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    C FistulaTable I

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    linubinoi
    An experiment tested the effects of MEC (a compound) on skin carcinogenesis induced by DMBA and croton oil in mice. Mice were divided into groups: an untreated control group, a group receiving MEC during promotion only, and a group receiving MEC during initiation and promotion. The group receiving MEC during both stages had significantly fewer total and average papillomas compared to the untreated group at 12 and 15 weeks. They also had higher survival rates at 15 weeks.

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    C FistulaTable I

    Uploaded by

    linubinoi
    36 views1 page
    An experiment tested the effects of MEC (a compound) on skin carcinogenesis induced by DMBA and croton oil in mice. Mice were divided into groups: an untreated control group, a group receiving MEC during promotion only, and a group receiving MEC during initiation and promotion. The group receiving MEC during both stages had significantly fewer total and average papillomas compared to the untreated group at 12 and 15 weeks. They also had higher survival rates at 15 weeks.

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    An experiment tested the effects of MEC (a compound) on skin carcinogenesis induced by DMBA and croton oil in mice. Mice were divided into groups: an untreated control group, a group receiving MEC during promotion only, and a group receiving MEC during initiation and promotion. The group receiving MEC during both stages had significantly fewer total and average papillomas compared to the untreated group at 12 and 15 weeks. They also had higher survival rates at 15 weeks.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    36 views1 page

    C FistulaTable I

    Uploaded by

    linubinoi
    An experiment tested the effects of MEC (a compound) on skin carcinogenesis induced by DMBA and croton oil in mice. Mice were divided into groups: an untreated control group, a group receiving MEC during promotion only, and a group receiving MEC during initiation and promotion. The group receiving MEC during both stages had significantly fewer total and average papillomas compared to the untreated group at 12 and 15 weeks. They also had higher survival rates at 15 weeks.

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    Table I Effect of MEC on DMBA and croton oil induced two-stage murine skin carcinogenesis.

    Total and Average no. of papillomas Quantal 15 week survival Latency 8 week total G1 G2 Untreated control Receiving MEC @ 100mg 1kg body wt thrice weekly (promotional stage) on 1st and 3rd week of the experiment Receiving MEC @ 100mg 1kg body wt G3 throughout the study period thrice weekly (Both pre initiational and promotional stage) **significantly different from G1 at P<0.01 n=10 10/10 0 0** 2 0.20.01 * 5 0.50.17`** 12 week 30% 10/10 0 0** 9 9/10 8 average 0.90.07
    th

    Groups

    Treatment

    12 week total 27 average 2.70.6 0.70.06 * total 31 8

    th

    15 week average 3.10.62 0.80.09**

    th

    period

    Animals with papilloma on week 15 80% 50%

    8 week 9 week

    * significantly different from G1 at P<0.05

    n=10

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