GBA-1000 Sevice Manual

SERVICE MANUAL
GBA-1000 Biochemistry Analyzer
Goldsite Diagnostics Inc.

All rights reserved.
 Please read this manual and perform instrument related operations
when an abnormality occurs in the instrument.
 Please take normal protective measures when handling instrument
failures and maintaining instrument functions.
 Untrained personnel must maintain and repair the instrument under
the guidance of qualified personnel.

Version: 00
Table of Contents
1. Chapter I System Installation .............................................................................................................. 1
1.1. Environmental requirements................................................................................................. 1
1.2. Power requirements ............................................................................................................. 1
1.3. Temperature and humidity requirements.............................................................................. 1
1.4. Water supply and drainage requirements ............................................................................ 2
1.5. Installation process ............................................................................................................... 2
2. Chapter II Analyser Overview ............................................................................................................. 4
2.1. Analyser test principle .......................................................................................................... 4
2.2. Analyser overview ................................................................................................................ 5
3. Chapter III Components and functions ............................................................................................... 7
3.1. Components ......................................................................................................................... 7
3.1.1. Reaction disk drive shaft assembly............................................................................... 7
3.1.2. Reaction plate ............................................................................................................... 8
3.1.3. Optical module .............................................................................................................. 9
3.1.4. Reagent disk cooling module ........................................................................................ 9
3.1.5. Probe outer washing module ...................................................................................... 10
3.1.6. Pump ........................................................................................................................... 10
3.1.7. Touch screen ................................................................................................................11
3.1.8. Front cover .................................................................................................................. 12
3.1.9. Sample tray holder ...................................................................................................... 12
3.1.10. YZ axis movement module.......................................................................................... 13
3.1.11. Driver protect shell ...................................................................................................... 13
3.1.12. Plunger pump module ................................................................................................. 14
3.2. Program content: ................................................................................................................ 15

3.2.1. Instrument power on self-test...................................................................................... 15
3.2.2. Mainboard Power Supply Voltage Test: ...................................................................... 16
3.2.3. Reaction disk position calibration................................................................................ 16
3.2.4. Sample probe-washing well position calibration ......................................................... 18
3.2.5. Sample probe-reaction cuvette position calibration .................................................... 18
3.2.6. Sample probe-reagent disk position calibration .......................................................... 20
3.2.7. Sample probe-standard cup position calibration......................................................... 21
3.2.8. Sample probe-Micro cup position calibration .............................................................. 22
3.2.9. Sample probe-BCT (Blood collection tube) position calibration. ................................ 23
3.2.10. Sample probe-Bubble remove position calibration. .................................................... 24
3.2.11. Light position adjustment ............................................................................................ 24
3.2.12. Stirring calibration ........................................................................................................ 27
3.2.13. Sample tube detection calibration ............................................................................... 28
3.2.14. Reagent disk cover detection ...................................................................................... 29
3.2.15. Sample probe anti-collision function detection ........................................................... 30
3.2.16. Reaction disk control button function detection .......................................................... 30
3.2.17. Inlet and outlet components detection ........................................................................ 31
3.2.18. Serial port detection .................................................................................................... 31
3.2.19. USB port detection ...................................................................................................... 31
3.2.20. Net port detection ........................................................................................................ 31
3.2.21. Check cooling fans 1 and 2 on both sides of refrigeration components. .................... 31
3.2.22. Halogen fan detection ................................................................................................. 32
3.2.23. Pump valve detection (inner pump, solenoid valve, outer pump, waste pump) ......... 32
3.2.24. Probe inner waterflow detection.................................................................................. 33
3.2.25. Printer detection .......................................................................................................... 33
3.2.26. Time test ...................................................................................................................... 33

3.2.27. S/N number input ........................................................................................................ 33
4. Chapter IV Replacement of common parts....................................................................................... 34
4.1. Disassembly and precautions ............................................................................................ 34
4.2. Instrument pipeline installation requirements ..................................................................... 35
4.3. Replace modules ................................................................................................................ 36
4.3.1. Replace the pump unit ................................................................................................ 36
4.3.2. Replace the Washing well unit. ................................................................................... 38
4.3.3. Replace the optical unit ............................................................................................... 40
4.3.4. Replace halogen lamp ................................................................................................ 45
4.3.5. Replace the reaction disk original sensor ................................................................... 50
4.3.6. Replace the plunger pump .......................................................................................... 53
4.3.7. Replace the Thermal Printer Control Board ................................................................ 57
4.3.8. Replace the printer head ............................................................................................. 61
4.3.9. Replace the indicator light control board .................................................................... 64
4.3.10. Replace the Sensor board .......................................................................................... 65
4.3.11. Replace the reaction disk ............................................................................................ 67
4.3.12. Hall Sensor Board replacement .................................................................................. 70
4.3.13. Reaction disk motor module replacement .................................................................. 74
4.3.14. Reagent disk refrigeration module replacement. ........................................................ 77
4.3.15. Stirring module replacement. ...................................................................................... 79
4.3.16. QR code scanner replacement. .................................................................................. 81
4.3.17. Sample probe replacement ......................................................................................... 83
4.3.18. Screen module replacement ....................................................................................... 86
5. Chapter V Troubleshooting ............................................................................................................... 97
5.1. Z-axis Reset Failure ........................................................................................................... 97
5.1.1. Maintenance process .................................................................................................. 97

5.1.2. Repair procedure......................................................................................................... 98
5.2. Y axis Reset Failure ......................................................................................................... 101
5.2.1. Maintenance process: ............................................................................................... 102
5.2.2. Repair procedure....................................................................................................... 102
5.3. X axis Reset Failure ......................................................................................................... 104
5.3.1. Maintenance process ................................................................................................ 104
5.4. Plunger pump Reset Failure............................................................................................. 106
5.5. Reaction disk Reset Failure ............................................................................................. 108
5.6. Cooling system Failure ......................................................................................................110
5.6.1. Maintenance process .................................................................................................110
5.6.2. Repair procedure........................................................................................................110
5.7. Reaction disk heating Failure ............................................................................................112
5.8. Waste overflow ..................................................................................................................116
5.9. Rotary pump with no water supply ....................................................................................118
5.10. Sample tray holder overflow ............................................................................................. 120

5.11. Sample probe not stirring ................................................................................................. 121
5.12. Unable to power on normally............................................................................................ 126
5.13. Sample probe crash ......................................................................................................... 129
5.14. Liquid level detection abnormality .................................................................................... 134
5.15. Reaction disk not responses when press the disk control button .................................... 138
5.16. No liquid dispensing from the sample probe .................................................................... 140
5.17. Touch screen abnormality ................................................................................................ 144
5.18. USB Flash Drive unrecognized ........................................................................................ 147
5.19. Unable to connect to LIS .................................................................................................. 149

5.20. Printer abnormality ........................................................................................................... 153
5.21. Communication Timeout ................................................................................................... 156
5.22. Indicating light failure ........................................................................................................ 157
5.23. Insufficient clean water ..................................................................................................... 160
5.23.1. Repair process .......................................................................................................... 160
5.24. Waste water is full............................................................................................................. 161
5.25. Self-test abnormal ............................................................................................................ 162
6. Error code and explanation ............................................................................................................. 164

Chapter I System Installation
1. Chapter I System Installation

1.1. Environmental requirements
1) For indoor use only, environment without corrosive or flammable gas is required, as well as minimal
dust and good ventilation.
2) The size of the working bench where the analyzer is set should not be no smaller than 1 X 0.7m and
the height should not be lower than the height of the waste tank. The bench top should be flat
(inclination less than 1/200) without vibration and can withstand at least about 50 kg.
3) Avoid placing the analyzer in direct sunlight and any air flow or heat source.
4) Do not place the analyzer close to any high frequency equipment, such as centrifuges or high power
appliances with electromagnetic emissions, etc.
5) Place the analyzer in a spacious location for convenient power disconnection.
6) The analyzer should be placed at an altitude of maximum 2000m.
7) There should be switchboard and plumbing system near the analyzer.

Note: The working environment should be well ventilated to ensure heat dissipation, and
ventilation equipment should be used when necessary. However, direct airflow should be
avoided to the instrument, otherwise the reliability of the results may be affected.
1.2. Power requirements

1) Input voltage: AC. 220V±22V, Frequency: 50±1HZ.
2) Three-core power cord, grounding well; the fuse type is: F5L250V.
3) The instrument requires a well-grounded electrical outlet to provide the required power.
4) In order to ensure that the instrument can continuously complete the tests when the power is
suddenly turned off, the use of UPS system with power not less than 1500w is recommended.
5) The distance between the socket and the instrument should be less than 1 meter.
6) Neutral-to ground voltage must be set.
1.3. Temperature and humidity requirements
1) Working environment temperature: 10℃ - 30℃;
2) Relative humidity: 30% - 70%, non-condensing.

Attention: (i) The instrument must be operated within the specified ambient humidity and temperature
range, otherwise the results may be unreliable;
(ii) If the ambient temperature and humidity are out of the specified range, use an air
conditioning unit to adjust.
1
1.4. Water supply and drainage requirements

1) The water quality of the water supply must meet the requirements of CAP secondary level; the pure
water used is 100L, and the electrical conductivity is below 1 μs/cm.
2) Water consumption requirement: The water consumption per hour of the instrument is about 2-3 L,
please ensure sufficient water volume.
3) The water temperature of the water supply is 5 - 40°C.
4) The length of the waste liquid drain pipe shall not exceed 150cm, and the waste liquid tank shall not
be higher than the instrument.
1.5. Installation process

1) Confirm that suitable installation sites is available in the hospital: sufficient space; electrical
environment meets the requirements; room temperature and humidity meet the requirements.
2) Confirming reagents, calibrators, and quality control for installation.
3) Remove eight packing tapes inside and outside with scissors; unpack the box and check each
accessory according to the packing list and ask the hospital for acceptance.
4) Remove the protect pads and cut off the PE bag; check the integrity of the instrument.
5) Hold the four corners of the bottom of the instrument and carry the instrument to the designated
workbench.
6) Remove the high temperature tape from the reagent tray cover and take the tray cover out.
7) Cut the tie fastening the three-dimensional arm with scissors, and then slide the three-dimensional
arm forward and backward, left and right, up and down to confirm that the movement of each
component is smooth.
8) (Note: 1. Avoid damaging the wires and pipes when cutting the ties; 2. Make sure that slide the arm
back and forth, left and right only when the Z-axis slider is moved to the top to avoid bumping the
Probe.)
9) Use a knife to gently open the sealing tape on the accessory box to open.
10) Unpack and check each accessory according to the packing list, then ask the hospital for
acceptance.
11) Fill the Cleaning tank with an appropriate amount of distilled water, then put the inlet conduit into the
tank and tighten the lid.
2
12) Fix the two hoses to the inlet conduit on the back of the instrument according to the type of
connectors and tighten clockwise.
13) Open the lid on the waste container, then put the drain conduit into the tank and finally tighten the
lid.
14) Press the tab of the drain connector on the back of the instrument, then insert the drain tube into the
connector to the end and release the tab.
15) Connect the instrument to the power, then turn the power switch to the “-” side to turn on the power.
16) Click the On/Off switch in the lower right corner of the instrument to turn it on and wait for the
instrument to initialize.
17) Enter the corresponding account ID and password to enter the main interface, and then perform
Perfusion and Exhaust operations for more than three times.
18) Wait 30 minutes for the light source to stabilize.
19) Perform normal calibration, quality control, and sample test according to the Operation manual.
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Chapter II Analyser Overview
2. Chapter II Analyser Overview

2.1. Analyser test principle
The basic principle of the analyzer is spectrophotometry, i.e. the Lambert-Beer law, which is the
theoretical basis for the quantitative method of absorption spectroscopy.
The mathematical expression is:
A=Kbc
Where A is the absorbance; K is the molar attenuation coefficient or absorptivity of the attenuating
species; b is the optical path length; c is the concentration of the attenuating species. When the
concentration Unit is mol/L, and the unit of K is L/mol•cm, the molar absorption coefficient is usually
represented with ε. The molar absorption coefficient represents the absorption characteristic of a
substance for radiation of a certain wavelength.
For a particular substance, when absorbing radiation of different wavelengths, the corresponding
molar absorption coefficient is also different, that is, ε=fλ. If the concentration of the immobilized
substance and the thickness of the liquid layer are plotted as the absorbance A to the wavelength λ of
the radiation, the absorption spectrum of the substance is obtained. The absorption spectrum curve
embodies the properties of the material, and the different materials have different characteristic curves.
Using the standard curve method, a certain maximum absorption wavelength is selected from the
absorption spectrum of the substance to be tested, and their absorbance are respectively measured at a
range of a standard solution of different concentrations, and the absorbance is plotted against the
concentration. If the absorption of light by the substance to be tested conforms to Lambert-Beer's law, a
straight line passing through the origin, i.e. the standard curve, should be obtained. The absorbance of
the sample solution was measured under the same conditions, and the concentration of the sample
solution was read on a standard curve.
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2.2. Analyser overview

Front view
Touch screen
Reagent disk
Reaction disk
control button
Sample holder
Printer
On/Off
Figure 2-1. Analyzer overview
Touch screen: Display information and accept input from the operator to operate the instrument.
Reagent disk: For placing the reagents and providing a relatively low-temperature, stable
environment
Reaction disk control button: Control the rotation of the reaction disk to facilitate the operator to
replace the reaction cuvette.
Sample holder: For placing various types of sample containers.
Printer: Print inspection results, QC results and other information.
On/Off button: Control button for power on, power off, and logout functions.
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Back view
Power supply cooling fan
Power switch
Power socket
RJ-45 Port
COM
USB Port
Plunger pump window
Water tubing Water sensor connector

Water tubing Waste sensor connector
Waste water tubing
Power supply cooling fan: Component comes with the power supply, used for heat dissipation during
operation.
Power switch: The main power switch of the device controlling the power on/off.
Power socket: Power cord insertion position.
RJ-45: Connect to external PC for transmitting various test data.
COM: Serial port used for connecting to external PC.
USB: For external barcode reader or USB flash drive software upgrading.
Plunger pump window: For observing the operation of the plunger pump.
Water sensor connector: Connect to the water sensor
Waste sensor connector: Connect to the waste sensor
Waste tubing: Connect to the drainage path.
Water tubing: Connect to the water supply path.

