Scribd Logo
Upload

Welcome to Scribd!

  • 32 views

    Nucleic Acids: Experiment # 12

    Uploaded by

    Princes Viña Dalisay Paulo
    This document discusses nucleic acids and their structure. Nucleic acids are polymers made up of nucleotide monomer units, which each contain a pentose sugar, phosphate group, and nitrogenous base. The two main nucleic acids are DNA and RNA. The document also examines positive test results for purine, pentose, deoxyribose, and phosphorus in nucleic acid samples. Additionally, it provides an overview of sickle cell disease, including that it affects hemoglobin in red blood cells and causes them to take on a sickle shape, leading to anemia and other issues. A wrong nucleotide inserted during DNA replication can result in a mutation, which may have no effect, alter cell function, or rarely cause cell death.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    Nucleic Acids: Experiment # 12

    Uploaded by

    Princes Viña Dalisay Paulo
    32 views4 pages
    This document discusses nucleic acids and their structure. Nucleic acids are polymers made up of nucleotide monomer units, which each contain a pentose sugar, phosphate group, and nitrogenous base. The two main nucleic acids are DNA and RNA. The document also examines positive test results for purine, pentose, deoxyribose, and phosphorus in nucleic acid samples. Additionally, it provides an overview of sickle cell disease, including that it affects hemoglobin in red blood cells and causes them to take on a sickle shape, leading to anemia and other issues. A wrong nucleotide inserted during DNA replication can result in a mutation, which may have no effect, alter cell function, or rarely cause cell death.

    Original Description:

    Original Title

    NUCLEIC-ACIDS

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    This document discusses nucleic acids and their structure. Nucleic acids are polymers made up of nucleotide monomer units, which each contain a pentose sugar, phosphate group, and nitrogenous base. The two main nucleic acids are DNA and RNA. The document also examines positive test results for purine, pentose, deoxyribose, and phosphorus in nucleic acid samples. Additionally, it provides an overview of sickle cell disease, including that it affects hemoglobin in red blood cells and causes them to take on a sickle shape, leading to anemia and other issues. A wrong nucleotide inserted during DNA replication can result in a mutation, which may have no effect, alter cell function, or rarely cause cell death.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    32 views4 pages

    Nucleic Acids: Experiment # 12

    Uploaded by

    Princes Viña Dalisay Paulo
    This document discusses nucleic acids and their structure. Nucleic acids are polymers made up of nucleotide monomer units, which each contain a pentose sugar, phosphate group, and nitrogenous base. The two main nucleic acids are DNA and RNA. The document also examines positive test results for purine, pentose, deoxyribose, and phosphorus in nucleic acid samples. Additionally, it provides an overview of sickle cell disease, including that it affects hemoglobin in red blood cells and causes them to take on a sickle shape, leading to anemia and other issues. A wrong nucleotide inserted during DNA replication can result in a mutation, which may have no effect, alter cell function, or rarely cause cell death.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 4

    NUCLEIC ACIDS

    Experiment # 12

    GROUP 2
    Aranjuez, Hannah Suzane
    Camus, Rochelle Mae
    Jamero, Jhon Rico
    Ligutom, Lester
    Mapilindo, Mar-a
    Nucleic Acid
    -is a polymer in which the monomer units are nucleotides.

    Nucleotide
    -building blocks of nucleic acid
    -is a three-subunit molecule in which a pentose sugar is bonded to both a
    phosphate group and a nitrogen-containing heterocyclic base.

    Base

    Sugar Phosphate

     Two types of nucleic acid found in the cells of higher organisms:


     Deoxyribonucleic Acid (DNA)
     Ribonucleic Acid (RNA)




     Positive results for the following substances.

    Substances Test/ Reagents Indication of Positive Result


    Purine Silver Nitrate and Ammonia Formation of foamy
    Solution gelatinous substance
    Pentose Bluish color and precipitate
    Bial’s Test
    formation
    Deoxyribose Diphenylamine Blue colored liquid solution
    Phosphorous Ammonium
    Heptamolybdate and Yellow precipitate
    Sulfuric Acid

    SICKLE CELL DISEASE


    Sickle cell disease is a group of disorders that affects hemoglobin, the molecule
    in red blood cells that delivers oxygen to cells throughout the body. People with this
    disorder have atypical hemoglobin molecules called hemoglobin S, which can distort red
    blood cells into a sickle, or crescent, shape.
     Cause
    The signs and symptoms of sickle cell disease are caused by the sickling of red
    blood cells. When red blood cells sickle, they break down prematurely, which can
    lead to anemia. Anemia can cause shortness of breath, fatigue, and delayed growth
    and development in children. The rapid breakdown of red blood cells may also
    cause yellowing of the eyes and skin, which are signs of jaundice.

     Shape
    The shape of a red blood cell is a biconcave disk with a flattened center - in other
    words, both faces of the disc have shallow bowl-like indentations (a red blood cell
    looks like a donut). While in sickle cell anemia, the red blood cells become rigid and
    sticky and are shaped like sickles or crescent moons Production of red blood cells is
    controlled by erythropoietin, a hormone produced primarily by the kidneys.
     Ability to carry oxygen
    Sickle cell anemia inhibits the ability of haemoglobin in red blood cells to
    carry oygen.

    Insertion of wrong nucleotide into a DNA code group could result in?
    Mutation occurs when a “wrong” nucleotide is inserted during DNA replication.
    When this happened in a protein coding-gene, it could have no effect on the cell that
    bears it, it could change the cell’s function, or rarely cause the cell to die, which is no
    big deal to you because you have 37 trillion of them.

    You might also like