Clinical Tract: Group Case Studies: Adult Arvs 19-1
Clinical Tract: Group Case Studies: Adult Arvs 19-1
Clinical Tract: Group Case Studies: Adult Arvs 19-1
Adult antiretroviral
therapy
The scenario
Mary is a 28 years old woman. She weighs 48kg. She complains of a painful
blister-rash for 2 days below the left breast. She is a known pulmonary TB
patient, on TB treatment for 1 month. She also takes co-trimoxazole. She
3
lost her newborn baby a week ago. Her recent CD4+ cell count is 150 cell/m .
On examination, she had herpes zoster infection (shingles). She was tearful
during the consultation due to severe pain.
The scenario
Betty is 30 years old. She had a CD4 count of 180 cells/mm3 and a viral load of 120
000 copies/mL. She w as diagnosed w ith HIV at 32 w eeks of pregnancy. The baby
received nevirapine syrup.
She initiated ARVs during pregnancy. At that stage she w eighed 58kg. She started
taking the follow ing drugs:
Stavudine 30mg orally 12 hourly
Lamivudine150mg tablet 12 hourly
Nevirapine 200mg tablet 12 hourly
Co-trimoxazole 480mg 2/day
She returns for her six month visit on ARV therapy. Her w eight is now 62kg. She has
no complains. Her pill count matches her diary. She has a calculated monthly
adherence of 98%. Her CD4 count is 220 cells/mm3 and her viral load is < 25
copies/mL.
Female patient, 47 years, 56kg, ARV nave. CD4 count 120 cells/mm3, viral load
95 000 copies/mL.
Treatment:
Stavudine 40mg bd
3 TC 150 mg bd
Efavirenz 600mg noct
Co-trimoxazole 480mg/day
Case 4
Female patient, 24 years, 56kg, ARV nave. CD4 count 120 cells/mm3, viral load
95 000 copies/mL.
Treatment
Combivir 1 bd
Efavirenz 600mg noct
Case 6
Mr Bokaba is a 34year old that has just been diagnosed w ith HIV infection.
His CD 4 count is 150cells / mm3 and his viral load is 100 000 copies/ml.
He is started on the follow ing Antiretroviral therapy:
Stavudine 30mg bd
Zidovudine 300mg bd
Efavirenz 600mg nocte
1. Stavudine 40mg bd
2. Didanosine 200mg bd
3. Efavirenz 600mg nocte
4. Rifafour4 tablets daily
5. Pyridoxine 30mg daily