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Psychopharm Pocketmod

This document provides a summary of various psychopharmacological treatments organized by drug class. It lists first and second generation antipsychotics, their side effects like extrapyramidal symptoms, weight gain, and QT prolongation. It also lists SSRIs, SNRIs, their side effects and drug interactions. Other classes mentioned include atypical antidepressants, TCAs, MAOIs, benzodiazepines for anxiety and their characteristics like duration of action. Lastly it lists mood stabilizers like lithium, lamotrigine, carbamazepine and their potential side effects.

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luming7
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© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
58 views

Psychopharm Pocketmod

This document provides a summary of various psychopharmacological treatments organized by drug class. It lists first and second generation antipsychotics, their side effects like extrapyramidal symptoms, weight gain, and QT prolongation. It also lists SSRIs, SNRIs, their side effects and drug interactions. Other classes mentioned include atypical antidepressants, TCAs, MAOIs, benzodiazepines for anxiety and their characteristics like duration of action. Lastly it lists mood stabilizers like lithium, lamotrigine, carbamazepine and their potential side effects.

Uploaded by

luming7
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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P s y c h o p h a r m a c o l o g i c T x

A P o n g P o c k e t M o d

A n t i p s y c h o t i c
1
s t
g e n
2
n d
g e n
S S R I s
S N R I s
a t y p i c a l s
T C A s
B e n z o s
M o o d
s t a b i l i z e r s

- a z i n e , - a p i n e , - d o l , - d o n e




- o x e t i n e , - l i n e , - o p r a m
- p i o n , - f a x i n e , - z a p i n e , - t i l i n e ,
- o d o n e

- p r a m i n e , - p t y l i n e

- o l a m , - z e p a m , - p o x i d e

- z e p i n e , - t r i g i n e , - i u m ,
- p r o e x
- a p i n e , - d o n e
Antipsychotics
1
st
gen --| D
2
rec
Hi potency
o Haloperidol
o Fluphenazine
o Pimozide
Low potency
o Chlorpromazine
o Thioridazine
2
nd
generation
Atypical for OLdCLOZetsto QUET
RISPERing, so ZIP it, ARI!. CO/RQ/AZ
Clozapine
Olanzapine
Risperidone
Quetiapine
Aripiprazole
Ziprazidone

QTint lead II/longest >500ms, 460 caution
Haloperidol
Olanzapine
Risperidone**
Quetiapine
Ziprazidone
Thioridazine**
EPS
4
o
AD
4d akinesia/parkinsonianism
4wk akathisia (tx: BB, BZD)
4mo TD
NMS (tx: Dantro, Bromocrip,
Amant, BZD)
--------------------------
low E
Weight gain
Sleepiness
Drooling
Cholinergic fx
Cork-az



Fattygenic
Increased risk of metabolic
syndrome, DM
QT prolongation
Increased risk torsades de
pointes
SSRIs
5-HT reuptakeinhibition
CYT 2D6 inhibition
Fluoxetine, sertraline, paroxetine, citalopram

SNRIs
5-HT/NE reuptakeinhibition
Venlafaxine, (desvenla), Duloxetine, (Tramadol)

ADRs
GI distress
Sexual dysfunction (tx: buproprion, yohimbine,
cyproheptadine, sildenafil)
Serotonin syndrome
o Hyperthermia
o Musclerigidity/myoclonus
o CV collapse
Liver damage(Atomoxetine: ADHD tx)
CYT2D6 inhibition (fluox, parox, buprop)
o IncreasesTCA andantipsychotic levels
Withdrawal syndrome: flu-like sx: handjoint
GI (fluvoxetine, paroxetine, citalopram,
sertraline, fluoxetine)
Atypical antidepressants
it takes BUtanein the VEiNs to MIRdir
for aMAP of alcaTRAZ.
Buproprion - smoking, NE/DA RI
o ADR: HTN & seizure
o cautioninbulimia/PHx seizure
Venlafaxine- GAD, 5HT/NE/DA RI
o ADR: HTN
Mirtazepine- atypical depression, 2 blocker
Maprotiline- NE RI, sedation/sz
Trazodone- SSRI, sedn/priapism/ortho hypoTN

TCAs
Imipramine, amitryptyline, desipramine,
nortriptyline, clomipramine, doxepin, amoxepin
ADRs
Sedation, -blockade, anticholinergic effects
convulsions, coma, cardiotoxicity (tx w/
NaHCO3), confusion/hallucinationinelderly

MAOi
Phenylzine, tranylcypromine
Atypical depression
HTN crisisw/ tyramine-containingfoods
(fermented/pickled), no SSRIsor -ag
Benzodiazepines
GABA
A
enhancer
Ultra-/Short: TOMA
o Triazolam(<5h)
o Oxazepam(4-15h)
o Midazolam(<5h)
o Alprazolam(6-20h)
Med: LET
o Lorazepam(10-20h)
o Estazolam(10-30h)
o Temazepam(8-22h)
Long: CDC
o Chlordiazepoxide(5-30h)
o Diazepam(20-100h)
o Clonazepam(18-50h)
Extrahepatic: CLOT the cirrhotics
Clonazepam
Lorazepam
Oxazepam
Temazepam

OD tx: Flumazenil
0.2mgIV x1 30sec
0.3mgIV x1 30sec
0.5mgIV Qmin
max 3mg
TOMA, LET CDC handle benzos
M o o d s t a b i l i z e r s
C a r b e m a z e p i n e
L a m o t r i g i n e
L i t h i u m : L M N O P
o M o v e m e n t d i s o r d e r s
o N D I
o h y p O t h y r o i d i s m
o P r e g n a n c y P r o b l e m
E b s t e i n s a n o m a l y
( R V & t r i c u s p i d p r o b l e m s )
V a l p r o i c a c i d / D i v a l p r o e x
Q u e t i a p i n e , Z i p r a z i d o n e , O l a n z a p i n e

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