JAVIEER, Marivic O.

BSN 3-1
DRUG STUDY (DM)
NAME OF DRUG DOSAGE ACTION INDICATION CONTRAINDICATION SIDE EFFECT NSG. RESPONSIBILITIES
GENERIC NAME: PO Initiate Acarbose is an Alpha- Inflammatory bowel Sleepiness, • Lab tests:
Acarbose with 25 mg oral alpha- glucosidase disease, colon ulcers, weakness, dizziness, Periodically monitor blood glucose,
qd. to TID glucosidase inhibitors (AGIs; partial bowel headache, vertigo HbA1C liver, enzymes, Hct and Hgb.
BRAND NAME: with meals inhibitor. It acarbose, obstruction, (may be due to poor • Treat hypoglycemia with dextrose;
Precose inhibits or delays miglitol, predisposition for diabetic control). not with sucrose (table sugar).
the absorption of voglibose) are obstruction; patients Endocrine:
CLASSIFICATION: sugars from the widely used in <18 y; lactation. Hypoglycemia • Note: Acarbose prevents the
Hormone and intestinal tract. the treatment of (especially in breakdown of table sugar. Have a
Synthetic The inhibitory patients with combination with source of dextrose, such as dextrose
Substitutes, Alpha- effect of type 2 diabetes. sulfonylureas and paste, available to treat low blood
Glucosidase acarbose varies AGIs delay the insulin). GI: Diarrhea, sugar
Inhibitors according to absorption of flatulence, abdominal • Monitor closely blood glucose
which enzymes carbohydrates distention, especially
are involved; from the small borborygmi, following dosage changes.
from most to intestine and increased liver • Report abdominal distress; dietary
least inhibited thus have a function tests. adjustment or dosage reduction may
are lowering effect Hematologic: Anemia be warranted.
glucoamylase, on postprandial (especially iron • Monitor weight and report
sucrase, blood glucose deficiency). Skin: significant changes.
maltase, and and insulin Erythema, • Do not breast feed while taking this
isomaltose. levels. exanthema, urticaria. drug.
Lactase is not
affected by
acarbose.
NAME OF DOSAGE ACTION INDICATION CONTRAINDICATION SIDE EFFECT NSG. RESPONSIBILITIES
DRUG
Generic Diamicron Diamicron Gliclazide is This medication must Medicines and their possible side Patients who are NPO may need to
Name: MR is for use MR is used a blood not be used in the effects can affect individual have their dose held to avoid
Gliclazide in adults only. in the glucose- following cases people indifferent ways. The hypoglycemia.
Dose may treatment lowering -if you are allergic to following are some of the side
Brand Name: vary from 30- of type II agent. Non- gliclazide-if you have effects that are known to be
Diamicron 120mg, taken (non-insulin insulin diabetes requiring associated with this medicine.
once daily dependent) dependent treatment with insulin- Just because aside effect is
Classification: Should be diabetes diabetes in case of diabetes stated here does not mean that
Oral Anti- taken with that cannot (NIDDM) is complicated by all people using this medicine will
Diabetic food, be due to a ketosis and acidosis, experience that or any side
agent preferably at controlled decreased diabetic precoma-if effect. Disturbances of the gut
breakfast with diet sensitivity of you suffer from severe such as diarrhea, constipation,
time Tablets and the body liver or kidney indigestion, nausea, vomiting or
are modified exercise. cells to disease. -in case of abdominal pain.
release, insulin, but porphyria:
therefore the pancreas accumulation of
should not be still can pigments (porphyria)
broken or produce in the body-if you are
chewed insulin. presently taking a
Always titrate Gliclazide treatment with
dose stimulates miconazole (see
according to the islet cells interactions with other
individual of the medications)-if you
patient pancreas to are breast-feeding
requirements, secrete
insteps of insulin, and
30mg also
Daily dose increases
should not their
exceed sensitivity to
 120mg their normal
Diamicron stimulus,
MR can glucose.
replace other These
Gliclazide effects
80mg tablets, restore the
one for one (first phase)
insulin
secretion
that has
become
diminished in
NIDDM
patients.
Gliclazide
also has
effects
outside the
pancreas,
where it
improves
insulin-
stimulated
usage of
glucose.

NAME OF DRUG DOSAGE ACTION INDICATION CONTRAINDICATION SIDE EFFECT NSG. RESPONSIBILITIES
Generic Name:

Brand Name:

Classification: