Cell and Molecular Biology Study Guide
Cell and Molecular Biology Study Guide
Cell and Molecular Biology Study Guide
A cell needs a receptor for a particular signal to have a response to a signal molecule.
Long range signaling is endocrine and synaptic.
Neurons associated with synaptic.
Paracrine and contact short range
“public” is endocrine
”molecular switches” in signaling are kinases and GTP-binding proteins
3 classes cell surface receptors: enzyme-coupled, ion channel, g protein coupled receptors
G protein larges family
G protein crosses membrane 7 times
Mutated often in human cancer, constitutively active gene is Ras