The Endocrine System
The Endocrine System
The Endocrine System
Hormones are chemical messengers that are secreted by ductless glands or endocrine glands sent
to act on a specific organ in the body to control or regulate different processes. They are
transported by the circulatory system to their ‘target’ organ to trigger the required activity.
Hormones in complex organisms (including humans) control a variety of functions like
metabolism, growth, sexual development, respiration and different aspects of behaviour.
Characteristics of Hormones:
Hormones are secreted directly into the bloodstream. They are carried to all parts of the
body, but their action is only on specific parts of the body, called the target organ. Each
hormone is associated with a different target organ.
They are excreted by the body as they cannot be stored.
Hormones do not take part in the reaction themselves; they only stimulate cells and
biochemical pathways to function.
Chemically, hormones are made of proteins.
Along with the nervous system, endocrine glands are responsible for control and
coordination of bodily activities.
Hyposecretion: This refers to the condition where the hormone is secreted in lower than normal
quantities. Different hormones cause different deficiencies due to hyposecretion.
Hypersecretion: This refers to the condition where the hormone is secreted in excess. Different
hormones cause different conditions when secreted in excess.
Some glands, for example, the pancreas can be both endocrine and exocrine in nature.
Testes and ovaries have dual functions i.e., they produce hormones as well as gametes
needed for reproduction.
The pituitary gland is called the master gland because it produces secretions to control the
actions of other glands.
Feedback mechanism: A feedback mechanism is a process that uses the conditions of one
component to regulate the function of another.
Hormones are normally controlled by a feedback mechanism. The feedback mechanism is
necessary to maintain homeostasis.
Positive and negative feedback mechanism:
A positive feedback loop causes a self-amplifying cycle where a physiological change leads to
an even greater change in the same direction.
Uterine contractions during childbirth is an example of positive feedback. The uterus is
instructed to continue to contract till delivery is completed.
A negative feedback loop is a process in which the body senses a change and activates
mechanisms to reverse that change.
Regulation of blood sugar level is an example of negative feedback mechanism.