MH Guideline For Web v2
MH Guideline For Web v2
MH Guideline For Web v2
Recognition
Immediate
management
Monitoring
& treatment
Give dantrolene
DANTROLENE
TREAT:
Hyperkalaemia: calcium
chloride, glucose/insulin, NaHCO3
Arrhythmias:
magnesium/amiodarone/metoprolol
AVOID calcium channel blockers interaction with dantrolene
Continuous monitoring
Metabolic acidosis: hyperventilate, Core & peripheral temperature
ETCO2
NaHCO3
SpO2
Myoglobinaemia: forced alkaline
ECG
diuresis (mannitol/furosemide +
Invasive blood pressure
NaHCO3); may require renal
CVP
replacement therapy later
Repeated bloods
ABG
DIC: FFP, cryoprecipitiate, platelets
U&Es (potassium)
FBC (haematocrit/platelets)
Check plasma CK as soon as able
Coagulation
Follow-up
The UK MH Investigation Unit, Academic Unit of Anaesthesia, Clinical Sciences Building, Leeds Teaching Hospitals NHS Trust,
Leeds LS9 7TF. Direct line: 0113 206 5270. Fax: 0113 206 4140. Emergency Hotline: 07947 609601 (usually available outside
office hours). Alternatively, contact Prof P Hopkins, Dr E Watkins or Dr P Gupta through hospital switchboard: 0113 243 3144.