Sample Paper For M. Phil Admission Preparation
Sample Paper For M. Phil Admission Preparation
Sample Paper For M. Phil Admission Preparation
DEPARTMENT OF CHEMISTRY
SSemester Dated:
Note: Attempt all the questions. All questions carry equal marks.
a) Ethyl 3-(5-oxocyclopent-1-en-1-yl)propanoate
b) Dicyclohexylcarbodiimide
c) Ninhydrin
d) Salicylaldehyde
e) DMAP
2) Arrange the following carboxylic acid in increasing order of acidity starting from weak acid
1
(a) Suggest the products of the following reactions with detailed mechanism? (2)
O-
S+
H3C CH3 E2 reaction
Br ?
?
OH Br2, H2O
b) How would you carry out the following transformations? More than one step may be needed
(3)
OH
H3CO OCH3
COOH
OH
Q.4.
(a) What is meant by the term “Thermodynamic and kinetic control”? Give one example. (2+0.5)
Plan a synthesis of the Pfizer anti-fungal agent fluconazole using a disconnection approach. (5)
N N
OH
N N
N N
F
F
Q. 6: In the following set of questions, encircle the most appropriate option: (5x1)
3. The correct order for the basic features of a mass spectrometer is:
a) acceleration, deflection, detection, ionization
b) ionization, acceleration, deflection, detection
c) acceleration, ionization, deflection, detection
d) acceleration, deflection, ionization, detection
4. In 1H NMR, the most highly shielded protons which are typically encountered are:
a) Six peaks
b) Three peaks
c) Four peaks
d) Two peaks
Q. 7: Appropriately answer the following question.
Terpenoids are biosynthetic combination of isoprene units. Identify the isoprene units in the
following terpenoids by encircling each isoprene unit. 1
i) α-Pinene
ii) Menthol
a) Write the basic core structure for the following class of compounds. 2
i. Coumarin
ii. Flavonoid
b) The fatty acid can be conveniently represented by lipid numbers. Identify the lipid number
for the following fatty acids. 1