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Proteins

Proteins play essential roles in the body and are synthesized in cells. They have complex structures and functions that include transporting substances, catalyzing reactions, and providing structure. The document discusses 11 types of plasma proteins including prealbumin, albumin, and various globulins. Each protein type has distinct characteristics such as structure, function, concentration levels, and clinical significance in health and various disease states.
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0% found this document useful (0 votes)
25 views5 pages

Proteins

Proteins play essential roles in the body and are synthesized in cells. They have complex structures and functions that include transporting substances, catalyzing reactions, and providing structure. The document discusses 11 types of plasma proteins including prealbumin, albumin, and various globulins. Each protein type has distinct characteristics such as structure, function, concentration levels, and clinical significance in health and various disease states.
Copyright
© © All Rights Reserved
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Download as DOCX, PDF, TXT or read online on Scribd
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1. Proteins: 11.

What is the balance between anabolism and


 Role in the body? catabolism?
 Greek word and meaning?  Include its types
 Synthesized where?
 Size? 12. What are the plasma proteins?
 What charges?
 What acid and base? 13. Prealbumin
 Are they soluble?  Migrates where?
 Are they antigens?  Total MW:
 How much do they provide total daily  Each monomer can do what?
body energy requirement?  What is its significant role?
 How much is their cell’s dry weight?  Has what conformation?
 Is rich in what and used for?
2. Structures of Proteins:  Is the source for what?
 Importance?  Life span in circulation?
 Role or responsibility?  Sensitive to?
 How it functions? What happens if  Where is it produced?
there are changes?  Is used to detect for?
 Is there maintenance?  How is it useful in CSF specimen?
 True prealbumin is best quantified by?
3. Functions of proteins
 Give the function and its examples: 14. Increased and Decreased of Prealbumin

4. Classification of Proteins based on their 15. Reference value for Prealbumin


Functions:
 Explain the role, location, what it 16. Albumin
affects, and examples.  It is present where?
 Explain the structures and sequences.
5. Most common sample is? Explain why?  It is synthesized where and at what
rate?
6. What gives info about patient’s general state  Life span is?
regarding nutrition or severe organ disease?  It is responsible for?
 Leaves the bloodstream at what rate?
7. Explain Protein Electrophoresis
17. What is a negative phase reactant? Explain
8. What provides display of all the components in further.
concentration in the electrophoresis down to
about 1g/L? 18. Reference value for Albumin

9. What are the metabolic states of Amino acids? 19. Primary functions of Albumin
 Differentiate each and give examples
for each 20. Albumin also serves as what?
10. Classifications of Proteins according to their
Structure: 21. Up to 8% of Albumin circulating in normal
 Differentiate each, give the forms or person becomes?
types of each.
 Include the composition of each and 22. Albumin is an indicator for?
examples for each type or form
23. Is Albumin sensitive and a prognostic marker?
36. Diagnostic significance second type of Globulin
24. Increased and Decreased of Albumin?
37. Third type of globulin
25. Lowest plasma Albumin levels cause? What  Is what kind of protein?
progression?  Synthesized by?
 Contains what high of percentage?
26. Nephrotic Syndrome:  Has what Ph?
 Marked by?  Has what great affinity?
 Due to?  Function is?
 Useful in?
27. Globulin  Concentrations of this is used for?
 Is what?  Method or test used?
 Measured by?  Explain all diagrams
 Elevated concentrations cause?
 Formula for measurement 38. Increased and Decreased of this third type of
Globulin
28. Reference value for Globulin
39. Reference value for third type of Globulin
29. What are the types of globulin?
40. Fourth type of Globulin
30. First type of Globulin  Is what kind of protein?
 Is what kind of protein?  Function is?
 Composed of?  Migrates where?
 Has the capacity to?  Binds to?
 Main functions is?  Major form of what?
 Mutation of what gene can cause  Associated with?
deficiency of this globulin?  Mutations are:
 Abnormal for of this globulin causes
what? 41. Increased and Decreased of this fourth type of
 PHENOTYPES are: Globulin
31. Increased and Decreased of this first type of
Globulin 42. Reference value for fourth type of Globulin

