Toxicology
Toxicology
Toxicology
2010
26. The percentage of oxygen which is indicated for carbon monoxide poisoning to increase the
conversion of carboxyhemoglobin to hemoglobin and myoglobin and to increase oxygen
saturation of the plasma is:
a. 50%
b. 75%
c. 100%
d. 10%
a. aniline
b. ammonium hydroxide
c. acetone
d. phosphoric acid
28. Convulsions caused by drugs poisoning are most commonly associated with:
a. Phenobarbital
b. diazepam
c. strychnine
d. chlorpromazine
29. Alkalinizing the urine with sodium bicarbonate is useful in the treatment of poisoning with:
30. Activated charcoal may be used in the treatment of these poisoning, except:
a. Phenobarbital
b. propoxyphene
c. aspirin
d. methanol
31. These statements regarding carbon monoxide poisoning are true, except:
a. streptomycin
b. ethacrynic acid
c. furosemide
d. tetracyclines
33. Indivduals who are deficient in glucose-6-dehydrogenase experience hemolysis the treatment
with these drugs, except:
a. dapsone
b. ethacrynic acid
c. primaquine
d. tetracyclines
a. nitrous oxide
b. enflurane
c. ketamine
d. thiopental sodium
35. Direct hepatotoxicity has been observed with the following anesthetic agents:
a. halothane
b. nitrous oxide
c. thiopental
d. all of the above
36. A patient has resulted in acute hypertensive crisis after eating cheese. This interaction is
possible if the patient is on:
a. MAO inhibitor
b. aspirin
c. tetracyclines
d. all of the above
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37. It is used in the manufacture of smoke bomb, antiseborrheic shampoos, in the treatment of
bone fracture and rickets.
a. bismuth
b. boron
c. cadmium
d. cesium
e. chromium
38. Its deficiency mimics diabetes mellitus, it is found in brown sugar and butter
a. bismuth
b. boron
c. camium
d. cesium
e. chromium
a. bismuth
b. boron
c. cadmium
d. cesium
e. chromium
a. nitrite
b. naphthalene
c. oxalate
d. lead
e. mercury
a. nitrite
b. naphthalene
c. oxalate
d. lead
e. mercury
a. nitrite
b. naphthalene
c. oxalate
d. lead
e. mercury
a. nitrite
b. naphthalene
c. oxalate
d. arsenic
e. beryllium
a. nitrite
b. naphthalene
c. oxalate
d. arsenic
e. beryllium
a. aniline
b. cyanide
c. ethyl alcohol
d. iodine
e. formaldehyde
a. aniline
b. cyanide
c. ethyl alcohol
d. iodine
e. formaldehyde
a. aniline
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b. cyanide
c. ethyl alcohol
d. iodine
e. formaldehyde
a. aniline
b. cyanide
c. ethyl alcohol
d. iodine
e. formaldehyde
a. hydrogen sulfide
b. carbon monoxide
c. carbon disulfide
d. nitrogen oxygen
a. hydrogen sulfide
b. phosphorus
c. carbon disulfide
d. carbon tetrachloride
e. carbon monoxide
51. The abuse of this drug is responsible for major medical and socio-economic problems:
a. chloral hydrate
b. chloral hydrate and ethancl
c. nitrous oxide
d. ethanol
52. Poisoning due to anticholinesterase is the best managed by the administration of:
a. theophylline
b. atropine
c. salbutamol
d. ethanol
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53. Conjuctival and bronchial irritation are primary signs of exposure to:
a. ergot
b. sulfur dioxide
c. ethyl alcohol
d. mercury
a. iron
b. methanol
c. calcium
d. iodine
a. ethyl alcohol
b. methane
c. nitrogen
d. none of these
a. sourine
b. nenerupin
c. gemblid
d. potassium bromate
58. A type of poison that causes blackening and severe corrosion in the mouth:
a. nitric acid
b. sulfuric acid
c. phenol
d. hydrochloric acid
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59. It causes the Minamata disease:
a. Nickel
b. Manganese
c. Molybdenum
d. Mercury
a. phenoxyacetic acid
b. paraquat
c. diquat
d. nicotine
a. belladonna
b. digitalis
c. amanita phalloides
d. all of these
a. nitrite
b. lead
c. naphthalene
d. oxalate
a. barium sulfate
b. BAL with EDTA
c. Ethanol
d. Naloxone
a. ethanol
b. digoxin
c. atropine
d. naloxone
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65. Induction of vomiting is accomplished by administering:
a. syrup of ipecac
b. ginger ale
c. peppermint syrup
d. none of these
66. Banned toxic substance in “pandesal”, cakes and other bakery products:
a. gemblid
