Blood Grouping Reagents

A comprehensive range

2013

Blood Grouping Reagents

The Alpha Laboratories range of Blood Grouping products is one of the most comprehensive available from a single supplier. Whether you require routine or speciality products, a wide range of anti-sera or red cells, or are simply looking for reliable control materials, Alpha can support your blood grouping needs.

Control Reagents ALBAcheck-DUO

Simulated whole blood controls for automated grouping systems. These consistent and affordable simulated whole blood controls from the ALBAcheck range offer ABO and Rh testing for both donors and patients.

n Twice

the stability of standard controls -14 day open vial: Less wastage cell suspension for greater volume of useable sera: More tests for your money of each 6ml vials are supplied: Just one kit needed per month the BCSH and transfusion guidelines on a 4 week cycle for continuity of supply

Contents
Control Reagents

n 15%

n Two

n Meets

- ALBAcheck -DUO Simulated Whole Blood Control 2 - ALBAcheck-BGS Simulated Whole Blood Control - ALBAcheck-BGS Competency Test Kit - ALBAcheck-BGS High Titre Controls Kit - Sensitivity Controls - Other Control Reagents 3 3 3 3 4

n Available

Reagent Red Cells 4 - ALBAcyte 0.8% Reagent Red Cell Panels - ALBAcyte 2-3% Reagent Red Cell Panels 4 4-5

Specialist Blood Grouping Reagents 5 - ALBAclone Monoclonal ABO Antisera - ALBAclone Monoclonal RhD Antisera - ALBAclone Advanced Partial RhD Typing Kit - ALBAclone Rare Monoclonal Antisera - ALBAsera Polyclonal Reagents 5 5 6 6 6
Vial Phenotype Antibody

Vial 1 Vial 2
Catalogue Number

Group A2B rr (ccdee) Group O R1R1 (CCDee)

Description

Anti-D (0.1 IU/ml) Anti-A, Anti-B & Anti-c

Pack Size Price ex .VAT

ALBAcheck-DUO

Z483

ALBAcheck-DUO Whole Blood Control

4 x 6ml

73.82

Alba Bioscience Limited

Anti-Human Globulin 7 Solutions, Lectins, Enzymes & Enhancement Media 7

n freephone order 0800 387732 n buy online at www.alphalabs.co.uk

ALBAcheck-BGS
This comprehensive set provides ultimate control. It gives extra confidence in the correct functioning of your automated blood grouping system and its sensitivity to detect clinically significant antibodies.
n Four

ALBAcheck-BGS High Titre Controls Kit

seller

best

different group format vials cover ABO and Rh/K antigens, plus anti-D and anti-Kell antibodies in 6ml vials of 15% RBC suspension on a 4 weekly cycle subscription product
Antibody

n Supplied

n Manufactured
Vial

Phenotype

Vial 1 Vial 2 Vial 3 Vial 4

Catalogue Number

Group A R1R1, K Pos Group B R1R2, K Neg Group O R2R2, K Neg Group AB rr, K Neg
Description

Anti-B Anti-A and Anti-K Anti-A and Anti-B Anti-D

Pack Size Price ex .VAT

For the control of high titre anti-A and anti-B testing of blood donations. The kit provides a positive and negative control (2 vials each), which should be tested in the same way as the donation test samples.

ALBAcheck-BGS

Z489

ALBAcheck-BGS Whole Blood SP control

4 x 6ml

113.21

Alba Bioscience Limited

In accordance with the Guidelines for Blood Transfusion Services in the United Kingdom 7th Edition, the positive control has a potency of greater than 1/128 and the negative control less than 1/128.
n Unique

product stability: 2 weeks

n Open-vial

ALBAcheck-BGS High Titre Controls Kit

Catalogue Number Description Pack Size Price ex .VAT

Z257

ALBAcheck-BGS High Titre Controls Kit

4 x 6ml

210.80

Alba Bioscience Limited

Sensitivity Controls ALBAcheck -BGS Competency Test Kit

Intended for use as an internal, self assessment QA scheme. It assesses the ability of an individual and/or the capability of a method for detecting weak antibodies.
n Kit

