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    Acute Rheumatic Fever

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    Michelle Vera Gabun
    Acute rheumatic fever is an inflammatory disease that can affect the heart, joints, nervous system, and skin after a streptococcal throat infection. It is caused by group A beta-hemolytic streptococcus. Symptoms include carditis, polyarthritis, chorea, erythema marginatum, and subcutaneous nodules. Treatment focuses on relieving symptoms with salicylates, rest, and benzathine penicillin injections to prevent recurrence. Long term complications are usually cardiac in nature.

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    Acute Rheumatic Fever

    Uploaded by

    Michelle Vera Gabun
    20 views1 page
    Acute rheumatic fever is an inflammatory disease that can affect the heart, joints, nervous system, and skin after a streptococcal throat infection. It is caused by group A beta-hemolytic streptococcus. Symptoms include carditis, polyarthritis, chorea, erythema marginatum, and subcutaneous nodules. Treatment focuses on relieving symptoms with salicylates, rest, and benzathine penicillin injections to prevent recurrence. Long term complications are usually cardiac in nature.

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    Acute-Rheumatic-Fever

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    Acute rheumatic fever is an inflammatory disease that can affect the heart, joints, nervous system, and skin after a streptococcal throat infection. It is caused by group A beta-hemolytic streptococcus. Symptoms include carditis, polyarthritis, chorea, erythema marginatum, and subcutaneous nodules. Treatment focuses on relieving symptoms with salicylates, rest, and benzathine penicillin injections to prevent recurrence. Long term complications are usually cardiac in nature.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    20 views1 page

    Acute Rheumatic Fever

    Uploaded by

    Michelle Vera Gabun
    Acute rheumatic fever is an inflammatory disease that can affect the heart, joints, nervous system, and skin after a streptococcal throat infection. It is caused by group A beta-hemolytic streptococcus. Symptoms include carditis, polyarthritis, chorea, erythema marginatum, and subcutaneous nodules. Treatment focuses on relieving symptoms with salicylates, rest, and benzathine penicillin injections to prevent recurrence. Long term complications are usually cardiac in nature.

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    Acute Rheumatic Fever Pathophysiology

    Definition: An inflammatory disease of the heart, joints,


    central nervous system and subcutaneous tissues that
    develops after a nasopharyngeal infection by one of the
    group A beta-hemolytic streptococci.

    Etiology: Group A beta-hemolytic streptococci

    Epidemiology (PPS, 2014)


     12.6% in URTI
     58.7 with skin infection
     2.6-4.1% asymptomatic
     Peak incidence at 10-12 years old
     Increasing frequency of early onset of carditis
    and valvulitis among children

    Clinical Manifestations
     Major
    o Carditis
    o Polyarthritis
    o Chorea
    o Erythema marginatum
    o Subcutaneous nodules
     Minor
    o Clinical Findings
     Arthralgia
     Fever
    o Laboratory Findings Treatment
     Elevated acute phase-reactants  Therapy for acute rheumatic fever is
     Elevated c-reactive protein symptomatic.
     Prolonged PR interval  Salicylate therapy for joint inflammation and
    fever
    Supportive evidence of antecedent group A  Restriction of physical activity until rheumatic
    streptococcal infection process has become quiescent.
    1. Positive throat culture or rapid streptococcal  All patients should receive benzathine penicillin.
    antigen test
    2. Elevated or rising streptococcal antibody titer Complications
     The arthritis and chorea of acute rheumatic
    ***If supported by evidence of preceding group A fever resolve completely without sequelae.
    streptococcal infection, the presence of TWO MAJOR or  The long-standing sequelae of rheumatic fever
    of ONE MAJOR AND TWO MINOR manifestations are usually limited to the heart.
    indicates a high probability of acute rheumatic fever.
    Prevention
    Diagnosis  Penicillin prophylaxis is well established in its
     ERS, CRP, ASO titer ability to prevent recurrent attacks.
     CXR
     2D echo
     Throat culture

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