DRUG STUDY

DRUG CLASSIFICATI THERAPEUTIC INDICATION CONTRAINDICATI ADVERSE EFFECTS NURSING RESPONSIBILITY

misoprostol Prostaglandin A synthetic ● Prevention of NSAID ● Contraindicated ● GI: Nausea, ●Give to patients at high risk for developing
NSAID-induced gastric ulcers; give for the
(mye soe prost’ prostaglandin E1 (including aspirin)- with history of diarrhea, abdominal full term of the NSAID use.
ole) analogue; inhibits induced gastric ulcers in allergy to pain,
gastric acid secretion patients at high prostaglandins; flatulence, vomiting, ●Arrange for oral and written explanation of
the risks to pregnancy; appropriate contraceptive
Brand Name: and increases risk of complications pregnancy dyspepsia, measures must be taken; begin therapy
Cytotec bicarbonate from a gastric ulcer (abortifacient; constipation on the second or third day of a normal
and mucus (the elderly; patients with advise women of ● GU: Miscarriage, menstrual period.
Pregnancy production, concomitant debilitating childbearing age in excessive bleeding,
category x protecting the lining disease, history of ulcers) written spotting,
of the stomach. ● With mifepristone as and oral form of use, cramping,
an abortifacient (see have a negative hypermenorrhea,
mifepristone) serum pregnancy test menstrual
● Unlabeled use: within 2 wk prior to disorders,
Appears effective in therapy, provide dysmenorrhea
treating contraceptives, and ● Other: Headache
but not preventing begin
duodenal ulcers in therapy on the second
patients or third day of
unresponsive to the next normal
histamine-2 antagonists; menstrual period);
cervical ripening and lactation.
labor induction; ● Use cautiously in
postpartum hemorrhage; the elderly, and with
chronic idiopathic renal
constipation impairment, duodenal
ulcers.
 DRUG STUDY

DRUG CLASSIFICATI THERAPEUTIC INDICATION CONTRAINDICATI ADVERSE EFFECTS NURSING RESPONSIBILITY

Oxytocin Hormone Synthetic form of an ● Antepartum: To initiate ● Contraindicated ● CV: Cardiac ● Ensure fetal position and size and
Oxytocic endogenous or improve uterine with significant arrhythmias, PVCs, absence
(ox i toe’ sin) hormone contractions to achieve cephalopelvic hypertension, of complications that are
produced in the early vaginal delivery; disproportion, subarachnoid contraindicated
Brand Name: hypothalamus and stimulation or unfavorable fetal hemorrhage with oxytocin before therapy.
stored in reinforcement of labor positions ● Fetal effects: Fetal ●Ensure continuous observation
Pitocin the posterior in selected cases of or presentations, bradycardia, neonatal of patient receiving IV oxytocin for
pituitary; stimulates uterine inertia; obstetric emergencies jaundice, low Apgar induction
the uterus, management that favor surgical scores or stimulation of labor; fetal
pregnancy especially the gravid of inevitable or intervention, ● GI: Nausea, monitoring
category x uterus just before incomplete abortion; prolonged vomiting is preferred. A physician should be
parturition, second trimester use in severe ● GU: Postpartum immediately available to deal with
and causes abortion. toxemia, uterine hemorrhage, uterine complications
myoepithelium of ● Postpartum: To inertia, hypertonic rupture, if they arise.
the lacteal produce uterine uterine patterns, pelvic hematoma, ● Regulate rate of oxytocin delivery
glands to contract, contractions induction or uterine hypertonicity, to establish
which results in milk during the third stage of augmentation spasm, tetanic uterine contractions that are similar
ejection labor and to control of labor when vaginal contraction, rupture to
in lactating women. postpartum bleeding or delivery is of the uterus with normal labor; monitor rate and
hemorrhage contraindicated, excessive dosage or strength of
● Lactation deficiency previous cesarean hypersensitivity contractions; discontinue drug and
● Unlabeled uses: To section, ● Hypersensitivity: notify
evaluate fetal distress pregnancy. Anaphylactic physician at any sign of uterine
(oxytocin challenge test), ● Use cautiously with reaction hyperactivity
treatment of breast renal impairment. ● Other: Maternal or spasm.
engorgement and fetal deaths when
used
to induce labor or in
first or second stages
of labor;
afibrinogenemia;
severe
water intoxication
with seizures and
coma, maternal death
(associated with
slow oxytocin infusion
over 24 hr; oxytocin
has antidiuretic
effects)
 DRUG STUDY

Nomenclature Mechanism of action Contraindication Indication Adverse Effect Nursing

Generic Name: Bacterial: inhibits Allergy to cephalosporins Lower respiratory tract infections cause CNS: headache, dizziness, Assess for the pt.
Ceftriaxone synthesis of bacterial or penicilins, renal S.pneumonia, lethargy, paresthesias . history: liver and
cell wall, causing cell failure, lactation and S.ureas,Klebsiella,H.influenza, E. coli,P. kidney dysfunction,
death. pregnancy mirabilis, E.aerogens ,Seratia GI: nausea, vomiting, lactation, pregnancy
marcessens, Haemophilus parainfluenza, diarrhea, anorexia, abdominal
Brand Name: pain, flatulence, Physical: skin, status,
streptococcus (excluding enterococci)
Rocephin pseudomembranous colitis, liver and kidney
liver toxicity function test, culture of
affected area
GU: nephrotoxicity sensitivity teeest
Classification:
Hematologic: bone marrow
Third- generation depression; decrease WBC,
Cephalosporin decrase platelets, decrease
HCT

Hypersensitivity: Ranging
from rash to fever to
anaphylaxis,
serum,sickess,reaction