English BK-200mini - Service Manual - 2020.02.10 - WZH
English BK-200mini - Service Manual - 2020.02.10 - WZH
English BK-200mini - Service Manual - 2020.02.10 - WZH
BK-200mini
Service Manual
Intellectual property
Description -1
Description
Statement
Our company makes no warranties of any kind with respect to this manual,
including, but not limited to, warranties of implied merchantability and fitness for
a particular purpose.
Our company is responsible for the safety, reliability and performance of the
product when all of the following requirements are met:
Assembly operations, expansion, re-adjustment, improvement, repair and
replacement of parts are performed by professionals recognized by our
company.
All repairs involving replacement parts and supporting accessories and
consumables are original (original) or approved by our company.
The relevant electrical equipment complies with national standards and the
requirements of this user manual.
Product operation is carried out in accordance with this user manual.
Description -2
Description
Revision statement
This document applies to the latest and higher version of the software listed. A
new version of the document will be released if subsequent software releases
result in changes to the information in this document.
Initial version: V1.0, Mar, 2019
Software version: SHY-200-KZ-V1.0.0
The purpose of creating this document is to improve the integrity and practicality
of the service manual.
Description -3
Description
Product Categories
The classification criteria are described below:
Overvoltage category: Overvoltage category (Ⅱ)
Pollution level: Pollution level(Ⅱ)
Noise level: 75dB(A distance of more than 1m from the analyzer)
Installation environmental conditions:
a) Indoor use.
b) Altitude does not exceed 2000m.
c) Temperature range 15℃~30℃.
d) The maximum relative humidity is 85% when the temperature is lower than 30℃.
e) Power supply voltage fluctuation is not more than ±10% of the nominal voltage.
f) Typical transient overvoltage present on the main supply.
g) Applicable rated pollution level.
h) No abnormal noise equipment nearby.
i) The equipment complies with the emission and immunity requirements of IEC 61326-1. It
is forbidden to use the equipment beside strong radiation sources (such as unshielded RF
sources), otherwise it may interfere with the normal operation of the equipment.
Equipment category: Laboratory equipment.
Connection to the network power supply: Detachable power cord.
Operating conditions: Continuous.
Transportation and storage
Transportation
When the instrument is in the packaging status, take care to prevent rain and sun exposure
during transportation to prevent severe impact, heavy pressure and dumping.
Attention: If the instrument has been unpacked and needs to be moved, repack the instrument
before moving.
Storage
The packaged instrument should be stored at -10℃~40℃, relative humidity is not more than
85%, no corrosive gas and well ventilated environment.
Description-4
Description
Contact information
Company name: Biobase Biodustry (Shandong) Co., Ltd
Address: NO.51 South Gongye Road, Jinan, China
Service Email: [email protected]
Phone: +86-531-81219801/03
Zip code: 250000
Description -5
Catalogue
Catalogue
Statement.........................................................................................................................................................................2
After-sales service and contact information................................................................................................................... 5
Catalogue........................................................................................................................................................................ 1
Security Information....................................................................................................................................................... 1
1 System Overview.........................................................................................................................................................1
1.1Overview............................................................................................................................................................2
1.2Overall Structure........................................................................................................................................2
1.2.1Overall Appearance................................................................................................................................ 2
1.2.2Composition of Analyzer....................................................................................................................... 4
1.2.3 Structure of Movement..........................................................................................................................5
1.2.4 Function of Movement.......................................................................................................................... 6
2 System Performance and Test Progress...................................................................................................................... 1
2.1 Main Performance Parameters......................................................................................................................... 2
2.1.1 General Parameters................................................................................................................................2
2.1.2 Sample Parameters................................................................................................................................ 3
2.1.3 Reagent Parameters............................................................................................................................... 4
2.1.4 Reaction Parameters.............................................................................................................................. 4
2.1.5 Configuration.........................................................................................................................................5
2.2 Testing Process................................................................................................................................................. 5
2.2.1 The Start-up Process..............................................................................................................................5
2.2.2 Description of Test Process................................................................................................................... 5
2.2.3 Horizontal Axis Diagram of Test Points............................................................................................... 6
3 Installation Requirements and Steps........................................................................................................................... 1
3.1 Overview...........................................................................................................................................................2
3.2 Check before installation.................................................................................................................................. 2
3.2.1 Environment Check............................................................................................................................... 2
3.2.2 Configuration Check..............................................................................................................................2
3.3 Installation Requirements................................................................................................................................. 3
3.3.1 Installation space requirements............................................................................................................. 3
3.3.2 Power Supply and Noise....................................................................................................................... 3
3.3.3 Water Supply and Drainage...................................................................................................................4
3.4 Configuration Requirements of PC.................................................................................................................. 4
3.4.1 Processor Requirements........................................................................................................................ 4
3.4.2 Memory requirements........................................................................................................................... 4
3.5 Installation Steps...............................................................................................................................................4
3.5.1 Check Before Unpacking...................................................................................................................... 4
3.5.2 Unpacking..............................................................................................................................................5
3.5.3 The Connection of Instrument...............................................................................................................7
3.5.4 Connection of Analyzer.........................................................................................................................8
4 Introduction of Module................................................................................................................................................1
4.1 Housing Module............................................................................................................................................... 2
4.1.1 Module Function and Composition.......................................................................................................2
4.1.2 Maintenance of Top Cover....................................................................................................................2
4.1.3 Maintenance of Rear Panel....................................................................................................................3
4.1.4 Maintenance of Face Panel....................................................................................................................4
4.1.5 Maintenance of housing........................................................................................................................ 4
4.1.6 Maintenance of Gas Spring................................................................................................................... 6
4.2 Reaction Tray Module...................................................................................................................................... 7
4.2.1 Module Function and Composition.......................................................................................................7
4.2.2 FRU List................................................................................................................................................ 8
4.2.3 Maintenance of Temperature Sensor.....................................................................................................8
4.2.4 Maintenance of Reaction Tray Assembly............................................................................................. 9
4.2.5 Maintenance of Optoelectronic Switch Assembly..............................................................................10
Catalogue-3
Catalogue
Catalogue-2
Catalogue
Catalogue-3
Catalogue
Catalogue-4
Security Information
This chapter introduces the safety symbols used in the service manual and their meanings. It summarizes
the safety hazards and precautions when using the instrument, as well as the labels and specific meanings
attached to the instrument, and lists whether the content of toxic or hazardous substances or elements in
the instrument meets relevant standards.
Security Information-1
Security Information
Safety symbol
Various safety symbols are used in this service manual and the analyzer to remind you of the things you
need to be aware of during operation. As shown in the following table:
Keep away
Transport package shall be kept away from rain.
from rain
ISecurity Information-2
Security Information
Safety precautions
Introduction
For use of this instrument safely, please read the following safety precautions carefully. Any operation
that violates the following safety precautions may result in personal injury or damage to the instrument.
Warning:
In all cases marked with this warning sign, the user manual is required to clarify the
nature of the potential hazard and any countermeasures that must be taken. If you do
not follow the instructions in this user manual, the protective measures provided by
this instrument may be invalid.
Prevent burns:
Security Information-3
Security Information
Do not touch the light source box after the system is turned on.
When replacing the halogen lamp, the lamp must be replaced after the power is
turned off and wait at least 20 minutes for the halogen lamp to cool down,
otherwise the high temperature halogen lamp and the light source box may cause
burns.
Disposal of waste
Please observe the following precautions to dispose waste water to prevent environmental pollution and
personal injury caused by waste water.
Biological infection risk:
Some substances in reagents, controls, calibrators, cleaning fluids, or waste liquids
are subject to pollution regulations and emission standards. Please comply with
local emission standards and consult the relevant reagent manufacturer or
distributor.
When disposing waste, be sure to wear gloves and overalls to prevent infection,
and wear protective glasses if necessary.
Security Information-4
Security Information
Warning:
Disposal of instrument
Please dispose discarded equipment as per the following requirements.
Warning:
Security Information-5
1 System Overview
System Overview-1
System Overview
1.1Overview
The full name of this product is BK-200mini automatic chemistry analyzer, which is used for
quantitative analysis of clinical chemical components of serum, plasma, urine, cerebrospinal fluid
and other samples. The analyzer consists of analysis department, operation department (computer
system), result output department (printer), accessories and consumables.
1.2Overall Structure
The internal structure of the analyzer adopts the scheme of "two trays + one needle + one
stirrer", which is specifically a reaction tray, a reagent & sample tray, a reagent& sample needle
and a stirrer. One reagent & sample needle is used for adding sample, reagent 1 and reagent 2, and
one stirrer is used for reagent stirring and sample stirring. The optic-electronic measurement
module adopts the method of post-splitting to conduct real-time photoelectric acquisition of the
reaction cup. During the test, the automatic cleaning module is responsible for the automatic
cleaning of the reaction cup.
1.2.1Overall Appearance
System Overview-2
System Overview
System Overview-3
System Overview
1.2.2Composition of Analyzer
System Overview-4
System Overview
Name Note
Reagent &sample It is divided into reagent and sample locations, reagent bottles and sample cups
plate unit can be placed respectively, and the refrigerating temperature in the inner ring is
2~8℃.
Reaction plate 48 reaction cups are fixed and the reaction temperature is suitable and constant .
unit
Precision It can realize the precise extraction and discharge of reagent or sample.
sampling unit
Automatic The reaction cup can be cleaned automatically in three stages to realize the reuse
cleaning unit of the reaction cup.
Optic-electronic Optical path component uses mode of "first absorption then spectroscope "to
measurement unit realize the measurement of eight wavelengths.
refrigeration The reagent and samples were cooled by air for 24 hours at a temperature of
component 2~8℃.
Piston pump Provides power and control over the absorption and discharge of samples or
component reagents precisely.
Reagent & To drawn the reagent or sample from the reagent & sample tray and then
sample arm discharge it into the reaction cup to realize the sampling and cleaning action.
component
Stir component Stir the reagent and sample mixture in the reaction cup.
Cleaning arm To control the movement of the cleaning arm, and to clean the reaction cup in
component three stages automatically .
Pump & Valve Control the filling and discharging of reaction cup during automatic cleaning.
component
Note: Please refer to chapter 4 for the location of refrigeration components and the replacement of
each component in the diagram.
1-Piston pump. 2-Cleaning arm. 3-L frame. 4-Reaction tray. 5-Reagent&sample arm.
6-Cleaning tank 1. 7-Reagent&sample tray. 8- Circuit board assembly. 9-Switching
power supply unit. 10-Miniature diaphragm pump. 11-Valve. 12-Halogen lamp.
13-Optical path component. 14-Cleaning tank 2. 15-Mixing arm. 16-Switch Power .
Figure1-6 Structure of movement
System Overview-5
System Overview
System Overview-6
2 System Performance and Test Progress
Wavelength 340~800nm
Accuracy ±1nm
Basic
features Reaction Temp 37℃±0.2℃
Accuracy 0.0001
Liner: Factor, One point line, Two point line and Multi-points
Calibration line.
Non-Linear: Spline, Polygonometry, Logit-log4p, Logit-log5p.
Real time QC, Westgard multi rule, Cumulative sum check,
QC
Twin Plot(2D)
Automatic
Automatic washing sample probe, cuvettes
Washing
Mixing Speed adjustable stirrer with teflon coating.
2.1.5 Configuration
Display
17 inches and above, DPI is more than 1366 x768 resolution.
Operating System
Windows 7 and above, 32-bit or 64-bit. Microsoft Network Framework 3.5 and analytics
software have been installed. It is recommended to install the Microsoft Office Access
software.
Computer Configuration
Must be a brand machine, CPU frequency is more than 2.80GHz, hard disk≥80G, memory
≥2GB.
Communication Interface
TCP/IP internet, RS-232, USB2.0 port.
Printer
Printer requirements: supports inkjet, laser (black and white) printers
Data Input
Keyboard, mouse, strip code scanner, remote maintenance system (TCP/IP network interface
using static IP address)
LIS:HL7、ASTM1394(TCP/IP network or serial interface using static IP addresses)
Data Output
Display, Printer, Remote maintenance system (TCP/IP network interface using static IP
address), LIS system
Data Record
Hard disk, USB interface
3.1 Overview
This chapter mainly describes the operating environment, installation steps and precautions of the
analyzer to guide the installation
Warning:
The instrument will not be able to guarantee normal operation and the accuracy of
test data in an environment other than the above conditions. If the temperature and
humidity cannot meet the above requirements, please use air conditioning
equipment and humidification equipment.
