09 Linear Forced Through Zero Calib PDF
09 Linear Forced Through Zero Calib PDF
09 Linear Forced Through Zero Calib PDF
Zero
Definition
A calibration curve defined using this
equation is forced to go through zero
intensity and zero concentration. This
It is often tempting to exclude the intercept, a, from the model because a zero stimulus on the x-axis should lead to a zero response on the y-axis.
However, the correct procedure is to fit the full model and test for the significance of the intercept term
calibration is established by assuming that
the relationship between concentration and
intensity is linear.
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Benefits
Simple; calibration can be represented
by y = mx.
Is correct when the origin (zero, zero) is
within the error of the measurement.
Ref:Roland Caulcutt and Richard Boddy, 1983,
"Statistics for Analytical Chemists," Chapman
and Hall, New York, ISBN 0-412-23730-X, p 91.
Disadvantages
Not best fit to data unless slope is the
same at all points.
Incorrect when points have responses
offset from zero (e.g., high blank).
Ref: Roland Caulcutt and Richard Boddy,
1983, "Statistics for Analytical Chemists,"
Chapman and Hall, New York, ISBN 0-41223730-X, p 91.