MCN Midterm 1
MCN Midterm 1
implantation
Presumptive – felt by the mother (subjective) least Embryo From implantation to
indicative of pregnancy. 5-8 weeks
Amenorrhea, nausea and vomiting, frequent Fetus From 5 weeks until
urination, fatigue (baby uses the sugar of the term
mother) Conceptus Developing embryo or
Chloasma gravidarum - darkening of the
detus and placental
structures throughout
face
pregnancy
Linea nigra – dark line on the abdomen
Striae gravidarum
5 PRODUCTS OF CONCEPTION
Probable – felt by the examiner or the nurse.
1. Fetus,
Abdominal enlargement
2. Placenta/pancake
Hegar sign – softening of the lower portion
3. Umbillical cord/funis
of the uterus
4. Amiotic fluid
Chadwich sign – darkening of vagina
5. Amiotic sac
Ballotment – baby is bouncing occurs in 4th
B. Implantation
month
Zygote migrates towards the body of uterus
Goodle sign – softening of cervix
which taks 3 or 4 days
Braxtonhic sign – painless palpable
Cleavage or mitotic cell division begins: 24
contraction
hours
Pregnancy test (male positive in pregnancy
Blastomeres
test indicates testicular cancer)
Time zygote reaches body of uterus it
Positive
consists of 16-50 cells
ultrasound, fetal hearbeat, fetal
In initial cell division, 2 blastomeres until
movement/quickening (felt by the examiner)
after 3-4 days
Morula
Antepartum period – woman know that she is
Blastomeres that will arrange in a ball-like
pregnant/nalaman. Longest period (9 months)
structure
Intrapartum – labor, delivery, removal of placenta
Travels to uterus and stays for 3-4 days
Postpartum – 6 weeks following pregnancy
Blastocyst
Multiplication of morula forming solid
Trimester
clump of cells
1st trimester – first 3 months
Trophoblast (fingerlike projections)
2nd trimester (4-6 months)
Outer ring replacing zona pellucida
3rd trimester (7-9 mmonths)
EMBRYONIC AND FETAL STRUCTURES
After implantation, endometrium is termed
A. Fertilization
DECIDUA, which has 3 portions:
(conception/impregnation/fecundation)
1. Decidua basalis – lies directly under
Union of ovum and spermatozoa
embryo
Occurs in outer third of fallopian tube, the
2. Decidua capsularis – portion stretches and
ampullar region
encapsulate the surface of trphoblast
Critical time span occurs about 72 hours
3. Decidua vera – remaining portion of uterine
After ovulation, the ovum is extruded from
lining
graafian follicle, surrounded by a ring of
Chorionic Villi - finger like projections
mucopolysaccharide fluid (zona pellucida)
responsible for secretion of pregnancy hormones
and circle of cells (corona radiata)
human chorionic gonadotrophin (HCG) and human
Capacitation
placental lactogen (HPL), estrogen, progesterone
Ejection of DNA of sperm to ovum
*At the time of implantation, there are 3 important
Final process for fertilization
changes in the embryo that occurs simultaneously –
Changes in plasma membrane of sperm head
formation of membranes
Factors affecting fertilization
1. Chorionic membrane – first membrane to
1. Maturity of sperm and ovum
be formed. Protects and support embryo
2. Ability of sperm to reach ovum
during growth and development
3. Ability of sperm to penetrate zona pellucida
2. Amniotic membrane – thin protective
Terms used to denote fetal growth membrane containing amniotic fluid. The
Ovum From ovulation to
fertilization
space between membrane and embryo is Protected by whaton’s jelly – transparent
amniotic cavity. gelatinous white substance which
Amnion – produces amniotic fluid. Usually 800 – prevents pressure on veins and arteries
1200cc average amount of amniotic fluid Veins and arteries
Polyhydramnios – more than 2,000 mL 21 inches in length
Oligohydramnios – less than 300 Ml 2 cm in thickness
2 arteries (carrying blood from fetus back to
Functions of Aminiotic fluid placental vili)
1. Shields against [ressure or blow to mother’s 1 vein (carrying blood from placental vili to
abdomen fetus)
2. Protects fetus against changes in Functions:
environment – temperature Transport O2
3. Muscular development allowing fetus to Nutrients to fetus from placenta
move freely Return waste products from fetus to placenta
4. Protects umbilical cord from pressure, Organogenesis – first 3 months when organs begin
protecting fetal oxygen supply to grow
C. Placenta/pancake ORIGIN OF ORGAN SYSTEMS
Provides nutrition and blood suppy and
oxygen supply. FETAL GROWTH AND DEVELOPMENT
15-20 cm in diameter at the beginning of First lunar month
pregnancy Germ layers differentiate by the 2nd week
2-3 cm in thickness; weighs 500 grams at 1. Endoderm - gives rise to lining of GIT,
term Respiratory Tract, tonsils, thyroid (for basal
Covers half surface area of internal uterus metabolism, parathyroid (for calcium metabolism),
Mature placenta has 16-30 separate thymus gland (for development of immunity),
segments called cotyledons bladder and urethra
2 Portions: 2. Mesoderm - forms into the supporting structures
Maternal portion – formed by deciduas of the body (connective tissues cartilages. muscles
basalis and its circulation. Surface is red and and tendons); heart circulatory system, blood cells,
flesh like-presnce of cotyledon Looks rough, reproductive system, kidneys and ureters.
