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    Krebs Cycle PDF

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    Smexy Patata
    1. Pyruvate is converted to acetyl-CoA through a two step process where pyruvate first loses carbon dioxide and is converted to acetyl group, producing NADH, then the acetyl group attaches to coenzyme A to form acetyl-CoA. 2. The Krebs cycle breaks down acetyl-CoA to form CO2, NADH, ATP, and FADH2 through 8 steps catalyzed by specific enzymes, where acetyl-CoA combines with oxaloacetate to start the cycle which decomposes citric acid and produces electron carriers and ATP over 7 steps to complete the cycle. 3. The Krebs cycle connects glycolysis to the electron transport chain by producing

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    Krebs Cycle PDF

    Uploaded by

    Smexy Patata
    104 views32 pages
    1. Pyruvate is converted to acetyl-CoA through a two step process where pyruvate first loses carbon dioxide and is converted to acetyl group, producing NADH, then the acetyl group attaches to coenzyme A to form acetyl-CoA. 2. The Krebs cycle breaks down acetyl-CoA to form CO2, NADH, ATP, and FADH2 through 8 steps catalyzed by specific enzymes, where acetyl-CoA combines with oxaloacetate to start the cycle which decomposes citric acid and produces electron carriers and ATP over 7 steps to complete the cycle. 3. The Krebs cycle connects glycolysis to the electron transport chain by producing

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    1. Pyruvate is converted to acetyl-CoA through a two step process where pyruvate first loses carbon dioxide and is converted to acetyl group, producing NADH, then the acetyl group attaches to coenzyme A to form acetyl-CoA. 2. The Krebs cycle breaks down acetyl-CoA to form CO2, NADH, ATP, and FADH2 through 8 steps catalyzed by specific enzymes, where acetyl-CoA combines with oxaloacetate to start the cycle which decomposes citric acid and produces electron carriers and ATP over 7 steps to complete the cycle. 3. The Krebs cycle connects glycolysis to the electron transport chain by producing

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    104 views32 pages

    Krebs Cycle PDF

    Uploaded by

    Smexy Patata
    1. Pyruvate is converted to acetyl-CoA through a two step process where pyruvate first loses carbon dioxide and is converted to acetyl group, producing NADH, then the acetyl group attaches to coenzyme A to form acetyl-CoA. 2. The Krebs cycle breaks down acetyl-CoA to form CO2, NADH, ATP, and FADH2 through 8 steps catalyzed by specific enzymes, where acetyl-CoA combines with oxaloacetate to start the cycle which decomposes citric acid and produces electron carriers and ATP over 7 steps to complete the cycle. 3. The Krebs cycle connects glycolysis to the electron transport chain by producing

    Copyright:

    © All Rights Reserved
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    of 32

    John Harvie E.

    Romeroso
    Transition Reaction or Oxidation of
    Pyruvate to Acetyl CoA
    Connects glycolysis to the
    Krebs cycle.
    In the
    Mitochondrion.
    1. Each pyruvate molecule (3-C)
    loses carbon dioxide and is
    converted to 2-C acetyl group or
    acetic acid. It will produce NADH.
    2. Acetate is attached to coenzyme
    A to form acetyl-CoA.
    Requirements: Products:
    2 Pyruvate 2 CO2 (Waste)
    2 NAD 2 NADH
    2 Coenzyme A 2 Acetyl-CoA
    Krebs
    Cycle

    Completes the break down of pyruvate


    to CO2
    In the Mitochondrial Matrix
    Krebs
    Cycle

    Consists of a set of reactions that


    breaks down acetyl-CoA to form CO2,
    NADH, ATP, and FADH2 .
    ▪ Has eight steps, each catalyzed by a
    specific enzyme.
    ▪ Acetyl group of acetyl CoA joins the
    cycle by combining with
    oxaloacetate.
    ▪ The next seven steps decompose
    the citric acid back to oxaloacetate,
    making the process a cycle.
    ▪ The NADH and FADH2 produced by
    the cycle relay electrons extracted
    from food to the electron transport
    chain.
    1. Acetyl-CoA combines with 4-C
    compound oxaloacetic acid to
    form 6-C compound known as
    citric acid.
    2. Citric acid is broken down into two
    molecules of CO2, one ATP, three
    NADH, and one FADH2.
     Since there are two pyruvic acid
    molecules, there will be two turns of
    Krebs Cycle.
    3. Finally, acetyl-CoA and citric acid
    are generated and the cycle
    continues.
    Transition
    Reaction
    Requirements: Products:
    2 Acetyl CoA 4 CO2 (Waste)
    6 NAD 6 NADH
    2 FAD 2 FADH2
    2 ADP 2 ATP
    John Harvie E. Romeroso

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