A Systematic Review On The Prevalence of Postpartum Depression and The Associated Risk Factors in Asia
A Systematic Review On The Prevalence of Postpartum Depression and The Associated Risk Factors in Asia
A Systematic Review On The Prevalence of Postpartum Depression and The Associated Risk Factors in Asia
ISSN No:-2456-2165
Dr. C. N. Ram Gopal Professor, Counselling Psychology, Chettinad Academy of Research and Education,
Kelambakkam, Chengalpattu Dist., Chennai - 603103, India.
Our current understanding of the epidemiology of Fifty-eight studies about postpartum depression were
postpartum depression is largely based on a few regional selected that were conducted across various Asian countries.
studies. The main objective of this current review is to fill The studies are grouped under studies performed in India, in
this gap, by providing an updated estimate of the burden of the Arabic Region and other Asian countries like Pakistan,
postpartum depression in across the Asian continent to Japan, China etc. It is to be noted that 31 studies from
synthesize the important risk factors and to provide India,11 studies from the Arabic region and 16 studies from
evidence-based data for prioritizing maternal mental health other Asian countries were reviewed for this study. The
and wellbeing. This review aims to assess the prevalence of special feature of this study is that studies conducted across
PPD in Asia and to ascertain risk factors for PPD in these a time span of 20 years (2000-2020) have been chosen for
settings. Although systematic reviews were published based this systematic review .Of the 58 studies, the majority of 32
on studies from India, Arabic Region and other Asian studies have been conducted in the very recent time period
countries individually for different time lines, there is no 2015-2020.It is significant to note that a maximum of 22
comprehensive review of postpartum depression prevalence studies in the recent time period 2015-2020 were conducted
and associated risk factors across the Asian continent for a in various states of India like Maharashtra, Madhya Pradesh,
vast time period of 2000-2020. Delhi, Gujarat and Karnataka.16 studies are chosen which
fall under the time period 2010-2015.8 studies have been
III. METHODOLOGY conducted during 2000-2009.Moreover 55 out of 58 studies
analysed the risk factors associated with PPD. Please refer to
The literature search was done using electronic Table 1 indicating the number of studies contributed from
database like PubMed, Elsevier, PlusOne, Research Gate three geographical regions India, Arabic Region and other
and Google Scholar. Search terms like postnatal depression, Asian countries.
Table 1: Geographic distribution and number of studies across India, Arabic Region & other Asian
Countries during 2000-2020
India Arabic Region Other Asian Countries
Place of Study No. of studies Place of Study No. of studies Place of Study No. of studies
Tamil Nadu 3 Riyadh 1 Srilanka 1
Pondicherry 1 Saudi Arabia 1 Pakistan 2
Kerala 2 Sudan 1 Philippines 1
Pondicherry 1 Jordan 1 China 2
Andhra Pradesh 3 Bahrain 1 Iran 3
Karnataka 5 Cyprus 1 Indonesia 1
Gujarat 4 Lebanon 1 Turkey 1
Goa 1 Laos 1 Maldives 1
Madhya Pradesh 2 Syria 1 Vietnam 1
Maharashtra 2 UAE 1 Oman 1
Delhi 2 Kuwait 1 Thailand 1
Nepal 3
Assam 1
Rajasthan 1
Jharkhand & Orissa 1
Scale of Measurement
Out of 58 studies,46 studies used Edinburg Postpartum
Depression Scale (EPDS) to screen postpartum Depression.
However, different cut off scores were used in different
studies). A systematic review by Gibson et al. stated that
cut-off points at 9 ⁄ 10 and 12 ⁄ 13 for PPD were widely
accepted cut-off points to indicate possible and probable
depression respectively.(7)The sensitivity of the English
Version of EPDS was 86% and the specificity was
Time & Place of Recruitment 78%.However, different cut off scores were used in different
All the 58 studies recruited mothers in their postnatal studies. In 15 studies, the cut-off score was calculated at
period. Please refer Table 1 showing the Geographic ≥13.In 4 studies the cut off score used was >13.4 studies
distribution and number of studies across India, Arabic used a cut-off score ≥12.7 studies used a cut-off score >12.6
Region & other Asian Countries during 2000-2020.The studies used a cut-off score ≥10.1 study used a cut-off score
initial screening was done in a range of 1-8 weeks. Some 10 ,1 study used 10,5 and another study used a cut-off score
studies followed up participants until 12 months postpartum. 9.In a study conducted in Jordan, the EPDS score were
Twenty-two studies from various states in India recruited classified as mild, moderate and severely depressed. The