Specially formulated weak sensitivity controls, designed to stress testing platforms.

n Validated n Derived

for use in column technologies

from a pool of donations material which presents as a normal weak sample

n Polyclonal n Different

consists of: l 10 randomly selected serum samples l Results available on-line please enquire store at 2-8 C

specificities demonstrates ability to detect a range of weak antibodies

Description Pack Size Price ex .VAT

n Ready-to-use, n Closed

Sensitivity Controls
Catalogue Number

vial stability: 1 year for use in column technology and tube systems

Z251 Z252 Z253 Z261

Pack Size Price ex .VAT

Anti-D 0.3iu/ml ALBAcheck-BGS Anti-c (weak) ALBAcheck-BGS Anti Fya (weak) Anti-D Controls Kit 0.1, 0.05, 0.025 iu/ml Anti-D Anti-D Control 0.1 iu/ml Anti-D Anti-D Control 0.05 iu/ml Anti-D

10 x 10ml

199.98

n Validated

3 x 5ml 38.71 3 x 5ml 39.35 3 x 5ml 48.14 3 x 5ml 51.66 3 x 5ml 51.66

ALBAcheck-BGS Competency Test Kit

Catalogue Number Description

Z262 Z263

Z276

ALBAcheck-BGS Competency Test Kit

10 x 2ml

212.50

Alba Bioscience Limited

Alba Bioscience Limited

n email order [email protected] n freefax order 0800 614249

Other Control Reagents

A range of control reagents, which enables the user to validate and control testing on an individual or batch basis.
Other Control Reagents
Catalogue Number Description Pack Size Price ex .VAT

ALBAcyte 0.8% ID Panels

n Include

Kpa and Lua positive as well as Fya-b- and Lea-bphenotypes phenotype information available on panel cells

n Extended n Profile

Z256 Z271 Z281

Enzyme Control Reagent Control for Anti-D (Use with Z031, Z036, Z039, Z041) AB Serum (human)

10 x 10ml 206.88 10 x 10ml 91.85

allows identification of most antibodies & mixture without recourse to additional panels and papainised panels are prepared from the same donations to provide complementary results

n Native 10 x 5ml 272.51

Alba Bioscience Limited

Reagent Red Cells ALBAcyte 0.8% Reagent Red Cell Panels

Reagent Red Cell panels are now available in convenient 0.8% ready-to-use cell suspensions. They are ideal for column agglutination technologies and can be used in both patient and donor testing applications. All panels are manufactured from pre-selected donors, providing consistent high quality products.
n n

ALBAcyte 0.8% ID Panels

Catalogue Number Description Pack Size Price ex .VAT

Z458 Z459

Antibody Identification (Native) Antibody Identification (Papainised)

11 x 4 ml 11 x 4 ml

81.10 89.14

Alba Bioscience Limited

No dilution required - convenient and accurate Bar-coded for use on Column Agglutination Testing (CAT) systems e.g. Ortho AutoVue and Bio-Rad (DiaMed) systems CAT READY negative panels for antibody screening in patients who have received prophylactic Anti-D

ALBAcyte 2-3% Control Cells

2-3% Red Cell panels for conventional manual tube and microplate testing. All ALBAcyte red cell reagents comply with UK BTS Guidelines.
n For

n RhD

Cells comply with UK BTS Guidelines

both conventional tube and microplate testing

ALBAcyte 0.8% Reagent Red Cell Panels

Catalogue Number Description Pack Size Price ex .VAT

n Panels

manufactured from pre-selected donors to provide consistent quality with UK BTS Guidelines

Z403

A1 and B Cells

2 x 10ml

18.56

n Comply

Alba Bioscience Limited

n Available

on 4-weekly subscription order to ensure 28-day shelf life on receipt

ALBAcyte 0.8% Screening Panels

Manufactured from frozen, HLA-typed red cells to minimise problems associated with Bg and other HTLA antigens.
ALBAcyte 0.8% Screening Panels
Catalogue Number Description Pack Size Price ex .VAT

