This document provides guidelines for venous thromboembolism (VTE) prophylaxis in surgical patients. It outlines risk factors for VTE and hemorrhage in patients, including those related to patient characteristics like age, cancer, previous VTE, and immobility. Surgical risk factors like procedure type and duration of anesthesia or post-op immobility are also discussed. Methods of prophylaxis mentioned include chemical options like low-dose unfractionated heparin, low molecular weight heparins like enoxaparin, and fondaparinux. Mechanical prophylaxis includes graduated compression stockings and intermittent pneumatic compression devices.
This document provides guidelines for venous thromboembolism (VTE) prophylaxis in surgical patients. It outlines risk factors for VTE and hemorrhage in patients, including those related to patient characteristics like age, cancer, previous VTE, and immobility. Surgical risk factors like procedure type and duration of anesthesia or post-op immobility are also discussed. Methods of prophylaxis mentioned include chemical options like low-dose unfractionated heparin, low molecular weight heparins like enoxaparin, and fondaparinux. Mechanical prophylaxis includes graduated compression stockings and intermittent pneumatic compression devices.
There are several guidelines for VTE prophylaxis - including from an ANZ working party of the management and prevention of VTE, and NHMRC clinical practice guidelines.
Risk factors for VTE and haemorrhage
Risk factors for VTE Patient Age (incidence rises each decade over 40) Malignancy Previous VTE Obesity Pregnancy and puerperium Prolonged immobility - bed rest, plaster, travel Oestrogen medication Inherited/acquired thrombophilia Deficiency - Protein C/S, ATIII deficiency Presence of - anti-phospholipid antibodies, Factor V Leiden, hyperhomocysteinaemia, prothrombin gene mutation (20210A) Acute medical illness - CCF, AMI, CVA, sepsis, chemotherapy Surgical procedure Type Duration of anaesthesia Duration of post-op immobility Complications Risk factors for haemorrhage Patient related Ongoing bleeding - recent surgery/trauma, GI ulceration CNS bleed Coagulopathy - jaundice/meds Bleeding disorders Renal dysfunction Fall risk Prophylaxis related Surgery (dose & timing) Anaesthesia (epidural) Methods of VTE prophylaxis 1. Chemical LDUH, OR LMWH Enoxaparin (Clexane) Dalteparin Fondaparinux (ortho) 2. Mechanical Stockings - TEDS or graduated compression stockings providing 16-20mmHg pressure at the ankle Contraindicated in PBD IPC - intermittent pneumatic compression Intraoperative, high-risk patients post-operatively