H.Rosa Sinensis
H.Rosa Sinensis
H.Rosa Sinensis
Pekamwar et al.
Review Article
Article Received on
03 September 2013,
Revised on 27 October 2013,
Accepted on 14 November
2013
ABSTRACT
Nature has been a source of medicinal agents for thousands of year and
a large number of drugs have been isolated from natural sources.
Higher plants, as source of medicinal compounds, have continued to
play an important role in the maintenance of human health since
*Correspondence for
ancient times. Over 50% of all modern clinical drugs are of natural
product origin and have significant role in drug development programs
Author:
KEYWORDS:
Hibiscus
rosa-sinensis,
phytochemistry,
pharmacology.
INTRODUCTION
Nature has been a source of medicinal agents for thoughts of years and a remarkable number
of drugs have been isolated from natural source. Over the years, WHO advocated traditional
medicines as safe remedies for aliments of both microbial and non-microbial origins.
[1]
World Health Organization has recommended that traditional health and folk medicine
systems are proved to be more efficient in health problems worldwide. India is one of the
nations blessed with a rich heritage of traditional medical systems and rich biodiversity to
complement the herbal needs of the treatment administered by these conventional medical
systems. The accepted Indian systems of medicine are Ayurveda, Unani and Siddha, which
uses herbs and natural resources in the formulations. [2]
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Pekamwar et al.
Hibiscus rosa sinensis L (Malvaceae) is an ornamental plant often a hedge or fence plant. It is
native to china and is also seen in India and Philippines. This plant having several forms and
varying colors of flowers. This is a national flower of Malaysia. [3]
Plantae
Subkingdom
Tracheobionta
Super division
Spermatophyta
Division
Magnoliophyta
Class
Magnoliopsida
Subclass
Dilleniidae
Order
Malvales
Family
Malvaceae
Genus
Hibiscus
Species
Hibiscus rosa-sinensis
PHYTOCHEMICAL REVIEW
Different extract of Hibiscus rosa-sinensis plant revealed the presence of alkaloids,
glycosides, fatty materials, reducing sugars, resin, sterols and the lack of tannins and
Saponins. Isolation of -sitosterol, taraxeryl acetate and four uncharacterized compounds
which included an alkaloid and three sterols has been reported in the leaves. The leaves of
Hibiscus rosa-sinensis were also investigated for their fatty alcohol, fatty acids and
hydrocarbon content. Two cyclic acids viz., malvalic and sterculic are also identified. [2]
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Pekamwar et al.
Flowers contain vitamins, flavonoids, ascorbic acid, niacin, riboflavin, thiamine and
cyaniding diglucoside. Quercetin-3-diglucoside, cyanidin-3-sophoroside-5-glycosides, 3, 7diglucoside, cyanidin-3, 5-diglucoside have been isolated from deep yellow flowers. [4]
Table 1: Phytochemical Review
Sr.no. Plant part
1
Flowers[5]
Constituent reported
Thiamine, Riboflavin, Niacin and Ascorbic acid, Apigenidin,
citric acid, fructose, glucose, oxalic acid, pelargonidin, quercetin.
Leaves[2]
Stems[6]
Roots[7]
PHARMACOLOGICAL REVIEW
Hibiscus rosa sinensis (Malvaceae) is a perennial ornamental shrub available throughout
India. Various parts of this plant like flowers, leaves and roots have been known to possess
medicinal properties like oral contraceptive, laxative, aphrodisiac, menorrhagic etc. [8]
Several articles and ancient literature have shown that the flowers of this plant possess
antifertility activity. [9] The aqueous ethanolic extract of aerial parts of this plant was reported
for its use in constipation and diarrhea. [10] In traditional medicine, the leaves of the plant are
used in fatigue and skin disease. Powdered root of the plant is given for menorrhagia and the
fresh root juice for gonorrhea.
[11]
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Pekamwar et al.
It has been reported that the plant flower possess anti-spermatogenic and androgenic [17] antitumour activity. [18] The use of flower to treat heart disorders and anti-diabetic activity has
also been confirmed. [19, 20]
Table 2: Pharmacological Review
Sr
Plant part
Activity reported
Model used
Remark
Flower
Antidiabetic Activity
Steptozotocin
Found to be active
no
1
induced[21]
Alloxan induced[22]
Hair growth potential
Found to be active
Anticonvulsive
Mice[24]
Activity
Antifertility Activity
[25]
Rats
Antifertility
effects
in rats
Abortifacient
Rats[26]
A dose of 186mg/kg
Activity
Antiestrogenic
were active
[27]
Albino rats
Activity
reduction
weights
of
in
the
Female
Activity
rats[29]
Found to be active.
albino Leading
to
reduction
80%
In
the
implantation site on
10th
day
of
pregnancy.
Antilithiatic potential
In vitro assay[30]
very
inhibitory
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good
effect
against
crystal
nucleation,
growth
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Pekamwar et al.
& aggregation.
Cardio
protective Wistar
[31]
baseline changes in
effect
rats
cardiac endogenous
antioxidants.
Wound
healing Rats[32]
Found to be active
activity
2
Leaves
Antifungal Activity
Active
on Inhibition found to
activity
pedal
edema
of
rats[34]
Hair growth potential
Analgesic Activity
Mice[34]
Antipyretic Activity
Brewers
induced
Found to be active.
yeast Dose of 100mg/kg
pyrexia was active.
[34]
rats
scavenging activity
3
Stem
Root
Juvenile
assay[36]
Harmone Dysdercus
Found to be active
Activity
cingulatus[37]
Antipyretic activity
Swiss
rats[38]
Analgesic activity in
Swiss
rats[38]
Antiulcer Activity
Pyloric
method in rats[39]
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Antifertility Activity
female
rats[40]
Hypolipidaemic
Rats[41]
Found to be active
Activity
5
depressant Mice[23]
Dose of 500mg/kg
Activity
was active
Found to be active
Hypotensive Activity
Dogs[42]
A dose of 50mg/kg
was active.
Antipyretic Activity
Mice[23]
A dose of 500mg/kg
was active.
CONCLUSION
Hibiscus rosa sinensis possess many properties and this plant may procured at large scale for
providing herbal alternative to many diseases. This study shows that on biochemical basis
plant used in the treatment and prevention of various diseases and disorders. The
phytochemical screening on qualitative analysis shows that the plant is rich in alkaloids,
terpenoids, flavonoids, glycosides, reducing sugar, Fatty materials, saponins, gums and
mucilage.
ACKNOWLEDGEMENT
Authors are thankful to the School of Pharmacy, S R T M University, Nanded, for providing
necessary facilities.
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