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    Physioex Lab Report: Pre-Lab Quiz Results

    Uploaded by

    Anggina Siregar
    1) The document describes an experiment examining chemical synaptic transmission and neurotransmitter release. It provides the results of a student's PhysioEx lab report, including pre-lab and post-lab quiz scores and answers. 2) The experiment tested how varying calcium ion and magnesium ion concentrations in the extracellular solution affected neurotransmitter release from axon terminals. 3) The results showed that removing calcium prevented release, low calcium allowed small release, and magnesium reduced release compared to the control solution by blocking calcium channels.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Physioex Lab Report: Pre-Lab Quiz Results

    Uploaded by

    Anggina Siregar
    235 views3 pages
    1) The document describes an experiment examining chemical synaptic transmission and neurotransmitter release. It provides the results of a student's PhysioEx lab report, including pre-lab and post-lab quiz scores and answers. 2) The experiment tested how varying calcium ion and magnesium ion concentrations in the extracellular solution affected neurotransmitter release from axon terminals. 3) The results showed that removing calcium prevented release, low calcium allowed small release, and magnesium reduced release compared to the control solution by blocking calcium channels.

    Original Description:

    Original Title

    PhysioEx Exercise 3 Activity 8

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    1) The document describes an experiment examining chemical synaptic transmission and neurotransmitter release. It provides the results of a student's PhysioEx lab report, including pre-lab and post-lab quiz scores and answers. 2) The experiment tested how varying calcium ion and magnesium ion concentrations in the extracellular solution affected neurotransmitter release from axon terminals. 3) The results showed that removing calcium prevented release, low calcium allowed small release, and magnesium reduced release compared to the control solution by blocking calcium channels.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    235 views3 pages

    Physioex Lab Report: Pre-Lab Quiz Results

    Uploaded by

    Anggina Siregar
    1) The document describes an experiment examining chemical synaptic transmission and neurotransmitter release. It provides the results of a student's PhysioEx lab report, including pre-lab and post-lab quiz scores and answers. 2) The experiment tested how varying calcium ion and magnesium ion concentrations in the extracellular solution affected neurotransmitter release from axon terminals. 3) The results showed that removing calcium prevented release, low calcium allowed small release, and magnesium reduced release compared to the control solution by blocking calcium channels.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
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    Neurotransmitter release at synapses is triggered by an influx of calcium ions into the axon terminal during an action potential. Neurotransmitters are stored in synaptic vesicles and released via exocytosis into the synaptic cleft.

    Neurotransmitter is stored in synaptic vesicles in the axon terminal and released via calcium-dependent exocytosis when an action potential reaches the terminal. The amount of neurotransmitter release is proportional to the stimulus intensity.

    The amount of neurotransmitter release is affected by the stimulus intensity and the extracellular concentrations of calcium and magnesium ions.

    11/30/2020 PhysioEx Exercise 3 Activity 8

    PhysioEx Lab Report


    Exercise 3: Neurophysiology of Nerve Impulses
    Activity 8: Chemical Synaptic Transmission and Neurotransmitter Release
    Name: Anggina Maulida Siregar
    Date: 30 November 2020
    Session ID: session-4b71caee-a4af-88f0-b029-6329d4d2b68b

    Pre-lab Quiz Results


    You scored 100% by answering 5 out of 5 questions correctly.

    1 The end of the axon where it contacts a target is called the

    You correctly answered: axon terminal.

    2 Neurotransmitter is released into the synaptic gap by

    You correctly answered: exocytosis.

    3 Exocytosis of neurotransmitter from the axon terminal is triggered by an increase in the


    intracellular concentration of

    You correctly answered: Ca2+.

    4 Neurotransmitter released into the synaptic gap reaches the target cell by

    You correctly answered: diffusion.

    5 At the target, neurotransmitter

    You correctly answered: does all of the above.

    Experiment Results
    Predict Questions
    1 Predict Question 1: You have just observed that each action potential in a burst can trigger
    additional neurotransmitter release. If calcium ions are removed from the extracellular
    solution, what will happen to neurotransmitter release at the axon terminal?

    Your answer: There will be more neurotransmitter release.

    2 Predict Question 2: What will happen to neurotransmitter release when low amounts of
    calcium are added back to the extracellular solution?

    Your answer: Neurotransmitter release will increase a small amount. i


    https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex3/act8/ 1/3
    11/30/2020 PhysioEx Exercise 3 Activity 8

    3 Predict Question 3: What will happen to neurotransmitter release when magnesium is


    added to the extracellular solution?

    Your answer: There will be less neurotransmitter release than in the control solution.

    Stop & Think Questions


    1 Why does the stimulus intensity affect the amount of neurotransmitter release at the axon
    terminal?

    You correctly answered: Both "The stimulus intensity directly affects the amount of calcium
    entering the axon terminal." and "The stimulus intensity proportionally affects the number
    of synaptic vesicles that discharge their contents into the synaptic cleft." are correct.

    2 Why is there no neurotransmitter release from the axon terminal when there are no calcium
    ions in the extracellular solution?

    You correctly answered: Exocytosis of the synaptic vesicles is calcium dependent.

    3 Why did the high intensity stimulation fail to trigger the same amount of neurotransmitter
    release in the presence of extracellular Mg2+ as in the control extracellular solution?

    You correctly answered: Mg2+ blocks the calcium channels in the axon terminal.

    Post-lab Quiz Results


    You scored 100% by answering 4 out of 4 questions correctly.

    1 How is the neurotransmitter stored in the axon terminal before it is released?

    You correctly answered: contained in synaptic vessicles.

    2 Are neurotransmitter molecules released one at a time or in packets?

    You correctly answered: in packets.

    3 With the normal extracellular calcium concentration, [Ca2+], when the action potential
    reaches the axon terminal it triggers

    You correctly answered: release of neurotransmitter by exocytosis.

    4 Comparing the low intensity stimulus to the high intensity stimulus, the high intensity
    stimulus causes

    You correctly answered: more synaptic vesicles to undergo exocytosis.

    Review Sheet Results


    i
    https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex3/act8/ 2/3
    11/30/2020 PhysioEx Exercise 3 Activity 8

    1 When the stimulus intensity is increased, what changes: the number of synaptic vesicles
    released or the amount of neurotransmitter per vesicle?

    Your answer:

    jumlah dari vesikel sinaptik.

    2 What happened to the amount of neurotransmitter release when you switched from the
    control extracellular fluid to the extracellular fluid with no Ca2+? How well did the results
    compare with your prediction?

    Your answer:

    disana tidak akan ada neurontransmitter karena eksositosis adanya neurontransimitter


    berasal dari akson terminal yang dipancing oleh peningkatan dari ion calsium.

    3 What happened to the amount of neurotransmitter release when you switched from the
    extracellular fluid with no Ca2+ to the extracellular fluid with low Ca2+? How well did the
    results compare with your prediction?

    Your answer:

    Neurontransmitter akan berkurang sesuai prediksi karena ion kalsium memberikan


    konsentrasi yang rendah.

    4 How did neurotransmitter release in the Mg2+ extracellular fluid compare to that in the
    control extracellular fluid? How well did the result compare with your prediction?

    Your answer:

    pada neurontransmitter yang dilepaskan akan lebih sedikit ketika magnesium ditambah.

    5 How does Mg2+ block the effect of extracellular calcium on neurotransmitter release?

    Your answer:

    ketika ion magnesium ditambahkan pada cairan ekstraseluler nya diblokir oleh calsium
    channel yang mana akan menghambat pelepasan neurontransmitter.

    i
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