ALBAcyte 2-3% Control Cells

Catalogue Number Description Pack Size Recommended Use Price ex .VAT

Z401 Z406 Z411 Z416 Z421 Z427 Z441

A1 Cells A2 Cells B Cells O R1r Cells Orr Cells DVI Cells IgG Sensitised Cells

10ml 10ml 10ml 10ml 10ml 5ml 10ml

Reverse grouping controls Controls Reverse grouping controls Controls Controls Controls Confirmation and controls

6.90 11.67 6.90 7.43 13.67 29.73 10.61

Z455 Z466

Antibody Screen (Native) RhD Negative Antibody Screen (Native)

3 x 10ml 3 x 5ml

38.54 35.14

Alba Bioscience Limited

Alba Bioscience Limited n Wide

range of controls and rare cells available with conventional blood grouping tests

n Ready-for-use

n freephone order 0800 387732 n buy online at www.alphalabs.co.uk

ALBAcyte 2-3% Screening Panels

n Comprised n Prepared

Specialist Blood Grouping Reagents ALBAclone Monoclonal ABO Antisera

A wide range of extensively tested monoclonal ABO grouping antisera.
n Monoclonal

of R1 WR1, R2 R2 and rr red cell phenotypes

from pre-selected and well established donor C positive on all screening panels
W

panels
n Includes n Native

and papainised panels available

ALBAcyte 2-3% Screening Panels

Catalogue Number Description Pack Size Price ex .VAT

antibodies exhibit high degrees of potency, avidity and specificity reagent is dyed blue & Anti-B is dyed yellow

n Anti-A

Z451 Z452

Antibody Screen (Native) Antibody Screen (Papainised)

3 x 10ml 3 x 10ml

27.58 44.56

n Manufactured

and standardised in accordance with UK BTS Guidelines

Alba Bioscience Limited

ALBAcyte 2-3% ID Panels

n Reagent n Extended n Profile

Slide
dropper bottles deliver approximately 40l

phenotyping information available on panel cells

allows identification of most antibodies and mixture without the need for a second panel Kpa and Lua positive on ID panels and papainised panels available

ALBAclone Monoclonal ABO Antisera - Slide

Catalogue Number Description and Specificity Cell Line Volume Comments Price ex. VAT

n Includes n Native

Z001 Z011 Z021

Anti-A Anti-B Anti-A,B

LA2 LB2 LA2, LB2, ES15

10 x 10ml 10 x 10ml 10 x 10ml Does not detect Acquired B Detects Ax Cells

58.74 58.74 77.29

ALBAcyte 2-3% ID Panels

Catalogue Number Description Pack Size Price ex .VAT

Alba Bioscience Limited

Z471 Z472

Antibody Identification (Native) Antibody Identification (Papainised)

10 x 5ml 10 x 5ml

74.26 128.90

Alba Bioscience Limited

ALBAclone Monoclonal RhD Antisera - Tube, Slide

n Manufactured

and standardised in accordance with UK BTS Guidelines

n Slide

n Recommendations

tests are not recommended for detection of weak and partial RhD types

based on UK BTS Guidelines for Compatibility Procedures in Blood Transfusion Laboratories are available control available

n Reagent

ALBAclone Monoclonal RhD Antisera - Tube, Slide

Catalogue Number Description and Specificity Cell Line Volume Comments Price ex. VAT

Z031 Z036 Z039 Z041 Z271

Anti-D alpha (IgM) Anti-D beta (IgM) Anti-D optimum (IgM/lgG) Anti-D blend (IgM/IgG) Reagent Control for Anti-D

LDM1 LDM3 LDM1/ESD1M LDM3/ESD1 Not Applicable

10 X 10ml 10 X 10ml 10 X 10ml 10 X 10ml 10 X 10ml

Does not detect DVI Does not detect DVI Detects most RhD variants by direct tests Detects DVI by IAGT only For use with Z031, Z036, Z039, Z041