6
Chapter III Components and functions
3. Chapter III Components and functions

3.1. Components
3.1.1. Reaction disk drive shaft assembly

The main function of the reaction disk drive shaft is to drive the reaction disk to a precise position,
and the operation of the three-dimensional arm enables the sample to be accurately added to each
cuvette. The initial position during the movement of the component is determined by the block on the
code wheel and the corresponding sensor, and the subsequent operation is determined by the number
of steps of the software-controlled rotation of the motor.
7
Metal block
3.1.2. Reaction plate

The main function of the reaction plate is to fix the cuvette and provide a constant temperature
environment for the entire reaction process to ensure the accuracy and stability of the instrument. The
precise control process is that the temperature information sent by the sensor, and the software
determines whether the heater wire needs to be electrified. When the temperature is lower than the set
range, the main board electrifies the heating wire, and the generated heat is transmitted to the rotating
disk, the reaction cuvette, and finally the liquid in the cuvette is heated. During this process, if the
sensor/software/main board fails, the heater wire may be electrified all the time. When heated to a
certain temperature, the temperature switch will automatically disconnect to avoid burning the reaction
disk.
Pre-embedded heating wire at the

bottom of the rotating disk
8
3.1.3. Optical module

The optical assembly is the core component of the instrument, which contains halogen lamps (light
sources), right-angle prisms, Plano-convex lenses, heat shields, rear optical systems, photoelectric
acquisition boards and other components. The precise process is that a stable light source is provided
by the halogen lamp, and when the light passes through the right-angle prism, the prism deflects the light
by 90° into the first Plano-convex lens. The lens collects the light into a point and then passes the light
through the heat shields to enter the second lens. The second lens re-refracts the light into parallel rays,
and finally enters the third lens and is reassembled into a point to enter the rear optical system for
detection. The rear optical system transmits the signal to the photoelectric acquisition board for
processing, and finally uploads the signal to the main board for analysis and produce the corresponding
result.
Including halogen
Including rear optical system,
lamp, right angle prism,
photoelectric acquisition board
Plano-convex lens, heat
shield
Contains two
lenses
3.1.4. Reagent disk cooling module

The main function of this module is to fix the reagent bottle, ensuring that the operator can place the
reagent bottle in the same position each time. At the meanwhile, the module also provides a relatively
stable low-temperature environment, ensuring that the reagent can be used normally and effectively
during the effective period, promising the detection result is accurate and stable.
The specific action process of the components in the instrument is as follows: the Peltier plate is
divided into front and back sides, one for cooling and the other for heat dissipating. The cooling side is
closely attached to the reagent disk, and the heat dissipating side is closely attached to the radiator.
During the operation, the fan removes the heat from the radiator, producing a cooling effect. Real-time
monitoring of integrated sensors and software control maintain the chamber at a specific temperature
range.
9
Pre- embedded
sensor in the middle
of the reagent disk
Radiator
Peltier plate
Cooling fan
3.1.5. Probe outer washing module

The components are mainly used to provide a clean environment for the sample probe to ensure
that the sample and reagent are not contaminated. At the same time, the inside of the module is
equipped with silicone gel, which can be used to expel the bubbles from the pipelines to ensure the
accuracy of sampling and the liquid level detection function.
Silicone gel inside
Distilled water pipeline
Waste water pipeline
3.1.6. Pump
The pump module consists of two 600ml diaphragm pumps, a 300ml rotary pump, two stepper
motor drives, one confluence block and one lower interface. The operation of each component can be
described by taking the cleaning sample probe as an example: when the sample probe needs cleaning,
10
it is first moved to the position of the washing well, then the software controls the diaphragm pump and
the solenoid valve to supply the distilled water to clean the inner wall of the probe. At the same time, the
water supplied by the rotary pump is controlled to clean the outer wall of the sample probe in the
cleaning position. The waste water flows through the washing well to enter the confluence block, and
finally the other diaphragm pump draws the waste water from the confluence block to the waste water
tank to complete the entire cleaning process.
Diaphragm pump (for Rotary pump

clean water)
Confluence box
Diaphragm pump (for
waste water)
Lower interface
Driver
3.1.7. Touch screen

When the instrument is working, the screen shows the corresponding interface and information for
the convenience of the operator to operate, which is the core part of human-computer interaction. The
component equipped with a touch panel inside, thus sample test, calibration, quality control, information
viewing, software upgrade and other operations can be easily controlled by clicking the corresponding
position of the screen according to the information displayed on the interface.
Touch panel
and display
11
3.1.8. Front cover

The components consist of a thermal printer control board, a printer head, and On/Off switch
buttons. The thermal printer control board receives the commands from the upper board to printed
various information through the printer. The switch mainly controls the power on/off of the instrument and
the logout operation of the account (Note: the power on/off function of the switch can only be used for
some functions of the instrument, and cannot cut off the power of the instrument. When necessary turn
off the power switch on the back of the instrument).
On/Off
switch button
Printer head
Thermal printer
control board
3.1.9. Sample tray holder

The holder contains a light panel, a sensor board, and a reaction disk control button. The internal
sensor board mainly detects whether the sample tube is placed in the sample holder, and uploads the
detected information to the main board, and also controls the LED light on the light board to transmit
information to the outside by on/off/flashing. The function of the reaction disk control button is to control
the rotation of the reaction disk, for the convenience of the operator to replace each reaction cuvette and
increase operation convenience.
Reaction disk
control button
Sensor board inside
Light board inside
12
3.1.10. YZ axis movement module

The module are mainly composed of a Y-axis and a Z-axis. Each of the axes is equipped with a
metal block and a sensor. With the control of the software, the Y-axis and the Z-axis can accurately
determine the origin position each time, then the software controls the motor to rotate specified number
of steps to determine the specific position of the Y and Z axes.
Y axis origin block Y axis origin sensor
Z axis origin sensor
Y axis origin block
3.1.11. Driver protect shell

The components are mainly composed of a solenoid valve and a cooling fan. The internal solenoid
valve mainly controls the on/off of the intra-probe circulation. The fan mainly dissipates heat from the
dust cover to reduce the temperature of the dust cover.
Cooling fan
Solenoid valve
13
3.1.12. Plunger pump module

The plunger pump is the core component to ensure the accuracy of the system's absorbing or
dispensing. With the operation of the diaphragm pump and solenoid valve, the plunger pump can
accurately absorb or discharge/ dispense quantitative liquid to ensure test accuracy and stability.
Piston rod
Plunger pump
14
3.2. Program content:

3.2.1. Instrument power on self-test
1) Connect the instrument to a 3-hole power socket with a power cord, turn the power switch on the
back of the instrument to the "On" state, and then press the "On/Off button" in the lower right corner
of the front of the analyzer to let the analyzer boot and complete the self-test work.
Figure 3-1
2) After the analyzer is turned on, the login dialog box will pop up first, as shown in the Figure below.
Factory account must be logged in for calibration: account: FAdmin, password: FA123456789, as
shown in Figure 2; click "Login" to enter the “self-check” interface As shown in Figure 3; click
"Confirm" then instrument would enter the self-check program; after the self-check is completed,
click "Complete" to enter the main interface as shown in Figure 4.
Figure 3-2
15
Figure 3-3
Figure 3-4
3.2.2. Mainboard Power Supply Voltage Test:

The measured voltage corresponding to “24 V” on the main board J10 is 24±1.2 V.
3.2.3. Reaction disk position calibration

1) Click Maintenance -> Adjust -> Reaction disk to enter the Reaction disk calibration interface (The
Reaction disk cover must be closed when calibrating).
2) As shown in Figure. 5, by adding or minus the number of reaction disk steps, make the position 1
cuvette centered in the reaction disk cover liquid hole; click the "Save" button to save the current
calibration position.
16
By adding or minus the number of

reaction disk steps, make the
position 1 cuvette centered in the
reaction disk cover liquid hole The cuvette number 1 shall align with the hole
for liquid adding in the reaction disk cover.
2 Note: The reaction disk cover must be closed
Figure 3-5
3) Reaction disk calibration position confirmation: Click Maintenance -> Test ->Combine ->Choose
cuvette ->Choose cuvette number ->Cuvette, as shown in Figure 6; select the cuvettes 1, 21, 41,
and 61 respectively to see if they meet the requirements of the last step.
Figure 3-6
17
3.2.4. Sample probe-washing well position calibration

1) Click Maintenance ->Adjust ->Sample probe ->Clean to enter the sample probe washing well
calibration interface, as shown in Figure 7.
Manually rotate the

stirring motor; the
arc of the sample
3 probe movement
1 shall be at the middle
2 of the washing well.
Sample probe Z-axis depth: The

4
upper edge of the black circle on
sample probe is parallel with the
panel chamfer.
Figure 3-7
2) Sample probe-cleaning position calibration (X, Y, Z): Click the X or Y or Z direction as shown in Figure
7 and add or minus the number of motor steps of the sample probe to meet the requirement. Click
“Save” to save the calibration position (X:+Left,-Right; Y:+Front,-Back; Z:+Up, -Down )
3) Sample probe-cleaning position confirmation: perform step 1) to check whether the sample probe
cleaning position is normal.
3.2.5. Sample probe-reaction cuvette position calibration

1) Click Maintenance ->Adjust ->Sample probe ->Reaction Cuvette to enter the Sample
probe-reaction cuvette position calibration interface, as shown in Figure 8 (Note: Make sure the
cuvette is clean and free of liquid during calibration).
2) Sample probe- reaction cuvette position calibration (X, Y, Z): Click the X or Y or Z direction as shown
in Figure 8 and add or minus the number of motor steps of the sample probe to meet the
requirements. After the sample probe touches the bottom, directly minus 40 steps, as shown in Figure
8. Click “Save” to save the calibration position.(X:+Left, -Right; Y:+Front, -Back; Z:+Up, -Down )
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1
2
1 Manually rotate the stirring motor, the arc of the

sample probe movement shall be at the middle of
4 the cuvette.
2 Sample probe Z axis position：After the sample
probe touches the bottom, it is further reduced by
every 5 steps until it is reduced to 40 steps when the
tab is slightly bounced.
Figure 3-8
3) Sample probe-reaction cuvette position confirmation: Click Maintenance ->Test ->Combine ->Choose
probe cuvette->Choose cuvette number ->Probe cuvette, as shown in Figure 9, the cuvettes 1, 21, 41,
and 61 are selected respectively to see if they meet the requirements.
3
1
Figure 3-9
19
3.2.6. Sample probe-reagent disk position calibration

1) Click Maintenance ->Adjust->Sample probe ->Reagent to enter the Sample probe-reagent disk
position calibration interface, as shown in Figure 10 (Note: Make sure the Reagent bottle is clean and
free of liquid during calibration)
The direction of reagent

bottle mouth is consistent
with the icon direction
1 Before the calibration position, check whether the reagent bottle mouth
is close to the inside (normally close to the inside).
2 Manually rotate the stirring motor, the arc of the sample probe
movement shall be at the middle of the bottle.
3 Sample probe Z axis position：After the sample probe hits the bottom,
it is further reduced by 5 steps and 5 steps until it is reduced to 40
steps when the block is slightly bounced.
Figure 3-10
2) Sample probe reagent position calibration (X, Y, Z): Click the X or Y or Z direction as shown in Figure
10 and add or minus the number of motor steps of the sample probe to meet the requirements. After
the sample probe touches the bottom, directly minus 40 steps, as shown in Figure 10. Click “Save” to
save the calibration position.(X:+Left, -Right; Y:+Front, -Back; Z:+Up, -Down)
3) Probe-Reagent position confirmation: Click Maintenance ->Test ->Combine ->Reagent->Choose
number->Reagent, as shown in Figure 11; the cuvettes 1, 15, 31, and 45 are selected respectively to
see if they meet the requirements.
20
1 3
Figure 3-11
3.2.7. Sample probe-standard cup position calibration

1) Click Maintenance ->Adjust->Sample probe ->Standard cup to enter the standard cup position
calibration interface, as shown in Figure 12. (Note: Make sure the cup is clean and free of liquid
during calibration)
1
2 3 1 Manually rotate the stirring motor, the arc of the
sample probe movement shall be at the middle
of the cup.
2 Sample probe Z axis position：After the sample
probe touches the bottom, it is further reduced
4 by 5 steps and 5 steps until it is reduced to 40
steps when the tab is slightly bounced.
Figure 3-12
2) Sample probe-standard cup position calibration (X, Y, Z): Click the X or Y or Z direction as shown in
Figure 13 and add or minus the number of motor steps of the sample probe to meet the requirements.
Click “Save” to save the calibration position (X: +Left, -Right; Y: +Front, -Back; Z: +Up, -Down).
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3) Sample probe-standard cup position confirmation: Click Maintenance ->Test ->Combine
->Standard -> Choose sample well type ->Choose sample position number->Standard. As
shown in Figure 13, the sample position 1, 2, 3, 4, 5 are sequentially selected to see if they meet the
requirements.
Note: After confirming the five-hole test frame, use the nine-hole test frame to confirm the relevant
position. The nine-hole mode is needed when using the nine-hole test frame.
1
2
4
3
Figure 3-13
3.2.8. Sample probe-Micro cup position calibration

1) Click Maintenance ->Adjust->Sample probe ->Micro cup to enter the Micro cup position calibration
interface, as shown in Figure 14. (Note: Make sure the cup is clean and free of liquid during
calibration).
2) Sample probe-Micro cup position calibration (X, Y, Z): Click the X or Y or Z direction as shown in
Click “Save” to save the calibration position (X: +Left, -Right; Y: +Front, -Back; Z: +Up, -Down).
3) Sample probe-Micro cup position confirmation: Perform step 1) to check whether the sample position
of the Micro cup is normal.
22
1
3 1 Manually rotate the stirring motor, the arc
2
of the sample probe movement shall be at
the middle of the cup.
2 Sample probe Z axis position：After the
4 sample probe hits the bottom, it is further
reduced by 5 steps and 5 steps until it is
reduced to 40 steps when the block is
slightly bounced.
Figure 3-14
3.2.9. Sample probe-BCT (Blood collection tube) position calibration.

1) Click Maintenance ->Adjust->Sample probe ->BCT to enter the BCT position calibration interface,
as shown in Figure 15. (Note: Make sure the cup is clean and free of liquid during calibration)
1 Manually rotate the stirring motor, the arc

2 of the sample probe movement shall be at
3 1
the middle of the cup.
2 Sample probe Z axis position：After the
sample probe hits the bottom, it is further
reduced by 5 steps and 5 steps until it is
4 reduced to 40 steps when the block is
slightly bounced.
Figure 3-15
23
2) Sample probe-BCT position calibration (X, Y, Z): Click the X or Y or Z direction as shown in Figure 15
and add or minus the number of motor steps of the sample probe to meet the requirements. After the
sample probe touches the bottom, directly minus 40 steps. Click “Save” to save the calibration
position.(X:+Left, -Right; Y:+Front, -Back; Z:+Up, -Down)
3) Sample probe-BCT position confirmation: Perform step 1) to check whether the sample position of
the BCT is normal.
3.2.10. Sample probe-Bubble remove position calibration.