b. venrupin
c. potassium bromate
d. sourine
a. 5 grains
b. 5 grams
c. 5 mg
d. All of these
a. dilated pupil
b. hallucinations and dilated pupil
c. hallucinations
d. none of these
a. fatigue
b. fatigue of respiratory muscle
c. cardiac failure
d. exhaustion of respiratory center
a. magnesium oxide
b. lead oxide
c. arsenic trioxide
d. nitrous oxide
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71. Manihotoxin is found in this crop root:
a. yam
b. cassava
c. sweet potatoes
d. none of these
a. codeine
b. pilocarpine
c. barbiturate
d. morphine
a. violent syndrome
b. coma with open eyes
c. coma with open eyes and violent syndrome
d. none of these
a. ciguatoxin
b. saxitoxin
c. aflatoxin
d. scombroid
a. aromatic compounds
b. all of these
c. alkaloid
d. none of these
a. diazepam
b. strychnine
c. phenobartibal
d. chlorpromazine
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77. A carcinogenic substance found in stale peanut:
a. peroxide
b. glyceryl ester
c. aflatoxin
d. fatty acid
a. neostigmine
b. lactrotoxin
c. carbachol
d. all of these
a. adrenaline
b. atropine
c. amphetamine
d. barbiturate
a. antimony
b. aluminum
c. barium
d. arsenic
a. lead
b. copper
c. gold
d. gallium
a. mercury
b. cyanide
c. lead
d. none of these
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83. Paraquat poisoning is characterized by:
a. bloody stool
b. none of these
c. hematemesis
d. bloody stool and hematemesis
84. The universal antidote usually contains tannic acid, activated charcoal and:
a. calcium hydroxide
b. aluminum hydroxide
c. magnesium oxide
d. all of these
a. phenacetin
b. picric acid
c. picrotoxin
d. colchicines
a. caffeine
b. apomorphine
c. ergonovine
d. emetine
a. dinoflagellates
b. snails
c. jellyfish
d. octopus
a. morphine
b. dimercaprol
c. EDTA
d. None of these
a. ataxia
b. drowsiness
c. seizures
d. none of these
a. scombroid
b. venom
c. saxitoxin
d. tetrodotoxin
a. malthion
b. pyrethrum
c. parathrion
d. none of these
a. hyaluronidase
b. urease
c. steapsin
d. ptyalin
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95. The effects that occur at the site of the first contact between the biological system and the
toxicant.
a. Local toxicity
b. Economic toxicity
c. Systemic toxicity
d. Cumulative toxicity
a. oxalic acid
b. naphthalene
c. activated charcoal
d. arsenic
e. none of these
97. Poison that converts the red hemoglobin to chocolate brown color
a. aniline
b. nitrobenzene
c. both a and b
d. ether
a. sulfuric acid
b. acetic acid
c. hydrochloric acid
d. none of the above
a. cresol
b. phenol
c. resorcinol
d. thymol
a. mushrooms
b. dried nuts
c. marine animal
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d. snake
a. toxin
b. phytotoxin
c. bufotoxin
d. syntoxin
103. Yellow or disturbed vision, disturbed respiration, epileptiform convulsion can be caused by:
a. santonin
b. muscarine
c. atropine
d. all of these
e. none of these
104. Oxidation of pyrocatechol and hydroquinol may tint the urine with color _____
a. black
b. yellow
c. blue
d. green
e. none of these
a. pilocarpine
b. atropine
c. morphine
d. codeine
106. A branch of toxicology which is concerned with the medical and legal consequences of
poisoning:
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a. environmental toxicology
b. experimental toxicology
c. forensic toxicology
d. economic toxicology
107. Mineral oil is an antidote for kerosene poisoning. Its mechanism of action is
a. adsorption
b. neutralization
c. inactivation
d. lessening respiratory hazard by increasing viscosity of kerosene
a. muscarine
b. atropine
c. picrotoxin
d. both a and b
e. none of the
a. nitrogen pentoxide
b. nitric oxide
c. nitrogen oxide
d. all of these
e. none of these
a. lemon juice
b. saline solution
c. ammonia
a. lead
b. mercury
c. copper
d. silver
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112. The alkaloid found in Ipecac used for amoebic dysentery was evident poisoning symptom is
violent purging with bloody stools:
a. ephedrine
b. emetine
c. isoquinoline
d. methylxanthine
a. water
b. ethanol
c. soap
d. all of these
