11-Interactions Cellulaires Amina - TBR

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Tetbirt Amina.

Anfekachion + cperahon ente té RT (wtact dred) Cy olkinej


i mrteuls d'hdhen'an (ex:LFAA/ICAMA) t fackur sslitdes chimaokenes
RI»OLs (2d) nature d'Agkpe ce reonse
9 a ( R I ¢a« )/Aq erta4 Tdep (Rr hurnoral +T/
AA exka Tmdepercaut (RI umoal sansLT)
RI aispecfqse LTH-CHH I cLTs- CHHI
CPA degrade Ag em pephide Plesent CMH-pephde anl1

stiuulatnice-
OCPA pmle Stionnelks Pacthi v:k Co-

dendrikigue + 4 elocace pour u her RILTar = t+ CrMHL


lacephaje - ¢ phagoytne TFN, y s e (panasite tta f * )
exptme HLA L^CPA
d
B = excellete ¢PA Reponsg 2 ( BCR = Rec ++ speatqe g)
O Achvahos des CPA
GMCSF, IFNI , TNF CPA 1epfessiou d'HLAI
Rec du Fe des TG
LTheleeh m.o-shmalaho 67,B1, LFAL, TOATY
intera chbn CPA-LT (LTco4t -> che Jochestre oe
RI)llJo
Asanal TCR-CMHpephde (pas lfzad) + mleculed aohesria
LT-CPA LFA4-TcAMA/ CD.2- LFA3/TCAM3 DC sign
s g m a aison de Co28+CTL4 (LT) - B7+ B (eD%4CDE)A
expression nd LT4 protenge - 2 ptocuchon TLe ( potferahon LT)
.CDHOL- CoHo (¢PA)
.CD5 (chaineot de Rec T2,)» Ree TL2 anile
CMHI
CTLA (mdulahor RI)
prolfercahon.
L
Uffrenciabion t electne helpe r (aprs tromsopkon de gints
des ytoliues
LTh ILZ + IFNy = ePonse f
>LTh 2 IL4+ILS +ILG +ILA ponse mumnale(AC)
RIspecafque Cyhohoxrque: LTy (anti Virale /anh terale)
Coaperahion pai
T4 CPA
LTg LTh okines
T g - CPA (¢ dhe)» Pephidle auee CtiHT

Mecami me de yse ablep CTL


LTeogt fohos, CTL («9tetbry) CTL- é A FasL- Fas

haivon faamentaho n JAON nt ¢ apophoe


CTL bere, penfonine +4amnne ye ¢ (aue made)
RI humaale
R. hmral (A¢)~ Tdepencach ooperakon LTy-LS
LT etLB reannaisset es dekesminanwks Ag
LB (CPA)@LT LBBcR -Ag pephide + CMHI p e l k awLT
mterathon B-T bidvechonueL ( 2 smt eta ves )
B 2CO28
- »couO L(LT)- CD4O (LB) OLB
commutation Asotopque Switd
aylokine mod fcahon oes cla Sses des 1g

Lp Dflerenciahion B pBasinocye secre


Lgs

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