Salbutamol: A Drug Study On

A Drug Study on
SALBUTAMOL
In partial fulfillment of the

Requirements in NCM 209- RLE
PEDIATRIC ROOM NURSING ROTATION
Submitted to:
Ma’am Weniegin Ruth Dullin, RN, MN
Submitted by:
Aliana Nicole B. Emuy, St. N.

SUBGROUP 4 - BSN 2J
January 25, 2021

GENERIC NAME:
Salbutamol
BRAND NAME:
Proventil, Vospira ER, Accuneb, Ventodisk, Ventolin
PREGNANCY CATERGORY: C
USES: Treatment or prevention of bronchospasm due to reversible obstructive airway disease, prevention of exercise-
induced bronchospasm.
INDICATION
To prevent exercise-induced bronchospasm and to treat or prevent bronchospasms in patient with reversible
obstructive airway disease or acute bronchospatic attack.
CONTRAINDICATIONS
Hypersensitivity to albuterol. Severe hypersensitivity to milk protein (powder for inhalation).
Cautions: Hypertension, cardiovascular disease, hyperthyroidism, diabetes, HF, convulsive disorders, glaucoma,
hypokalemia, arrhythmias.
CLASSIFICATION
PHARMACOTHERAPEUTIC: Sympathomimetic (adrenergic anogist).
CLINICAL: Bronchodilator.
ORDERED DOSE AND FREQUENCY
Acute Bronchospasm, Exacerbation of Asthma
ROUTE OF ADMINISTRATION DOSE FREQUENCY
INHALATION ADULTS, ELDERLY, CHILDREN q20min up to 4 hrs, then q1–4h as

OLDER THAN12 YRS: needed.
(ACUTE,SEVERE): 4 – 8 puffs
CHILDREN 12 YRS AND YOUNGER: q20min

(Acute, Severe): 4 – 8 puffs for 3 doses, then q1–4h as needed.
NEBULIZATION ADULTS, ELDERLY, CHILDREN

OLDER THAN12 YRS:
(ACUTE,SEVERE):
q20min for 3 doses
2.5 – 5 mg
q1–4h
2.5 – 10 mg continuously
10 – 15 mg/hr
Chronic Bronchospasm
PO ADULTS, CHILDREN OLDER THAN 3 – 4 times/day

12 YRS: 2–4 mg
Maximum: 8 mg 4 times/day
3 – 4 times/day
ELDERLY: 2 mg
4 times/day
Maximum: 8 mg
3 – 4 times/day
CHILDREN 6–12 YRS: 2 mg Per day
Maximum: 24 mg
CHILDREN 2–5 YRS: 0.1–0.2 3 times/day

mg/kg/dose
Maximum: 24 mg 3 times/day
PO: (EXTENDED RELEASE) ADULTS, CHILDREN OLDER THAN q12h

12 YRS: 4– 8 mg
Maximum: 32 mg/day
CHILDREN 6–12 YRS: 4 mg q12h.

Maximum: 24 mg/day.
NEBULIZATION ADULTS, ELDERLY, CHILDREN 12 3–4 times/day as needed.

YRS AND OLDER: 2.5 mg
CHILDREN 2–11 YRS: 0.63–1.25 mg 3–4 times/day as needed.

INHALATION ADULTS, ELDERLY, CHILDREN: 2 q4–6h as needed.
puffs
Exercise-Induced Bronchospasm
INHALATION ADULTS, ELDERLY, CHILDREN 5 5 minutes before exercise

YRS AND OLDER: 2 puffs
5 minutes before exercise

CHILDREN 4 YRS AND YOUNGER:
1–2 puffs
Dosage in Renal/Hepatic Impairment
No Dose Adjustment
MODE OF ACTION
Stimulates beta2 -adrenergic receptors in lungs, resulting in relaxation of bronchial smooth muscle. Therapeutic Effect:
Relieves bronchospasm and reduces airway resistance.
SIDE EFFECTS
Frequent 27% - 4% : Occasional 3% - 2%: Rare:
Headache, restlessness, Insomnia, asthenia, altered taste. Drowsiness, diarrhea, dry mouth,
nervousness, tremors, nausea, flushing, diaphoresis, anorexia.
dizziness, throat dryness and irritation, Inhalation: Dry, irritated mouth or
pharyngitis, B/P changes including throat; cough, bronchial irritation.
hypertension, heartburn, transient
wheezing.
ADVERSE EFFECTS/ TOXIC REACTIONS
Excessive sympathomimetic stimulation may produce palpitations, ectopy, tachycardia, chest pain, slight increase in
B/P followed by substantial decrease, chills, diaphoresis, blanching of skin.
Too-frequent or excessive use may lead to decreased bronchodilating effectiveness and severe, paradoxical
bronchoconstriction.
DRUG INTERACTION
DRUG - Beta-blockers (e.g., carvedilol, labetalol, metoprolol)

