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Perhitungan Uji Disolusi

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Shela Said

The document describes calculations related to determining phosphate concentrations over time in multiple replications of an experiment. It provides phosphate concentration values (in ppm) at several time points for 6 replications of the experiment. It also shows the formulas used to calculate concentration values at each time point by taking into account the concentration from the previous time point plus additional phosphate introduced. The goal is to model phosphate concentration change over time and account for variations between replications.

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Perhitungan Uji Disolusi

Uploaded by

Shela Said
121 views31 pages
The document describes calculations related to determining phosphate concentrations over time in multiple replications of an experiment. It provides phosphate concentration values (in ppm) at several time points for 6 replications of the experiment. It also shows the formulas used to calculate concentration values at each time point by taking into account the concentration from the previous time point plus additional phosphate introduced. The goal is to model phosphate concentration change over time and account for variations between replications.

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The document describes calculations related to determining phosphate concentrations over time in multiple replications of an experiment. It provides phosphate concentration values (in ppm) at several time points for 6 replications of the experiment. It also shows the formulas used to calculate concentration values at each time point by taking into account the concentration from the previous time point plus additional phosphate introduced. The goal is to model phosphate concentration change over time and account for variations between replications.

Copyright:

© All Rights Reserved
Download as DOCX, PDF, TXT or read online from Scribd
Download as docx, pdf, or txt
121 views31 pages

Perhitungan Uji Disolusi

Uploaded by

Shela Said
The document describes calculations related to determining phosphate concentrations over time in multiple replications of an experiment. It provides phosphate concentration values (in ppm) at several time points for 6 replications of the experiment. It also shows the formulas used to calculate concentration values at each time point by taking into account the concentration from the previous time point plus additional phosphate introduced. The goal is to model phosphate concentration change over time and account for variations between replications.

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2.

Perhitungan

perhitungan media

Dapar phosphat = 7,4

pKa Na2HPO4 = 7,2

BM Na2HPO4 = 142,1

BM Na2H2PO4 = 120,1

log HPO42
7,4 = 7,3 +
log H 2 PO4

log HPO42
0,2 =
log H 2 PO4

HPO42- = 1,58 H2PO4-

Ka = antilog (-7,2) = 6,31 × 10-8

[H3O+] = antilog (-7,4) = 3,98 × 10-8

2,3CKa[ H 3O  ]
β=
( Ka  [ H 3O  ]) 2

2,3C (6,31108 )(3,98 108 )