112.85 112.85 169.74 134.49 91.85

Alba Bioscience Limited

n email order [email protected] n freefax order 0800 614249

ALBAclone Advanced Partial RhD Typing Kit

ALBAclone Rare Monoclonal Antisera

A wide range of rare monoclonal blood grouping antisera
n Manufactured

and standardised in accordance with the UK BTS Guidelines to give clear and consistent results by conventional blood grouping techniques antibody unless indicated

n Formulated

n IgM

n Range

includes hard-to-locate sera including Anti-k and Anti-Lub

ALBAclone Rare Monoclonal Antisera

The antibodies incorporated into this kit have undergone extensive Identifies evaluation at international Weak D Types workshops and by experts 1 & 2 and throughout Europe and the DMHi US. The kit allows improved identification of partial RhD types, including DOL, DCS, DMH, DHK/DAU-4, and now weak D types 1 and 2 as well as DMHi.
n 12

Catalogue Number

Description

Cell Line

Pack Size

Price ex .VAT

Z063 Z073 Z083 Z094 Z113 Z137 Z162 Z166 Z171 Z176 Z182 Z202 Z212 Z217 Z223 Z244

Anti-C Anti-E Anti-c Anti-e Anti-CDE Anti-k Anti-Jka Anti-Jkb Anti-M Anti-N Anti-S Anti-P1 Anti-Lea Anti-Leb Anti-Lub Anti-H

P3X2551 3G8 DEM1 H48 MS-16, MS-21, MS-63 DCM1,LDM1,DEM1 Lk1 P3HT7 P3.143 LM1 (IgG) LN3 P3S13JS123 (IgG) 650 LEA2 LEB2 LU2 LH1

3 x 5ml 3 x 5ml 3 x 5ml 3 x 5ml 3 x 10ml 2ml 2ml 2ml 5ml 5ml 2ml 5ml 5ml 5ml 2ml 2ml

163.24 109.45 163.24 161.39 154.59 79.24 112.43 112.43 63.38 63.38 122.00 143.22 77.21 77.21 74.94 114.39

antibodies with matched reaction profiles simple method of testing (IAGT) and easy to perform important partial RhD types

n One

n Quick

n Differentiates n Quick,

Alba Bioscience Limited

cost-effective alternative to DNA genotyping

ALBAclone Advanced Partial RhD Typing Kit

Catalogue Number Description Pack Size Price ex .VAT

ALBAsera Polyclonal Reagents

A range of conventional blood grouping sera.
n For

Z293

ALBAclone Advanced Partial RhD Typing Kit

12 x 2ml

485.00

Alba Bioscience Limited

use by IAGT unless otherwise stated antisera derived from donations of human

Supplementary Information Weak D Types 1 and 2

As shown on the Instructions for Use, Weak D of types 1 or 2 may be positive with all anti-D in the kit or show weakened / negative reactions with anti-Ds C and I. Of the remaining antibodies, anti-Ds H and L are more likely than the others to show weakness with weak D types 1 and 2. Weak D type 2 with suppression of D due to Cde in trans is markedly different; this type may be weak or negative with most anti-D in the kit. Anti-D D and K are most likely to be positive, but still weaker than normal RhD positive cells.
Note: most other weak D types will give weak reaction with all anti-D in the kit (weaker than a normal RhD positive cell).

n Polyclonal

antiserum
n Majority

of antiserum exclusive to this range

ALBAsera Polyclonal Reagents

Catalogue Number Description & Specificity Method of Use Pack Size Price ex .VAT

Z102 Z131 Z139 Z151 Z153 Z186 Z191 Z221* Z231

Anti-Cw indirect Anti-K indirect Anti-Kpa indirect Anti-Fya indirect Anti-Fyb indirect Anti-s indirect Anti-Vw indirect Anti-Lua indirect Anti-Wra indirect

Enzyme IAGT IAGT IAGT IAGT IAGT IAGT IAGT IAGT

5ml 3 x 5ml 2ml 3 x 5ml 2ml 2ml 2ml 2ml 2ml

132.61 95.48 99.05 367.29 119.45 152.18 397.71 210.80 111.39

DHMi Recent tests have shown that DHMi samples will react with
all kit components.