antagonize effects. May produce bronchospasm.
Atomoxetine, MAIOs, tricyclic antidepressants (e.g.,
amitriptyline, doxepin) may potentiate cardiovascular
effects. May increase effects of loop diuretics (e.g.,
furosemide) (produce hypokalemia),
sympathomimetics (increase CNS stimulation).
HERBAL - St. John’s wort may decrease level/effects. Ephedra,

yohimbe may cause CNS stimulation.
FOOD - None Known.
LAB VALUES - May increase blood glucose level. May decrease serum
potassium level.
NURSING RESPONSIBILITIES
BASELINE ASSESSMENT
1. Assess lung sounds, pulse, B/P, color, characteristics of sputum noted.

2. Offer emotional support (high incidence of anxiety due to difficulty in breathing and
sympathomimetic response to drug).
INTERVENTION/EVALUATION
1. Check and verify with doctor’s order and Kardex.

2. Observe rights in medication administration such as giving the right drug to the right patient using the right route
and at the right time.
3. Monitor rate, depth, rhythm, type of respiration; quality and rate of pulse; EKG;
serum potassium, glucose; ABG determinations.
4. Assess lung sounds for wheezing (bronchoconstriction), rales.
5. Administer accurately because adverse reactions and tolerance might occur.
6. Auscultate lungs for presence of adventitious breath sounds that may signal pulmonary edema, airway resistance
or bronchospasm.
7. Inspect client’s nail bed and oral mucosa for pallor.
PATIENT/FAMILY TEACHING
1. Follow guidelines for proper use of inhaler.

2. A health care provider will show you know to properly prepare and use your
medication. You must demonstrate correct preparation and injection techniques before using medication.
3. Increase fluid intake (decreases lung secretion viscosity)..
4. Do not take more than 2 inhalations at any one time (excessive use may produce paradoxical bronchoconstriction
or decreased bronchodilating effect).
5. Rinsing mouth with water immediately after inhalation may prevent mouth/throat dryness.
6. Avoid excessive use of caffeine derivatives (chocolate, coffee, tea, cola, cocoa).
BIBLIOGRAPHY
Kizior, R. J. (2019). Saunders Nursing Drug Handbook 2019. St. Louis: Elsevier. 233-237.
Nurse’s Drug Handbook. (2018). 17th edn. USA: Jones & Bartlett Learning.
Salbutamol Drug Study. (2018, May 24.) Retrieved from https://rnspeak.com/salbutamol-drug-study/

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A Drug Study on

In partial fulfillment of the

Ma’am Weniegin Ruth Dullin, RN, MN

Aliana Nicole B. Emuy, St. N.

January 25, 2021

Hypersensitivity to albuterol. Severe hypersensitivity to milk protein (powder for inhalation).

PHARMACOTHERAPEUTIC: Sympathomimetic (adrenergic anogist).

ORDERED DOSE AND FREQUENCY

Acute Bronchospasm, Exacerbation of Asthma

ROUTE OF ADMINISTRATION DOSE FREQUENCY

INHALATION ADULTS, ELDERLY, CHILDREN q20min up to 4 hrs, then q1–4h as

CHILDREN 12 YRS AND YOUNGER: q20min

NEBULIZATION ADULTS, ELDERLY, CHILDREN

ROUTE OF ADMINISTRATION DOSE FREQUENCY

PO ADULTS, CHILDREN OLDER THAN 3 – 4 times/day

CHILDREN 2–5 YRS: 0.1–0.2 3 times/day

PO: (EXTENDED RELEASE) ADULTS, CHILDREN OLDER THAN q12h

CHILDREN 6–12 YRS: 4 mg q12h.

NEBULIZATION ADULTS, ELDERLY, CHILDREN 12 3–4 times/day as needed.

CHILDREN 2–11 YRS: 0.63–1.25 mg 3–4 times/day as needed.

ROUTE OF ADMINISTRATION DOSE FREQUENCY

INHALATION ADULTS, ELDERLY, CHILDREN 5 5 minutes before exercise

5 minutes before exercise

Dosage in Renal/Hepatic Impairment

Frequent 27% - 4% : Occasional 3% - 2%: Rare:

ADVERSE EFFECTS/ TOXIC REACTIONS

DRUG - Beta-blockers (e.g., carvedilol, labetalol, metoprolol)

HERBAL - St. John’s wort may decrease level/effects. Ephedra,

FOOD - None Known.

1. Assess lung sounds, pulse, B/P, color, characteristics of sputum noted.

1. Check and verify with doctor’s order and Kardex.

1. Follow guidelines for proper use of inhaler.

Salbutamol Drug Study. (2018, May 24.) Retrieved from https://rnspeak.com/salbutamol-drug-study/

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