1) Click Maintenance ->Adjust->Sample probe ->Bubble to enter the Bubble position calibration
interface, as shown in Figure 16.
2
3 1 1 Manually rotate the stirring motor, the arc of the
sample probe movement shall be at the middle of
the silicone gel.
2 After the sample probe touches the bottom, it is
4 further reduced by 5 steps and 5 steps until it is
added to 40 steps when the tab is slightly bounced.
Figure 3-16
2) Sample probe-Bubble remove position calibration (X, Y, Z): Click the X or Y or Z direction as shown in
After the sample probe touches the bottom, directly minus 40 steps. Click “Save” to save the
calibration position.(X:+Left, -Right; Y:+Front, -Back; Z:+Up, -Down)
3) Sample probe-Bubble remove position confirmation: Perform step 1) to check whether the bubble
remove position is normal.
3.2.11. Light position adjustment

24
1) Click Maintenance ->Adjust->Light adjust to enter the light adjust interface; click “Read AD
(Default wavelength is 510nm) ->Read light”; adjust the number of steps (+ left, - right) in "Light
benchmark calibration" to make the light alignment exactly in the middle of the waveform, as shown
in Figure 17. The halogen lamp must pass directly through the hole of No. 71 cuvette of the reaction
disk. The reaction disk must not block the halogen light source, as shown in Figure 17.Save the
current parameters when meet the requirements.
Note: Reaction disk No.71 position should be vacant.
The red line must be in the

middle of the waveform
No.71 position
Light position adjustment Halogen lamp must pass through the

hole of No. 71 position. Aperture
3 distribution moderate, such as
uneven distribution of upper and
1 2 lower aperture must be repaired after
re-adjust.
Figure 3-17
2) Light position voltage adjustment: Adjust the light position voltage on the "Light adjustment"
interface (It is necessary to turn on the machine in advance for at least half an hour to perform Light
adjustment), as shown in Figure 18. Connect the black meter with GND and the red meter with
measuring points, and rotate the potentiometer with a straight screwdriver (decrease clockwise and
increase anti-clockwise). The voltage at each point should be in the range of 3.0- 3.1V. The
measuring points for each potentiometer are shown in Form 1.
3) After the voltage adjustment is qualified, each potentiometer should be fixed with hot-melt adhesive.
After the hot-melt adhesive is applied, the voltage of each wavelength should be measured again. If
fails, it must need re-adjustment. After the voltage adjustment is qualified, lock the protective cover
with screws.
25
Note: When adjusting the voltage, the halogen lamp must be at the center of light position, and the
reaction disk No.71 position must be empty
CH9 → R55 CH7 → R56 CH5 → R57 CH3 → R58 CH1 → R59
CH2 → R60 CH4 → R61 CH6 → R62 CH8 → R63 /

Form 1
CH2 CH4 CH6 CH8
Potentiometer
Measuring
point
Potentiometer
CH1 CH3 CH5 CH7 CH9
Figure 3-18
4) Read the photoelectric AD value (empty all the cuvettes in the reaction disk): according to
Maintenance -> Test -> Photoelectric -> Dynamic -> cycles (20 times)-> time interval (3000
MS)-> Execute. As shown in Figure 19, The AD value corresponding to each group of wavelengths is
in the range of 59000-61000, and the maximum and minimum difference is ≤200.
Note: 1-340; 2-405; 3-450; 4-492; 5-510; 6-546; 7-578; 8-630; 9-700
26
2
3
Figure 3-19
3.2.12. Stirring calibration

1) Click Maintenance->Adjust->Parameter Cal to enter into stirring calibration interface, as shown in
Figure 20. The default duty ratio is 100. Click the "Start" button and check if the stirring amplitude of
the sample probe is between 2 and 3 mm.
1 2 3
Figure 3-20
27
3.2.13. Sample tube detection calibration

1) Sample tube threshold calibration: Click Maintenance->Adjust->Parameter Cal to enter into sample
position detection calibration interface. When the sample tray is vacant, click “read current value” →
input the threshold value to the sample column (sample positions 1, 2 plus 100 on the empty tube AD
value, and sample positions 3, 4, and 5 plus 1600 on the empty tube AD value) → Click "Save
Setting Value", as shown in Figure 21; If the AD value > threshold value, the blood collection tube is
detected, if the AD value < threshold value, there is no blood collection tube.
2
3
Figure 3-21
2) Sample tube detection confirmation: Click Maintenance->Test->Sensor status to enter the “Sensor
status” checking interface. Put the blood collection tube on the sample tray, the indicator light
corresponding to the sample position will flash three times, as shown in Figure 22; the corresponding
sensor status interface will show "Yes" when test tube is placed in the sample position; when the
sample tray detects no blood collection tube, the sample position will show "None". Test each sample
position in turn, as shown in Figure 22.
Note: The 9-well sample tray shall be test on positions 1, 3, 5, 7, and 9 correspond to 5-well sample
tray positions 1, 2, 3, 4, 5 from left to right.
28
"Yes" is displayed
when the test tube
is placed in the
Sample tray
corresponding
sample position,
otherwise "None"
is displayed Indicator light position
Figure 3-22
3.2.14. Reagent disk cover detection

Click Maintenance->Test->Sensor status to enter the “Sensor status” checking interface. As
shown in Figure 23, when the reagent disk cover is closed, the corresponding sensor status will display
"Yes", otherwise it will display "None". Repeat the test for three times.
"Yes" is "Yes" is
displayed displayed when
when sample reagent disk
probe cover is closed,
collides, otherwise "None"
otherwise is displayed
"None" is
displayed "Yes" is
displayed
"Yes" is
when control
displayed
button is
when sample
pressed,
probe touches
otherwise
liquid surface,
"None" is
otherwise
displayed
"None" is
displayed Figure 3-23
29
3.2.15. Sample probe anti-collision function detection

Click Maintenance -> Test -> Sensor status enter the sensor status checking interface, as shown
in Figure 23. Manually raise the sample probe (simulating sample probe crash), the probe anti-collision
display will show "Yes", otherwise "None" will be displayed, and repeat the test for three times.
3.2.16. Reaction disk control button function detection

1) Enter the “Sensor status” checking interface, as shown in Figure 23. Manually press the reaction
disk control button, the Rotation button status display will show "Yes", otherwise it will display "None",
and repeat the test three times.
2) Liquid level detection
3) Enter the “Sensor status” checking interface, as shown in Figure 23. Touch the tip of the sample
probe to the liquid surface, the corresponding liquid level should displays "Yes", otherwise it should
displays "None", and repeat the test three times.
4) Liquid level sensitive detection
5) Click Maintenance -> Test -> Liquid level detection to enter the liquid level interface, as shown in
Figure 24. The parameters should be Number of cycles: 20 times; Time interval: 1000 MS; Sample
position: 1; Sample tray: five well. The maximum and minimum AD values are ≤34.
2
3
Figure 3-24
30
3.2.17. Inlet and outlet components detection

1) Inlet pipeline module: Connect the liquid inlet module to the instrument normally, press the float
sensor, and the instrument software should prompt "Pure water is empty" to indicate that the
component is normal.
2) Outlet pipeline module: Connect the liquid outlet module to the instrument normally, lift the float
sensor, and the instrument software should prompt "Waste liquid is full" to indicate that the
component is normal.
3.2.18. Serial port detection

Connect the serial cable to the instrument serial port; open the serial debugging software on your
computer, as shown in Figure 25. Select the corresponding serial port number; click
"Connect", and press the "Enter" key on the keyboard, as shown in Figure 25.
1
Serial port
detection
OK
Figure 3-25
3.2.19. USB port detection

Insert the USB drive into the USB port and the instrument should display "Found USB drive";
Unplug the USB drive and "USB drive removed" should be displayed.
3.2.20. Net port detection
Connect the Net port with the network cable and open the LIS receiving software "gslis.exe"; Follow
the path of "setting-> network" to enter the network setting interface, as shown in Figure 26. When LIS
is connected normally, the instrument will display "LIS: ON".
3.2.21. Check cooling fans 1 and 2 on both sides of refrigeration components.
After turn on the instrument, check with your hands whether the cooling fans on both sides of the
device blow air outwards. Touch the reagent disk to check whether it is properly refrigerated.
31
7
5
6
1
3 4
Figure 3-26
3.2.22. Halogen fan detection

Visually check whether the halogen lamp fan can work normally and blow the air into the instrument;
Touch the reaction disk to see if it is heated.
3.2.23. Pump valve detection (inner pump, solenoid valve, outer pump, waste pump)
Click Maintenance ->Daily to enter the perfusion interface, as shown in Figure 27; Click
"Perfusion", then you should hear a "tick" sound of the solenoid valve; the sample probe and the
washing well will flow the liquid; the waste liquid pump should drain the liquid out.
Figure 3-27
32
3.2.24. Probe inner waterflow detection

Click Maintenance ->Test-> Combine, as shown in Figure 28. Cut a 2/32 hose of 36 ± 2 cm.
Connect one end of the hose to the sample probe port and put the other end into a 100 ml measuring
cylinder. Operating software by clicking Valve-> On-> Inner pump-> On (continuous test 1 minute) ->
All-off, and probe inner water flow rate ≥80 ml / min (Note: the" perfusion" procedure must be performed
before the inner flow rate test).
3
4
Figure 3-28
3.2.25. Printer detection

When the printer is not loaded with paper, the instrument will indicate that the printer has no paper.
Please load paper when this happens.
3.2.26. Time test

Click Setting -> Time to enter the time setting menu; the corresponding time and date can be set
normally; time and date can be saved normally after restarting the instrument.
3.2.27. S/N number input
Click Maintenance ->Test ->SN setting->SN (Input the real SN number) ->Save. After saving,
you must enter the setting interface again to confirm whether the SN number is saved.
33
Chapter IV Replacement of common parts
4. Chapter IV Replacement of common parts

4.1. Disassembly and precautions
1) To ensure the personal safety of the operator, the instrument must be turned off and the 220V power
cord must be removed before disassembling.
2) To ensure the quality of the instrument, wear protective anti-static wrist straps before disassembly.
3) To ensure the health of the operator, wear disposable rubber gloves or disposable plastic gloves
before disassembling.
4) In order to ensure the quality of the instrument, the disassembled screws, spring washers and
gaskets need to be kept safely, and should not be dropped inside the instrument. The screws with the
slipping teeth must be changed, and the screws must be tightened when assembling.
5) In order to ensure the quality of the instrument, observe the screw with the threading glue 243. After
disassembling, the threaded rubber 243 needs to be put back, and wipe the overflowed thread glue
with a paper towel.
6) In order to ensure the quality of the instrument, the straps that have been cut off during the
disassembling process must be fully plucked back, and prevent the straps from falling into the
instrument.
7) In order to ensure the quality of the instrument, where the wire needs to be removed, it is necessary
to take photos before operation to avoid incorrect wiring.
8) In order to ensure the quality of the instrument, the dismantling involves the interference of the
moving structure and the fit of the assembly clearance must be operated strictly fellow the indication,
and it must be carefully checked after the replacement step.
9) In order to ensure the quality of the instrument, any plug of the patch cord must be plugged correctly
and the hot melt adhesive is required. In principle, it must be glued.
10) During the disassembling process, be careful to avoid secondary failures caused by disassembling.
11) In order to ensure the company's image, in the process of disassembling, under the premise of
quality assurance, the operation speed should be as fast as possible, and the machine surface
should be cleaned after dismantling.
34
4.2. Instrument pipeline installation requirements

1) Before fixing the Teflon tube, the nozzle should be cut flat with a knife.
2) Twist Teflon tube into the sample probe, plunger pump and solenoid valve position, ensure that the
pipe nozzle is flush with the end of the conical head when loading.
3) The conical head joints should be screwed tightly to avoid poor sealing.
4) Teflon tube can’t be creased or squashed

The nozzle is flush with
the end of the taper
Cut the nozzle with a knife
5) After the hoses have been inserted into the solenoid valve and interface board module, it needs to be
fixed with 3*10 high quality cable tie.
Cut nozzle flat
Fixed with a cable tie

The horse is inserted
into the end
The hose is inserted
into the end
Fixed with a cable tie
The hose inserted to merely

touching the screw thread
6) The pipelines at the lower interface and the confluence block position should be directly inserted into
the bottom during installation, while it is forbidden to twist the pipeline back and forth.
Three places need to be fixed with cable tie
No need to fix with cable tie
35
4.3. Replace modules

4.3.1. Replace the pump unit
4.3.1.1. Disassembly
1) Use a Phillips screwdriver to remove the three fixing screws on the right side and pull out the right
cover backwards. As Figure 4-1 shows.
3 fixing screws
Figure 4-1
2) Use a diagonal pliers to cut off the cable tie according to the specific failure, and then pull up the two
hoses on the pump, as shown in Figure 4-2.
3) Remove the wiring at the pump position.
4) Use the Allen key to remove the fixing screw of the corresponding pump and take out the pump, as
shown in Figure 4-2. Cut off the hose fixing cable tie.
Pump fixing screws Pump pairing wiring
Cut off the hose fixing

cable tie
Pump pairing wiring
Figure 4-2
36
4.3.1.2. Assembly
1) Reassemble the pump to the plate with the removed screws, as shown in Figure 4-3.
Noted the orientation of the

pump
Figure 4-3
2) According to the arrow of the pump inlet/outlet, insert the corresponding hose into the connector.
Insert the hose to the end and fasten with 3*10 high quality cable ties, as shown in Figure 4-4.
3) Re-plug the pump wiring and insert it into the end. Figure 4-4 shows.
Inner side: Liquid outlet

Inner side: Liquid inlet
The side of the rotary pump is
the inlet port, and the middle is
the outlet port. Outer side: Liquid outlet
Outer side: Liquid inlet

Secure the
wiring
Figure 4-4
37
4.3.2. Replace the Washing well unit.

