Acute Asthma Management

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Asthma - Management of acute

exacerbation in adults
Immediate treatment:

Start O2 if saturations < 92%, aim sats 94–98%


Short acting B2 agonists
Salbutamol 5mg (or terbutaline 10 mg) nebulized with O2

Hydrocortisone 100mg IV or prednisolone 40–50 mg PO

If life-threatening features present:

Give salbutamol nebulizers every 15 minutes, or 10 mg continuously

Add in ipratropium 0.5mg to nebulizers

Give single dose of magnesium sulfate (MgSO4) 1.2–2g IV over 20 minutes

If improving within 15–30 minutes:

Nebulized salbutamol every 4 hours

Prednisolone 40–50 mg PO OD for 5–7 days

Further reading:

Oxford Handbook of Respiratory Medicine 3rd Edition page 125 - 152

http://patient.info/doctor/bronchial-asthma

https://www.brit-thoracic.org.uk/document-library/clinical-information/asthma/btssign-asthma-

guideline-2016/

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