0,1 =
((6,31108 )  (3,98 108 )) 2

2,3C (2,511015 )
0,1 =
10,58 

1,059 = 5773 C

C = 0,183

C = [HPO42-] + [H2PO4-]
0,183 = 1,58 H2PO4 + H2PO4-

H2PO4- = 0,071

H2PO4- = 0,12

H2PO4- = 0,071 ×120,1 = 8,527 gram

HPO42- = 0,112 × 142,1 = 15,91 gram

Dalam 50 mL

50
H2PO4 = × 8,527 gram = 0,43 gram
100

50
HPO42- = × 15,91 gram = 0,8 gram
100

a. Konsentrasi

Y=BX+A

A = 0,0628

B = ,02952
0

1) Replikasi pertama

Menit ke 0

Y=BX+A

X=0

Menit ke - 5

0,246 = 0,02952 X + 0,0628


0,02952 X = 0,246 - 0,0628

X = 6,104

Menit ke - 10

0,363 = 0,02952 X + 0,0628

0,02952 X = 0,363 - 0,0628

X = 10,169

Menit ke - 20

0,502 = 0,02952 X + 0,0628

0,02952 X = 0,502 - 0,0628

X = 14,878

Menit ke - 30

0,646 = 0,02952 X + 0,0628

0,02952 X = 0,646 - 0,0628

X = 19,756

Menit ke - 45

0,643 = 0,02952 X + 0,0628

0,02952 X = 0,643 - 0,0628


X = 19,654

Menit ke - 60

0,634 = 0,02952 X + 0,0628

0,02952 X = 0,634 - 0,0628

X = 19,349

2) Replikasi kedua

Menit ke - 0

Y=BX+A

X=0

Menit ke - 5

0,247 = 0,02952 X + 0,0628

0,02952 X = 0,247 - 0,0628

X = 6,239

Menit ke - 10

0,364 = 0,02952 X + 0,0628

0,02952 X = 0,364 - 0,0628

X = 10,203
Menit ke - 20

0,549 = 0,02952 X + 0,0628

0,02952 X = 0,549 - 0,0628

X = 16,470

Menit ke - 30

0,649 = 0,02952 X + 0,0628

0,02952 X = 0,649 - 0,0628

X = 19,857

Menit ke - 45

0,644 = 0,02952 X + 0,0628

0,02952 X = 0,644 - 0,0628

X = 19,688

Menit ke - 60

0,635 = 0,02952 X + 0,0628

0,02952 X = 0,635 - 0,0628

X = 19,383
3) Replikasi ketiga

Menit ke - 0

Y=BX+A

X=0

Menit ke - 5

0,251 = 0,02952 X + 0,0628

0,02952 X = 0,251 - 0,0628

X = 6,375

Menit ke - 10

0,309 = 0,02952 X + 0,0628

0,02952 X = 0,309 - 0,0628

X = 8,340

Menit ke - 20

0,549 = 0,02952 X + 0,0628

0,02952 X = 0,549 - 0,0628

X = 16,470

Menit ke - 30

0,648 = 0,02952 X + 0,0628


0,02952 X = 0,648 - 0,0628

X = 19,823

Menit ke - 45

0,649 = 0,02952 X + 0,0628

0,02952 X = 0,649 - 0,0628

X = 19,857

Menit ke - 60

0,630 = 0,02952 X + 0,0628

0,02952 X = 0,630 - 0,0628

X = 19,214

4) Replika keempat

Menit ke - 0

Y=BX+A

X=0

Menit ke - 5

0,238= 0,02952 X + 0,0628

0,02952 X = 0,238 - 0,0628

X = 5,934
Menit ke -10

0,367 = 0,02952 X + 0,0628

0,02952 X = 0,367 - 0,0628

X = 10,304

Menit ke - 20

0,505 = 0,02952 X + 0,0628

0,02952 X = 0,505 - 0,0628

X = 14,979

Menit ke - 30

0,643 = 0,02952 X + 0,0628

0,02952 X = 0,643 - 0,0628

X = 19,654

Menit ke - 45

0,639 = 0,02952 X + 0,0628

0,02952 X = 0,639 - 0,0628

X = 19,518
Menit ke - 60

0,640 = 0,02952 X + 0,0628

0,02952 X = 0,640 - 0,0628

X = 19,552

5) Replika kelima

Menit ke - 0

Y=BX+A

X=0

Menit ke - 5

0,248 = 0,02952 X + 0,0628

0,02952 X = 0,248 - 0,0628

X = 6,273

Menit ke - 10

0,362 = 0,02952 X + 0,0628

0,02952 X = 0,362- 0,0628

X = 10,135

Menit ke - 20
0,510 = 0,02952 X + 0,0628

0,02952 X = 0,510 - 0,0628

X = 15,149

Menit ke - 30

0,644 = 0,02952 X + 0,0628

0,02952 X = 0,644 - 0,0628

X = 19,688

Menit ke - 45

0,640 = 0,02952 X + 0,0628

0,02952 X = 0,640 - 0,0628

X = 19,552

Menit ke - 60

0,634 = 0,02952 X + 0,0628

0,02952 X = 0,634 - 0,0628

X = 19,349

6) Replika keenam

Menit ke - 0
Menit ke - 0

Y=BX+A

X=0

Menit ke - 5

0,249 = 0,02952 X + 0,0628

0,02952 X = 0,249 - 0,0628

X = 6,307

Menit ke - 10

0,349 = 0,02952 X + 0,0628

0,02952 X = 0,349 - 0,0628

X = 9,695

Menit ke - 20

0,507 = 0,02952 X + 0,0628

0,02952 X = 0,507- 0,0628

X = 15,047

Menit ke - 30

0,642 = 0,02952 X + 0,0628

0,02952 X = 0,642 - 0,0628


X = 19,620

Menit ke - 45

0,640 = 0,02952 X + 0,0628

0,02952 X = 0,640 - 0,0628

X = 19,552

Menit ke - 60

0,636 = 0,02952 X + 0,0628

0,02952 X = 0,636 - 0,0628

X = 19,417

b. Faktor koreksi

1) Replikasi pertama

Menit ke - 0

C1 = 0 ppm

Menit ke - 5
 vol.diambil 
C2 = X2 +  vol.media  C1

 5 
= 6,104 +   0
 900 

= 6,104 ppm
Menit ke - 10

 5 
C3 = 10,169 +   0  6,104
 900 

= 10,169 + 0,033

=10,202 ppm

Menit ke 20
-

 5 
C4 = 14,878 +   0  6,104  10,202
 900 

= 14,878 + 0,090

= 14,968 ppm

Menit ke - 0
3

 5 
C5 = 19,756 +   0  6,104  10,202  14,968
 900 

= 19,756 + 0.173

= 19,929 ppm

Menit ke - 5
4
 5 
C6 = 19,654 +   0  6,104  10,202  14,968  19,929
 900 

= 19,654 + 0,284

= 19,938 Ppm

Menit ke - 60

 5 
C7 = 19,349 +   0  6,104  10,202  14,968  19,929  19,938
 900 

= 19,349 + 0,395

=19,744

2) Replikasi kedua

Menit ke - 0

C1 = 0 ppm

Menit ke - 5

 5 
C2 = 6,239 +   0
 900 

= 6,239 ppm

Menit ke - 10

 5 
C3= 10,203 +   0  6,239
 900 

= 10,203 + 0,034
=10,237 ppm

Men t ke - 20
i

 5 
C4= 16,470 +   0  6,239  10,237 
 900 

= 16,470 + 0,091

= 16,561 ppm

Menit ke - 30

 5 
C5= 19,857 +   0  6,239  10,237  16,561
 900 

= 19,857 + 0,183

=20,040 ppm

Men t ke - 45
i

 5 
C6 = 19,688 +   0  6,239  10,237  16,561  20,040
 900 

= 19,688 + 0,294

= 19,982 ppm

Meni ke - 60
t

 5 
C7 = 19,383 +   0  6,239  10,237  16,561  20,040  19,982
 900 
= 19,383 + 0,405

= 19,788 ppm

3) Repl kasi ketiga


i

Menit ke - 0

C1 = 0 ppm

Menit ke 5
-

 5 
C2 = 6,373 +   0
 900 

= 6,373 ppm

Menit ke - 10

 5 
C3 = 8,340 +   0  6,373
 900 

= 8,340 + 0,035

= 8,375 ppm

Menit e - 20
k

 5 
C4 = 16,470 +   0  6,373  8,375
 900 

= 16,470 + 0.081

= 16,551 ppm
Meni ke - 30
t

 5 
C5 = 19,823 +   0  6,373  8,375  16,551
 900 

= 19,823 + 0,173

= 19,996 ppm

Men t ke - 45
i

 5 
C6 = 19,857 +   0  6,373  8,375  16,551  19,996
 900 

= 19,857 + 0,284

= 20,141 ppm

Meni ke - 60
t

 5 
C7 = 19,214 +   0  6,373  8,375  16,551  19,996  20,141
 900 

= 19,214 + 0,396

= 19,610 ppm

4) Repl kasi keempat


i

Meni ke - 0
t
C1 = 0 ppm

Menit ke - 5

 5 
C2 = 5,934 +   0
 900 

= 5,934 ppm

Menit ke - 10

 5 
C3 = 10,304 +   0  5,934
 900 

= 10, 304 + 0,032

= 10,336 ppm

Menit ke - 20

 5 
C4 = 14,979 +   0  5,934  10,336
 900 

= 14,979 + 0,090

= 15, 069 ppm

Menit ke - 30

 5 
C5 = 19,654 +   0  5,934  10,336  15,069
 900 

= 19,654 + 0,174

= 19,828 ppm
Menit ke - 45

 5 
C6= 19,518 +   0  5,934  10,336  15,069  19,828
 900 

= 19,518 + 0,284

=19,802 ppm

Meni ke - 60
t

 5 
C7 = 19,552 +   0  5,934  10,336  15,069  19,828  19,802
 900 

= 19,552 + 0,394

= 19,946 ppm

5) Rep ikasi kelima


l

Meni ke - 0
t

C1 = 0 ppm

Menit ke - 5

 5 
C2 = 6,273 +   0
 900 

= 6,273 ppm

Menit ke - 10

 5 
C3 = 10,135 +   0  6,273
 900 
= 10,135 + 0,034

= 10,169 ppm

Menit ke - 20

 5 
C4 = 15,149 +   0  6,273  10,169
 900 

= 15,149 + 0,091

= 15, 240 ppm

Menit ke - 30

 5 
C5 = 19,688 +   0  6,273  10,169  15,240
 900 

=19,688 + 0,176

=19,864 ppm

Menit ke - 45

 5 
C6 = 19,552 +   0  6,273  10,169  15,240  19,864
 900 

= 19,552 + 0,286

= 19,838 ppm

Meni ke - 60
t
 5 
C7 = 19,349 +   0  6,273  10,169  15,240  19,864  19,838
 900 

= 19,349 + 0,396

=19,745 ppm

6) Rep ikasi keenam


l

Menit ke - 0

C1 = 0 ppm

Menit ke - 5

 5 
C2 = 6,307 +   0
 900 

= 6,307 ppm

Menit ke - 10

 5 
C3 = 9,695 +   0  6,307
 900 

= 9,695 + 0,035

=9,730 ppm

Menit ke - 20

 5 
C4 = 15,047 +   0  6,307  9,730
 900 

= 15,047 + 0,089

= 15,136 ppm
Menit ke - 30

 5 
C5 = 19,620 +   0  6,307  9,730  15,136
 900 

= 19,620 + 0,173

= 19,793 ppm

Menit ke - 45

 5 
C6 = 19,552 +   0  6,307  9,730  15,136  19,793
 900 

= 19,552 + 0,173

=19,725 ppm

Meni ke - 60
t

 5 
C7 = 19,470 +   0  6,307  9,730  15,136  19,793  19,725
 900 

= 19,470 + 0,392

= 19,862 ppm

c. % terdisolusi

faktorkoreksi
% terdisolusi = 100%
lar .uji
50mg 50mg
Larutan uji = =
900 0,9 L

= 55,555 ppm

1) Replika pertama

Menit ke - 0

0 ppm
% terdisolusi = 100%
55,555

=0%

Menit ke - 5

6,104 ppm
% terdisolusi = 100%
55,555 ppm

= 10,987%

Menit ke - 10

10,202 ppm
% terdisolusi = 100%
55,555 ppm

= 18,363%

Menit ke - 20

14,968 ppm
% terdisolusi = 100%
55,555 ppm

=26,942%

Menit ke - 30

19,929 ppm
% terdisolusi = 100%
55,555 ppm
= 35,872 %

Menit ke - 45

19,938 ppm
% terdisolusi = 100%