1) Use a Phillips screwdriver to remove the three fixing screws on the right side and pull out the right
cover backwards. Figure 4-5 shows.
3 fixing screws
Figure 4-5
2) Cut off the fixing cable tie at the hose position, then hold the steel pipe and pull the hose out.
3) Use an Allen key to remove the fixing screws, then rotate the washing well clockwise and slightly
bend the pipe to take out the corresponding components, as shown in 3-6.
Cut off the fixing tie, hold the steel

pipe and pull the hose back out.
Remove the fixing screw
Figure 4-6
4.3.2.2. Assembly
1) Align the components with the round holes at the panel position, and align the hoses with the round
holes on the bottom plate, then pre-tighten the components with the screws removed, as shown in
Figure 4-7.
38
2) Adjust the position of the component, make the washing well aligned with the round hole on the panel
(keep flush with the plate), and finally tighten the fixing screws, as shown in Figure 4-7.
Align the round hole
Pre-tighten with the fixing screw
Align the bottom hole position
Make the washing well aligned with the

round hole of the panel (keep flush with the
plate)
Figure 4-7
3) Insert the hose aligning the stainless steel pipe to the 8-12mm, and tighten the hose with the 3*10
high-quality cable tie (avoid damage the hose during operation), shown as Figure 4- 8.
39
Insert the hose into the steel pipe for

8~12mm, tighten the hose with the 3*10
high-quality cable tie
Figure 4-8
4) Reassemble the right side cover followed the disassemble procedures.
5) Click “Maintenance →Adjust →Sample probe” to enter the adjust interface to adjust the washing
well position and Exhaust position.
4.3.3. Replace the optical unit

1) Use a Phillips screwdriver to remove the three fixing screws on the left side and pull the left side cover
backwards.
2) Unplug the halogen lamp connector, as Figure 4-9.
Unplug the halogen lamp

connector (Blue wire)
Figure 4-9
3) Remove the 5 fixing screws on the cover and pull out the cover to the right, as shown in Figure 4-10.
40
5 fixing
screws
Remove the cover in the

direction of the arrow
Figure 4-10
4) Wipe the hot melt adhesive from the FPC socket of the photoelectric acquisition board with alcohol
cotton, and then remove the hot melt adhesive with forceps. Finally, pull out the snap-fit and take off
the cable, as shown in Figure 4-11.
Wipe the hot melt adhesive on

both sides of the socket with
alcohol cotton
Pull the buckle (black color) outward
to remove the cable
Figure 4-11
5) Use an Allen key to remove the two fixing screws on the optical unit and tilt out the optical
components, as shown in Figure 4-12.
41
Remove two
fixing screws
Figure 4-12
4.3.3.2. Assembly
1) Remove the fixing screws on the cover and then remove the high temperature adhesive tape on the
optical module, as shown in Figure 4-13.
Remove the
tape
Remove the cover
Figure 4-13
2) Align the hole to the insulation ring to tilt the optical module into the bottom plate then pre-tighten the
optical module with the removed screws. Figure 4-14 shows.
3) Adjust the position of the optical component to make it close to the edge line of the bottom plate, as
shown in Figure 4-14.
42
Push the
component inward
The optical component is close to the

edge line of the bottom plate
Figure 4-14
4) Sort the halogen lamp cable to avoid interference with the fan, then connect the wire according to the
mark, as shown in Figure 4-15.
Plug the halogen lamp connector (Blue wire),

avoid wire interfering with the fan
Figure 4-15
5) Remove the screws fixing the shielding case and take the case out rightwards. Remove the FPC unit,
then insert the cable into the socket (The blue part faces outward) to the end and fix it with
transparent hot melt adhesive, as Figure 4-16 shows.
43
Transparent hot melt adhesive is fixed

on both sides of the socket
The blue side of the cable is facing

outwards and inserted into the end
Figure 4-16
6) Connect the instrument to the power supply and turn it on, Click “Maintenance →Adjust →Light
adjust” enter the Light position adjustment interface, adjust the position of the light as required. Wait
for at least 30 minutes after adjustment and then use the multimeter to test and adjust the light
alignment voltage.
7) After adjusting and testing, the green glue should be used at the potentiometer screw positions, as
The green glue is fixed at the

potentiometer screw position
Figure 4-17
8) Re-assemble the cover according to the disassemble procedure and tighten the cover with the
removed screws, as shown in Figure 4-18.
Note: When the interference occurs during the loading process, the Hall sensor line can be
arranged to solve the interference problem.
44
Avoid damage to
the wire
Figure 4-18
9) Test the Light alignment voltage with a multimeter, and the voltage must meet the corresponding
requirements.
10) Re-assemble the left side cover with screws according to the removal procedure.
4.3.4. Replace halogen lamp

1) Use a Phillips screwdriver to remove the fixing screws on the left side cover and pull out the side
cover backwards.
2) Use an Allen key to pick out the two sealing plugs inside the reaction disk cover, and then remove the
two hexagon socket fixing screws, as shown in Figure 4-19.
Remove the sealing plugs, unscrew the

two screws, and remove the reaction disk
cover
Figure 4-19
3) Use a Phillips screwdriver to remove the four fixing screws to remove the cover, as shown in Figure
4-20.
45
Remove 4 screws
Figure 4-20
4) Remove the fixing screw from the dust cover and take out the cover, as shown in Figure 4-21.
Note: When the instrument is electrified for a long time, the dust cover will become hot.
Wait until the dust cover cooling down before disassembling.
Remove the
screw
Figure 4-21
5) Disconnect the wiring of the halogen lamp, as shown in Figure 4-22.
Unplug the halogen lamp

connector (Blue wire)
Figure 4-22
46
6) Remove the two fixing screws on the lamp holder and take out the lamp holder, as shown in Figure
4-23.
Note: When the instrument is electrified for a long time, the lamp will become hot. Wait
until the lamp cooling down before disassembling.
Remove the two fixing

screws
Figure 4-23
4.3.4.2. Assembly
1) Check the halogen lamp for stains, scratches or damages. Wipe the halogen bulb with a dust-free
cloth to ensure that the surface is clean (after cleaning, do not touch the bulb directly with hands to
avoid fingerprints), as shown in Figure 4-24
No stains, scratches
or damages.
Clean the bulb to

ensure it is clean
Figure 4-24
2) Pass the halogen lamp wire through the bottom hole, then align the slot of the lamp holder with the
pin; press the lamp holder gently to the bottom, and finally tighten the lamp holder with the two
removed screws, as shown in Figure 4-25.
47
The bulb wiring passes

through the hole
Align the slot of the lamp holder with the

pin, and press the lamp holder gently to
the bottom
Make sure the

bulb is clean
Tighten the lamp holder
with 2 removed screws
Figure 4-25
3) Align the dust cover with the groove of the front frame, and then tighten the dust cover with a screw,
as shown in Figure 4-26. Hook the dust cover to the slot at the bottom of the frame
Tighten one screw

Push the dust cover in the
direction of the arrow
The dust cover hooks the slot

at the bottom of the frame
Chamfer
Figure 4-26
48
4) Reinstall the cover into the reaction disk and tighten the cover with the four removed screws, as
Tighten the 4
screws
Push the
cover inward
Figure 4-27
5) Insert the reaction disk cover into the panel, then tighten the cover with two screws, and finally tighten
the two sealing plugs in the screw position, as shown in Figure 4-28.
The reaction disk cover

is inserted into the panel
First install the set

screw and then install
the sealing plug
Figure 4-28
6) Open the movable part of the turntable and rotate the reaction disk cover manually. No interfere with
the reaction disk cover should happen during rotation. Otherwise reinstall the reaction disk cover, as
49
Ensure that no interfere with

the reaction disk cover during
rotation
Figure 4-29
7) Connect the instrument to the power supply and turn it on. Click “Maintenance →Adjust →Light
adjust” to enter the Light position adjustment interface, adjust the position of the light as required.
Wait for at least 30 minutes after adjustment and then use the multimeter to test and adjust the light
alignment voltage.
8) After adjusting and testing, the green glue should be used at the potentiometer screw position, as
The green glue is fixed

at the potentiometer
screw position
Figure 4-30
9) Re-assemble the cover according to the disassemble procedure, tighten the cover with the removed
screws
4.3.5. Replace the reaction disk original sensor

cover backwards.
2) Cut the cable fixing tie of the sensor wire with a diagonal plier, then unplug the wire to the connector,
as shown in Figure 4-31.
50
Cut the cable fixing tie

of the sensor cable
Figure 4-31
3) Use an Allen key to remove the two fixing screws on the sensor board and take out the sensor board,
Unscrew the
2 screws
Figure 4-32
4) Remove the two fixing screws on the sensor and take out the sensor, as shown in Figure 4-33.
Sensor board
Figure 4-33
4.3.5.2. Assembly
1) Place the sensor board up, and then tighten the sensor to the sensor board with the two removed
screws, as shown in Figure 4-34.
51
Sensor pin up
The sensor board slot is placed

to the right
Two fixing screws
Figure 4-34
2) Install the sensor with pins upward into the bottom plate, then pre-tighten the sensor plate with two
screws, as shown in Figure 4-35. The sensor pins should be mounted upwards.
Two fixing screws
The sensor pins are mounted upwards
Figure 4-35
3) Adjust the position of the sensor board and rotate the reaction disk to check. The original position of
the metal block is required to between the two pins of the sensor (best to adjust to the middle position
of the two pins of the sensor), and finally tighten the two fixing screws, Figure 4-36 shows.
Note: Avoid the scratching of the sensor wiring during operation.
The block is required to between

the two pins of the sensor; no
interference should happen
Figure 4-36
52
4) Rotate the reaction disk again and observe the position of the metal block. None interference is
required.
5) Tension the sensor wiring appropriately and then tighten the wire with a 3*10 high quality cable tie, as
Note: Tension the wire properly to avoid interference with the movement of the metal block.
6) Connect the sensor wiring according to the indication, as shown in Figure 4-37
Secure the
Tighten the wire with
terminal
fixing cable tie
Avoid interference between

the block and the sensor
Figure 4-37
7) Re-assemble the left side cover with screws.
4.3.6. Replace the plunger pump

cover backwards.
2) Remove the plunger pump sensor cable (J38) and cut the fixing cable tie, Figure 4-38.
Unplug the connector at

J38 position
Cut the cable tie
Figure 4-38
53
3) Pull out the 6-pin terminal of the plunger pump motor driver and the 2-pin terminal connected with it.
Use a Slotted screwdriver to unscrew the fixing knob of the 6-pin terminal and pull out the plunger
pump motor wire. Figure 4-39 shows
Unplug the terminal
Figure 4-39
4) Unscrew the three Teflon connectors on the plunger pump, as shown in Figure 4-40.
Note: Avoid damage to the Teflon tube during operation, and avoid dropping of the
conical head on the nozzle after unscrewing the joint.
Unscrew the connectors

Remove the connector
Figure 4-40
5) Cut the cable fixing ties on the magnetic ring and driver, then use the Allen key to remove the two
fixing screws on the pump module and remove the module. Shows in Figure 4-41.
54
Remove the two

fixing screws
Cut off the cable tie

Figure 4-41
4.3.6.2. Assembly
1) Re-assemble the pump assembly to the frame with the two removed screws, and avoid damage to
the optical cable during operation, as shown in Figure 4-42.
Avoid pressing or
damaging the cable
Figure 4-42
2) According to the “Instrument pipeline installation requirements”, find the installation requirements
of the Teflon tube, and adjust the position of the nozzle, then tighten the joint on the plunger pump, as
Figure 4-43.
Note: The connector should be fully tightened to avoid air leakage and water leakage.
55
Tighten the connector
Can’t bent the

Teflon tube
Insert the Hose into the joint
Figure 4-43
3) Insert the pump sensor cable into the position of the main board J38 according to the indication and
insert to the end.
4) Strip four wire ports at 4-5 mm and tighten the wire core, then insert the wire into the corresponding
position of the 6-pin terminal according to the line sequence shown in the Figure. Finally, use a slotted
screwdriver to tighten the screws clockwise to lock the wire. Figure 4-44 shows.
Inserted to the end

From left to right: brown Tighten the screws
orange red yellow
Figure 4-44
5) Secure the magnetic ring to the base plate with a high-quality cable tie, as shown in Figure 4-45.
56
Tighten the wire
Tighten the
Magnetic ring
Figure 4-45
6) Re-assemble the left side cover with screws.
7) Connect the instrument to the power supply; enter the corresponding account number and password
to enter the maintenance interface, and then perform more than three times of Perfusion and
Exhaust operations.
4.3.7. Replace the Thermal Printer Control Board

cover backwards.
2) Use a Phillips screwdriver to remove the fixing screws on the right side cover and pull out the side
cover backwards.
3) Use an Allen key to remove the four fixing screws on both sides of the front cover and gently pull out
the module. Finally, unplug the On/Off button wire and the two wires on the thermal printer control
board. As shown in Figure 4-46.
57
Remove the two

fixing screws Remove the
two fixing
screws
Unplug the three

terminals
Figure 4-46
4) Pull up the buckle on both sides of the terminal and remove the cable. Figure 4-47 shows.
5) Remove the four fixing screws on the thermal printer control board and take out the control board, as
Pull up the buckle and remove the cable
Remove 4 fixing screws
Figure 4-47
58
4.3.7.2. Assembly
1) Use a diagonal pliers to cut the connection pins on the back of the thermal printer control board. Make
sure the pins not protrude for longer than 1 mm from PCBA board, as shown in Figure 4-48.
Cut the pin so that it is no

longer than 1mm protruded
from the PCBA board
Figure 4-48
2) Re-assemble the thermal printer control board with the removed screws, as shown in Figure 4-49.
The installation direction is

same as the removal direction. Tighten 4 fixing screws
Figure 4-49
3) Observed the back of the thermal print control board from the side, the 2- pins are required not
interfere with the front cover, as shown in Figure 4-50.
The 2-Pins cannot interference

the front cover
Figure 4-50
59
4) Insert the printer cable into the FPC socket of the control board and fasten the buckle, as shown in
Figure 4-51.
Insert the cable to the end

and fasten the buckle
Figure 4-51
5) Connect the three removed terminals with wires according to the mark, as shown in Figure 4-52.
Connect 3 terminals
Figure 4-52
6) Re-assemble the front cover into the instrument according to the disassembly procedure, and then
use two screws on each side to lock the module, see Figure 4-53.
60
2 fixing screws 2 fixing screws
Each position fits closely
Figure 4-53
7) Re-assemble the left and right covers according to the disassembly procedure.
4.3.8. Replace the printer head

1) Refer to steps in 4.3.7, Remove the Thermal Printer Control Board
2) Remove the two screws on the printer's fixing block and remove the block, as Figure 4-54.
61
Figure 4-54
3) Use a Phillips screwdriver to remove the two fixing screws on the printer head to remove the printer
head, as shown in Figure 4-55.
Figure 4-55
4) Open the printer door and pull out the printer writing roller module in the direction of the notch, as
Pull out the printer

writing roller module
Figure 4-56
4.3.8.2. Assembly
62
1) Re-assemble the printer head into the front cover as shown, and tighten the printer head with two
screws. See Figure 4-57.
Tighten 2 fixing screws

The printer port should be
flush with the cover surface
Figure 4-57
2) Fixing the printer metal block with two screws, as shown in Figure 4-58.
Screws tilted upwards
Figure 4-58
3) Align to the notch on the printer door and insert the write roller into it, as shown in Figure 4-59.
Write roller gear

The roller end aligns to
end facing left
the notch on the door
Figure 4-59
4) The open/close printer door test requires the printer door to be flush with the cover when closed, and
the open/close process is smooth, as shown in Figure 4-60.
63
Make sure the open/close

process is smooth
The printer door to be

flush with the cover after
closing
Figure 4-60
5) Install the Components according to steps 3.7.2.
4.3.9. Replace the indicator light control board

1) Disassemble the front cover components according to steps in 4.3.7.
2) Wipe the transparent hot melt adhesive on both sides of FPC socket of light board with alcohol cotton,
and then pick out the hot melt adhesive with forceps. Gently pull out the buckle and unplug the cable,
Wipe the transparent hot

melt adhesive both sides
Figure 4-61
3) Use a Phillips screwdriver to remove the two fixing screws to remove the light board, as shown in
Figure 4-62｡
64
Remove 2
fixing screws
Figure 4-62
4.3.9.2. Assembly
1) Fasten the light board on the sample tray table with two fixing screws, as shown in Figure 4-63.
2) Insert the cable with the golden side facing down into the FPC socket to the end and fasten the
buckle, and finally fix with hot melt adhesive on both sides of the socket, as shown in Figure 4-64.
Tighten 2
fixing screws
Socket facing inside
Figure 4-63
Hot melt adhesive
The letters side facing outside
Figure 4-64
3) Re-assemble the front cover components, left cover and right cover according to steps in 3.7.2.
4.3.10. Replace the Sensor board