During the operation of the instrument, heat will be generated and discharged
through the back of the instrument. The working environment should be well
ventilated and ventilation equipment should be used when necessary. However,
avoid direct airflow to the instrument, otherwise it may affect the accuracy of the
instrument test.
Warning:
Dispose of the waste water from the instrument in accordance with local
discharge standards. When installing the waste pipes, be sure to wear gloves and
overalls to prevent infection, wear protective glasses if necessary.
Warning:
The water quality must meet the water supply requirements. Otherwise,
insufficient water purity may affect the test results.
Before unpacking, please check the anti-tilting transportation monitoring label of the package.
When the label is in normal state, the next step will be carried out. If the window on the
anti-tilting label turns red, indicating that the goods are tilting, please immediately contact the
company's customer service center to confirm the status of the instrument.
3.5.2 Unpacking
1. Remove the analyzer and accessory boxes from the truck (forklift is recommended).
Installation Requirements and Steps-5
Installation Requirements and Steps
2. After checking that the anti-tilting label is correct, remove the waterproof film on the upper side
of the packing box and cut the upper packing belt with scissors. After unpacking, please check the
packing list, including: analyzer, accessory box, pure water barrel, computer (optional), display
(optional), printer (optional).
Figure3-7 Accessory
Figure3-8 Analyzer
Remove the pearl cotton, and then open the waterproof film.
Place the analyzer in where that meets the requirements of the installation environment.
Figure3-10 Power
The switch is turned upward for "on" and downward for "off".
2. Turn on the cooling switch (located at the lower left of the analyzer, marked by "Cooling
Power").
3. Turn on the main control switch (located at the lower left of the analyzer, marked by "Main
Power").
Step 1: Click the button in the lower left corner of the computer, as shown in the Figure
below, to find the control panel.
Figure3-13
Step 2: Click to open the control panel and find the Programs as follows.
Figure3-14
Step3:Click to open "Programs and Features" to see if there are Microsoft .NET Framework 3.5,
as shown below:
Figure3-15
Step 4: If the computer does not have a 3.5 frame installed, you need to install it manually.
Figure3-16
Step 2: Open the folder to find the NetFx35.exe file, you can install.
Figure3-17
Installation Steps
Step 1: the instrument application software installation CD into the computer's drive, find the
biochemical control software files .
Step 1: put the instrument software installation CD into the computer's CD-ROM and find the
Step 5: Confirm the installation, and click next to install. The installation process is shown in
the figure below.
Figure3-24 Config.ini
Step 8: Open and paste the file in the installation directory D: \ Program Files \ Analyzer
software, as shown in figure 3-25:
IP Address Configuration
The steps of IP address setting are as follows:
Step 1: Right click the " " tool in the lower right corner of the computer, click[Network
and Sharing center ], as shown in the figure :
Figure3-26
Step 2: Click[ Local Area Connection], and the dialog box for local connection status pops up,
as shown in figure 3-27.
Step 3: Click "Properties", and the local connection properties dialog box pops up, as shown
in figure 3-28.
Figure3-27 Figure3-28
Step 4: Double-click "Internet protocol version 4(TCP/IPv4)" and enter the IP address as
follows:
Figure3-29
Step 5: Click "OK" and the IP address is set.
Power Set
In order to avoid the influence of computer dormancy on the test, it is necessary to cancel the
dormancy setting of the computer. The steps are as follows:
Step 1: Open the control panel and find the [Power Options].
Figure3-30
Step 2:Select the[Balance] in the preferred plan and click[Change Plan Setting].
Figure3-31
Step 3: Windows7 installation, the default is to set the computer to sleep state, the settings are
as follows.
Figure3-32
Step 4: Set "Never" to both [ Turn off the display] and [Put the computer to sleep], then click
[Save changes] as shown in the Figure below.
Figure3-33
Step 5: After setting, [Save Changes] button is ashed, as shown below.
Figure3-34
1 Run the desktop icon . When you run the software for the first time, it will tip On
line setup, as shown in figure 3-35. Click "OK", the dialog box shown in figure 3-36 will pop up
Installation Requirements and Steps-16
Installation Requirements and Steps
and then click the software configuration. If the following figure 3-37 dialog box appears, the
software configuration is successful.
2 Run the icon again , and input the user name and password , click the button
Note:
If the password of the ordinary permission user is forgotten, you can log in the
system through the identity of the advanced permission user, delete the user
name, and then reset. Or contact the company's customer service department or
regional distributor. If the advanced user password is forgotten, please contact
the company's user service department or your regional distributor.
3 After the correct login and power-on detection are normal, the prompt box shown below is
displayed. After clicking “OK”, the instrument will to start maintenance operation. After the
perform is completed, the instrument displays the main interface of the operation software. At this
point, the boot process ends. If the environment is found to be inconsistent during the boot
detection process, a message will pop up. Please take corresponding measures according to the
information displayed on the interface.
Installation Requirements and Steps-17
Installation Requirements and Steps
Warning:
After the analyzer is powered into standby state, each part is not in the
initial position, you need to enter the software and click the initialization
command to perform an initialization operation!
To ensure accurate test results, please display "standby" in the system
status area and have been on for about 20 minutes before starting the test
operation to ensure stable light source and temperature control.
For the first time, please exhaust the water pipe for 20 times to ensure
the air bubbles in the pipe are emptied.
During the sample test, click in the menu bar to monitor the status of the sample
tray, reagent tray, and reaction tray in real time, as shown in figure 3-40 b).
a) Sample condition
b) Status monitor
Figure3-40 Sample testing
Sample tray monitoring: Click “Sample Status” under the “Monitor” form to display the
status of the sample tray on the left side of the form, as shown in figure 3-41, where the sample
tray uses different colors to distinguish the status of the sample. After you have applied for a
sample test and placed the required samples correctly, you can start the test.
