Scribd Logo
Upload

Welcome to Scribd!

  • 110 views

    Molar Pregnancy

    Uploaded by

    fardeal_mckk
    Gestational trophoblastic disease includes molar pregnancy, choriocarcinoma, and placental-site trophoblastic tumor. A molar pregnancy can be either a complete mole, where an empty egg is fertilized by one sperm containing only paternal chromosomes, or an incomplete mole, where an egg is fertilized by two sperm containing both paternal and maternal chromosomes. Risk factors for molar pregnancy include age extremes and lower socioeconomic status. Symptoms include abnormal bleeding, lower abdominal pain, and hyperemesis gravidarum. Diagnosis is made through ultrasound showing a snowstorm-like appearance without a fetus and beta hCG levels higher than normal pregnancy. Treatment involves uterine evacuation followed by hCG monitoring and chemotherapy

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd

    Molar Pregnancy

    Uploaded by

    fardeal_mckk
    110 views14 pages
    Gestational trophoblastic disease includes molar pregnancy, choriocarcinoma, and placental-site trophoblastic tumor. A molar pregnancy can be either a complete mole, where an empty egg is fertilized by one sperm containing only paternal chromosomes, or an incomplete mole, where an egg is fertilized by two sperm containing both paternal and maternal chromosomes. Risk factors for molar pregnancy include age extremes and lower socioeconomic status. Symptoms include abnormal bleeding, lower abdominal pain, and hyperemesis gravidarum. Diagnosis is made through ultrasound showing a snowstorm-like appearance without a fetus and beta hCG levels higher than normal pregnancy. Treatment involves uterine evacuation followed by hCG monitoring and chemotherapy

    Original Description:

    ppt

    Copyright

    © © All Rights Reserved

    Available Formats

    PPT, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Gestational trophoblastic disease includes molar pregnancy, choriocarcinoma, and placental-site trophoblastic tumor. A molar pregnancy can be either a complete mole, where an empty egg is fertilized by one sperm containing only paternal chromosomes, or an incomplete mole, where an egg is fertilized by two sperm containing both paternal and maternal chromosomes. Risk factors for molar pregnancy include age extremes and lower socioeconomic status. Symptoms include abnormal bleeding, lower abdominal pain, and hyperemesis gravidarum. Diagnosis is made through ultrasound showing a snowstorm-like appearance without a fetus and beta hCG levels higher than normal pregnancy. Treatment involves uterine evacuation followed by hCG monitoring and chemotherapy

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    110 views14 pages

    Molar Pregnancy

    Uploaded by

    fardeal_mckk
    Gestational trophoblastic disease includes molar pregnancy, choriocarcinoma, and placental-site trophoblastic tumor. A molar pregnancy can be either a complete mole, where an empty egg is fertilized by one sperm containing only paternal chromosomes, or an incomplete mole, where an egg is fertilized by two sperm containing both paternal and maternal chromosomes. Risk factors for molar pregnancy include age extremes and lower socioeconomic status. Symptoms include abnormal bleeding, lower abdominal pain, and hyperemesis gravidarum. Diagnosis is made through ultrasound showing a snowstorm-like appearance without a fetus and beta hCG levels higher than normal pregnancy. Treatment involves uterine evacuation followed by hCG monitoring and chemotherapy

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    of 14

    Hydatidiform

    Mole
    Gestational Trophoblastic Disease
    Molar pregnancy
    -Complete hydatiditform mole
    -Incomplete hydatiditform mole
    Choriocarcinoma
    Placental-site trophoblastic tumor

    Molar Pregnancy
    Complete mole
    Fertilization an empty egg
    by one sperm.
    All placental villa swollen.
    Fetus, cord, amniotic
    membrane are absent.
    Paternal chromosomes only
    46 XX
    Diploidy
    Incomplete mole
    Fertilization of an egg by
    two sperms
    Some placental villa swollen
    Fetus, cord, amniotic
    membrane are present
    Paternal and maternal
    69XXY
    Triploid
    Molar Pregnancy
    Incidence and epidemiology:
    -In USA 1:1000
    -In Asia 8:1000
    Risk factors for molar pregnancy:
    -Extreme of age
    -Lower socioeconomic status
    -Race and ethnic origin
    -Blacks have lower incidence
    Molar Pregnancy
    Symptoms and signs of molar pregnancy
    -Abnormal bleeding in early pregnancy
    -Lower abdominal pain
    -Toxemia before 24 weeks of gestation
    -Hyperemesis gravidarum
    Molar Pregnancy
    -Uterus large for dates
    -No fetal heart rate
    -Enlargement of the ovaries
    -Hyperthyroidism
    -Expulsion of swollen villi
    Molar Pregnancy
    Diagnosis:
    -Ultrasound shows snowstorm-like appearance, no
    fetus, theca lutein cyst
    -Beta hCG in normal pregnancy the level is at it peak at
    around 14 weeks (100,000 mIU/ml)
    TORONTO, CANADA, 1998, SANT.JOS. HOS.
    Management
    Once the diagnosis is made evacuation of
    the uterus should be done but prior to that:
    1. hCG preevacuation.
    2. Chest x-ray.
    3. Correct: anemia, toxemia, hyperthyroidism,
    pulmonary compromise.
    Follow up
    HCG weekly until normal for two values then
    monthly for one year.
    Repeat x- ray if HCG rises or plateau.
    Contraception for one year.
    Pelvic examination every 3 weeks for 3
    months.

    Follow up
    Initiate chemotherapy if:
    1. HCG level is increasing or plateaus
    2. Metastasis disease is present
    3. HCG level is still elevated after 6 months of
    evacuation
    4. HCG starts to rise after being undetectable

    You might also like