F.S. is a 35-year-old female, 5'3" tall and weighing 60 kg, who is being treated for pregnancy-induced hypertension with metoprolol 50mg twice daily. Metoprolol is a beta-1 selective adrenergic blocker used to treat hypertension and prevent heart attacks. It works by blocking beta receptors in the heart and kidneys to lower blood pressure and heart rate. Common side effects include dizziness, fatigue, and shortness of breath. Nurses monitor the patient's vital signs and watch for side effects, instructing the patient to notify the provider if shortness of breath occurs.
F.S. is a 35-year-old female, 5'3" tall and weighing 60 kg, who is being treated for pregnancy-induced hypertension with metoprolol 50mg twice daily. Metoprolol is a beta-1 selective adrenergic blocker used to treat hypertension and prevent heart attacks. It works by blocking beta receptors in the heart and kidneys to lower blood pressure and heart rate. Common side effects include dizziness, fatigue, and shortness of breath. Nurses monitor the patient's vital signs and watch for side effects, instructing the patient to notify the provider if shortness of breath occurs.
F.S. is a 35-year-old female, 5'3" tall and weighing 60 kg, who is being treated for pregnancy-induced hypertension with metoprolol 50mg twice daily. Metoprolol is a beta-1 selective adrenergic blocker used to treat hypertension and prevent heart attacks. It works by blocking beta receptors in the heart and kidneys to lower blood pressure and heart rate. Common side effects include dizziness, fatigue, and shortness of breath. Nurses monitor the patient's vital signs and watch for side effects, instructing the patient to notify the provider if shortness of breath occurs.
F.S. is a 35-year-old female, 5'3" tall and weighing 60 kg, who is being treated for pregnancy-induced hypertension with metoprolol 50mg twice daily. Metoprolol is a beta-1 selective adrenergic blocker used to treat hypertension and prevent heart attacks. It works by blocking beta receptors in the heart and kidneys to lower blood pressure and heart rate. Common side effects include dizziness, fatigue, and shortness of breath. Nurses monitor the patient's vital signs and watch for side effects, instructing the patient to notify the provider if shortness of breath occurs.
Maximum dose: 450 mg PO Minimum Dose: 50 mg PO BID Availability: Tablets 25, 50, 100mg; ER tablets 25, 100, 200mg; injection 1mg/ml
Pregnancy category risk: C
MECHANISM OF ACTION
Competitively blocks beta-adrenergic receptors in the heart and juxtaglomerular apparatus, decreasing the influence of the sympathetic nervous system on these tissues and the excitability of the heart, decreasing cardiac output and the release of renin, and lowering BP; acts in the CNS to reduce sympathetic outflow and vasoconstrictor tone
Onset:15min Route: PO
INDICATIONS
General: > hypertension, along wit other drugs, especially diuretics > prevention of reinfarction of MI patients who are hemodynamically stable or within 310 days of the acute MI > long-term management of angina pectoris > treatment of stable, symptomatic heart failure of ischemic, hypertensive or cardiomyopathic origin
Peak: 90 min Duration: varies Metabolism: hepatic; 3-4 hr Distribution: crosses placenta, enters breast milk
Patients actual indication: Metoprolol is given to patient for the treatment of pregnancyinduced hypertension
Excretion: urine
CONTRAINDICATI ON
ADVERSE EFFECTS
Drug hypersensitivity, sinus bradycardia, greater than first-degree heart block, cardiogenix shock, or overt cardiac failure when used to treat hypertension or angina. When used to treat MI, contraindicated in patients with heart rate of less than 45 bpm, greater than first degree heart block, systolic blood pressure less than 100 mm Hg, or moderate to severe cardiac failure.
Allergic: laryngospasm
Precautions: Patients with heart failure, diabetes, respiratory or hepatic disease
Dermatologic: rash, pruritus, sweating, dry skin
Drug Interactions: Barbiturates, rifampin: Increased metabolism of metroprolol Cardiac glycosides, diltiazem, verapamil: Excessive bradycardia and increased depressant effect on myocardium. Catecholamine-depleting drugs such as H2 antaginists, MAO inhibitors
Before: > Check doctors order. > Review medication record. > Record VS, esp. BP and HR > Note for dizziness, fatigue, dyspnea. > Determine hypersensitivity. During: > Introduce self to client. > Confirm clients identity. > Read drug label. > Inform drugs therapeutic effect. > Inform of side effects After: > Evaluate therapeutic response. > Watch for adverse effects. > Tell patient to inform prescriber if shortness of breath occurs. > Inform patient that use of metroprolol isnt advised in breastfeeding women. > document and record
