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    Differential Diagnosis: Disease/Condition Differentiating Signs/Symptoms Differentiating Tests

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    Lisdasari
    This document summarizes several diseases and conditions that can cause portal hypertension by listing their differentiating signs and symptoms as well as tests. It includes conditions such as constrictive pericarditis, Budd-Chiari syndrome, portal vein thrombosis, splenic vein thrombosis, inferior vena cava obstruction, schistosomiasis, sarcoidosis, nodular regenerative hyperplasia, idiopathic portal hypertension, and certain toxicities. The document aids differential diagnosis by highlighting distinguishing clinical features and test results for each condition.

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    Differential Diagnosis: Disease/Condition Differentiating Signs/Symptoms Differentiating Tests

    Uploaded by

    Lisdasari
    97 views4 pages
    This document summarizes several diseases and conditions that can cause portal hypertension by listing their differentiating signs and symptoms as well as tests. It includes conditions such as constrictive pericarditis, Budd-Chiari syndrome, portal vein thrombosis, splenic vein thrombosis, inferior vena cava obstruction, schistosomiasis, sarcoidosis, nodular regenerative hyperplasia, idiopathic portal hypertension, and certain toxicities. The document aids differential diagnosis by highlighting distinguishing clinical features and test results for each condition.

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    Differential Diagnosis

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    This document summarizes several diseases and conditions that can cause portal hypertension by listing their differentiating signs and symptoms as well as tests. It includes conditions such as constrictive pericarditis, Budd-Chiari syndrome, portal vein thrombosis, splenic vein thrombosis, inferior vena cava obstruction, schistosomiasis, sarcoidosis, nodular regenerative hyperplasia, idiopathic portal hypertension, and certain toxicities. The document aids differential diagnosis by highlighting distinguishing clinical features and test results for each condition.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    97 views4 pages

    Differential Diagnosis: Disease/Condition Differentiating Signs/Symptoms Differentiating Tests

    Uploaded by

    Lisdasari
    This document summarizes several diseases and conditions that can cause portal hypertension by listing their differentiating signs and symptoms as well as tests. It includes conditions such as constrictive pericarditis, Budd-Chiari syndrome, portal vein thrombosis, splenic vein thrombosis, inferior vena cava obstruction, schistosomiasis, sarcoidosis, nodular regenerative hyperplasia, idiopathic portal hypertension, and certain toxicities. The document aids differential diagnosis by highlighting distinguishing clinical features and test results for each condition.

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    © All Rights Reserved
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    of 4

    Differential Diagnosis

    Disease/Condition Differentiating Signs/Symptoms Differentiating Tests


    Constrictive Elevated jugular venous pressure, ECG: tachycardia, atrial fibrillation, low-
    pericarditis tachycardia, and atrial fibrillation. voltage QRS complexes, T-wave
    abnormalities.
    Heart sounds: quiet, third heart sound
    (ventricular knock) present. Doppler ultrasound: ventricular filling
    abnormalities.

    Budd-Chiari Abdominal pain, diarrhea, and Doppler ultrasound and abdominal CT:
    syndrome progressively worsening ascites. absence of hepatic vein filling.
    Abdominal CT: rapid contrast clearing of
    caudate lobe.

    Portal vein Signs and symptoms of the underlying Magnetic resonance (indirect) or direct
    thrombosis cause such as acute pancreatitis angiography: normal hepatic venous
    (severe upper abdominal pain radiating pressure gradient (measure of portal
    through to the back, vomiting, absent pressure).
    bowel sounds, pyrexia, hypovolemic
    Doppler ultrasound and abdominal CT: portal
    shock, skin discoloration periumbilically
    vein filling defect, absence of flow in the
    [Cullen sign] and in the flanks [Grey
    portal vein.
    Turner sign]), ascending cholangitis
    (pyrexia, malaise, rigors, right upper
    quadrant pain, jaundice, dark urine,
    and pale stools), or abdominal sepsis
    (pyrexia, abdominal pain, signs of
    peritonism).

    Splenic vein Signs and symptoms of pancreatitis: Abdominal ultrasound and CT: evidence of
    thrombosis severe upper abdominal pain radiating splenic vein thrombosis.
    through to the back, vomiting, absent
    Magnetic resonance (indirect) or direct
    bowel sounds, pyrexia, hypovolemic
    angiography: normal hepatic venous
    shock, and skin discoloration
    pressure gradient (measure of portal
    periumbilically (Cullen sign) and in the
    pressure).
    flanks (Grey Turner sign) in acute
    Disease/Condition Differentiating Signs/Symptoms Differentiating Tests
    pancreatitis; nonspecific abdominal
    pain exacerbated by eating, diarrhea,
    steatorrhea, weight loss, and mild
    pyrexia in chronic pancreatitis.

    Inferior vena cava Signs and symptoms of renal cell Abdominal ultrasound and CT: evidence of
    (IVC) obstruction carcinoma: classic triad of hematuria, IVC obstruction.
    flank pain, and flank/abdominal mass
    with weight loss and hypertension.

    Schistosomiasis History of travel to endemic areas. Magnetic resonance (indirect) or direct


    angiography: normal hepatic venous
    Constitutional symptoms of febrile
    pressure gradient (measure of portal
    illness: malaise, rigors, sweating,
    pressure).
    weight loss, anorexia, vomiting,
    diarrhea, headache, muscular aches
    and weakness, and abdominal pain.
    Signs of febrile illness: urticarial rash,
    pyrexia, and lymphadenopathy.

    Sarcoidosis Lung involvement: dry cough and Chest x-ray findings are dependent on the
    dyspnea. stage of disease progression: hilar
    lymphadenopathy, diffuse reticulonodular
    Skin involvement: altered pigmentation
    shadowing (parenchymal disease), and
    (hypo- or hyperpigmented);
    upper lobe fibrosis.
    maculopapular skin lesions on face,
    back, and extremities; and erythema Liver biopsy: non-necrotizing/caseating
    nodosum on legs. granulomas.
    Eye involvement: anterior or posterior
    uveitis, dry eyes (sicca), and
    glaucoma.

    Nodular No differentiating signs and symptoms. Liver biopsy: small regenerative nodules with
    regenerative minimal or no fibrosis on reticulin staining.
    hyperplasia
    Disease/Condition Differentiating Signs/Symptoms Differentiating Tests
    Idiopathic portal No differentiating signs and symptoms. Liver biopsy: no evidence of cirrhosis.
    hypertension
    (hepatoportal
    sclerosis)

    Vitamin A No differentiating signs and symptoms. History generally reveals exposure.


    intoxication, arsenic,
    and vinyl chloride
    toxicity

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