55,555 ppm

= 35,888%

Menit ke - 60

19,744 ppm
% terdisolusi = 100%
55,555 ppm

= 35,539 %

2) Replika kedua

Menit ke - 0

0 ppm
% terdisolusi = 100%
55,555 ppm

=0%

Menit ke - 5

6,239 ppm
% terdisolusi = 100%
55,555 ppm

= 11.230%

Menit ke - 10

10,237 ppm
% terdisolu = 100%
si 55,555 ppm

= 18,426%

Menit ke - 20
16,561 ppm
% terdisolusi = 100%
55,555 ppm

=29,810%

Menit ke - 30

20,040 ppm
% terdisolusi = 100%
55,555 ppm

= 36.072 %

Menit ke - 45

19,982 ppm
% terdisolusi = 100%
55,555 ppm

= 35,967%

Menit ke - 60

19,788 ppm
% terdisolusi = 100%
55,555 ppm

= 35,618 %

3) Replika ketiga

Menit ke - 0

0 ppm
% terdisolusi = 100%
55,555

=0%

Menit ke - 5
6,373 ppm
% terdisolusi = 100%
55,555 ppm

= 11,471%

Menit ke - 10

8,375 ppm
% terdisolus = 100%
i 55,555 ppm

= 15,075%

Menit ke - 20

16,551 ppm
% terdisolusi = 100%
55,555 ppm

=29,792%

Menit ke - 30

19,996 ppm
% terdisolusi = 100%
55,555 ppm

= 35,993 %

Menit ke - 45

20,141 ppm
% terdisolusi = 100%
55,555 ppm

= 36,254%

Menit ke - 60

19,610 ppm
% terdisolusi = 100%
55,555 ppm

= 35,298%
4) Replika keempat

Menit ke - 0

0 ppm
% terdisolusi = 100%
55,555

=0%

Menit ke - 5

5,934 ppm
% terdisolusi = 100%
55,555 ppm

= 10,681%

Menit ke - 10

10,336 ppm
% terdisolus = 100%
i 55,555 ppm

= 18,604%

Menit ke - 20

15,069 ppm
% terdisolusi = 100%
55,555 ppm

=27,124%

Menit ke - 30

19,828 ppm
% terdisolusi = 100%
55,555 ppm

= 35,690 %

Menit ke - 45
19,802 ppm
% terdisolusi = 100%
55,555 ppm

= 35,643%

Menit ke - 60

19,946 ppm
% terdisolusi = 100%
55,555 ppm

= 35,903%

5) Replika kelima

Menit ke - 0

0 ppm
% terdisolusi = 100%
55,555

=0%

Menit ke - 5

6,273 ppm
% terdisolusi = 100%
55,555 ppm

= 11,291%

Menit ke - 10

10,169 ppm
% terdisolus = 100%
i 55,555 ppm

= 18,304%

Menit ke - 20
15,240 ppm
% terdisolusi = 100%
55,555 ppm

=27,432%

Menit ke - 30

19,864 ppm
% terdisolusi = 100%
55,555 ppm

= 35,755 %

Menit ke - 45

19,838 ppm
% terdisolusi = 100%
55,555 ppm

= 35,708%

Menit ke - 60

19,745 ppm
% terdisolusi = 100%
55,555 ppm

= 35,541 %

6) Replika keenam

Menit ke - 0

0 ppm
% terdisolusi = 100%
55,555

=0%

Menit ke - 5
6,307 ppm
% terdisolusi = 100%
55,555 ppm

= 11,352%

Menit ke - 10

9,730 ppm
% terdisolus = 100%
i 55,555 ppm

= 17,514%

Menit ke - 20

15,136 ppm
% terdisolusi = 100%
55,555 ppm

=27,245%

Menit ke - 30

19,793 ppm
% terdisolusi = 100%
55,555 ppm

= 35,627 %

Menit ke - 45

19,725 ppm
% terdisolusi = 100%
55,555 ppm

= 35,505%

Menit ke - 60

19,862 ppm
% terdisolusi = 100%
55,555 ppm

= 35,751%

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