mothers from Hospitals for the studies.11 studies from mild score range was calculated at 10-15, the moderate score
Arabic Region and 11 studies from other Asian countries range was calculated at 16-20 and the severe score range
recruited mothers from Hospitals. It is also significant to was calculated >21.In India, the English Version of EPDS
note that 4 studies in China (8 centres) ,Saudi Arabia(5 was translated to the regional languages like Tamil,
centres), Sudan(2 centres) and Jordan(4 centres) performed Kannada, Guajarati and Assamese. In the other Asian
multi centre hospital studies.12 studies were exclusively countries like Thailand, the Thai version of EPDS scale was
community based studies wherein 6 studies were conducted used. Arabic and Persian version of the scale was used in
in India and 6 in other Asian countries.2 studies conducted Arabic region. In a study conducted in Vietnam and Turkey,
in Madhya Pradesh and Nepal recruited mothers from a the Vietnamese and Turkish version of the scale was used
combination of hospital and community. accordingly. Please refer Table 2 showing the summary of
the studies with prevalence and tools used
Study Design
Forty-two studies adopted a cross sectional research Apart from EPDS being used to screen postpartum
design to estimate the prevalence of PPD. Longitudinal depression, other tools were also used in some studies. In a
panel approach was adopted only by 9 studies wherein the study conducted in Andhra Pradesh, the Hamilton Rating
mothers were screened for PPD multiple times in different scale for Depression. The screening categories were 0-8 :
time intervals to assess the level of depression. The other Low probability depression 8-12 : Baby blues 13-14 :
research designs used across the remaining studies used a Possibility of depression 15+ : Highly probability of
case control study to determine the risk factors, Quasi depression. In a study conducted in Gujarat, Predictive
Experimental Study, observation study, randomised control Index for PPD was used to screen depression. The Kessler-
trial. 10 item scale was used to screen depression in Jharkhand
and Orissa. A combination of Brief Psychiatric Rating Scale
Sampling Size & Sampling Method (BPRS), Hamilton Anxiety Rating Scale (HARS), and
8 studies used the Probability Sampling Method Hamilton Rating Scale for Depression (HDRS) was used to
wherein simple random Sampling was used in 3 studies screen depression in a study conducted in Delhi. In a study
(Madhya Pradesh, Bahrain and Iran. Cluster sampling was conducted in Pakistan, Aga Khan University Anxiety and
used in a study conducted in Karnataka and Indonesia. Depression Scale (AKUADS) was used. A study conducted
Systematic Random Sampling was used in Assam. In a in Zabol (Iran) used Beck Depression Inventory to screen
Study conducted in Thailand, Stratified Multistage sampling the level of PPD.
was used for Stage 1 and Simple Random Sampling was
used in Stage 2.17 Studies used the Non-probability V. PREVALENCE OF POSTPARTUM
Sampling techniques. It was used in 1 study conducted in DEPRESSION
Tamil Nadu,1 conducted in Andhra Pradesh and 2
conducted in Gujarat. Convenient Sampling was used in The prevalence of postpartum depression varied
studies conducted in Maharashtra, Pakistan, Jordan, Kuwait, widely due to the different cut off points and varying
Riyadh and Syria. Consecutive sampling was used in studies timelines used in different studies. Please refer Table 2
conducted in Karnataka, China and Vietnam. In many showing the summary of the studies with prevalence and
studies the small sample size became a major limitation to tools used.2 Studies in India (Gujarat and Karnataka)
Table 2. showing the summary of the studies with prevalence and tools used
Author and Research Cut off Data collection No of No of mothers with
Setting Tools
Place of Study Design score period women PPD
India
2-3 days
Latha et al(2017) EPDS(Ta postpartum,6-8
Hospital Case control >12 256 23%
Tamil Nadu mil) weeks
postpartum
Shriraam, et
Cross 6 weeks
al(2019) Hospital EPDS ≥10 365 11%
sectional postpartum
Tamil Nadu
Chandran et randomised last trimester,
CIS-
al(2002) Community placebo NA 6-12 weeks 359 11%
R(Tamil)
Tamil Nadu control trial postpartum
Poomalar GK et
Cross
al(2014) Hospital EPDS ≥13 NA 254 26(10.2%)
sectional
Pondicherry
Santhosh
Kuriakose et Cross 2-4 weeks upto
Hospital EPDS ≥11 250 27.60%
al(2020) sectional 1 year
Kerala
Heera Shenoy et
Cross
al(2019) Hospital EPDS >13 2-6 weeks 119 35(29.4%)
sectional
Kerala
30(30% - mild
Ch. Beaula Rani
Cross depression & 18%
et al(2019) Community EPDS NA NA 100
sectional moderate
Andhra Pradesh
depression)
11(18.33%) of them
had low probability
of depression,
33(55%) of them had
P. Latha et baby blues,
Cross