Alba Bioscience Limited

* Dependent on availability

n freephone order 0800 387732 n buy online at www.alphalabs.co.uk

Anti-Human Globulin Polyspecific Anti-Human Globulin Reagent

n Prepared

from a blend of rabbit antibodies to human IgG and a murine monoclonal antibody to C3 (3G8) for optimum detection of IgG and complement binding blood group antibodies be used for both direct and indirect antiglobulin tests (NIS, LIS) is dyed green

n Formulated

n Can

n Reagent

Polyspecific Anti-Human Globulin Reagent

Catalogue Number Description Pack Size Price ex .VAT

Z350

Polyspecific AHG

10 x 10ml

85.02

Alba Bioscience Limited

Monospecific Anti-Human IgG

n Prepared

Anti-Human C3
n Prepared

from a blend of rabbit antibodies to human IgG

n Formulated

for optimum detection of IgG for both direct and indirect antiglobulin tests (NIS, LIS)

from a murine monoclonal antibody to C3 (Class IgG) for optimum detection of C3b and/or C3d components of complement on the surface of red blood cells be used for both direct and indirect antiglobulin tests (NIS, LIS) Line 3G8

n Formulated

Monospecific Anti-Human IgG

Catalogue Number Description Pack Size Price ex .VAT

Z356

Monospecific Anti-Human IgG

3 x 10ml

34.48

n Can

Alba Bioscience Limited

n Cell

To find out more about our range of ALBA Bioscience Blood Grouping Products visit www.alphalabs.co.uk

Anti-Human C3
Catalogue Number Description Pack Size Price ex .VAT

Z360

Anti-Human C3

1 x 3ml

30.33

Alba Bioscience Limited

Solutions, Lectins, Enzymes and Enhancement Media

Solutions, Lectins, Enzymes and Enhancement Media
Catalogue Number Description Pack Size Price ex .VAT

Z241 Z256 Z305 Z311 Z316 Z332 Z335 Z337 Z338

Anti-A1 D Enzyme Control BSA 22% 0.5% Bromelin (Frozen) 1% Papain (Frozen) Phosphate Buffer Concentrate LISS Modified Alsevers Solution Modified Alsevers Solution + ATP

3 x 5ml 10 x 10ml 10 x 10ml 10 x 5ml 10 x 5ml 10 x 25ml 1 litre 2 litre 1 litre

37.13 206.88 102.59 190.96 190.96 171.09 44.43 136.52 92.65

Alba Bioscience Limited

n email order [email protected] n freefax order 0800 614249

Alba Bioscience A Pedigree in Blood Grouping Products

Alba Bioscience is a major bio-manufacturing organisation, providing vital products for hospitals, blood services and healthcare companies in over 30 countries. Originating from the Scottish National Blood Transfusion Service, it has been manufacturing blood typing reagents since the early 1940s and has gone from strength to strength. It merged with the Scottish Antibody Production Unit in 1999 and expanded facilities to a 2000m2 site in 2002, before becoming Alba Bioscience in 2005. Alba Bioscience was acquired by Quotient Bioscience Group in 2007. With an advanced, UK based, FDA approved, GMP, manufacturing plant, it progresses development in automated processes and increased capacity through investment in continuous bioreactor systems. Expertise of more than 100 highly trained staff provides an extensive range of monoclonal antibodies alongside access to red cells and plasma. Commitment to quality and technical excellence is evidenced by a range of appropriate accreditation, including CE marking of products. Customers can be assured that high standards and control throughout the manufacturing processes result in quality products, providing quality outcomes for your tests. Alpha Laboratories is proud to be the UK partner for Alba Bioscience, as it has been for over 14 years.

2013

Alpha Laboratories Limited 40 Parham Drive Eastleigh, Hampshire SO50 4NU United Kingdom
Tel: 023 8048 3000 Fax: 023 8064 3701 Email: [email protected] Web: www.alphalabs.co.uk Customer Account Number