Drug Study - Aspirin

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DRUG STUDY

DRUGS ORDER NURSING


(GENERIC, / MECHANISM OF ACTION INDICATIONS CONTRAINDICATIONS ADVERSE EFFECT RESPONSIBILITIES/
BRANDNAME, PRECAUTION
CLASSIFICATION,
DOSAGE, FREQUENCY)
 Generic name: Aspirin  Analgesic and  Mild to moderate pain  People with allergy to  Acute aspirin toxicity –  Assess patient’s orientation
 Brand name: Aspergum, antirheumatic- inhibits salicylates or NSAIDs. respiratory alkalosis, to time and place as the
Bayer, Easprin, Ecotrin, prostaglandin (an  Fever This is more common to hemorrhage, tachypnea, drug may cause dizziness
Empirin, Genprin, inflammatory mediator) people with nasal confusion, asterixis, and confusion.
Halfprin, Norwich synthesis  Inflammatory polyps, asthma, and pulmonary edema,  Give drug with food or after
 Pregnancy Category: D conditions such as chronic urticaria. seizures, tetany, metabolic meal if GI upset occurs.
 Drug Classes: Analgesic,  Antipyretic effect – this rheumatic fever,  People with hemophilia, acidosis, renal and  Assess skin color and
Anti-inflammatory, action is not fully arthritis, and allergy to tartrazine respiratory failure presence of lesions as this
Antiplatelet, Antipyretic, understood but drug study spondyloarthropathies (cross-sensitivity is  Aspirin intolerance – may indicate hepatotoxicity,
Antirheumatic, NSAID, of aspirin is correlated with common), bleeding exacerbation of allergy, bleeding, and other
Salicylate the ability of the drug to  Reduction of risk of ulcers, blood coagulation bronchospasm, rhinitis complications.
act in the recurrent transient defects, and with  Gastrointestinal: nausea,  Observe patient for signs
thermoregulatory center ischemic attack Vitamin K deficiency dyspepsia, heartburn, and symptoms of bleeding
of the hypothalamus by (precursor to stroke) (increased risk of epigastric discomfort, such as easy bruising,
blocking the endogenous or cardiovascular bleeding) anorexia, hepatotoxicity bleeding in the gums, and
pyrogen through inhibiting accident (stroke) in  Caution with people who  Hematologic: occult blood nosebleeds.
synthesis of prostaglandin patients with history have impaired renal loss, hemostatic defects  Monitor vital signs.
intermediary. of TIA due to fibrin function, children and  Hypersensitivity:  Instruct to avoid OTC drugs
platelet emboli or teenagers (risk for anaphylactoid reactions to as many of those contain
 Antiplatelet – aspirin drug ischemic stroke developing Reye’s anaphylactic shock aspirin so serious overdose
study reveals the ability of Syndrome), patients who  Salicylism: dizziness, can occur.
the drug to inhibit  Unlabeled use: will have surgery within tinnitus, difficulty hearing,  Encourage client to increase
thromboxame A2 (a potent prophylaxis against 1 week, and pregnant nausea, vomiting, oral fluid intake to facilitate
vasoconstrictor and cataract formation women (it readily diarrhea, mental excretion of drug.
inducer of platelet with long-term use crosses placenta and is a confusion
aggregation) synthesis possible teratogen) as
well as lactating
mothers.

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