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VTE Prophylaxis

This document provides guidelines for venous thromboembolism (VTE) prophylaxis in surgical patients. It outlines risk factors for VTE and hemorrhage in patients, including those related to patient characteristics like age, cancer, previous VTE, and immobility. Surgical risk factors like procedure type and duration of anesthesia or post-op immobility are also discussed. Methods of prophylaxis mentioned include chemical options like low-dose unfractionated heparin, low molecular weight heparins like enoxaparin, and fondaparinux. Mechanical prophylaxis includes graduated compression stockings and intermittent pneumatic compression devices.

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vistamaniac
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0% found this document useful (0 votes)
21 views

VTE Prophylaxis

This document provides guidelines for venous thromboembolism (VTE) prophylaxis in surgical patients. It outlines risk factors for VTE and hemorrhage in patients, including those related to patient characteristics like age, cancer, previous VTE, and immobility. Surgical risk factors like procedure type and duration of anesthesia or post-op immobility are also discussed. Methods of prophylaxis mentioned include chemical options like low-dose unfractionated heparin, low molecular weight heparins like enoxaparin, and fondaparinux. Mechanical prophylaxis includes graduated compression stockings and intermittent pneumatic compression devices.

Uploaded by

vistamaniac
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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VTE Prophylaxis

#surgery

There are several guidelines for VTE prophylaxis - including from an ANZ working party of the
management and prevention of VTE, and NHMRC clinical practice guidelines.

Risk factors for VTE and haemorrhage


Risk factors for VTE
Patient
Age (incidence rises each decade over 40)
Malignancy
Previous VTE
Obesity
Pregnancy and puerperium
Prolonged immobility - bed rest, plaster, travel
Oestrogen medication
Inherited/acquired thrombophilia
Deficiency - Protein C/S, ATIII deficiency
Presence of - anti-phospholipid antibodies, Factor V Leiden,
hyperhomocysteinaemia, prothrombin gene mutation (20210A)
Acute medical illness - CCF, AMI, CVA, sepsis, chemotherapy
Surgical procedure
Type
Duration of anaesthesia
Duration of post-op immobility
Complications
Risk factors for haemorrhage
Patient related
Ongoing bleeding - recent surgery/trauma, GI ulceration
CNS bleed
Coagulopathy - jaundice/meds
Bleeding disorders
Renal dysfunction
Fall risk
Prophylaxis related
Surgery (dose & timing)
Anaesthesia (epidural)
Methods of VTE prophylaxis
1. Chemical
LDUH, OR
LMWH
Enoxaparin (Clexane)
Dalteparin
Fondaparinux (ortho)
2. Mechanical
Stockings - TEDS or graduated compression stockings providing 16-20mmHg
pressure at the ankle
Contraindicated in PBD
IPC - intermittent pneumatic compression
Intraoperative, high-risk patients post-operatively

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