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Solu Cortef

Solu-cortef is a corticosteroid used to treat adrenocortical insufficiency, inflammation from certain skin conditions, and as an adjunct treatment for ulcerative colitis. It works by decreasing inflammation through suppression of immune cells and reduction of capillary permeability. Solu-cortef comes as an injection, cream, ointment, aerosol, tablets, and suppositories and requires monitoring for side effects like increased blood sugar, weight gain, and weakness. Special precautions are needed in patients with conditions like infections, osteoporosis, high blood pressure, or diabetes.

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ianecunar
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3K views

Solu Cortef

Solu-cortef is a corticosteroid used to treat adrenocortical insufficiency, inflammation from certain skin conditions, and as an adjunct treatment for ulcerative colitis. It works by decreasing inflammation through suppression of immune cells and reduction of capillary permeability. Solu-cortef comes as an injection, cream, ointment, aerosol, tablets, and suppositories and requires monitoring for side effects like increased blood sugar, weight gain, and weakness. Special precautions are needed in patients with conditions like infections, osteoporosis, high blood pressure, or diabetes.

Uploaded by

ianecunar
Copyright
© Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Brand name: Solu-cortef

Generic name: Hydrocortisone


Indication: management of adrenocortical insufficiency, relief inflammation of
corticosteroid-responsive dermatoses, adjunctive treatment of ulcerative colotis
Drug classification: anti-inflammatory agent, corticosteroid, glucocorticoid
mineralocorticoid
Mechanism of action: decreases inflammation by suppression of migration of
polymorphonuclear leukocytes and reversal of increased capillary permeability
Dosage: Adult 100-500mg IV over a period of 30sec-10min, Children/infant: not
<25mg/day
Special precaution: hyperthyroidism, cirrhosis, nonspecific ulcerative colitis,
hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive
disorders, myasthenia gravis, thrombophlebitis, peptic ulcer, diabetes
Pregnancy risk category: C
Adverse reaction: CNS: insomnia, nervousness GI: increased appetite Derma:
hirsutism Endo: diabetes mellitus Resp: epistaxis other: cataracts, anthralgia
Contraindications: serious infections, except septic shock or tuberculosis meningitis,
hypersensitivity, viral, fungal or tubercular skin lesions
Form: Aerosol 10%, cream 0.5%, injection, suspension 25mg/ml, ointment 0.5%,
suppository 10mg, tablets 10mg
Nursing responsibilities:
 Monitor any sign of anaphylactic reaction
 Assess client’s urine, muscle weakness and wasting, weight

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