Therapy Worksheet (Page 1 of 2) : A. VALIDITY: Are The Results of This Single Preventive or Therapeutic Trial Valid?
Therapy Worksheet (Page 1 of 2) : A. VALIDITY: Are The Results of This Single Preventive or Therapeutic Trial Valid?
Therapy Worksheet (Page 1 of 2) : A. VALIDITY: Are The Results of This Single Preventive or Therapeutic Trial Valid?
A. VALIDITY: Are the results of this single preventive or therapeutic trial valid?
B. IMPORTANCE
Sample calculations:
Your calculations:
Method II: 1 / (PEER x RRR) PEER = Your patient’s expected event rate if
they received the control treatment = ……..
(NNT for patients like yours) =
1 / (PEER x RRR) = 1/ ………….= ………
2. Are your patient’s values and preferences satisfied by the regimen and its
consequences?
Do your patient and you have a clear
assessment of their values and
preferences?
Additional Notes:
SYSTEMATIC REVIEW WORKSHEET (page 1 of 2)
___1 - {PEER x (1 -
OR)}____
NNT = (1 - PEER) x PEER x (1 -
OR)
Are your patient’s values and preferences satisfied by the regimen and its
consequences?
Do your patient and you have a clear
assessment of their values and
preferences?
Should you believe apparent qualitative differences in the efficacy of therapy in some
subgroups of patients? Only if you can say “yes” to all of the following:
1. Do they really make biologic and clinical sense?
2. Is the qualitative difference both clinically (beneficial for some but useless or harmful for
others) and statistically significant?
3. Was this difference hypothesised before the study began (rather than the product of
dredging the data), and has it been confirmed in other, independent studies?
4. Was this one of just a few subgroup analyses carried out in this study?
Additional Notes:
DIAGNOSIS WORKSHEET (page 1 of 2)
YOUR CALCULATIONS:
Target Disorder Totals
Present Absent
Diagnostic Positive a b a+b
Test Result
Negative c d c+d
Additional Notes:
PROGNOSIS WORKSHEET (page 1 of 2)
Can you apply this valid, important evidence about prognosis in caring for your
patient?
1. Were the study patients similar to your
own?
Additional Notes:
HARM/AETIOLOGY WORKSHEET: Page 1 of 2 Sackett June 1996
In this study:
HARM/AETIOLOGY WORKSHEET: Page 2 of 2
Should these valid, potentially important results of a critical appraisal about a harmful
treatment change the treatment of your patient?
1. Can the study results be extrapolated to
your patient?
Additional Notes:
Citation:
3. Is it worth it?
If a cost-minimisation analysis, is the
difference in costs big enough to warrant
switching over to the cheaper one?
Additional Comments:
DECISION ANALYSIS WORKSHEET: Page 1 of 1 Sackett Revised July 20, 1996
Citation:
Are the results of this clinical decision analysis valid?
Additional Notes:
GUIDELINES WORKSHEET: Page 1 of 2 Sackett Revised July 21, 1996
Citation:
Additional Comments: