vmn1r101, Vmn1r122, Vmn1r15, Vmn1r151, Vmn1r17, Vmn1r20, Vmn1r204, Vmn1r209, Vmn1r57, and Vmn2r1.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl Salicylate, 250 ml | sc-204802 | 250 ml | $46.00 | |||
Methyl Salicylate, 500 ml | sc-204802A | 500 ml | $69.00 |