Dronsfield tcm18-200827 PDF
Dronsfield tcm18-200827 PDF
Dronsfield tcm18-200827 PDF
An early example of how blue skies research by Pierre and Marie Curie led to the treatment of
previously incurable cancers.
In short
Discovery
Fig 1
Radium therapy in
use an internal
radium applicator
to treat throat
cancer
adapted FROM BRITISH MEDICAL JOURNAL, J M H MACLEOD, 1904, 1, 1366, WITH PERMISSION FROM BMJ PUBLISHING GROUP
William Roentgen,
who discovered
x-rays
Marie Curie
(18671934)
Radium needles
implanted to treat
breast cancer
Marketed as a cure
for the living dead,
in 1932 one
enthusiastic
customer died of
radium poisoning
Further reading
R. F. Mould has written an excellent book on the early
References
1. E W Dahlgren, Nobel prize presentation speech, 1911.
See http://nobelprize.org/nobel_prizes/chemistry/
laureates/1911/press.html
2. H Becquerel, Comptes Rendus, 1896, 122, 420. See
http://web.lemoyne.edu/~giunta/ea/becquerelann.html
3. Quoted in R F Mould, Current Oncology, 2007, 14, 74.
Available (free) at http://www.ncbi.nlm.nih.gov/pmc/
articles/PMC1891197/
4. J H Sequeira, Brit. Med. Journal, Feb 15, 1915, 365.
5. J M H MacLeod, Brit. Med. Journal, June 11, 1904, 1366.
6. R H Herbst, J. Amer. Med. Assoc., 1919, 72, 1610.
7. Radium-223 is being used to relieve pain in bone
cancer. See http://clinicaltrials.gov/ct2/show/
NCT00667199
8. Medicine - radium drinks, Time Magazine, April 11,
1932. See http://www.time.com/time/magazine/
article/0,9171,743525,00.html
9. A T Dronsfield and P M Ellis, Educ. Chem., 2008, 45, 80.
10. M Curie, in a lecture given at Vassar College, May 14,
1921.
11. R F Mould, A Century of X-rays and Radioactivity in
Medicine. London: Taylor and Francis, 1993.
12. See, typically, http://www.boxvox.net/science/ and
http://www.fogonazos.es/2008/06/radio-activity-makesyou-feel-so.html
Acknowledgement
We are particularly grateful to Dr Alan J Gray, retired
Fig 2
Radioactive
toothpaste