65
1) Refer to steps in 4.3.7 to remove the front cover component.
2) Use an Allen key to remove the three fixing screws on the fixing block, as shown in Figure 4-65.
Remove the 3
fixing screws
Figure 4-65
3) Remove the three fixing screws on the sensor board and take out the sensor board. Figure 4-66
shows.
Remove the 3
fixing screws
Figure 4-66
4.3.10.2. Assembly
1) Check the position of five tubes on the sensor board, and no dirt or damage in the lamp tube, as
No dirt or damage in
the lamp tube
Figure 4-67
2) Fix the sensor board on the metal block with three fixing screws, as shown in Figure 4-68.
Fixing 3 screws
Sheet metal
bends face down
66
Figure 4-68
3) Insert the sensor board into the front cover as shown in Figure 4-69.
The sensor rests on the

sample platform
Figure 4-69
4) Re-assemble the front cover components, left side cover, and right side cover by referring to steps in
4.3.7.
4.3.11. Replace the reaction disk

cover backwards.
2) Use an Allen key to pick out the two sealing plugs inside of the reaction disc cover, and then remove
the two hexagon fixing screws, as shown in Figure 4-70.
Remove the sealing plugs, unscrew the 2

screws, and remove the reaction disk cover
Figure 4-70
3) Remove the two fixing screws on the black cover and take out the cover, as shown in Figure 4-71.
67
Remove the 2
fixing screws
Figure 4-71
4) Unplug the terminals, remove the four fixing screws on the reaction disk module, and then gently lift
the reaction disk out, as shown in Figure 4-72.
Unplug the
terminals
Remove 4 fixing
screws
Figure 4-72
4.3.11.2. Assembly
1) Check the 80 round holes on the side of the reaction disk module for dust or blockage, as shown in
Figure 4-73.
No dust or blockage
Figure 4-73
2) Align the pin holes on the reaction disk module with the pins on the reaction disk drive shaft, and then
tighten the reaction disk module with the four removed screws, as shown in Figure 4-74.
68
Note: the wire in the position of the slip ring should be arranged first during operation, to
avoid crush or damage to the slip loop during the subsequent installation procedure.
Pin
Avoid pressing
the wire
Tighten 4
fixing screws
Pin hole
Figure 4-74
3) Connect the terminals and place the joints on the edge of the center hole (to avoid joint arching), as
Place the joints on the

edge of the center hole
Figure 4-75
4) Fix the black cover to the reaction disk position with two screws｡
69
5) Refer to steps in 4.3.4 to reassemble the reaction disk cover and sealing plug.
6) Reassemble the left and right side cover according to the removal procedure.
4.3.12. Hall Sensor Board replacement

1) Use a Phillips screwdriver to remove the three fixing screws on the left side cover and pull out the left
board backwards.
2) Use a Phillips screwdriver to remove the three fixing screws on the right side cover and pull out the
right board backwards.
3) Unplug the Hall sensor terminals at the driver shield position on the left side, as shown in Figure 4-76.
Unplug the terminals
Figure 4-76
4) Use an Allen key to pick out the six sealing plugs on the panel and the two sealing plugs on the
reaction disk cover (eight in total), as shown in Figure 4-77.
5) Unscrew the two fixing screws, and remove the reaction disk cover.
6) Unscrew the six fixing screws on the panel, Figure 4-77.
Pick out the sealing plugs

and remove the 8 screws
Figure 4-77
70
7) Move the three-dimensional arm components and the panel in coordination, and constantly adjust the
position of each component to slowly remove the cover, as shown in Figure 4-78.
Note: Avoid damage the sample probe during operation.
Lift the panel
Move the 3D arm and turn the

panel to the shown position
Push the probe up for a small

distance and pull out the panel
Figure 4-78
8) Cut the cable tie and remove the two fixing screws to remove the sensor board. See Figure 4-79.
71
Figure 4-79
4.3.12.2. Assembly
1) Check the surface of the Hall sensor board for no metal debris or damages, as shown in Figure 4-80
No metal debris and

damages
Figure 4-80
2) Fasten the Hall sensor board to the metal block with two fixing screws, as shown in Figure 4-81.
Tighten 2
fixing screws
Tighten the wire

Sensor board with a cable tie
installed vertically
Figure 4-81
3) Coordinate the movement of the three-dimensional arm components and the cover, load the cover
into the instrument, as shown in Figure 4-82.
72
Push the probe up a small

distance and install the panel
Move the 3D arm and turn

the panel to this position
Continue to move the 3D

arm and turn the panel to
the shown position
Figure 4-82
4) Fasten the cover to the main module with six screws, as shown in Figure 4-83.
73
Tighten 6
fixing screws
Figure 4-83
5) Connect the Hall sensor board wiring according to the mark, as shown in Figure 4-84.
The terminals are

firmly connected
Figure 4-84
6) Reassemble the left and right side covers according to the disassembly procedure.
4.3.13. Reaction disk motor module replacement

1) Use a Phillips screwdriver to remove the six fixing screws on the left and right side of the instrument
and pull out the left and right sides board backwards.
2) Refer to the steps 4.3.12 to procedures to remove the panel.
3) Remove the three fixing screws to remove the reaction disk sheath, as shown in Figure 4-85
Remove the 3
fixing screws
Figure 4-85
74
4) Loosen the tie on the magnetic ring position and pull out the 4-pin terminal on the reaction disk driver,

Unplug the
terminals
Loosen the tie
Figure 4-86
5) Remove the four fixing screws on the motor and take out the motor module, as shown in Figure 4-87
Remove 4
fixing screws
Figure 4-87
4.3.13.2. Assembly
1) Place the reaction disk synchronous belt on the synchronous wheel of the reaction disk motor module,
then install the module onto the bottom plate in the direction shown, and finally pre-tighten the
reaction disk motor module with four removed screws, see Figure 4-88.
One end of the synchronous belt is sleeved

on the drive shaft gear, and the other end is
sleeved on the motor synchronous wheel
Figure 4-88
2) Insert a reaction disk motor tooling into the reaction disk motor and the reaction disk drive shaft. Then
tighten the four fixing screws on the reaction disk motor module with an Allen key. Finally remove the
tooling, as shown in Figure 4-89.

75
Insert the tooling into the

reaction disk motor and the
reaction disk drive shaft
Avoid heading to label

Stuck in motor
position
black area
Figure 4-89
3) Insert the wiring of reaction disk motor component into the 4-Pin socket of the reaction disk motor
driver according to the number of the terminal pin, as shown in Figure 4-90.
4) Use a 3*10 high quality cable tie to secure the magnetic ring to the bottom plate. See Figure 4-90.
Terminal is
inserted in the end
Fasten the magnetic ring
Figure 4-90
5) Connect the instrument to the power supply and turn it on, Click “Maintenance →Adjust →Light
adjust” to enter the Light position adjustment interface. Adjust the position of the light as required.
Wait for at least 30 minutes after adjustment and then use the multimeter to test and adjust the light
alignment voltage.
6) Refer to steps in 4.3.11 to reassemble the reaction disk and black cover.
7) Refer to steps in 4.3.12 to reassemble the panel, reaction disk cover, sealing plug, left side cover and
right side cover.
76
4.3.14. Reagent disk refrigeration module replacement.

1) Use a Phillips screwdriver to remove the six fixing screws on the left and right side cover and pull out
the two side covers backwards.
2) Refer to steps in 4.3.12 to disassemble the panel.
3) Unplug the three terminals on the component wiring and loosen the buckle of the fixed wire, as shown
in Figure 4-91.
Loosen the buckle
Unplug the 3 terminals
Figure 4-91
4) Use a Phillips screwdriver to remove the fixing screws on both sides of the reagent disk module (four
in total) and lift the module upwards, as shown in Figure 4-92.
Note: There are wires on both sides of the reagent disk; avoid scratching the wires during
the removal of the components.
Remove 2 screws
Remove 2 screws
Figure 4-92
77
4.3.14.2. Assembly
1) Place the wiring side of the component inwards and put the wire at the slot in the middle of the fan
baffle; aim the outlet joint to the lower interface, as shown in Figure 4-93.
Align the slot when the

wire is loaded
Figure 4-93
2) Fix the component with two fixing screws on each side of the module, as shown in Figure 4-94
Tighten the
fixing screws
Tighten the
fixing screws
Figure 4-94
3) Put the component wires into the pillar position of the panel; fasten the wires with adhesive tie, and
finally connect the three wires firmly according to the numbers, as shown in Figure 4-95.
Place wires into panel

pillar position
Fasten the wires

Firmly plug
the 3 terminals
Figure 4-95
78
4) Refer to steps in 4.3.4 & 4.3.12 to reassemble the panel, reaction disk cover, sealing plug, left side
cover and right side cover.
5) Connect the instrument to the power supply and turn it on, Click “Maintenance →Adjust →Sample
probe” to enter the Sample probe position adjustment interface; refer to step 4.6 in “Chapter 2” for
details.
4.3.15. Stirring module replacement.

1) Cut the cable tie fixing the cable of stirring motor with a diagonal plier, as shown in Figure 4-96.
Figure 4-96
2) Use an Allen key to remove the two screws under the motor module, as shown in Figure 4-97.
Remove the 2 fixing screws
Figure 4-97
4.3.15.2. Assembly
1) Align the sliding sleeve with the sample probe and tighten it to the Z axis metal block with two fixing
screws, as shown in Figure 4-98.
79
Through the
sample probe
Pre-tighten the 2
fixing screws
Figure 4-98
2) Lower the Z-axis slide by about 2/3 distance, then push the probe upward to make the probe lift to the
anti-collision spring and to the limit position; release the probe to observe. The probe is required to
rebound quickly/smoothly to the initial position. Rotate the half-turn eccentric to repeat the previous
steps to test (repeat the rotation in same direction for three times to test), and the requirements of the
above steps should be met, as shown in Figure 4-99.
Push the probe

up to the limit
Lower the
and release
Z-axis slide
by about
2/3 distance
① ②
The probe can

Repeat the
bounce back to
operation step 2 – 3
the initial position
each time after the
quickly/smoothly
eccentric wheel
(the sheet metal is
rotates for 1/4 turn
attached to the
of
z-axis slider)
④ ③
Figure 4-99
80
3) Tighten the two fixing screws on the Z axis and refer to step 3.15.2. to test the probe.
4) Connect the stirring motor wire firmly, and then fasten the terminals to the Z board with a 3*10 high
quality cable tie, as shown in Figure 4-100.
Fasten the terminals
Cable tie position
Figure 4-100
5) Connect the instrument to the power supply and turn it on. After software initialization finished, log in
the engineer's account and test the sample probe position. Sample probe position calibration is
required when position deviation occurs.
4.3.16. QR code scanner replacement.

4.3.16.1. Disassembly:
1) Move the z-axis slider down to the limit position, then use the hexagon wrench to remove the three
fixing screws on the z-axis cover to take out the cover, as shown in Figure 4-101
Slide the
z-axis
slider down
to the limit
position
Remove the 3
fixing screws
Figure 4-101
2) Pull out the wire on the scanner and remove the two fixing screws with a cross screwdriver to remove
the scanner, as shown in Figure 4-102.
81
Unplug the
terminals
Remove 2
fixing screws
Figure 4-102
4.3.16.2. Assembly
1) Check the lens of the scanner to ensure that there is no dirt, scratch or damage, see Figure 4-103.
No dirt, scratch or
damage
Figure 4-103
2) Lock the scanner with two screws and connect the corresponding wiring to the scanner, as shown in
Figure 4-104.
Align the upper screw

hole for installation
Figure 4-104
82
3) Place 45 reagent bottles with QR code into the reagent disk and put to the end.
4) Connect the instrument to the power supply and turn it on. After the software is initialized, log in to the
corresponding account. Click “Reagent → Reagent disk” to enter the reagent disk interface, click
“Select All” in the lower left corner and click “Read”. Then the scanner should start to scan 45
positions. If all reagent can be normal identify, means it is qualified. Otherwise adjust the position of
the scanner or change the QR code and test again.
4.3.17. Sample probe replacement

1) Move the YZ axis to the sample tray slot and slide the Z-axis slider down approximately 2/3 distance,
Slide down about 2/3

distance for easy removal
Move to the sample

tray position
Figure 4-105
2) Pinch the top of the probe and unscrew the connector anticlockwise, as shown in Figure 4-106.
Note: After the connector is removed, avoid dropping the small conical head on the pipe
3) Pull out the wiring of the Sample probe and the liquid level detection board, as shown in Figure 4-106.
Unscrew the connector

anticlockwise
Pinch the top

of the probe
Figure 4-106
83
4) Remove the contour screw with an Allen key and take out the spring on the screw, as shown in Figure
4-107.
Remove the contour screw

(Avoid missing spring)
Figure 4-107
5) Hold the top of the probe, then move the z-axis slider down to the bottom, and finally slowly pull out
the probe upward, as shown in Figure 4-108.
Pull out the

probe upward
Move the z-axis slider

down to the bottom
Figure 4-108
4.3.17.2. Assembly
1) Check the sample probe to ensure that there is no rust, deformation, blockage, loose, solder joint fall
off or wire cover damage, as shown in Figure 4-109.
84
Ensure that there is no rust,

deformation, blockage, loose,
solder joint fall off, wire cover
damage.
Figure 4-109
2) Pass the sample probe through the hole, and the spring could be fitted into the contour screw. Finally,
use the contour screw to limit the probe to the z-axis slider, as shown in Figure 4-110.
Load from up to down
Passed through the hole
Avoid pressing the probe

metal block
Figure 4-110
3) Refer to “Instrument pipeline installation requirements" in Chapter IV to adjust the position of the
conical head, then hold the top of the probe and tighten the connector into the sample probe, as
Note: The connector should be tightened completely to avoid air and water leakage.
85
Pinch the top of

the probe
Figure 4-111
4) Insert the sample probe wire into the corresponding position on the liquid level detection board, as
Connector inserted
to the end
Figure 4-112
5) Refer to steps in 4.3.15, and the operation shall meet the requirements. On the contrary, adjust the
position of the Stirring motor module and repeat the above steps to make it meet the requirements.
6) Connect the instrument to the power supply and turn it on. After the software is initialized, log in to the
corresponding account to enter the sample probe position. If the position is deviated, sample probe
position calibration is required.
4.3.18. Screen module replacement

1) Use a screwdriver to remove the two fixing screws on the top plate and pull out the top plate
backwards, as shown in Figure 4-113.
86
Remove 2
fixing screws
Figure 4-113
2) Use a screwdriver to remove the two fixing screws near the screen position and take out the fixing
block, as shown in Figure 4-114.
Remove 2
fixing screws
Figure 4-114
3) Use a Phillips screwdriver to remove the fixing screws on the back of the screen and remove the
fixing metal block, as shown in Figure 4-115.
Remove the fixing screws

to take out the sheets
Figure 4-115
4) Use a Phillips screwdriver to remove the two fixing screws on the fixing metal bock and take out the
block, as shown in Figure 4-116.