114. Peculiar stimulation (tingling) and paresthesia (numbness) of the sensory in nerves are
symptoms of poisoning due to:
a.aconite b.muscarine c.atropine d.physotigmine
115. Potent cord convulsant, increases the excitability of the CNS at all level
a.morphine b.opium c.strychnine d.both a and b
116. Obtained from coal tar
a.kerosene b.napthaline c.both a and b d.none of these
121. Insecticide, fungicide, alloys in medicine, emetic drug, astringent and caustic, purification
of water, escharotics
a.cadmium b.copper c.lead d.mercury e.none of the above
122. Ultra short acting barbiturates are highly lipid soluble and rapidly penetrate the brain, and is
capable of inducing:
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a.anesthesia b.paralysis c.none of the above
131. Example of poison which exhibits both local and remote types of effects
a.arsenic b.cantharides c.both a and b d.none of the above
132. Substance intended to prevent, destroy, repel or mitigate rats, mice, etc
a.herbicides b.hematocides c.rodenticides d.molluscides
140. Which of the ff. animals used for flocculant precipitates with human blood?
a.cat b.dog c.rabbit d.monkey
142. Strong black coffee subcutaneous injection of caffeine citrate in the treatment of acute
alcohol poisoning is done because of the
143. The cardinal rule or the first step to be considered in the treatment of poisoning is to:
a.remove the poison from contact with the victim b.stop the action of the poison by
giving the specific antidote c.provide symptomatic supportive care d.fight against the
tendency of death
147. The mechanism of action involved in the use of EDTA as andtidote for heavy metal
poisoning is:
a.adsorption b.oxidation c.chelation d.precipitation
148. The ff. symptoms of poisoning from antimony are similar to those of arsenic poisoning
except:
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a.diarrhea of rice-water stool b.severe dehydration and great thirst c.garlic odor
of breath and suppression of urine d.nausea and vomiting
162. A red color in the pyridine layer after adding NaOH develops in the presence of
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a.nitrobenzine b.chloroform c.ethylene d.phenacetin
178. The process of detoxification wherein the drug/substance of abuse is withdrawn gradually
a.cold turkey b.warm turkey c.luke-warm turkey d.hot turkey
180. “Roofies”
a.alprazolam b.cannabis c.flunitrazepam d.heroin
181. A toxic insult on the developing organism may cause adverse effect during
a.prenatal development b.postnatal development c.prior to conception d.all of the
above
184. All of the following metals had been found with substantial evidence to be carcinogenic in
humans except
a.arsenic b.beryllium c.cadmium d.manganese
187. Exposures at anytime during pregnancy poses a high risk congenital structural abnormalities
a.tretinoin b.cyclophosphamide c.carbamapezine d.tamoxifen
188. Enters the breast milk and can cause neonatal narcotic dependence
a.heroin b.codaine c.both a and b d.none of these
193. Ethanol acts by preventing the conversion of this drug to formaldehyde by competing for
dehydrogenase
a.chlorine b.iodine c.methanol d.all of these
212. the following antidotes could be used to treat carbamate insecticides poisoning except
a. atropine b. pralidoxime c.physostigmine d. all of these
213. an antidote that acts by adsorption and is usually given when nature of the poison is
unknown
a. KMnO4 b. ipepac syrup c. tannic acid d. charcoal
215. non-therapeutic chemical most commonly involved in poisoning are the following except
a. corrosives b. insecticides c. solvents d. analgesics
221. the specific antidote for the treatment of poisoning due to oral ingestion of silver nitrate
a. Normal saline b. Dimecaprol c. Atropine d.Lead e.Neogmine
224. the most effective antidote for arsenic, gold and mercury poisoning, whing is metal
complexing agent
a. Normal saline b. Dimecaprol c. Atropine d.Lead e.Neogmine
226. this is indicated for severe metabolic acidosis resulting to intoxication by methanol. Ethlyne
glycol, salicylates, and excessive lactic acid.