uneven, and dirty (duncan) 3. Ectoderm - responsible for the formation of the
Fetal portion – made up of chorionic vili nervous svsten skin, hair and nails and the mucous
and its circulation membrane of the anus ands mouth
Give shiny and grayish apperance (shaltz)
Functions: Stages of Human Prenatal Development
1 Serves as fetal lungs, kidneys and a. First 12 - 14 days = zygote
gastrointestinal tract b. From 15th day up to 8th week = embryo
2 Endocrine functions: C. From 8th week up to the time of birth = fetus
HCG – first hormone produced
Estrogen – contributes to mother’s DEVELOPMENT OF ORGAN SYSTEMS
ammmary gland development in A. Cardiovascular System
preparation for lactation • 6th or 7th week- septum divides the heart into
Progesterone – maintain chambers
endometrian lining produced by • 10th-12th week- heartbeat may be heard with a
placenta staring 8 or 12th week doppler o 11th week - ECG may be recorded on
pregnancy. fetus
Human placental lactogen – growth • 16th day of life- single heart tubes form o 24th day
promoting and lactogenic (milk- of life- heart beats
producing) properties by 6 weeks • 28th week - Sympathetic Nervous System matures
Protection againsta invading heart rate
microorganisms and chemical B. Respiratory System
substance • 3rd week - Intrauterine life:
D. Umbilical cord respiratory and digestive tracts
Formed from amnion and chorion exists as a single tube
Provides circulatory pathway that 4th week - septum begins to divide the
connects embryo to chorionic vili of esophagus from the trachea. lung buds appear
placenta on the trachea
• 7th week - diaphragm does not completely divide • Vernix caseosa - important for lubrication and for
the thoracic cavity from the abdomen keeping the skin from macerating in utero.
Respiratory Milestone J. Immune System
28th week alveoli and capillaries begin to form • IgG - increases phagocytosis: provide immune
SURFACTANT -phospholipid substance formed protection to the fetus and newborn.
and excreted at about 24th week of pregnancy
COMPONENTS: MILESTONES OF FETAL GROWTH AND
• 35th week - production of lecithin o 2: 1 (Lecithin: DEVELOPMENT
Sphingomyelin) End of 4 Gestation Weeks
• Respiratory Distress- lack of surfactant • Length - 0.75 cm to 1 cm
C. Nervous System - Weight - 400 mg
3rd Week - a neural plate is apparent forming th • The spinal cord is formed and fused at midpoint
CNS (brain and spinal cord) Trophoblasts embed in decidua
8th week = brain waves can be detected by the Chorionic villi form
EEG • Foundation for nervous system, GUT, skin.
• All parts of the brain (cerebellum, cerebrum, bones and lungs are
medulla oblongata and pons) form in utero formed
• 24 weeks = ear is capable of responding to sound: • The rudimentary heart appears as a prominent
eyes exhibit pupillary reaction bulge on the anterior surface
• Meningocele or Anencephaly • Back is bent so the head almost touches the tip of
D. Endocrine System the tail
o Thyroid and parathyroid glands - play vital roles • Arms and legs are budlike structures
in • Rudimentary eyes, ears and nose appear
metabolic function and calcium balance
• Fetal Pancreas - produces insulin End of 8 Gestation Weeks
o Fetal Pancreas - produces insulin • Length - 2.5 cm
E. Digestive System o 4th week- digestive tract is • Weight - 20 g
separated from th respiratory tract • Organogenesis is complete
o 10 week - abdominal cavity has grown large • The heart, with a septum and valves, is beating
enough to accommodate all intestinal mass o 6th • Facial feature are definitely discernible
week- meconium forms in the intestine o GIT is • Primitive tail is regressing
sterile before birth - becausts Vit. K is synthesized • Head is disproportionately large, owing to brain
by the action of bacteria in the intestines. development
• Sucking and swallowing reflexes are not mature o • Abdomen appears lage due to rapid growth of fetal
Liver is active, functioning as a filter between the intestine
incoming blood and fetal • External genitalia is present, but sex is not
o Fetal stores such as iron and glycogen. o It is still distinguishable by simple observation
immature after birth, possibly
hypoglycemia and hyperbilirubinemia End of 12 Gestation Weeks
(2 lead to serious • Length - 7 to 8 cm
problems 24 hours after birth) • Weight - 45 grams.
