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    Blue Biotechnology Part PDF

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    Rene Ramilo
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    Blue Biotechnology Part PDF

    Uploaded by

    Rene Ramilo
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    189 views11 pages

    Blue Biotechnology Part PDF

    Uploaded by

    Rene Ramilo
    good

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 11

    Blue biotechnology

    new opportunities for EU


    Limits, achievements and
    perspectives

    J. QUERELLOU, PhD
    Ifremer, France
    What is blue biotechnology?
    - Drugs
    Products - Elicitors
    Marine living Aquaculture - Biofuels
    resources - Food
    - Enzymes
    - Biopolymers
    - Organic
    compounds
    - Basic research
    Biotechnology Services - Ecosystem
    Toolbox: Management
    - biodiscovery - Bioremediation
    - mol. biology
    - biochemistry
    - microbiology Global market: B€ 1.9
    - …omics Annual growth: 10%
    - etc.

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    Blue biotechnology and food issue?

    1. Optimisation of aquaculture production systems


    - omics applied to aquaculture
    - high opportunities of transgenic products BUT?
    - improved microbial control of farming and health
    - quality/traceability/management of fish/shellfish

    2. Optimisation of aquaculture products contents for health


    - beneficial effects of sea-food
    - optimisation of composition
    through control of feed quality
    - production of neutraceuticals

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    Blue biotechnology and energy issue?
    1. Microbial Enhanced Oil Recovery (MEOR)?
    - huge potential and high economical impacts
    - controversial results and no clear strategy in Europe
    - future policy to be clarified and recommendations
    for research discussed
    2. Marine products for the second biofuel generation?
    - Enzymes from marine organisms degrading
    lignocellulosic products
    - Integration of marine enzymes in industrial process
    3. MB and the third biofuel generation based on microalgae
    - High interest to produce biodiesel
    - Initiatives in R&D in the USA and Europe
    - Economical en environmental sustainability?
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    Blue biotechnology and health issue?
    1. Achievements of the last 20 years
    - Prialt™, Yondelis, and close to 20 compounds
    under trials
    - Renewal of interest for natural products
    2. But many constraints and challenges
    - legal aspects, access, property rights, IP
    - quality of marine resources, id, sustainab.
    - dereplication and shared information
    - strutural costs from marine products
    - strategies of SMEs and big pharmas
    3. Antibioresistance and deficit of novel
    antibiotics: toward post-antibiotic era?

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    Blue biotechnology and
    environmental issues?
    1. Biofouling/antifouling
    - critical env. issue and huge economic importance
    - promising results but no commercial hits
    - need for research and integration of green AF and
    nanostructured coating
    2. Detection of marine bacteria, viruses, toxic compounds
    - active community for designing molecular tools
    DNA probes, PCR solutions, SPR in situ etc…
    3. Monitoring of chemicals
    - need for efficient biological assessment tools
    - model organisms as integrating tools?
    4. Bioremediation
    - oil spills: progress and limits. Policies?

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    Blue biotechnology
    as a source of innovative products?
    1. Proteins and enzymes (notably extremophiles)
    - Large range of applications: white biotech, feed,
    energy, environment, etc.
    - Need for improved high throughput direct
    screening from crude sample
    2. Biopolymers (EPS, PHA, etc.)
    - Large range of applications: cosmetics,
    health, bioremediation, etc.
    3. Biomaterials
    - Novel field of research

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    Blue biotechnology: vision for the future
    By 2020 European Union will develop and
    apply advanced tools,
    platforms and infrastructures and support
    to Marine Biotechnology to provide a
    significant contribution to addressing key
    societal challenges of the next decades in
    the areas of food and energy,
    development of novel drugs and
    treatments for human health and the
    sustainable use and management of the
    seas and oceans.
    - Naive if not supported by an appropriate strategy and a
    strong implementation plan and constant support of all key players
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    Blue biotechnology
    what conditions for success?
    - Access to resources
    - property rights in EEZ and the zone and IP
    - no common policy except general trend to exclusive protection
    - sustainability of resources
    - shared information and dereplication

    -Shared or distributed infrastructures and equipments


    - Network of marine stations (ASSEMBLE and EUROFLEETS…)
    - Omics infrastructures
    - Biobanks and biological resources centres

    RE.gif
    Blue biotechnology: what strategy?
    Establish completely new mechanisms and policies to circumvent
    the high risks of investments in critical novel drugs from marine
    resources, notably antibiotics

    Improve policies in property rights and IP

    Develop a common European position


    on regulations of access benefit sharing
    and exploitation of marine
    genetic resources

    Support the emergence of joint


    research groups acad/industry
    RE.gif
    Blue biotechnology challenge

    Special thanks to
    Jan-Bart Calewaert, ESF
    and MB WG members
    RE.gif

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