Sulfamethaxazole, Salbu + Ipra
Sulfamethaxazole, Salbu + Ipra
Sulfamethaxazole, Salbu + Ipra
Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects Nursing Responsibilities
Generic Name: Pharmacologic Ipratropium bromide is an The combination of Hypersensitivity to CNS: dizziness,blurred Before
Salbutamol + Class: anticholinergic albuterol and ipratropium salbutamol, ipratropium vision 1. Check the doctor’s order
Ipratropium Anticholinergic (parasympatholytic) agent which is used to prevent or fenoterol, atropine or 2. Assess allergy to the drug
appears to inhibit vagally- wheezing, difficulty its derivatives. GI: nausea, drymouth 3. Caution patient of the different
Trade/Brand Name: mediated reflexes by breathing, chest Hypertrophic obstructive side effects
Combivent, DuoNeb, Therapeutic antagonizing the action of tightness, and coughing cardiomyopathy, Respi: 4. Obtain baseline vital signs
Breva Class: acetylcholine, the transmitter in people with chronic tachyarrhythmia. dyspnea,bronchospasms 5. Prepare drugs properly at the
Bronchodilator agent released at the obstructive pulmonary ,horseness right dosage.
Patients’ Dose: neuromuscular junctions in the disease (COPD; a group
Salbutamol + lung. Anticholinergics prevent of diseases that affect the CV: palpitations,chest
Ipratropium neb q 6H the increases in intracellular lungs and airways) such pain During
concentration of Ca++ which is as chronic bronchitis 1. Verify patient’s identity
Route: caused by interaction of (swelling of the air Interaction 2. Explain to patient the purpose of
Inhalation acetylcholine with the passages that lead to the DRUGS medication
muscarinic receptors on lungs) and emphysema Increased adverse effects 3. To inhale the solution as a
Form: bronchial smooth muscle. (damage to the air sacs in with corticosteroids, nebulizer, teach these steps to the
Nebulizer solution the lungs). Albuterol and xanthine derivatives, patient:
Salbutamol relaxes bronchial, ipratropium combination diuretics. - Remove one vial of medication
Maximum dose: uterine, and vascular smooth is used by people whose from the foil pouch. Put the rest of
<6 times/ 24 hours muscle by stimulating beta 2 symptoms have not been the vials back into the pouch until
receptors. controlled by a single you are ready to use them.
Minimum dose: inhaled medication. - Twist off the top of the vial and
4 times/ 24 hours squeeze all of the liquid into the
Pharmacokinetics reservoir of the nebulizer.
Availability: Absorption: Ipratropium: Patient’s Indication: - Connect the nebulizer reservoir to
Inhalation Solution (vial) Rapidly absorbed after Prevent the mouthpiece or face mask.
inhalation. Bioavailability: difficulty in - Connect the nebulizer reservoir to
Content: <10%; Salbutamol: Rapidly and breathing, chest the compressor.
Albuterol Sulfate 2.5 mg completely absorbed after tightness. And - Put the mouthpiece in your mouth
in 3mL inhalation. Time to peak plasma coughing (PTB or put on the face mask. Sit in a
Ipratropium Bromide 0.5 concentration: Within 3 hours. also affects the comfortable, upright position and
mg in 3mL Distribution: Ipratropium: lungs and its turn on the compressor.
Plasma protein binding: <20%. airways) - Breathe in calmly, deeply, and
Metabolism: Ipratropium: evenly through your mouth for
Partially metabolised to inactive about 5 to 15 minutes until mist
ester hydrolysis products; stops forming in the nebulizer
Salbutamol: Undergoes first-pass chamber.
metabolism in the liver and
possibly in the gut wall.
Metabolised to inactive sulfate After
conjugate. 1. Monitor vital signs noting
Excretion: Ipratropium: Via hypotension and an irregular or
urine and faeces. Terminal abnormal pulse.
elimination half-life: 1.6 hours. 2. Monitor for adverse effects.
Salbutamol: Via urine (as 3. Maintain a quiet, comfortable
metabolites and unchanged environment to minimize anxiety.
drug); faeces (small amounts). 4. Document correctly and
Elimination half-life: 3-7 hours. accordingly.
Half life:
- Salbutamol: 4 hr; Ipratropium:
2 hr
Peak:
- Salbutamol: 2-3 hr;
Ipratropium: 1-2 hr
Onset:
- Salbutamol: 15-30 minutes;
Ipratropium: 5-15 minutes
Duration
-- Salbutamol: 4-8 hr;
Ipratropium: 3-6 hr
Vallerand, A., Vallerand, A., Sanoski, C., & Vallerand, A., Sanoski, Vallerand, A., Sanoski, Vallerand, A., Sanoski, Vallerand, A., Sanoski, C., &
Sanoski, C., & Deglin, J. (2017). Drug Guide C., & Deglin, J. (2017). C., & Deglin, J. (2017). C., & Deglin, J. (2017). Deglin, J. (2017). Drug Guide for
Deglin, J. (2017). for Nurses. 15th Ed. FA Davis Drug Guide for Nurses. Drug Guide for Nurses. Drug Guide for Nurses. Nurses. 15th Ed. FA Davis
Drug Guide for Company: Philadelphia 15th Ed. FA Davis 15th Ed. FA Davis 15th Ed. FA Davis Company: Philadelphia
Vallerand, A., Sanoski, Nurses. 15th Ed. Company: Philadelphia Company: Philadelphia Company: Philadelphia
C., & Deglin, J. (2017). FA Davis Schull, P. D. (2013). McGraw- Schull, P. D. (2013). McGraw-Hill
Drug Guide for Nurses. Company: Hill nurses drug handbook. New Schull, P. D. (2013). Schull, P. D. (2013). Schull, P. D. (2013). nurses drug handbook. New York:
15th Ed. FA Davis Philadelphia York: McGraw-Hill Medical. McGraw-Hill nurses drug McGraw-Hill nurses drug McGraw-Hill nurses McGraw-Hill Medical.
Company: Philadelphia handbook. New York: handbook. New York: drug handbook. New
Schull, P. D. JONES & BARTLETT McGraw-Hill Medical. McGraw-Hill Medical. York: McGraw-Hill JONES & BARTLETT
Schull, P. D. (2013). (2013). McGraw- LEARNING. (2018). Nurses Medical. LEARNING. (2018). Nurses Drug
McGraw-Hill nurses drug Hill nurses drug Drug Handbook. SUDBURY. JONES & BARTLETT JONES & BARTLETT Handbook. SUDBURY.
handbook. New York: handbook. New LEARNING. (2018). LEARNING. (2018). JONES & BARTLETT
McGraw-Hill Medical. York: McGraw- Nurses Drug Handbook. Nurses Drug Handbook. LEARNING. (2018).
Hill Medical. SUDBURY. SUDBURY. Nurses Drug Handbook.
JONES & BARTLETT SUDBURY.
LEARNING. (2018). JONES &
Nurses Drug Handbook. BARTLETT
SUDBURY. LEARNING.
(2018). Nurses
Drug Handbook.
SUDBURY.