Reagent tray monitoring: Click “Reagent Status” under the “Monitor” form to display the
status of reagent tray on the left side of the form, as shown in figure 3-42:
The reagent tray indicates the reagent placement number according to the serial number.
When the reagent is detected by the instrument, the software automatically calculates the
remaining amount of the reagent and displays it in the reagent information. In the reagent tray:
white indicates idle, yellow indicates less reagent, green indicates sufficient reagent, and red
indicates no reagent.
Reaction tray monitoring: The reaction tray displays the status of the reaction in real time
during the sample detection process. Click on “Reaction Status” under the “Monitor” form, as
shown in figure 3-43, where different colors indicate that the cuvette is in different working status.
Introduction of Module-1
Introduction of Module
Introduction of Module-2
Introduction of Module
Maintenance Steps
1 Turn off the power supply of the whole machine to ensure that all moving parts on the
workbench are in non-working state.
2 Open the top cover and unscrew the screws ST3.5*16 fixed on both sides of the top cover with a
cross screwdriver (such as screw 1 and 2 in the figure above ) to loosen the air spring.
3 Hold the top cover by hand, unscrew screw ST3.5*13 (such as screw 5 and 6 in the picture)
fixed on the hinge on one side of the top cover with a cross screwdriver, and loosen the hinges.
4 Lift the top cover back and up, then remove the top cover.
5 Reverse operation of the above process to install the top cover.
Adjustment and Validation
The gap shall be adjusted after the installation of the top cover. If the gap is uneven or there is
interference, the fixing screw of the top cover and hinge shall be adjusted appropriately.
Maintenance Steps
Introduction of Module-3
Introduction of Module
1 Unscrew screws M4*10 with Cross Screwdriver on the rear panel (such as screw 1-6 in the
figure above).
2 Hold the rear panel and pull it out.
3 Reverse operation of the above process to install the rear panel.
Adjustment and Validation
Nothing
Maintenance Steps
1 Open the top cover of the analyzer, remove the reaction tray cover and the reagent & sample
tray cover.
2 After removing the plug, remove 7 screws M4*10 with a Cross Screwdriver (screws 1-7 as
shown in the picture), rotate the stirrer and reagent & sample needle to the non-interference
position and then remove the two panels in turn.
3 Reverse operation of the above process to install the face panels.
Adjustment and Validation
When installing the panel, make sure the panel fits together. If the gap is large, hold on to the two
panels to balance the gap, and then tighten the screws of the face panel.
Maintenance Steps
1 Remove the rear panel first(Refer to 4.1.3 Maintenance of Rear Panel for details)..
2 Unplug the grey flat cable A,B and AD panel power line from the back of the analyzer, and
unplug the power line from the communication interface, and then loosen the screw M4*20 fixing
the circuit board assembly from the face panel with a cross screwdriver..
Introduction of Module-5
Introduction of Module
5 Remove 3 plugs from the housing fixing holes on the left, right and rear sides of the housing.
Use a cross screwdriver to unscrew 3 screws M4*14 in the housing fixing holes and place them
properly, and then loosen the 6 screws M4*14 which are used to fix the housing fixing frame on
the baseboard .
6 Unscrew 2 screws M4*18 and 1 screw M4*16 on the baseboard and place properly .
7 Unscrew the screws fixing the L frame and the power switch assembly from the baseboard and
push the housing fixing frames, L frame and the power switch assembly inward to ensure
non-interference with the housing .
8 Two people support the housing with their hands and move it to the top of the analyzer.
9 Reverse operation of the above process to install the housing .
Warning:
In the process of disassembling the housing, please pay attention to avoid
colliding with electronic components on the circuit board assembly, avoid
the power box scratching the housing, and avoid the cleaning fixing shaft
colliding the housing.
In the process of installing the housing: please pay attention to avoid
colliding with electronic components on the circuit board assembly, avoid
the power box scratching the housing, ,avoid the housing holding down
any power line or pipe, and avoid the cleaning fixing shaft colliding the
housing.
Adjustment and Validation
When installing the housing, make sure that there is no interference to internal power lines and
pipes (no line is held down), then screw down the fixing screws.
Maintenance Steps
1 Open the top cover and unscrew 5 screws ST3.5*16 (screw 1~5 as shown in the Figure ) with a
cross screwdriver.
2 Hold the top cover and remove the gas spring.
3 Install the new gas spring (pay attention to the installation direction of the gas spring, as shown
in the Figure).
Adjustment and Validation
Nothing
Introduction of Module-7
Introduction of Module
Introduction of Module-8
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels(Refer to 4.1.4 Maintenance of
Face Panel for details).
3 Unplug the temperature sensor power line form AD Board (see Figure 5-1AD Board Diagram
for interface position in 5.3.1 AD Board), clean the thermal conductive glue around the
temperature sensor hole with the blade, and pull the temperature sensor from the reaction tray .
4 Take a new temperature sensor , evenly apply thermal conductive glue and install it into its
installing hole. During installation, push it to the deepest place.
5 Connect the temperature sensor power line, and reverse operation of the above process to install
the face panels.
Adjustment and Validation
Check whether the temperature monitoring is normal.
Introduction of Module-9
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).
3 Unscrew the fastening screw, remove the reaction cup assembly and place properly.
4 Unscrew 3 screws M4*12, remove reaction cup positioning plate assembly and place properly.
5 Loosen the M4*6 screw which fixing the fiber on the reaction tray, take out the end of the fiber
and place it properly.
6 Unplug power lines of the temperature sensor and heater wire(see Figure 5-1AD Board Diagram
for interface position in 5.3.1 AD Board).Unscrew 3 screws M4*14 and remove the reaction tray
assembly. Then the 3 screws M3*14 under the reaction tray assembly were unscrewed and the
halogen lamp assembly was removed from the reaction tray assembly.
7 Take a new reaction tray assembly and fix the halogen lamp assembly to the reaction tray
assembly with 3 screws M3*14. Note that the 3 screws should be respectively through the heat
insulation washer between the reaction tray and the halogen lamp fixing plate. The halogen lamp
mirror tube should be aligned with the hole on reaction tray assembly .