• Nail beds are forming on fingers and toes
Meconium – first stool of the newborn • Spontaneous movements are possible, but not felt
Vitamin k .1 is given to newborn for clotting by the mother
purposes preventing hemoraditc disease of newborn • Bone ossification centers are forming
• Tooth buds are present
F. Musculoskeletal System • Sex is distinguishable by outward appearance
(° 11° week - fetus can be seen moving • Placenta is complete
(quickening) but cannot be felt by the mother • Heart is audible by a Doppler
• 12* week- ossification of bone tissue begins • Kidney secretion has begun
G. Reproductive System
• 6th week - gonads (testes and ovaries) form, testes End of 16 Gestation Weeks
are • Length - 10 to 17 cm
H. Urinary System • Weight 55 - 120 grams
• 44 week - kidneys are present in the abdominal • Fetal heart sounds are audible by an ordinary
cavity stethoscope
1. Integumentary System • Sex can be determined by Ultrasound
• Lanugo - soft downy hairs • Lanugo is well formed
• Liver and pancreas are functioning •Length - 42 to 48 cm
• Nasal septum and palate close • Weight - 1800 to 2700 grams
• Fetus actively swallows amniotic fluid • Body stores of glycogen, iron, carbohydrate, and
• Urine is present in amniotic fluid calcium are augmented
• Additional amount of subcutaneous fats are
End of 20 Gestation Weeks deposited
• Length - 25 cm • Amount of lanugo begins to diminish
• Weight 223 grams • Amniotic fluids decreases
• Spontaneous fetal movements are felt by the • Sole of foot has 1 or 2 crisscross creases
mother
* Antibody production is possible End of 40 Gestation Weeks
Hair forms, extending to include eyebrows and hair • Length - 48 to 52 cm
on • Weight - 3000 grams
the head • Fetus kicks actively, hard enough to cause the
• Meconium is present in the upper intestine mother considerable discomfort
• Brown fat, a special fat that will aid in temperature • Creases on soles of feet cover at least 2/3 of the
regulation at birth, begins to form behind the surface
kidneys, sternum, and posterior back • Vernix caseosa fully formed
• Heart sounds are perceptible by auscultation • Fingernails extend over the fingertips
• Vernix caseosa appears
• Definite sleeping and activity patterns are THE DIAGNOSIS OF PREGNANCY
distinguishable (the fetus has devlop bio rhythms
that will guide sleep/wake patterns throughout life) Presumptive signs of pregnancy- are those tha are
least indicative of pregnancy
End of 24 Gestation Weeks • Amenorrhea
• Length - 28 to 36 cm • Nausea and Vomiting (morning sickness)
• Weight- 550 grams • Breast Changes
• Skin appears wrinkled • Frequent urination
• Meconium is present as far as the rectum • Quickening
• Active production of lung surfactant begins • Fatigue
• Eyebrow and fingernails are well defined • Changes in abdominal shape
• Pupils are capable of reacting to light • Linea nigra
• Hearing can be demonstrated by response to • Leukorrhea
sudden sound • Striae gravidarum
PELVIC EXAMINATION
• External genitalia (signs of inflammation,
irritation or infection)
• Internal genitalia
BARTOLOMEW'S RULE
GROWTH OF THE FUNDIC HEIGHT
• 12 weeks - level of symphysis pubis
•16 weeks - halfway between symphysis pubis and • (Determines small parts and back of fetus along
umbilicus the sides maternal abdomen)
• 20 weeks - level of umbilicus a. Exmainer faces the woman's head
• 24 weeks - two finger above umbilicus b. Palpate the sides of the abdomen to detect
• 28-30 weeks - midway between umbilicus and location of the fetal back and fetal small part
xiphoid process c. Palpate fetus between two hands
• 36 weeks - at the level of xiphoid process - Back: hard, smooth, resistant plane
• 40 weeks - two fingerbreadths below umbilicus, - Small parts: irregular, nodular with bony
drops at 34 weeks level because of LIGHTENING prominence