32. Reference Value for first type of Globulin 43. Fifth type of Globulin
 Is what and synthesized where?
33. Second type of Globulin  Functions are:
 Is what kind of protein?  Helps with?
 Synthesized where?  What complex? Carries where? Binds
 What serum is used? Why? and migrates to?
 Peaks during? 44. Reference value for fourth type of globulin
 Detectable where?
 What function for adults? 45. Sixth type of globulin
 What specimen is used?  Also known as?
 Method used?  Synthesized where?
 Also uses as what marker?  A major what?
34. Increased and Decreased of this second type of  Function is?
Globulin  Migrates and binds to?
35. Reference value for second type of globulin?  Important for what?
 What are the three major 55. Increased and decreased of this ninth type of
electrophoretic vairants? Globulin
 Method used?
46. Increased and Decreased of this sixth type of 56. Reference value for the ninth type of globulin
Globulin
57. Tenth type of globulin
47. Reference value for sixth type of globulin  Is what kind of component?
 Found where?
48. Seventh type of globulin  Needed for what?
 Is what kind of protein?  Filtered where?
 Synthesized where?  Appears in?
 When hemoglobin binding capacity of  Has a tendency to?
hemoglobin exceed what happens?  Method used is?
 What complex? Binds to? Evaluates
degree of what? 58. Increased and decreased of this tenth type of
 What is the similarity of this protein Globulin
during intravascular hemolysis of HDR
and HDN? 59. Reference value for the tenth type of globulin
 Useful measurement for?
 Used to evaluate what? 60. Eleventh type of globulin
 Plasma level is decreased or increased?  Is what kind of component?
 Phenotype of this globulin?  Consists of how many amino acids?
 What are the three phenotypes?  Is what kind of protein?
 Methods used are?  Synthesized by?
 This globulin and other blood  Variant in? Sample is? Detection of?
parameters. Explain.  CSF contains? Plasma contains?
49. Increased and Decreased of this seventh type of  Transports what?
Globulin  Used to determine what cause?
 Different deficiencies explain.
50. Reference value for the seventh type of  ____-deficient of this globulin
globulin  Determines what effect?
 Chronic saturation of this globulin
51. Eighth type of globulin occurs in?
 Is what kind of protein?  What is atransferrinemia?
 Synthesized where?  What is total iron binding capacity?
 Imparts what color to protein/
 A marker for? Explain why. 61. Increased and decreased of this eleventh type
 Methods used: of Globulin
52. Increased and decreased of this eighth type of
Globulin 62. Reference value for the eleventh type of
53. Reference value for the eighth type of globulin globulin both male and female

54. Ninth type of globulin


 Is what kind of protein?
 Found where?
 Important for maintaining what?
 Spectrum for this is? 63. Twelfth type of globulin
 Methods used are:  Is what kind of protein?
 Synthesized where?
 What abundant globulin is found in  Binds to?
plasma and lymph? Found in mucous  What kind of molecule?
secretion? Appears in response to  What kind of protein?
antigen stimulation? Is present mostly  Highly sensitive _______; appears in?
on the surface B cells? Associated with  Marker for? (2)
allergic and anaphylactic reactions?  Used as what test?
 Methods used are:  High-sensitivity of this globulin: is what
protein and commonly used to
64. Increased and decreased of this twelfth type of determine what? Increase of this
Globulin predict?
65. Reference value for the twelfth type of globulin
74. Increased and decreased of this sixteenth type
66. Thirteenth type of globulin of Globulin
 Binds with?
 Transports what? 75. Reference value for the sixteenth type of
globulin
67. Fourteenth type of globulin
 Is what kind of protein? 76. First miscellaneous protein
 Synthesized where?  What kind of protein?
 Most abundant in?  Found in?
 Appears as a distinct band between?  MW is:
 Marker for?  Filtered by?
 What is congenital afribrinogenemia?  Diagnostic significance:
 What is Dysfibrinogenemia?  Screening test used?
 A potential?
68. Increased and decreased of this fourteenth type  Methods used:
of Globulin  Increased:
 AMI value is:
69. Reference value for the fourteenth type of 77. Second miscellaneous protein
globulin  What kind of protein?
 For diagnosis of?
70. Fifteenth type of globulin  Regulators of?
 One of what mechanism?  ____are nearly absent for normal
 Participates in what reaction? serum
 Most form in serum is?  _____present in both cardiac and
 Marker to assess what? skeletal muscles
 Methods are:  ___binds to calcium ions that regulates
muscle contractions
71. Increased and decreased of this fifteenth type  Normal value is:
of Globulin  Diagnostic significance:
 Types are: (differentiate each)
72. Reference value for the fifteenth type of 78. Fourth miscellaneous protein
globulin  Are what family?
 Types are: (differentiate each)
79.
73. Sixteenth type of globulin
 A member of?
 Found in patients that had? Also found
in?

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