8 Fix the reaction tray assembly to the hex spacer of the reaction tray with 3 screws M4*14 . Plug
power lines of the temperature sensor and heater wire. Fix the fiber to the reaction plate with a
screw M4*6. Make sure that the fiber fixing hole and the halogen light source are basically in the
same plane and in the same straight line.
9 Adjust the position of the positioning plate relative to the reaction tray , tighten 3 screws M4*14
of the assembly of the reaction tray , and install the positioning plate of the reaction tray .
10 Reverse operation of the above process to install reaction cup assembly, face panel and other
parts.
Adjustment and Validation
After installing the reaction tray, the position of the tray must be adjusted, and the positioning
plate of the reaction tray can be installed after the adjustment.
After the replacement, it's necessary to do adjustment and validation for the position of reaction
tray according to chapter 7.2.2.2 &7.2.2.3, and do adjustment and validation for the positions of
the needles (such as reagent&sample needle, stirrer and cleaning needles)in the reaction cup
according to chapter 7.2.2.1, and also check the positions of needles in cleaning tank and in
reagent&sample tray .
Introduction of Module-10
Introduction of Module
If the reaction tray optoelectronic switch assembly doesn’t work, then replace it.
Tools of Maintenance
Name No. Quantity
Cross Screwdriver / 1 pcs
Allen Wrench / 1 set
Disassembly Diagram
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels ,rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).
3 Unscrew the 2 screws M3*8 fixing the optoelectronic switch assembly behind the analyzer,
remove the assembly, be careful not to drop the screws into the machine.
4 Unscrew the 2 screws M3*10 fixing the optoelectronic switch ,unplug the power line of the
optoelectronic switch and remove the optoelectronic switch .
5 Fix the new optoelectronic switch to the bracket with 2 screws M3*10, spring washers, flat
washers, and another side spring washers and nuts orderly.
6 Fix the new optoelectronic switch assembly to the baseboard with 2 screws M3*8, spring
washers and flat washers orderly.
7 Adjust the position of optoelectronic switch , plug the power line of the optoelectronic switch
(see Figure 5-1AD Board for interface position in 5.3.1 AD Board). Reverse operation of the
above process to install housing, rear panel and face panel.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of reaction
tray according to chapter 7.2.2.2 &7.2.2.3, and do adjustment and validation for the positions of
the needles (such as reagent&sample needle, stirrer and cleaning needles)in the reaction cup
according to chapter 7.2.2.1. and also check the positions of needles in cleaning tank and in
reagent&sample tray .
Note:
Pay attention to the screw fixing the optoelectronic switch should not be too
tight to avoid crushing the switch.
Introduction of Module-11
Introduction of Module
Tools of Maintenance
Name No. Quantity
Cross Screwdriver / 1 Pcs
Allen Wrench / 1 Set
Disassembly Diagram
Warning:
Screws and washers should be prevented from falling into the machine
during disassembly and assembly.
Maintenance Steps:
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).
3 Unplug the power line of motor, unscrew the 4 screws M4*14 fixing the bracket, remove the
bracket and motor assembly, be careful not to drop the screws into the machine.
4 Unscrew the 4 screws M3*8 fixing the stepping motor assembly, remove the assembly.
5 Unscrew the 2 screws M4*8 fixing the synchronous pulley, remove the pulley.
6 Take a new stepping motor and fix the synchronous pulley on the motor shaft with 2 screws
M4*8. Note that the screw should be fixed on the flat of the motor shaft .
7 Fix the new stepping motor to the bracket with 4 screws M3*8, spring washers and flat washers
orderly.
8 Fix the bracket to the baseboard with 4 screws M4*14, spring washers and flat washers orderly.
And ensure that the belt and the pulley should be properly tightened, that is, when the driving
component is twisted by hand, the movement is smooth and there is no noise.
9 Plug the power line of stepping motor(see Figure 5-1AD Board for interface position in 5.3.1
AD Board).
10 Reverse operation of the above process to install housing, rear panel and face panel.
Adjustment and Validation
Nothing.
Introduction of Module-12
Introduction of Module
When the reaction cup is damaged or the dirty cup state shows in the software reaches
more than 1/3, new reaction cups shall be replaced.
Tools of Maintenance
Name No. Quantity
Medical Rubber Gloves / 1 Pair
Maintenance Steps:
1 Turn off the main power switch of the analyzer and remove the cover of the reaction tray.
2 Unscrew the fastening screw.
3 Take off six groups of reaction cups in turn.
4 Reverse operation of the above process to install the new reaction cups.
Introduction of Module-13
Introduction of Module
Disassembly Diagram
Introduction of Module-14
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.。
2 Open the cover of reagent &sample tray ,unscrew the handle of the reagent & sample tray
counterclockwise, lift and remove the reagent & sample tray assembly.
3 Fix the locating hole of the new reagent & sample tray assembly to the locating pin and tighten
the handle.
4 Place the cover of the reagent &sample tray.
Adjustment and Validation
Nothing.
Disassembly Diagram
Introduction of Module-15
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels ,rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details). Lift the reagent & sample tray assembly.
3 Discharge the condensate in the reagent & sample pot completely .
4 Unplug the power lines of refrigeration assembly, such as the power line of peltier and fan.
5 Cut off the cable tie at the condensate junction of the reagent & sample pot and unplug the
condensate pipe.
6 Unscrew the 3 screws M4*8 fixing the reagent tray plate, remove the plate, be careful not to
drop the screws into the machine.
7 Unscrew the 3 screws M4*30 fixing the reagent & sample pot, remove the pot and refrigeration
assembly, be careful not to drop the washer into the machine.
8 Unscrew the 8 screws M4*14 fixing the refrigeration assembly, remove the refrigeration
assembly(see chapter 4.3.5 for detail).
9 Take a new reagent & sample pot assembly ,use 8 screws M4*14 and nuts to fix the reagent &
sample pot assembly, peltier and cooling fin together from the inside of the pot. Drop sealant on
the nut. When dropping sealant, the sealant should completely cover around the nut and there
should be no big bubbles to ensure the sealing of the reagent & sample pot and prevent leakage.
10 Use 3 screws M4*30 to pass the silicone pad, reagent & sample pot and washer to fix the
assembly on the hex spacer.
