(I) Simple Proteins

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Protein are of three types-

(i) Simple (ii) Conjugated (iii) Derived

(i) Simple Proteins :


They are made up of only amino acids.
They are of two types – Fibrous and globular proteins.
1. Fibrous proteins :
They are thread like structural proteins.
Fibrous protein generally contain secondary structure and are insoluble in water e.g.,
collagen of connective tissue, actin and myosin of muscles, keratin of scales, feathers,
hairs, claws, nails, horns and hoofs, silk of spider web.
2. Globular proteins :
They are spherical non-contractile proteins which may be enzymatic or non-enzymatic.
They have tertiary or quaternary structure.
Smaller globular proteins are usually soluble in water and are not coagulated by heat e.g.,
histones.
Egg albumin, serum globulins and glutelins are examples of large globular proteins, which
get coagulated by heat.
(a) Albumins :
They are water soluble and occur as serum albumin in blood plasma and loctoalbumin in
milk.
(b) Globulins :
They are soluble in weak acids and alkaline solution but insoluble in water e.g.
lactoglobulin in milk.
(c) Histones :
They are water soluble and are rich in lysine and arginine (amino acids) they occur in
eukaryotic DNA.
(d) Protamines :
These water soluble arginine rich proteins occur in DNA of spermatozoa of some fishes
e.g. salmine in Salmon.
(e) Gluteins :
They occur only in plants like wheat e.g., glutenin.
Protein are of three types-
(i) Simple (ii) Conjugated (iii) Derived

(f) Prolamines :
They occur only in plants e.g., zein in corn and gliadin in wheat.
(ii) Conjugated proteins :
These are formed by the binding of a simple protein with a non-protein called the
prosthetic group.
These are of following types-
(a) Chromoproteins :
These contain pigment (coloured) as prosthetic group e.g., haemoglobin,
haemocyanin, cytochrome, flavoprotien and rhodopsin.
(b) Glycoproteins :
Contain protein + carbohydrate less than 4% eg., plasma glycoprotein secreted
from liver and immunoglobulin produced by lymphocyetes.
(c) Mucoprotein :They have carbohydrate more than 4% e.g., Muerins of bacteria cell
wall ossomucoid in bones, tendenomucoid in tendons, chondromucoid in cartilage.
Various mucoproteins are found in vitrous humor synovial fluid.
(d) Nucleoproteins :
Contain protein + nucleic acid. e.g., histone and non-histone protein join with DNA
to make chromosomes.
(e) Metalloproteins :
Contain protein + metal ions e.g., Arginase (Mn & Mg), Carbonic anhydrase (Zn),
Tyrosinase (Cu), Xanthine oxidase (Mo) etc.
(f) Phosphoproteins :
Contain protein + phosphate e.g., casein in milk and ovo-vitellin in eggs.
(g) Lipoproteins :
Contain protein + lipids e.g., high density lipoprotein (HDL), low density lipoprotein
(LDL) and very low density lipoprotein (VLDL). Mostly important in membranes.
(iii) Derived proteins : These are denatured or hydrolysed protein.
Primary derived protein : Denatured product e.g. Fibrin, Myosan
Protein are of three types-
(i) Simple (ii) Conjugated (iii) Derived

Secondary derived protein : Digestion product of proteins eg. Peptones, Proteose di &
tripeptide.
Protein are of three types-
(i) Simple (ii) Conjugated (iii) Derived

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