87
Note: Do not drop the screen when loosening the screws.
Remove the two

fixing screws
Remove the two

fixing screws
Figure 4-116
5) Place a protective pad on the top of the instrument, turn the screen back and place it on the top of the
instrument, as shown in Figure 4-117.
Place protective cotton pad to

avoid scratching the screen
The flip screen is placed

on top of the machine
Figure 4-117
6) Use an Allen key to remove the five fixing screws on the back side of the display panel and pull out
the back plate outwards, as shown in Figure 4-118.
88
Remove the five

fixing screws
Figure 4-118
7) Wipe of transparent hot-melt adhesive out from the connectors with 75% alcohol cotton, and then pick
out the hot-melt adhesive with tweezers, as shown in Figure 4-119.
Wipe the connectors of

transparent hot-melt
adhesive with 75%
alcohol cotton
Figure 4-119
8) Remove the screw on the screen cable fixing block and take out the fixing block, as shown in Figure
4-120.
89
Remove the screw
Figure 4-120
9) Cut off the cable ties and unplug the connecting terminals. Finally, remove the screen, as shown in
Figure 4-121.
Cut off the

cable tie
Figure 4-121
10) Remove the fixing screws on the SD card block to remove the block, and then gently press the SD
card to the end to remove the SD card, as shown in Figure 4-122.
Remove the screws,

take out the SD card
Figure 4-122
90
4.3.18.2. Assembly
1) Check the screen components to ensure that the touch screen is not scratched or damaged, as
The touch screen is not

scratched or damaged
Figure 4-123
2) Remove the five fixing screws on the back of the screen and pull out the black panel. Figure 4-124
shows.
Remove the 5
screws
Figure 4-124
3) Remove the SD card block.
4) Insert the previously removed SD card with the letter face outwards into the SD card slot, as shown in
Figure 4-125.
5) Use two screws to pre-tighten the fixing block on the upper computer board, slightly adjust the
position of the fixing block to make it just touches the SD card, and finally tighten the two fixing
screws on the block, as shown in Figure 4-125.
91
SD card letter face outward
Just touch the SD

card
Figure 4-125
6) Pass the screen wires through the back panel of the screen, then insert each wire into the
corresponding position of the upper computer board according to the label, and insert to the end, as
Wire through the

back panel
Figure 4-126
92
7) Sort the wires so that the white mark on the cable is aligned with the metal block, as shown in Figure
4-127.
Wires cannot White mark aligned

overlap with the metal block
Tighten the fixing screw
Figure 4-127
8) Fix each wire with an appropriate amount of hot melt glue at the position of the wire connector, as
Note: Wire should be installed vertically
9) Fasten the wires with the cable tie, as shown in Figure 4-128.
Note: The wires at the position of the cable tie should not overlap, and avoid crushing the
wires.
Fixing with hot

melt glue
Fasten the wire
Figure 4-128
10) Fasten the back panel to the screen module, and then gently press the back panel around to the
end, as shown in Figure 4-129.
11) Use five screws to fasten the back panel on the screen module, as shown in Figure 4-129.
93
Tighten 5
fixing screws
6 snap-fits
are in place
Figure 4-129
12) Turn the screen over and pre-tighten the screen components on the slider with four fixing screws &
spring pads & flat pads, as shown in Figure 4-130.
Tighten 2
fixing Tighten 2
screws fixing screws
Figure 4-130
13) Lift the screen upwards, then pre-tighten the two screen metal block on the back panel of the display
panel with two screws respectively; slide the screen up and down and adjust the position of the metal
block; make it just lie on the damping slider, and finally tighten the screws, as shown in Figure 4-131.
94
Tighten 2 Tighten 2
fixing screws fixing screws
Observe the position of the

Observe the position of the metal block from this point
metal block from this point
Renderings (right) Renderings (left)
The metal sheet is lay

against the slider
The metal sheet is lay

against the slider
Figure 4-131
95
14) Slide up and down and constantly adjust the position of the screen to make it move up and down
smoothly. Tighten the fixing screws on the screen fixing plate after adjustment, as shown in Figure
4-132.
Move up and down

smoothly
Tighten the
fixing screws
Figure 4-132
15) Refer to the removal procedure to load the top plate on the instrument and then tighten the two
screws.
96
Chapter V Troubleshooting
5. Chapter V Troubleshooting
5.1. Z-axis Reset Failure
 Problem/Trouble
Reset failure
Possible cause Possible remedy

Adjust the position of the shells and wires,
1. Rail set slider interferes with other components
see 1.2.1 for more information
2. Poor wiring contact of motor, driver or sensor Check if the wire is loose
3. Rail set slider movement abnormal Apply lubricant, find more in 4)
4. Synchronous belt loose Adjust the belt, find more in 5)
5. Stepper motor damaged Replace the motor, find more in 6)
6. Driver abnormality Replace the driver, find more in 7)
7. Sensor abnormality Replace the sensor, find more in 8)
8. Main board abnormality Replace the main board
5.1.1. Maintenance process
97
5.1.2. Repair procedure

1) Check if the Z-axis guide slider interferes with the Z-axis protecting shell, and then check whether the
Z-axis origin metal block interferes with the wire at the Z-axis position, as shown in Figure 5-1.
Z-axis protecting shell
The protecting shell cannot

interfere with the movement
of the slider
Origin metal block
The cable cannot interfere the

movement of the slider
Figure 5-1
2) Check if the motor, driver, sensor terminals and wires are loose, deformed or damaged, causing poor
contact.
3) Move the z-axis slider on the condition of powered on to check whether it has a holding power. If not,
the motor is abnormal, and perform the next troubleshooting step.
(Note: This operation cannot be performed under the "sensor status" interface)
98
4) Check whether the guide rail components are stuck with dust covered; if there is any dust, clean and
apply a small amount of lubricating oil to the guide shaft, as shown in Figure 5-2.
Clean the dust and apply a

small amount of lubricating
oil to the guide shaft
Figure 5-2
5) Check whether the synchronous belt is too loose and causes motor out of step or whether the belt is
broken; if the belt is too loose, please adjust the tightness of the belt. If the belt is damaged, please
replace the synchronous belt.
6) Unplug the green terminals from the driver, and then use the multi-meter buzzer channel detect the
two wire groups (A + and A -, B + and B -) of conducting condition. If the detection fails, check whether
the contact of the terminals is good. If the connection is good but still does not work, it means that the
motor is abnormal and should be replaced directly, as shown in Figure 5-3.
The green
terminal A+、A-
B+、B-
Figure 5-3
7) Observe whether the driver indicator is normal when the instrument is turned on (Under normal
circumstances, the green light is always on and the red light is not). (1) If the driver indicator is not on,
then use the multi-meter DC channel to check whether the driver power input terminal 24V voltage is
99
normal; (2) If the 24V power input is normal, and the driver indicator light is not on or red light flashing
constantly, it indicates the drive is abnormal and can be replaced; (3) In the case that it is impossible
to determine whether the driver is abnormal, the substitution method or dial code method can be used
to exclude the situation, as shown in Figure 5-4.
a) Substitution method: Exchange two drivers with the same current, such as X axis stepper motor
driver and Y axis stepper motor driver.
b) Dial code method: Tear off the label on the driver, dial code according to the following
requirements: (i) reaction disk stepping motor driver: turn SW1, SW2, SW7, SW8 to "on", SW3, SW4,
SW5, SW6 to "off";(ii) Y axis stepper motor driver: SW6 dial "on", SW1, SW2, SW3, SW4, SW5 dial
"off";(iii) Plunger pump stepping motor driver: SW1, SW2, SW6 dial to "on", SW3, SW4, SW5 dial to
"off"; By the above dial code a high current driver can be set to a low current or vice versa.
Green light
normally on
Figure 5-4
8) Follow the steps: ①Check if there is a lot of dust on the surface of the z-axis sensor. If there is, clean
the dust with a cotton swab; ②Log into the engineer's account and Click “Maintenance →Test →
sensor status” to enter sensor status interface to check whether the sensor is normal (if the sensor is
blocked, yes will be displayed); ③Pick up the hot melt glue to measure whether the voltage of the 1st
and 4th pin of mainboard J41 is normal. When the sensor is shielded, the voltage is required to be
greater than 4.5V, and when the sensor is not shielded, the voltage is less than 0.5V, as shown in
Figure 5-5.
100
Z axis origin sensor

Measure the voltage
of the 1st and 4th pin
Figure 5-5
9) Unplug the terminals in position J41 and measure the voltage between 1&4 pins and between 2&3
pins; the voltage should be within 5 ± 0.25V.
10) Replace the main board if the problem has still not been solved.
5.2. Y axis Reset Failure

 Problem/Trouble
Reset Failure
101
5.2.1. Maintenance process:

contact.
2) Move the z-axis slider on the condition of powered on to check whether it has a holding power. If not,
the motor is abnormal, and perform the next troubleshooting step.
(Note: This operation cannot be performed under the "sensor status" interface)
3) Check whether the guide rail components are stuck with dust covered; if there is any dust, clean and
apply a small amount of lubricating oil to the guide shaft, as shown in Figure 5-6.
5) Refer to step 6) of 5.1.2 in Chapter V to measure the stepping motor, if the abnormality is found,
replace the motor directly.
6) Refer to step 7) of 5.1.2 in Chapter V to measure the driver, if the abnormality is found, replace the
driver directly.
7) Refer to step 8) of 5.1.2 in Chapter V to measure the sensor board, if the abnormality is found,
replace the sensor board directly, as shown in Figure 5-7.
102

oil to the guide rail
Figure 5-6
Y axis origin
Measure the voltage of sensor
the 1st and 4th pin
Figure 5-7
pins; the voltage should be within 5 ± 0.25V.
9) Replace the main board if the problem has not been solved.
103
5.3. X axis Reset Failure

 Problem/Trouble
Reset Failure

contact.
contact. (Note: This operation cannot be performed under the "sensor status" interface)
104
contact, as shown in Figure 5-8.

oil to the guide shaft
Figure 5-8
driver directly.
pins, the voltage should be within 5 ± 0.25V.
105
X axis origin sensor
Measure the voltage

Figure 5-9
5.4. Plunger pump Reset Failure

 Problem/Trouble
Reset Failure

contact.
106
replace the motor directly, as shown in Figure 5-10.
B+ & B-（Yellow and Red）
A+ & A-（Brown and Orange）
Figure 5-10
driver directly.
4) Log in to the engineer's account and Click “Maintenance →Test → sensor status” to enter sensor
status interface to check whether the sensor is normal (if the sensor is blocked, yes will be displayed);
Pick up the hot melt glue to measure whether the voltage of the 1st and 4th pin of mainboard J38 is
normal. When the sensor is shielded, the voltage is required to be greater than 2.31V, and when the
sensor is not shielded, the voltage is less than 0.99V, as shown in Figure 5-11.
Plunger pump
origin sensor
Measure the voltage of

the 1st and 4th pin
Figure 5-11
107
5.5. Reaction disk Reset Failure

 Problem/Trouble
Reset Failure
2. Drive shaft movement abnormal Replace reaction disk drive shaft
7. Main board abnormality Replace the main board, find more in 7)

contact.
2) Manually rotate the reaction disk component, as Figure 5-12 to check whether it is moving smoothly
in the case of power off. If it is stuck, please replace the drive shaft (refer to Step 3.13 and remove the
108
corresponding part); manually rotate the reaction disk component to check whether it has a holding
power when the power is on If not, the motor is abnormal; perform the next troubleshooting step.
(Note: This operation cannot be carried out under the interface of "sensor status")
Rotating reaction
disk test
Figure 5-12
driver directly.
Measure the voltage

Reaction disk motor

origin sensor
Figure 5-13
109
5.6. Cooling system Failure

 Problem/Trouble
Cooling system Failure
1. Sensor abnormality Replace the sensor
2. Poor wiring contact Check if the wire is loose
3. Fan/Peltier plate damage Replace the fan or the cooling module

1) Connect the instrument to the power supply and turn it on. Log in the corresponding account after the
program initialization is completed. Click the temperature area on the lower side of the screen to
display the temperature of the reagent disk; check the temperature displayed. Under normal
conditions, the temperature displayed is close to room temperature. Otherwise, proceed to the next
step, as shown in Figure 5-14.
2) Turn off the instrument and wait for three seconds; exchange the terminals position of J6 and J7.
Restart the machine to check whether the temperature is displayed normally. If the same abnormality
still occurs (Reagent disk temperature is abnormal), change the main board. Otherwise please
operate the next step, as shown in Figure 5-15.
110
Click this area to switch to

display reagent disk temperature
temperature
Figure 5-14
Exchange J6 and J7 terminals for

testing, and return to the original
position after testing
Figure 5-15
3) Remove the right panel to check the temperature sensor wire (J6). If no problem is found, replace the
refrigeration module according to the step 4.3.14 in Chapter IV.
4) Check if the J11, J12, J4 (red and black wires) terminals are loose or deformed, resulting in poor
contact.
5) Unplug the terminals at the position of J11, J12, J4 (red and black wires), and then use a multi-meter
to measure the voltage at the position of the main board, as shown in Figure 5-16. When the voltage
is within the range of 24±1.2V, please replace the reagent disk refrigeration module referring to step
4.3.14 in Chapter IV. Otherwise replace the main board.
6) When the main board is normal but cannot be cooled, please refer to step 4.3.14 in Chapter IV to
replace the reagent disk cooling module.
111
Measure the voltage
Measure the voltage
Measure the voltage
Figure 5-16
Note: (i) When the instrument is electrified for a long time, one or both sides of the reagent disk can be
hot or the temperature is obviously increased. The most possible reason is that the cooling fan is
damaged, and if the ironing time is too long, the Peltier plate may be damaged. (ii) If the cooling effect is
not good, the heat-conducting fan on both sides of the reagent disk may be damaged or the cooling fan
may be aging. At this time, replacing the corresponding fan can solve the problem.
5.7. Reaction disk heating Failure

 Problem/Trouble
Reaction disk heating Failure
1. Sensor abnormality Replace the sensor
2. Poor wiring contact of the reaction disk Check if the wire is loose
112

1) Power the instrument on and log into the corresponding account after the program initialization is
completed. Click the temperature area on the lower side of the screen to display the temperature of
the reaction disk, check the temperature displayed. Under normal conditions, the temperature
displayed is close to room temperature. Otherwise, proceed to the next step, as in Figure 5-17.
Click this area to switch

to display reaction disk
temperature
Figure 5-17
2) Turn off the machine and wait for 3 seconds, exchange the terminals position of J6 and J7. Restart
the machine to check whether the temperature is displayed normally. If the same abnormality still
occurs (Reaction disk temperature is abnormal), please operate the next step, as in Figure 5-18.
Exchange J6 and J7 terminals

for testing, and return to the
original position after testing
Figure 5-18
3) Refer to step 4.3.11 in Chapter IV to remove the terminals in the reaction disk, as shown in Figure
5-19.
4) Unplug the terminals of the J7 position of the main board.
113
Figure 5-19
5) Adjust the multi-meter to the buzzer channel, contact one of the multi-meter pen terminals to the red
wire pin of the slip ring according to the color of the wire, and the second pen contact the red wire pin
of the main board J7 position terminals; the multi-meter should continually beep, as shown in Figure
5-20. Refer to the above method to measure the two wires on the connector. Under normal
circumstances, the multi-meter will continue to beep. If no abnormality is found, please replace the
reaction disk module according to the step 4.3.11 in Chapter IV; otherwise check each wire and
replace the wiring when no abnormality is found.
The pen contacts the red and

black wires in turn for testing
Figure 5-20
6) Adjust the multi-meter to the resistance channel to test the resistance between the two blue wires of
the reaction disk module, as shown in Figure 5-21. Under normal circumstances, the resistance value
is in the range of 7.3±1Ω. Otherwise, please replace the reaction disk module.
7) Refer to step 5) to test the two wires. Under normal conditions, continuous beep sound will be emitted,
If no problem is found, please replace the reaction disk components according to 4.3.11 in Chapter
IV; Otherwise check each wires and terminals. If no abnormalities are found, please replace the slip
ring wire, as shown in Figure 5-22.
114
Measure the resistance

between two blue wires
Figure 5-21
Note: The blue wire of the slip ring position does not correspond to the blue wire at J4 position. During
operation, it is enough to detect only one of the wires conducted. Repeat the operation to test the
other blue wire.
The pen contacts the blue

wires in turn for testing
Figure 5-22
115
5.8. Waste overflow

 Problem/Trouble
Waste overflow
1. Washing well blockage Clean up the washing well
2. Waste pump damage Replace the waste pump
4. Confluence box / pipelines blockage Replace the Confluence box / pipelines