11 Add insulation sponge to the rim of the reagent & sample tray.
12 Fix the reagent&sample tray assembly on the driving assembly with 3screws M4*8, spring
washers and flat washers.
13 Plug the power lines of peltier and fan.
14 Connect the condensate water pipe, the joint is wrapped with insulation sponge and tied with
cable tie.
15 Reverse operation of the above process to install reagent&sample tray assembly, housing, rear
panel, face panel, and other parts.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of
reagent&sample needle according to chapter 7.2.2.1 .
Introduction of Module-16
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details). Lift the reagent & sample tray assembly.
3 After removing the reagent & sample pot assembly, place it upside down.
4 Unscrew the 8 screws M4*14 fixing the refrigeration assembly, remove the refrigeration
assembly.
5 Remove the old peltier from the cooling fin.
6 Apply a thin layer of heat-conducting silicon grease to both sides of the new peltier. The peltiers
are installed with the refrigeration surface (with character ) facing the reagent & sample pot
assembly, 8 screws M4*14 and nuts were used to fix the reagent & sample pot assembly, peltier
and cooling fin together from the inside of the pot. Drop sealant on the nut. When dropping
sealant, the sealant should completely cover around the nut and there should be no big bubbles to
ensure the sealing of the reagent & sample pot and prevent leakage.
7 Reverse operation of the above process to install reagent&sample pot assembly, reagent &
sample tray assembly, housing, rear panel, face panel, and other parts.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of
reagent&sample needle according to chapter 7.2.2.1.
Introduction of Module-17
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).
3 Unscrew the 2 screws M3*8 fixing the optoelectronic switch assembly behind the analyzer,
remove the assembly, be careful not to drop the screws into the machine.
4 Unscrew the 2 screws M3*10 fixing the optoelectronic switch, unplug the power line of the
optoelectronic switch and remove the optoelectronic switch.
5 Fix the new optoelectronic switch to the bracket with 2 screws M3*10, spring washers, flat
washers, another side spring washers and nuts orderly.
6 Fix the new optoelectronic switch assembly to the baseboard with 2 screws M3*8, spring
washers and flat washers orderly.
7 Adjust the position of optoelectronic switch , plug the power line of the optoelectronic switch
(see Figure 5-2 Driving Module for interface position in 5.3.2 Driving Module). Reverse operation
of the above process to install housing ,rear panel and face panel.
Note:
Do not pull the photoelectric switch connection after installation.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of
reagent&sample needle according to chapter 7.2.2.1 .
Introduction of Module-18
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).
3 Unscrew the 4 screws M4*14 fixing the stepping motor assembly from the reserved hole under
the baseboard, remove the assembly.
4 Unscrew the 2 screws M4*8 fixing the synchronous pulley, remove the pulley.
5 Take a new stepping motor and fix the synchronous pulley on the motor shaft with 2 screws
M4*8. Note that the screw should be fixed on the flat of the motor shaft. Fix the stepping motor
assembly to the baseboard with 4 screws M4*14, spring washers and flat washers orderly. And
ensure that the belt and the pulley should be properly tightened, that is, when the driving
component is twisted by hand, the movement is smooth and there is no noise.
6 Plug the power line of stepping motor(see Figure 5-2 Driving Module for interface position in
5.3.2 Driving Module).
7 Reverse operation of the above process to install housing, rear panel and face panel.
Note:
Screws and washers should be prevented from falling into the machine during disassembly and
assembly.
Do not remove the two screws fixing the shock pad of the motor, otherwise it will cause drive
failure.
The screws must be tightened, not loosened.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of
reagent&sample needle according to chapter 7.2.2.1 .
Introduction of Module-19
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).
3 Unscrew the inlet and outlet water pipes of the plunger pump, unplug the power lines of motor
and photoelectric switch.
4 Unscrew the 2 screws M4*12 fixing the bracket, remove the plunger pump assembly.
5 Unscrew the 2 screws M3*8 fixing the plunger pump, remove the plunger pump, be careful not
to drop the screws or washers into the machine.
6 Reverse operation of the above process to install the new plunger pump, the power lines of
motor and photoelectric switch(see Figure 5-2 Driving Module for interface position in 5.3.2
Driving Module).
7 Install inlet and outlet water pipes (Teflon pipes), avoid pipe bending and extrusion during
installation. Pay attention to the inlet pipe is connected with out end of valve V1.
8 Reverse operation of the above process to install housing ,rear panel and face panel.
Adjustment and Validation
Nothing.
Introduction of Module-20
Introduction of Module
Introduction of Module-21
Introduction of Module
Steps of Disassembly
1 Make sure the analyzer is powered down.
2 Open the cap.
3 Unplug the Teflon pipe connected to the reagent & sample needle assembly.
4 Loosen the upper fixing screw on the reagent &sample needle assembly, lift and remove the
reagent & sample needle assembly from the anti-collision needle seat.
5 Take the new reagent & sample needle assembly and pass it through the nut, cross arm and
anti-collision needle seat. Fix the new reagent & sample needle assembly with the anti-collision
needle seat by turning the upper fixing screw. Be careful not to tighten it too tightly, make sure the
needle to lift up normally.
6 Reverse operation of the above process to install Teflon pipe and cap.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of
reagent&sample needle to reaction tray, reagent &sample tray and cleaning tank according to
chapter 7.2.2.1.
Note:
When plug or unplug the Teflon pipe, pay attention to the silicone pipe at the connection not to
fall off.
When removing or installing the reagent&sample needle assembly, pay attention to the silicone
pad in the anti-collision needle seat not to fall off.
The reagent & sample needle assembly should be handled gently and stored properly to avoid the
needle being bent or damaged.
When installing the reagent & sample needle assembly, check whether the reagent & sample
needle is running smoothly or not. In case of stuck, readjust the needle and anti-collision needle
seat.
Occasion of Maintenance
If the stepping motor doesn’t work, then replace it.
Introduction of Module-22
Introduction of Module
Tools of Maintenance
Replacement Steps:
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).
3 Unplug the grey flat cable on transfer interface board, unscrew the Teflon pipe connected with
plunger pump. Unscrew the 2 screws M5*20 fixing the reagent &sample arm assembly and take
off it.