al(2016) Hospital EPDS NA 0-6 weeks 60 11(18.33%) of them
sectional
Andhra Pradesh had high probability
of depression,
5(8.33) of them had
possibility of
depression
0-8 : Low
probabilit
y
depression
8-12 :
Baby
Hamilton
Lakshmi blues 13-
prospective Rating
Bhuvana G et 14 : 1 week
Hospital observationa scale for 236 74(31.4%)
al(2016)Andhra Possibility postpartum
l study Depressi
Pradesh of
on
depression
15+ :
Highly
probabilit
y of
depression
Siddharudha
Shivalli et Cross
Hospital EPDS ≥13 4-10 weeks 118 31.40%
al(2015) sectional
Karnataka
Avita Rose
Johnson et Cross
Hospital EPDS ≥13 6-8 weeks 123 46.90%
al(2015) sectional
Karnataka
Anamika
Agarwala et Cross
Hospital EPDS ≥10 6 months 410 21.50%
al(2019) sectional
Karnataka
Ganraj Bhat
Sankapithilu et Cross 0-3 months 20%(10)-C-
Hospital EPDS >12 100
al(2010) sectional postpartum SEC,16%(8)-Normal
Karnataka
Suguna A et
Cross
al(2015) Hospital EPDS >9 NA 180 18%
sectional
Karnataka
Desai Nimisha D
Cross upto 1 year
et al(2012) Hospital EPDS NA 200 12.50%
sectional postpartum
Gujarat
Himadri L. Patel
Cross
et al(2015) Hospital EPDS >10.5 NA 134 48.50%
sectional
Gujarat
(22-30)-
10/4%
Vidhi Prakash (12-21)-
Cross
Modi et al(2018) Hospital EPDS 16.4% 1-6 weeks 250 20.40%
sectional
Gujarat <12-
199(79.6
%)
Dr. Darshana
Cross
Hirani(2015) Community EPDS ≥10 1-6 weeks 516 12.00%
sectional
Gujarat
Vikram Patel et 6-8 weeks and 6
al(2002) Hospital NA EPDS NA months 270 59(23%)
Goa postpartum
224-
Sujit D. Commun
Community Cross 8.8% - community &
Rathod(2018) EPDS NA ity
& Facility sectional 18.5% - facility
Madhya Pradesh &130-
Facility
Gita Guin et prospective
al(2018)Madhya Hospital observationa EPDS ≥13 NA 500 64(12.8%)
Pradesh l study
Mean Scores - s
Dhwani.Prakash.
6 weeks 1.58, 10.58 and
Sidhpura et Observation MKS
Hospital ≥10 primparous 300 14.80 of upper,
al(2018) al Study &EPDS
women middle and lower
Maharashtra
SES women
Nikhil
Cross 1-6 weeks
Dhande(2018) Community EPDS NA 67 24%
sectional postpartum
Maharashtra
Saurav Basu et
Cross less than 1 year
al(2019) Hospital EPDS ≥10 210 61(29%)
sectional infant
Delhi
Adya Shanker
BPRS,H 1st day to 4
Srivastava et longitudinal 12% depression,4%
Hospital ARS,HD NA weeks 100
al(2015) study anxiety
RS postpartum
Delhi
Kamal Narayan
Cross
Kalita et al(2010) Hospital EPDS >13 6 weeks 100
sectional
Assam
prospecti
18.37%, 15.19%,
Irma Nurbaeti et ve 1,2 and 3
and 26.15% at one,
al(2018) Hospital longitudi EPDS ≥13 months 283
two and three
Indonesia nal study postpartum
months
design
Ayse Figen
Turkcapar et Cross
Hospital EPDS ≥13 6-8 weeks 671 15.40%
al(2015) sectional
Turkey
R. Abdul
Prospecti 36 weeks ,1 and
Raheem et 27% at 1 month and
Hospital ve cohort EPDS ≥13 3 months 458
al(2018) 12% at 3 months
study postpartum
Maldives
J.R.W. Fisher et
Cross 6 weeks
al(2004) Hospital EPDS >12 506 166(33%)
sectional postpartum
Vietnam
Irandokht Asadi
Beck
Sadeghi Azar et Cross
Hospital Depression ≥17 2-8 weeks 408 40.40%
al(2012) sectional
Inventory
Zabol,Iran)
Pegah Taherifard
Cross
et al(2013) Hospital EPDS ≥13 197
sectional
Ilam,Iran
Cross 8 weeks
Hospital EPDS >13 1200 36.30%
Maryam Rouhi et sectional postpartum
al(2012)Azerbaij
an,Iran
VI. RISK FACTORS ASSOCIATED WITH aspects that form a part of the SES are mentioned Financial
POSTPARTUM DEPRESSION Dependence ,Low income, low family income, low asset
ownership, annual household income, economic deprivation
The risk factors associated with PPD were classified and poverty. The second major risk factor associated with
under five different categories. They are 1.Socio- PPD is the Age reported in 19 studies.2 studies conducted in
demographic variables,2.Pregnancy and Birth Related Iran (Zabol and Azerbaijan) revealed that the younger
Variables,3.Infant Variables,4.Family Relationships and marital age is associated with PPD. In a study conducted in
Psychosocial factors.Please refere Table 3 showing the UAE , higher marital age is associated with PPD.2 studies
factors identified to be associated with Postpartum conducted in India(Kerala and Delhi),India observed that
Depression. getting married at young age is a risk factor associated with
PPD. To the contrary, a study conducted in Jharkhand &
1.Socio-demographic Variables Orissa revealed that higher maternal age was associated with
The most prominent variable associated with PPD Low PPD. Level of Education was a risk factor in 6 studies. In a
Income or Socio-Economic Status (SES). It has been study conducted in Karnataka ,India it is observed that
reported that 22 studies indicate that the low income or SES higher level of education has been associated with PPD. In 1
contributes majorly as a risk factor to PPD. The various study conducted in Tamil Nadu, illiteracy was a contributing