1）Check and clean the washing well to ensure that the hole is not blocked, as shown in Figure 5-23.
Three holes positions

should not be blocked
Figure 5-23
2）Click the "perfusion" button and check whether the rotating shaft of the waste liquid pump can rotate.
If not, operate the next step. If it rotates, operate step 4), as shown in Figure 5-24.
116
3）Click the "perfusion" button again and check whether the LED light at the main board J35 position can
be on. When it is on, use the Multi-meter DC voltage channel to test the voltage at the slot of the J35
terminals. If the voltage is within the range of 24 ± 1.2V, operate the next step; otherwise, please
replace the main board, as shown in Figure 5-25.
4）Check if the pump terminals are loose or deformed, resulting in poor contact. Check whether the
cable is damaged. If there is no abnormality, please replace the waste pump according to step 4.3.1
in Chapter IV.
Click Perfusion Touch the shaft and check

whether it will rotate
Click maintenance
Figure 5-24
5）If the above steps have not solved the problem, please remove the 4-foot pads at the bottom of the
instrument; slightly disassemble the bottom plate to clean the confluence box or replace the
corresponding pipeline.
Test the voltage at the slot of

the J35 terminals
Lights up
Figure 5-25
117
5.9. Rotary pump with no water supply

 Problem/Trouble
No water supply
1. Filter blockage Replace the filter, find more in 1)
3. Rotary pump damage Replace the Rotary pump, see 2) – 3)

1) Remove the filter in inlet pipeline module, click "perfusion" button in the maintenance interface and
check whether there is water flow in the pipeline. If it has flow normally, please replace the filter. If it
does not have, operate the next step, as shown in Figure 5-26.
Check whether there is

water flow in the pipeline
Figure 5-26
118
2) Click the "perfusion" button again and check whether the LED light at the main board J33 position will
be on. When it is on, use the Multi-meter DC voltage channel to test the voltage at the slot of the J33
terminals. If the voltage is within the range of 24 ± 1.2V, operate the next step, otherwise, please
replace the main board, as shown in Figure 5-27.
Test the voltage at the slot

of the J33 terminals
Lights up
Figure 5-27
3) Check if the pump terminals are loose or deformed, resulting in poor contact. Check whether the
cable is damaged. If there is no abnormality, please replace the Rotary pump according to step 4.3.1
in Chapter IV.
119
5.10. Sample tray holder overflow

 Problem/Trouble
Sample tray holder overflow
1. Sample tray holder inlet blocked Clean up the inlet
2.Pipelines/Lower interface/ Confluence box inlet Replace Pipelines/Lower interface/

blocked Confluence box
1) Take out the sample tray, check and clean the inlet position to ensure that the slot is not blocked, as
2) Remove the 4 foot pads at the bottom of the instrument, slightly open the bottom plate to clean the
confluence box or replace the corresponding pipe/lower interface.
No blockage
Figure 5-28
120
5.11. Sample probe not stirring

 Problem/Trouble
Sample probe not stirring
1. Bearing/Eccentric wheel damage Replace the stirring module
2. Synchronous belt damage or loose Replace the synchronous belt
3. Stirring motor damage Replace the stirring motor
4. Motor control board damage Replace the Motor control board

1) Rotate the eccentric wheel as shown in Figure 5-29, when the wheel is stuck or not smooth, please
replace the stirring motor module according to the step 4.3.15 in Chapter IV.
121
Rotate the eccentric wheel
Figure 5-29
2) Observe whether the synchronous belt is cracked, broken or loose. If abnormal, please replace the
synchronous belt, as shown in Figure 5-30.
Check the
synchronous belt
Figure 5-30
3) Click "read" on the parameter set interface, and then click "start" button to observe whether the
stirring motor can rotate normally. Otherwise, operate the next step, as shown in Figure 5-31.
122
Click Maintenance
Click “AdjustParameter set”
Click “ReadStart”
Check whether rotate
Figure 5-31
123
4) Click the "start" button again, and then observe whether the green indicator light on the motor control
board is normally on. When the LED light is normally on, follow 8) to operate, otherwise, operate the
next step, as shown in Figure 5-32.
The light is normally on
Figure 5-32
5) Use the multi-meter DC voltage channel to measure the position of the main board J19. When the
voltage is within the range of 24 ± 1.2V, operate the next step, otherwise replace the main board.
Figure 5-33 shows.
Measure the voltage at the

slot of the J19 terminals
Figure 5-33
6) Click the “Start” button again and then test the voltage of the J25 red wire position with the
multi-meter DC voltage channel. When the voltage is within the range of 5 ± 0.25V, operate the next
step, otherwise replace the main board, as shown in Figure 5-34.
124
Use the pen to touch the

J25 red wire terminals
Touch the fixing

screw in the lower
right corner
Figure 5-34
7) Check if the terminals are loose or deformed, resulting in poor contact. Check whether the cable is
damaged. If there is no abnormality, please replace the motor control board or stirring module (Refer
to step 4.3.15 in Chapter IV to replace the stirring motor module).
125
5.12. Unable to power on normally

 Problem/Trouble
Unable to power on normally
2. Power switch damage Replace the power switch
3. Power module damage Replace the power module, see 3) - 5)
4. Power On/Off damage Replace the Power On/Off, see 6)
5. Screen damage Replace the screen, see 7)
6. Main board abnormality Replace the main board, see 6) – 7)

1) Check if the relative terminals are loose or deformed, resulting in poor contact. Check whether the
cable is damaged.
2) Connect the instrument to the power supply, then turn the switch to the “-” end and observe whether
the green light of the switch button could light up normally. If not, the power switch should be replaced,
126
as shown in Figure 5-35. (When pressing the switch button, you may hear the "beep" sound but the
screen is not displayed, then this means the screen damage. Refer to step 4.3.18 of Chapter IV to
replace the screen components.)
Light up
Figure 12-5-35
3) Turn off the power and unplug the power cord; remove the rear panel, and then remove the protective
cover from the power module.
4) Reconnect the instrument to the power supply and turn on the power switch. Use the multi-meter AC
voltage channel to measure the voltage between the brown and blue wires (L and N). The required
voltage should be within 5% of the access voltage. Otherwise, please connect to a stable power
supply, as shown in Figure 5.36.
Measure the voltage

between L&N
Figure 5-36
5) Use the multi-meter DC voltage channel to measure the voltage between the red and black wires (V+,
V- wires) of the power supply. When the voltage is within the range of 24 ± 1.2V, operate the next step.
Otherwise, replace the power supply, as shown in Figure 5-37.
127
Measure the voltage

between one of V+&V-
Figure 5-37
6) Use the multi-meter buzzer channel to measure the two pins of the J2 terminals. If the multi-meter
emits a “beep” sound, please replace the On/Off Switch; long press the On/Off Key, if the multi-meter
continues to emit “beep” sounds, please replace the main board. As Figure 5.38 shows.
Red and black pens touch

each metal contact for testing
On/Off Switch
Figure 5-38
128
7) Use the Multi-meter DC voltage channel to test the voltage at the slot of the J17 terminals. If the
voltage is within the range of 24 ± 1.2V, refer to step 4.3.18 in Chapter IV steps to replace screen
module; otherwise, please replace the main board, as shown in 5-39.
Test the voltage at the

Figure 5-39
5.13. Sample probe crash

 Problem/Trouble
Sample probe crash
1. Poor wiring contact Check if the wire is loose or damaged
2. Check if the wire is loose Replace the spring, see 2)
3. Replace the spring Clean the sensor
Replace the liquid level detection board, see

4. Liquid level detection board damaged
4) – 6)
129

contact.
2) Check the spring above the sample probe, and ensure there is no deformation; otherwise, replace the
spring, as shown in Figure 5-40.
No deformation
of the spring
Figure 5-40
3) Check the position of the sensor, and there is no dirt or debris blocking the sensor. Otherwise, clean
the position of the sensor, as shown in Figure 5-41.
Check the
sensor
Figure 5-41
130
4) Turn on the machine and enter the main interface. If the indicator on the liquid level detection board is
on, proceed to the next step. Otherwise, operate step 6). Figure 5-42 shows.
Indicator light
Figure 5-42
5) Enter the sensor status interface. By default, the position of the probe will display “None”. Raise the
probe up for a small distance and observe the anti-collision indicator light. When the red indicator light
of the liquid level detection board lights up and the sensor status interface of the probe shows “None”,
please replace the main board; when the red indicator light of the board does not light up and the
sensor status interface of the probe shows “None”, please replace the liquid level detection board, as
131
Click Test
Click Sensor status
Default display “None”
Anti-collision
indicator light
Raise the probe up a

small distance
Figure 5-43
132
6) Unplug the terminals at the position J30 of the main board and measure the voltage between the 2nd
and 4th pins (V/G) with the multi-meter DC voltage channel. When the voltage is in the range of
5±0.25V, replace the liquid level detection board. Otherwise, replace the main board. Figure 5-44
shows.
Measure the voltage

of the 2nd and 4th
pin
Figure 5-44
133
5.14. Liquid level detection abnormality

 Problem/Trouble
Liquid level detection abnormality
1. Bubbles in the pipelines Apply 'Exhaust' in the 'Maintenance' interface
3. Sample probe damaged Replace the sample probe
Liquid level detection board damaged, see 4)

4. Liquid level detection board damaged
- 6)

1) Enter the “Maintenance” interface, operate the Exhaust and check whether the problem is solved, as
Click Exhaust to remove

the bubble in the pipeline
Figure 5-45
134
damaged.
3) Check the sample probe to ensure that there is no rust, damage or looseness. Otherwise, replace the
sample probe, as shown in Figure 5-46.
Figure 5-46
4) Power on and enter the main interface. If the power indicator light on the liquid level detection board
is on, operate the next step; otherwise, operate 6), as shown in Figure 5-47.
Indicator light
Figure 5-47
5) Enter the sensor status interface. By default, the position of the Liquid level will display “None”. Put
the sample probe in contact with the liquid and observe the liquid level indicator. At the moment of
contact with the sample probe, if the blue indicator light of the liquid level detection board lights up
and the position of the interface liquid level shows "None", please replace the main board. When the
blue indicator light of the liquid level detection board is not light up and the liquid level position also
shows "None", please replace the liquid level detection board, as shown in Figure 5-48.
135
Click Test
Click sensor status
Default display “None”
Liquid level detect

indicator light
Sample probe
touch the liquid
Figure 5-48
136
6) Unplug the terminals at the position of the main board J30 and measure the voltage between the 2nd
5±0.25V, replace the liquid level detection board. Otherwise, replace the main board. Figure 5-49
shows.
Measure the voltage

of the 2nd and 4th pin
Figure 5-49
137
5.15. Reaction disk not responses when press the disk control button
 Problem/Trouble
Reaction disk not responses when press the disk control button
2. Disk drive shaft/Driver/Motor damaged Replace the damaged component
Replace the reaction disk control button,

3. Reaction disk control button damage.
see 1)

cable is damaged.
2) Unplug the terminals at the position of the main board J43, and then measure the 1st & 4th pin with
the multi-meter buzzer channel. By default, the multi-meter does not emit “beep” sounds, otherwise
change the switch. Long press the control button, if the multi-meter continues to emit "beep" sounds,
replace the motherboard, otherwise replace the control button, as shown in Figure 5-50.
138

the 2nd and 4th pin
Press the
Button to test
Figure 5-50
139
5.16. No liquid dispensing from the sample probe

 Problem/Trouble
No liquid dispensing from the sample probe
1. Filter blockage Replace the filter
3. Pipelines blockage Check/Replace pipelines
4. Sample probe blockage Unblock the probe, see 4)
5. Pump damage Replace the pump, see 8)
6. Solenoid valve damaged Replace the solenoid valve, see 9)

1) Remove the filter, click the "Perfusion" button in the maintenance interface and check whether the
water in the pipeline could flow. Please replace the fuel when it can flow normally, or operate the next
step when it cannot, as shown in Figure 5-51.
140
Check whether the water flow

in the pipeline could flow
Figure 5-51
damaged, if no, proceed the next step.
3) Check whether any pipeline is blocked, operate the next step if not, or replace the blocked pipeline,
Figure 5-52
4) Insert the needle into the sample probe from the tip as shown in the Figure, and unclog the probe
back and forth (the needle is stored on the last page of the manual), and then perform the next step,
Figure 5-53
141
5) Enter the “Combine” interface, click the on/off button on the side of the inner pump and waste pump
to start the pump up; touch the pump inner motor shaft, and operate the next step when it is normally
rotated. Otherwise, operate step 8). Shown as Figure 5-54.
Click on these two places to

make them show “Off”
Touch the shaft to check

whether it is rotating
Figure 5-54
6) Click the on/off button on the side of the valve to open the solenoid valve. If the "tick" sound can be
heard during the click, operate the next step; otherwise, operate step 9), as shown in Figure 5-55.
7) Note: the duration of solenoid valve being open should not be too long, to avoid damage to the
solenoid valve.
142
Click to show “Off”
Figure 5-55
8) Unscrew the pipeline in the position of solenoid valve, then put appropriate amount of tissue at the
outlet position, and click the on/off button on the side of the valve and the inner pump. If the solenoid
valve position can drain normally, reconnect the pipeline according to the requirements in 4.2 of
Chapter IV, otherwise replace the solenoid valve, as shown in Figure 5-56. (Note: pump/valve should
not be turned on/open for too long, to avoid water leakage or damage to the bottom driver)
Put the tissue at the

outlet position
Unscrew the connector
Avoid water leakage and

damage to the driver
Figure 5-56
voltage is within the range of 24 ± 1.2V, replace the diaphragm pump refer to step 4.3.1 in Chapter IV,
otherwise, please replace the main board, as shown in Figure 5-57.
143
Test the voltage at the slot

of the J34 terminals
Lights up
Figure 5-57
voltage is within the range of 24 ± 1.2V, replace the solenoid valve, otherwise, please replace the
main board, as shown in Figure 5-58.
Test the voltage at the