4 Unscrew the 4 screws M4*12 fixing the stepping motor assembly, remove the assembly.
5 Unscrew the 2 screws M4*8 fixing the synchronous pulley, remove the pulley.
6 Take a new stepping motor and fix the synchronous pulley on the motor shaft with 2 screws
M4*8. Note that the screw should be fixed on the flat of the motor shaft. Fix the stepping motor
assembly to the baseboard with 4 screws M4*12, spring washers and flat washers orderly.And
ensure that the belt and the pulley should be properly tightened, that is, when the driving
component is twisted by hand, the movement is smooth and there is no noise. Plug the power line
of stepping motor(see Figure 5-2 Driving Module for interface position in 5.3.2 Driving Module).
7 Reverse operation of the above process to install reagent&sample arm assembly, housing, rear
panel, face panel and other parts, connect Teflon pipe and grey flat cable as they were.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of
reagent&sample needle to reaction tray ,reagent &sample tray and cleaning tank according to
chapter 7.2.2.1 .
Note: The maintenance of stepping motor in left and right direction is same as the stepping motor
in up and down direction.
Introduction of Module-23
Introduction of Module
Replacement Steps:
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details). Unplug the grey flat cable on transfer interface board, unscrew the teflon pipe
connected with plunger pump. Unscrew the 2 screws M5*20 fixing the reagent &sample arm
assembly and take it off.
3 Unscrew the 2 screws M3*6 fixing the optoelectronic switch assembly, unplug the power line of
optoelectronic switch, remove the assembly.
4 Fix the new optoelectronic switch assembly to the reagent &sample arm with 2 screws M3*6,
plug the power line of optoelectronic switch (see Figure 5-2 Driving Module for interface position
in 5.3.2 Driving Module).
5 Reverse operation of the above process to install reagent&sample arm assembly, housing, rear
panel, face panel and other parts, connect Teflon pipe and grey flat cable as they were.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of
reagent&sample needle to reaction tray ,reagent &sample tray and cleaning tank according to
chapter 7.2.2.1 .
Introduction of Module-24
Introduction of Module
Replacement Steps:
1 Make sure the analyzer is powered down.
2 Open the top cover, open the cap .
3 Lift the FPC locking device (Note: both ends of the locking device are lifted together to prevent
one end from breaking with excessive force), and lift the FFC line vertically upward from the
fixed hole.
4 Hold the terminal of the signal line and pull it out.
5 Gently lift the needle and block from the optoelectronic switch and place them outside the
optoelectronic switch.
6 Remove 2 screws M3*6 with a cross screwdriver and remove the liquid level detection board.
During the process, avoid the photoelectric switch or the liquid level detection board hitting the
block.
7 After fixing the new liquid level detection board with two screws M3*6, connect FFC line and
signal line in turn, and then install the cap.
Adjustment and Validation
After replacing the liquid level detection board, adjustment and validation shall be conducted on
the position of reagent& sample needle to the reaction tray, the reagent & sample tray and the
cleaning position according to the methods and steps in the 7.2.2 .
Note:
The FFC lines’ direction is as follows:
Introduction of Module-25
Introduction of Module
5 The FFC line and Teflon tube are drawn from the bottom of the spline shaft, and then the FFC
line is drawn from the fastening seat.
Introduction of Module-26
Introduction of Module
6 Take the new FFC lines, put printing literal down, on the no printing literal mark 1, 2
identification, and setφ3 length 6mm heat shrinkable tube at both ends of the FFC line.
7 Wrap one end of FFC line with paper tape and pass it from the bottom end of spline shaft to the
top end. FFC line is arranged in line order of label no. 1 and label no. 2, and fixed to the FPC
locking device of liquid level detection board .
8 The FFC line end at the bottom of the spline shaft passes through the cable tie fixing seat from
bottom to top and is fixed to the FPC locking device of the transfer interface board .
Introduction of Module-27
Introduction of Module
9 Cover the cap and reverse operation of the above process to install reagent&sample arm
assembly, housing ,rear panel, face panel and other parts ,connect Teflon pipe and grey flat cable
as they were.
Note:
There is lubricating oil in the spline shaft. When the FFC line and Teflon
tube are inserted or extracted from the spline shaft, please protect the
FFC line and Teflon tube to prevent oil contamination or blockage of the
pipeline, or poor FFC contaction.
Adjustment and Validation
1 Power on the analyzer.
2 Do adjustment and validation about the position of reagent& sample needle to the reaction tray,
the reagent & sample tray and the cleaning position according to the methods and steps in the
7.2.2 .
Introduction of Module-28
Introduction of Module
Steps of Disassembly
1 Make sure the analyzer is powered down.
2 Hold the top end of the stirrer, remove the M2.5*6 screws with a cross screwdriver, and pull out
the stirrer.
Introduction of Module-29
Introduction of Module
3 Hold the upper end of the new stirrer, point the mixing rod at the mounting hole, press upward
until the stirrer can not move, and fix it with two screws M2.5*6.
Note:
When installing the stirrer, it is necessary to keep the stirrer upright and do not apply force at an
oblique angle. The left and right screws should be tightened in turn with several fine adjustments
instead of being tightened once.
After removing the stirrer, do not touch the blade of the stirrer with your hands.
Adjustment and Validation
After replacing the stirrer, there is no need to adjust the horizontal or height parameters, but make
sure the stirrer is in the vertical state .
Replacement Steps:
1 Make sure the analyzer is powered down.
2 Open the top cover, open the cap.
3 Remove the stirrer and place it in the box or other safe place (refer to the maintenance of stirrer
in 4.6.3 for details).
4 Loosen the 2 screws M2*4 fixing the stirring motor assembly, unplug the power line of the
stirring motor and remove the stirring motor assembly.
5 Fix the new stirring motor assembly to the stirring arm with 2 screws M2*4.
6 According to the reverse order of the above steps, plug the power line of stirring motor , and
install the stirrer, cap and other parts.
Adjustment and Validation
After replacing the component of the stirring motor, the following methods can be selected to
check whether the replacement is successful:
Click "rotate" in the "stirrer speed" command on the setting interface of the software instrument to
check whether the stirring motor assembly is running with normal sound.