a.Diazoxide b. Diazepam c.Syrup of ipepac d. Charcoal e.Sodium bicarbonate
227. this is indicated for anxiety, convulsions, muscle relaxant and chloroquine poisoning to
antagonize cardiac toxicity.
a.Diazoxide b. Diazepam c.Syrup of ipepac d. Charcoal e.Sodium bicarbonate
229. an antidote that acts by adsorption that is usually given when the nature of the poison is
unknown
a.Diazoxide b. Diazepam c.Syrup of ipepac d. Charcoal e.Sodium bicarbonate
232. the antidote for treating poisoning with bleaching agents like zonrox
a.ammonia water b.2.5% sodium thiosulfate c. atropine d. BAL with EDTA e. pyridoxine
233. the best antidote for formaldehyde poisoning, since it forms a non-poisonous product which
is methanamine
a.ammonia water b.2.5% sodium thiosulfate c. atropine d. BAL with EDTA e. pyridoxine
238. this B-complex vitamin, when administered to patients with methanol and ethylene glycol
poisoning, may enhance the elimination of the toxic metabolite, formic acid
a. acetylcysteine b. weak acid c. starch d. activated charcoal e. folic acid f. calcium
gluconate
239.this drug is indicated for acetaminophen overdose, which acts as a sulfhydyl group donor,
substituting for the liver’s usual sulfhydryl donor glutathione
a. acetylcysteine b. weak acid c. starch d. activated charcoal e. folic acid f. calcium
gluconate
242.glucose with this drug is given to alcoholic and malnourished patient but may aggravate
hyperglycemic ischemia and brain injury
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a. acetylcycysteine b. physostigmine c. potassium salt d. thiamine e. ethanol
254. surface contamination with phenol can be washed using this substance
a. atropine/pralidoxime b. magnesium oxide c. castor oil d.naloxone e.sodium
bicarbonate
255. the universal antidote usually contains tannic acid, activated charcoal and this drug
a. atropine/pralidoxime b. magnesium oxide c. castor oil d.naloxone e.sodium
bicarbonate
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256. theses drug can treat poisoning with organphosphates like parathion and mathion
a. atropine/pralidoxime b. magnesium oxide c. castor oil d.naloxone e.sodium
bicarbonate
270. exerts their effects by interfering with the oxidation of the tissues
a. narcotics b. irritants c. asphyxiants d. convulsants
273. a condition of more or less complete suspension of respiration and death may begin at the
lungs:
a. syncope b. coma c. asphyxia d. drowning
274. agents which produce exhaustion and cause marked loss of vital or muscular power
a. tetanics b. neurotics c. narcotics d. convulsants
276. evidence obtained by examination of body organs and tissues after death
a. experimental evidence b. chemical evidence c. post-mortem evidence d. pre-mortem
evidence
278. evidence obtained by administering the suspected substance to some living animal and
observing the effects
a. circumstantial evidence b. symptomatic evidence c. experimental evidence d. chemical
evidence
279. a type of poisoning produced by taking or absorbing for a protracted period small doses of a
poison, thereby producing gradual deterioration of function of tissues
a. acute poisoning b. sub-acute poisoning c. chronic poisoning d. none of these
280. dose which may be expected ordinarily to produce the therapeutic effects for which the
preparation is employed.
a. maximum dose b. minimum dose c. average dose d. above average dose
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281.atmospheric substance with an oxidizing power which liberates iodine from solution of KI.
a. carbon monoxide b. oxidants c. particulates d. hydrogen sulfide
283. characteristic color of the ammonium phosphor-molybdate precipitate for the presence of
phosphorous
a. violet precipitate b. black precipitate c. yellow precipitate d. maroon precipitate
284. characteristic type of precipitate of magnesium ammonium phosphate for the presence of
phosphorous
a. curdy, white precipitate b. heavy white precipitate c. yellow precipitate d. white solution