Lights up
Figure 5-58
5.17. Touch screen abnormality

 Problem/Trouble
Touch screen abnormality
1. Screen position calibration offset Re-calibrate the screen
2. Screen compressed by foreign object Clean the foreign object
4. Screen damage Replace the screen
144

1) Click “Setting →Cal →Cal Touch”; according to the instructions, click the center of the 5 cross-star
points to recalibrate the screen, as shown in Figure 5-59.
Click Setting
Click Cal
Click Cal Touch
Click the 5 cross stars

center
Figure 5-59
2) Check around the screen. No hard objects should be on the screen, as shown in Figure 5-60.
145
No foreign objects
should be on the screen
Figure 5-60
damaged. If there is no abnormality, please replace the screen module (Refer to step 4.3.18 in
Chapter IV to replace the screen module).
146
5.18. USB Flash Drive unrecognized

 Problem/Trouble
USB Flash Drive unrecognized
1. USB Flash Drive damaged Replace the USB Flash Drive
3. Poor contact of the USB port Replace the interface board
4. Interface board damaged Replace the interface board
5. Upper main board damaged Replace the upper main board

1) Use another instrument or PC to test the USB drive; please replace the USB drive if it is damaged.
2) Check if the relative terminals are loose, oxidized or deformed, resulting in poor contact. Check
whether the cable is damaged. If normal, operate the next step.
3) Observe the position of the USB port. When damage / rust occurred, replace the interface board, as
No rust / damage
Figure 5-61
147
4) Check the position of the USB port on the interface board. Please replace the port if it is damaged, as
No short circuit
or damage
Figure 5-62
5) If the above method does not solve the problem, please replace the screen components according to
step 4.3.18 in Chapter IV.
148
5.19. Unable to connect to LIS

 Problem/Trouble
Unable to connect to LIS
1. Parameters setting error Reset the parameters, see 1)
3. Connector pins oxidized Clean the oxide layer, see 3)
4. Poor contact of the net port Replace the interface board, see 4)
5. Interface board damage Replace the interface board, see 5)
6. Replace the upper main board Replace the upper main board

1）Check the setting parameters to ensure that the settings are correct:
a) Click Setting to enter the setting interface.
149
Click Setting
LIS connection
status
Figure 5-63
b) Set the host IP and connection port according to the connected computer, and finally click Save,
c) Set the instrument's IP address, sub-gateway mask, and default gateway. Click save button
after setting and Restart Network, as shown in Figure 5-65.
Click Network
Input Host IP
address
LIS connect port
Figure 5-64
150
Ensure that the IP is in the same gateway as the

computer IP and no conflict with the IP address
Setting subnet mask
Make sure the instrument IP and

Default computer IP are under the gateway
Figure 5-65
2）Check if the relative terminals are loose or deformed, resulting in poor contact. Check whether the
cable is damaged.
3）Pull out each crystal connector and check the position of the contact pins. There should be no
oxidation defect. Otherwise, use the eraser to remove the oxidation layer, as shown in Figure 5-66.
Use the eraser to

remove the oxidation
layer
Use the eraser to

remove the oxidation
layer
Figure 5-66
4）Check the net port position. Clean the interface port in case of blockage. Replace the interface board
if it is deformed or damaged, as shown in Figure 5-67.
151
Net port not blocked,

deformed or damaged
Figure 5-67
5）Check the position of the interface board, there should be no short circuit or damage, as shown in
Figure 5-68.
No short circuit / breakage

on PCBA board
Figure -5-68
6）If the above method does not solve the problem, please replace the screen components according to
152
5.20. Printer abnormality

 Problem/Trouble
Printer abnormality
1. Writing roller/Printer damaged Replace the damaged component
3. Printer control board damaged Replace the printer control board
4. Main board damaged Replace the main board
5. Upper main board damaged Replace the upper main board

1) Check if any blockage or damage occurred on the rubber column of the printer's writing roller module,
and check the position of gears, as shown in Figure 5-69.
No damage to gears
The rubber column is free or tooth blockage
from dirt and damage.
Figure 5-69
2) Check the gears of the printer. There should be no clogging foreign objects or gears damaged, as

153
No damage to gears
or tooth blockage
Figure 5-70
3) Check the printing side of the printer and ensure no dirt and damage, as shown in Figure 5-71.
No dirt and damage
Figure 5-71
4) Gently press the printer door to see if it can print normally. If printing normally, please reinstall the
printer head according to 4.3.8 in Chapter IV, as shown in Figure 5-72.
Press the printer door

gently to test
Figure 5-72
damaged.
154
6) Remove the front cover module according to 4.3.7 in Chapter IV and check the
thermal-printer-control panel indicator. If it can flash normally, operate step.8), otherwise go to the
next step, Figure 5-73 shows.
Light blinks
normally
Figure 5-73
7) Unplug the terminals at the position of the main board J22 and measure the voltage between the 1st
5±0.25V, replace the printer control board refer to 4.3.7 in Chapter IV. Otherwise, replace the main
board. Figure 5-74 shows.

the 1st and 4th pin
Figure 5-74
8) If the above method does not solve the problem, please replace the screen components according to
Note: Take a printer head for backup during operation.
155
5.21. Communication Timeout

 Problem/Trouble
Communication Timeout
1. Wiring loose/damaged Check the wires
2. Component damaged Replace the damaged components
3. Main board damaged Replace the main board
4. Upper main board damaged Replace the screen module

cable is damaged.
2) Remove all the wires on the main board other than J56, and operate the next step in case of repeated
communication timeout. Otherwise, specific damaged parts can be found by continuously reconnect
wires in turn to the mainboard, as shown in Figure 5-75.
156
Only J56 left, unplug

other wires for testing
Figure 21-5-75
3) Replace the main board. If problems still exist, replace the screen components according to 4.3.18 in
Chapter IV.
5.22. Indicating light failure

 Problem/Trouble
Indicating light failure
1. Parameters setting error Reset the parameters, see 1)
3. Main board abnormality Replace the main board, see 3)
4. Sensor control board abnormality Replace the sensor control board, see 3)
5. light control board abnormality Replace the indicating light control board
157

1）Check all parameters and reset when abnormal:
a) Take out the test tubes on the sample tray, as shown in Figure 5-76.
Take out the 5- well

sample tray
Figure 5-76
b) Enter the Adjust interface. Click “Parameter set Read current”, as shown in Figure 5-77.
Read initial
value
Figure 5-77
158
c) The threshold value of position 1 & 2 is obtained by adding 100 to the initial value. Add 1600 to
the initial value for position 3 to 5 to get the threshold value. Enter the corresponding threshold value
in the corresponding position, and finally click Save, as shown in Figure 5-78.
Set the corresponding

threshold value
Figure 5-78
d) Click Read setting and check whether it is correspond with the set threshold value.
2）Check whether the FPC cable is damaged; whether the FPC socket is short circuit or damaged.
3）Take out the cable at position J61 of the mainboard. Use a multi-meter DC voltage channel to test the
voltage of FPC socket position on the main board. If the voltage of the pins in number
1/2/3/14/15/16/17/18/19/20/21/22 is in the range of 3.3 ± 0.165V, the 4/5/6/7 pins are connected to
the ground, and the voltage of pins 8/9 is in the range of 1.3 ± 0.3V, the voltage of pins 10/11/12 is 0V,
and voltage of 13th pin is in the range of 3.2 ± 0.16V, then please replace the sensor board according
to 4.3.10 in Chapter IV, otherwise replace the mainboard, as shown in Figure 5-79.
Use Black pen to

contact the fixing
Red pen contact each
screw
pins for testing
Figure 5-79
4）If the above method does not solve the problem, please replace the light control board according to
159
5.23. Insufficient clean water

 Problem/Trouble
Insufficient clean water
2. Connector smudged/blocked/oxidized Clean the connector
4. Inlet pipelines damaged Replace the Inlet pipeline component
5.23.1. Repair process

1）Check if the relative terminals are loose or deformed, resulting in poor contact. Check whether the
cable is damaged.
2）Check the connector pins to ensure that the socket is free from dirt, oxidation and blockage, as
shown in Figure 5-80. No blockage
No dirt, oxidation,
blockage
Figure 5-80
3）Unplug the wire at the position J9 of the main board and measure the voltage between the 3rd & 4th
pin with the DC voltage channel of the multi-meter. Under normal conditions, the voltage is within the
range of 24 ± 1.2 V. Otherwise, replace the main board. Short circuit the 3rd & 4th pins and measure
the voltage again. If the voltage is 0V and the LED light on D5 lights up normally, replace the liquid
inlet pipeline component; otherwise, replace the main board, as shown in Figure 5-81.
160
Measure the voltage

between the two pins of
the liquid level sensor
LED lights up when
shorted the pins 3rd &4th
Figure 5-81
5.24. Waste water is full

 Problem/Trouble
Waste water is full
2. Connector smudged/blocked/oxidized Clean the connector
4. Inlet pipelines damaged Replace the component

cable is damaged.
No blockage
No dirt, oxidation,
blockage
Figure 5-82
161
2) Check the connector pins to ensure that the socket is free from dirt, oxidation and blockage, as
3) Unplug the wire at the position J9 of the main board and measure the voltage at the 1st & 2nd pins
with the DC voltage channel of the multi-meter. Under normal conditions, the voltage is within the
range of 24 ± 1.2 V. Otherwise, replace the main board. Short circuit the 1st & 2nd pins and measure
the voltage again. If the voltage is 0V and the LED light on D5 is light normally, replace the liquid inlet
pipeline component; otherwise, replace the main board, as shown in Figure 5-83.
Measure the voltage

between the two pins of LED lights up when
the liquid level sensor shorted the pins 1st & 2nd
Figure 5-83
5.25. Self-test abnormal

 Problem/Trouble
Self-test abnormal
1. Communication Self-test abnormal See 21 Communication Timeout
2. QR code scan abnormal Replace the QR code
Replace the photoelectric component,

3. Photoelectric value unstable
see 4.3.3
4. The intensity of light is dissatisfy Replace the halogen light, see 4.3.4
5. Reaction cuvette information abnormal Replace the optical module, see 4.3.3
6. Temperature abnormal See 6Reaction disk heating Failure
162

cable is damaged.
2) Unplug the wire at the position J57 of the mainboard and measure the voltage between the 1st & 4th
pins with the DC voltage channel of the multi-meter. If the voltage is within the range of 5 ± 0.25 V,
replace the scanner by referring to 4.3.16 in Chapter IV. Otherwise, replace the mainboard, as
Note: There are limitations in measurement, and the communication point cannot be
measured. Mainboard and QR code scanner materials should be prepared during
maintenance.

the 1st and 4th pins
Figure 5-84
163
Error code and explanation
6. Error code and explanation

N1 The concentrations of all the calibration points are 0
N2 During two-point calibration, the concentrations or the responsiveness are the same
N3 Calculation or parameter error is returned when generating the calibration curve by algorithm.
N4 Calculation or parameter error is returned when calculating the concentration by algorithm
N5 The calculated concentration is abnormal
N6 The average deviation is more than 10%
N7 Wrong calibration rule
N8 The repeatability is bad in the same calibrator when repeat times is more than 1
NS Sample is not sufficient
NR Reagent is not sufficient
SR Lack of samples and reagents
OH Higher than reagent blank
OL Lower than reagent blank
PD The sample has been diluted
U The responsiveness exceeds the upper limit of the calibration
L The responsiveness is below the lower limit of the calibration
RLU Upper limit of the reagent’s linear range
RLL Lower limit of the reagent’s linear range
RE Incorrect setting of the reference range for test results
RLE Incorrect setting of the upper or lower limits of the reagent’s linear range
Ex Abnormal test or the test has been interrupted
LE Insufficient light intensity
CE Incorrect calculation of the concentration
↓ Below the reference range
↑ Above the reference value
164

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SERVICE MANUAL

GBA-1000 Biochemistry Analyzer

Goldsite Diagnostics Inc.

when an abnormality occurs in the instrument.

 Please take normal protective measures when handling instrument

failures and maintaining instrument functions.

 Untrained personnel must maintain and repair the instrument under

the guidance of qualified personnel.

1.1. Environmental requirements................................................................................................. 1

1.2. Power requirements ............................................................................................................. 1

1.3. Temperature and humidity requirements.............................................................................. 1

1.4. Water supply and drainage requirements ............................................................................ 2

1.5. Installation process ............................................................................................................... 2

2. Chapter II Analyser Overview ............................................................................................................. 4

2.1. Analyser test principle .......................................................................................................... 4

2.2. Analyser overview ................................................................................................................ 5

3. Chapter III Components and functions ............................................................................................... 7

3.1. Components ......................................................................................................................... 7

3.1.1. Reaction disk drive shaft assembly............................................................................... 7

3.1.2. Reaction plate ............................................................................................................... 8

3.1.3. Optical module .............................................................................................................. 9

3.1.4. Reagent disk cooling module ........................................................................................ 9

3.1.5. Probe outer washing module ...................................................................................... 10

3.1.6. Pump ........................................................................................................................... 10

3.1.7. Touch screen ................................................................................................................11

3.1.8. Front cover .................................................................................................................. 12

3.1.9. Sample tray holder ...................................................................................................... 12

3.1.10. YZ axis movement module.......................................................................................... 13

3.1.11. Driver protect shell ...................................................................................................... 13

3.1.12. Plunger pump module ................................................................................................. 14

3.2. Program content: ................................................................................................................ 15

3.2.2. Mainboard Power Supply Voltage Test: ...................................................................... 16

3.2.3. Reaction disk position calibration................................................................................ 16

3.2.4. Sample probe-washing well position calibration ......................................................... 18

3.2.5. Sample probe-reaction cuvette position calibration .................................................... 18

3.2.6. Sample probe-reagent disk position calibration .......................................................... 20

3.2.7. Sample probe-standard cup position calibration......................................................... 21

3.2.8. Sample probe-Micro cup position calibration .............................................................. 22

3.2.9. Sample probe-BCT (Blood collection tube) position calibration. ................................ 23

3.2.10. Sample probe-Bubble remove position calibration. .................................................... 24

3.2.11. Light position adjustment ............................................................................................ 24

3.2.12. Stirring calibration ........................................................................................................ 27

3.2.13. Sample tube detection calibration ............................................................................... 28

3.2.14. Reagent disk cover detection ...................................................................................... 29

3.2.15. Sample probe anti-collision function detection ........................................................... 30

3.2.16. Reaction disk control button function detection .......................................................... 30

3.2.17. Inlet and outlet components detection ........................................................................ 31

3.2.18. Serial port detection .................................................................................................... 31

3.2.19. USB port detection ...................................................................................................... 31

3.2.20. Net port detection ........................................................................................................ 31

3.2.22. Halogen fan detection ................................................................................................. 32

3.2.24. Probe inner waterflow detection.................................................................................. 33

3.2.25. Printer detection .......................................................................................................... 33

3.2.26. Time test ...................................................................................................................... 33

4. Chapter IV Replacement of common parts....................................................................................... 34

4.1. Disassembly and precautions ............................................................................................ 34

4.2. Instrument pipeline installation requirements ..................................................................... 35

4.3. Replace modules ................................................................................................................ 36

4.3.1. Replace the pump unit ................................................................................................ 36