This document discusses the pathophysiology of sepsis. It outlines the risk factors, stages of infection from systemic inflammatory response syndrome to septic shock, and multiple organ dysfunction syndrome. It then provides a diagram showing the septic process, from the focus of infection to death, involving the release of primary and secondary mediators that can lead to shock and multiple organ dysfunction.
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This document discusses the pathophysiology of sepsis. It outlines the risk factors, stages of infection from systemic inflammatory response syndrome to septic shock, and multiple organ dysfunction syndrome. It then provides a diagram showing the septic process, from the focus of infection to death, involving the release of primary and secondary mediators that can lead to shock and multiple organ dysfunction.
This document discusses the pathophysiology of sepsis. It outlines the risk factors, stages of infection from systemic inflammatory response syndrome to septic shock, and multiple organ dysfunction syndrome. It then provides a diagram showing the septic process, from the focus of infection to death, involving the release of primary and secondary mediators that can lead to shock and multiple organ dysfunction.
Copyright:
Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online from Scribd
This document discusses the pathophysiology of sepsis. It outlines the risk factors, stages of infection from systemic inflammatory response syndrome to septic shock, and multiple organ dysfunction syndrome. It then provides a diagram showing the septic process, from the focus of infection to death, involving the release of primary and secondary mediators that can lead to shock and multiple organ dysfunction.
Copyright:
Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online from Scribd
Response to a wide variety or clinical insults: -hyperthermia -tachycardia -tachypnea -increased WBC
Sepsis SIRS with hypotension in response to infection
Severe Sepsis Sepsis with organ dysfunction, hypoperfusion or hypotension. May include change in mental status, oliguria, hypoxemia, or lactic acidosis.
Septic Shock Severe sepsis with persistent hypotension despite adequate fluid resuscitation
Multiple Organ Dysfunction Syndrome
Presence of altered organ function such that homeostasis cannot be maintained without intervention. The Septic Process
