Red Eye-Dr S Brodovsky

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Not "THE RED EYE" Again!

Stephen Brodovsky MD, FRCSC Associate Professor Dept of Ophthalmology University of Manitoba Private Practice Cataract/Corneal/Refractive Surgery

Ocular History & Examination


Visual Acuity Pupils Motility Anterior segment (cornea & conjunctiva) Posterior segment Confrontation Fields Intraocular Pressure

Usual RED EYE Lecture


INFECTIOUS: VIRAL vs BACTERIAL ALLERGIC DRY EYE TOXIC SUBCONJUNCTIVAL HEMORRHAGE IRITIS EPISCLERITIS ACUTE ANGLE CLOSURE GLAUCOMA

Photophobia

? Pupil Size ? Location of Injection

What is your provisional Diagnosis ?

Iritis

If painful, usually not pink eye


Differential Diagnosis Includes: Corneal Abrasion Bacterial or Herpetic Corneal Ulcer Episcleritis or Scleritis Acute Angle Closure Glaucoma

Keratic Precipitates

Keratic Precipitates

Iritis Treatment
Topical Steroid drops (up to q1h) and
cycloplegic drop eg Homatropine 2% Ophthalmic referral Steroid & cycloplegic drops are tapered over 1 month Check intraocular pressure If recurrent consider medical workup

Why is the patient having difficulty working ?


Cycloplegic drops interfere with near
vision Important to prevent posterior synechiae (adhesions of iris to lens)

Photophobia &/or Ciliary Injection


Indicates corneal
and/or anterior chamber inflammation Always rule-out corneal staining defect with fluorescein eg abrasion, herpes dendrite, corneal ulcer

Photophobia & Ciliary Injection


Corneal Abrasion Corneal Ulcer Herpes Simplex

Corneal Ulcers: Rosacea & Blepharitis

Contact lens wearer & corneal ulcer

ALWAYS ASK ABOUT CONTACT LENS WEAR!!!

Chronic Irritation

What is your provisional Diagnosis ?


Dry Eye

History

Ask about: Dry mouth (Sjogrens syndrome) Connective tissue disease Systemic medication that may contribute to dry eye symptoms

Dry Eyes

Common ocular condition Incidence increases with age History is the most important clue to Dx Treatment may be initiated by family doctor Ophthalmic consultation in refractory situations

Keratitis in Advanced Dry Eye

Schirmer Test

Tear production measured

Rule-out Blepharitis
Erythema of lid margin Scales on Lashes Loss of Cilia

Frequently co-exists with dry eye

Dry Eye Treatment


Artificial tears up to 1 drop qid (consider
cooling drops) Ointment at bedtime Humidifier Preservative free tears up to q1h Punctal occlusion (silicone plugs) or cautery Oral pilocarpine (Salogen) Restasis (topical cyclosporin: only available thru HPB)

Acute Red Eye

Red Eye

No change in vision No photophobia No pain No staining of cornea

What is your provisional Diagnosis ?


Sub-conjunctival hemorrhage

Provisional Diagnosis
Subconjunctival hemorrhage

? Trauma ? Valsalva Maneuver

? Elevated BP ? Blood Clotting

Subconjunctival Hemorrhage Management


Reassure patient that blood will reabsorb Referral not necessary Clotting status to be evaluated to make sure
Coumadin dosage satisfactory Be sure that BP is OK

Red Eye with Discharge

What is your provisional Diagnosis ?


Bacterial Conjunctivitis

Clinical Pearls
Most cases of infection are secondary
to virus (tearing, enlarged preauricular lymph node) If need fingers to open lids in am this is suggestive of bacterial conjunctivitis Be suspicious of unilateral red eye Trichiasis ? Foreign Body ? Dacryocystitis ?

Differential Diagnosis

Lacrimal System Obstruction

Bacterial Conjunctivitis Treatment


Broad-spectrum fluoroquinolone antibiotic
is effective for suspected bacterial case 1 drop qid for 7 to 10 days Warm compresses to clean lids of discharge Cultures usually not required unless recurrent or persistent Ciprofloxacin or Erythromycin available as an ointment for children

Bacterial Conjunctivitis Treatment


Lancet. 2005 Jul 2-8:366(9479):37-43 Chloramphenicol treatment for acute
infective conjunctivitis in children in primary care: a randomised double-blind placebo controlled trial Rose PW et al, Oxford UK Placebo vs Chloramphenicol gtts 83% vs 86% cure rates at 7 days

Bacterial Conjunctivitis Treatment


Conclusion: Most children with acute infective conjunctivitis will get better by themselves and do not need treatment with an antibiotic

Chronic Red Eye

Chronic Conjunctivitis
Differential Diagnosis

Allergic or Toxic reaction to eye drops Dry eyes (dryness, irritation, burning) Blepharitis (scales on lashes, erythema of
lid margin) Contact lens wear!!

Diagnosis ?
Chronic Conjunctivitis Secondary to toxic or allergic reaction to topical medication

Management
Alphagan eye drops discontinued Redness resolved in one week Ophthalmologist to start another antiglaucoma medication

Toxic Reaction to Eye Drops


Common scenario is treatment of
conjunctivitis with gentamicin eye drops No improvement after one week, new medication is prescribed Toxic keratopathy results Use antibiotics for 1 week, 1 drop qid -> If no improvement -> Refer

Itching

What is your provisional Diagnosis ?

Allergic Conjunctivitis

Allergy
Allergen IgE

Mast cells
Factors Released: Histamine, Chemotactic factors, Prostaglandin synthesis

Management of Ocular Allergy


Cold compresses Mast cell stabilizer & anti-histamine eg Patanol
or Zaditor bid Systemic antihistamines (Can Have Drying Effect on Eyes Natural DefenderTear Film) Frequent showers to remove allergens from hair, skin, etc. If highly symptomatic referral to ophthalmologist Mild topical steroid (FML) Restasis (topical cyclosporin)

Red Eye Summary


Photophobia Chronic Irritation Acute Red Eye Red Eye with Discharge Chronic Red Eye Itching

Decreased Vision Post-Cataract Surgery

History of Perfect Vision then Unable to Distinguish Material in first week after Surgery

What is your provisional Diagnosis ?

Endophthalmitis

What is your management ?


Referral to ophthalmologist in A. 1 week B. 2 days C. 1 day D. Same day

Complications Post-Cataract Surgery



Endophthalmitis Retinal detachment Macular edema Corneal edema

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