Diagnostic Test in Hematology

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HEMATOLOGIC

DISORDERS:
DIAGNOSTIC
BY: JOHN ARBIE T. TATTAO, RN
I. LABORATORY TESTS
A.Blood Examinations (CBC)
Ø Used to monitor a patient’s
progress response to treatment
Ø Most common laboratory test:
Hgb and Hct levels
4.Hgb test : measures the amount
of Hgb in the peripheral blood by
weight
Hct test : measures the ratio of
2. RBC Indices
b.Mean Corpuscular Volume (MCV)
– N: 80 – 95%
Formula: Hct/RBC
b. Mean Corpuscular Hgb(MCH)
N: 27 – 32%
Mean Corpuscular Hgb Conc.
(MCHC) – N: 32 – 36%
Formula: MCH: Hgb/RBC
MCHC: Hgb/Hct
3. Reticulocyte Count – measures
the number of immature RBC’s
circulating in the blood
- Provides useful info.
about the erythropoietic activity
of the bone marrow
4. Differential WBC Count
5. Platelet Count
6. RBC Count
Laboratory Test of Blood
Cells
I. LABORATORY TESTS
B. PERIPHERAL BLOOD SMEAR
ØIdentifies the color, size, shape
and contents of RBC
1. Color: (Normochromic,
Hypochromic)
2. Anisocytosis: (Normocytic,
Microcytic, Macrocytic)
3. Poikilocytosis: (Leptocytes,
Spherocytes)
I. LABORATORY TESTS
C. Coagulation Studies
1. aPTT : N: 25 – 35 seconds
ØMeasure the number of seconds
in which a clot forms
2. PT: N: 10 – 13 seconds
ØAlso measures the time needed
to form a clot, but specifically
measures clotting factors (I, II,
II. RADIOLOGIC TEST
A. Lymphangiography
Ø A radologic technique used for
visualization of the lymphatic system
flow and nodes to detect the
presence or stage of disease
Ø Radiologist makes a small incision
between the toes or fingers and
instills dye. An iodine-based dye is
injected and rediographs are taken
then and again after 24 and 48 hrs
Lymphangiography
Nursing Responsibility:
Pre-procedure:
1. Obtain informed consent
2. Assess pt. For allergy to
iodine
3. Local anaesthesia is used
before the needle insertion
Lymphangiography
4. Inform patient that he may
experience a sensation of
warmth and flushing as the
iodine based dye is injected
5. The examiner may ask the
patient to walk
Post Procedure:
1. Elevate affected limb for 24
Lymphangiography
2. Assess pt. For signs of
bleeding/adverse reaction
to the dye
3. Assess the affected
extremity for any change
in sensorimotor function
III. BONE MARROW
EXAMINATION
Purposes:
2.To evaluate abnormal blood
cells
3.Monitor the effects of bone
marrow depressants
4.Monitor the patient’s response
to treatment
5.Help diagnose disorders
III. BONE MARROW
EXAMINATION
1.Bone Marrow Aspiration
Ø Most common procedure for
obtaining a bone marrow
sample
Ø √Most common site for BMA:
Ø Other site: sternum,
anterior/posterior iliac spines
III. BONE MARROW
EXAMINATION
Indication of BMA:
ØSevere anemia
ØThrombocytopenia
ØAcute leukemia
ØNeutropenia
III. BONE MARROW
EXAMINATION
2. Bone Marrow Biopsy
ØIndicated when a large
sample of bone marrow is
needed
Ø√Most common site of
BMB
ØOther site: sternum,
III. BONE MARROW
EXAMINATION
Indication of BMB:
ØPancytopenia
ØLymphoma
ØMyelofibrosis
ØMetastatic tumor
ØMutliple myeloma
Nursing Responsibility
Pre-procedure:
2.Education, preparation, and
emotional support of the patient
before bone marrow aspiration
3.Remind the pt. to lie still during
the entire procedure
Post-procedure:
1. Apply pressure dressing over the
aspiration site
Nursing Responsibility
2. Advise patient to lie on
the biopsied side.
3. Monitor the site every
15 minutes.
4. An ice bag maybe
applied to the site

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