Introduction of Module-30
Introduction of Module
If the speed is abnormal, it is necessary to check whether the power line of stirring motor is
correct or whether there is any problem with the assembly of the stirring motor.
Replacement Steps:
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details). Unplug the grey flat cable on transfer interface board. Unscrew the 2 screws M5*20
fixing the stirring arm assembly and take it off.
3 Unscrew the 2 screws M3*6 fixing the optoelectronic switch assembly,unplug the power line of
optoelectronic switch, remove the assembly.
4 Fix the new optoelectronic switch assembly to the stirring arm with 2 screws M3*6.
5 Plug the power line of optoelectronic switch (see Figure 5-2 Driving Module for interface
position in 5.3.2 Driving Module).
Introduction of Module-31
Introduction of Module
6 Reverse operation of the above process to install stirring arm assembly, housing ,rear panel, face
panel and other parts ,connect Teflon tube and grey flat cable as they were.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of stirrer to
reaction tray, reagent &sample tray and cleaning tank according to chapter 7.2.2.1.
Replacement Steps:
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details). Unplug the grey flat cable on transfer interface board. Unscrew the 2 screws M5*20
fixing the stirring arm assembly and take it off.
3 Unscrew the 4 screws M4*12 and spring washers that fixing the stepping motor assembly,
remove the assembly.
4 Unscrew the 2 screws M4*8 fixing the synchronous pulley, remove the pulley.
5 Take a new stepping motor and fix the synchronous pulley on the motor shaft with 2 screws
M4*8. Note that the screw should be fixed on the flat of the motor shaft. Fix the stepping motor
assembly to the stirring arm with 4 screws M4*12, spring washers orderly. And ensure that the
belt and the pulley should be properly tightened, that is, when the driving component is twisted by
hand, the movement is smooth and there is no noise. Plug the power line of stepping motor(see
Figure 5-2 Driving Module for interface position in 5.3.2 Driving Module).
6 Reverse operation of the above process to install stirring arm, housing, rear panel and face panel.
Introduction of Module-32
Introduction of Module
Disassembly Diagram
Introduction of Module-33
Introduction of Module
Steps of Disassembly
1 Make sure the analyzer is powered down.
2 Unscrew the cleaning compression screw, place it and the seal ring well, and pull out the
cleaning needle assembly.
3 Hold the single or double needles that need to be replaced and remove the connected pipes.
4 Loosen the M3*6 screw used for fixing the cleaning needle, and remove the single or double
needles that need to be replaced.
5 Replacement of double needles: hold the upper end of the new double needles, and pass through
the cleaning needle fixed seat, spring and cleaning needle fixed block in turn, until the cleaning
needle fixed block is located in the middle of the cleaning needle, then fix it with M3*6 screws.
Replacement of single needle assembly: hold the lower end of the new single needle, and then
pass through the cleaning needle fixed seat, cleaning needle fixed block and spring upward , until
the cleaning needle fixed block is located in the middle of the cleaning needle, then fix it with
M3*6 screw.
6 Reverse operation of the above process to install the cleaning needle assembly and the cleaning
compression screw.
Note:
When installing the cleaning needle, it is necessary to keep it upright and do not apply force at an
oblique angle. The screws should be tightened in turn with several fine adjustments instead of
being tightened once.
When each cleaning needle is removed, the corresponding water pipe must be marked, after
replacing the cleaning needle, connect the water pipe to the needle in the previous order.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of cleaning
needle to reaction cup, reagent &sample tray and cleaning tank according to chapter 7.2.2.1
Make sure the double needle of the cleaning needle is at the bottom of the cup and the single
needle is about 2mm from the bottom of the cup when the cleaning arm is running to the bottom
of the reaction cup.
Replacement Steps:
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).Unplug the grey flat cable on transfer interface board. Unscrew the 4 screws M4*20
fixing the cleaning arm assembly and take it off.
3 Unscrew the 4 screws M4*12 and spring washers that fixing the stepping motor assembly,
remove the assembly.
4 Unscrew the 2 screws M4*8 fixing the synchronous pulley, remove the pulley.
5 Take a new stepping motor and fix the synchronous pulley on the motor shaft with 2 screws
M4*8. Note that the screw should be fixed on the flat of the motor shaft.
6 Fix the stepping motor assembly to the cleaning arm with 4 screws M4*12, spring washers
orderly. And ensure that the belt and the pulley should be properly tightened, that is, when the
driving component is twisted by hand, the movement is smooth and there is no noise. Plug the
power line of stepping motor(see Figure 5-2 Driving Module for interface position in 5.3.2
Driving Module).
Introduction of Module-35
Introduction of Module
7 Reverse operation of the above process to install cleaning arm, housing ,rear panel and face
panel.
Adjustment and Validation
After the replacement, it's necessary to do adjustment and validation for the position of cleaning
needle to reaction cup, reagent &sample tray and cleaning tank according to chapter 7.2.2.1.
Replacement Steps:
1 Make sure the analyzer is powered down.。
2 Open the top cover of the analyzer and remove the face panels and rear panel (Refer to 4.1.3
Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel).
3 Unplug the power line of optoelectronic switch behind the analyzer, unscrew the screw M3*6
fixing the optoelectronic switch and remove it.
4 Fix the new optoelectronic switch assembly to the cleaning arm with screw M3*6 and spring
washer.(Note the adjustment when the optoelectronic switch is fixed: the block is in the
center of the optoelectronic switch assembly and there is no friction during the up and down
movement.)
Introduction of Module-36
Introduction of Module
5 Plug the power line of optoelectronic switch (see Figure 5-2 Driving Module for interface
position in 5.3.2 Driving Module).
6 Reverse operation of the above process to install rear panel, face panel.
Adjustment and Validation
Nothing.
Introduction of Module-37
Introduction of Module
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels, rear panel and housing (Refer to
4.1.3 Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel, 4.1.5 Maintenance of Housing
for details).
3 Remove the grey flat cables(A and B) on both sides of the optical path component, loosen the
M4*6 screw on the outside of the optical path component, and pull out the optical fiber from the
optical path component.
4 Loosen 2 screws M4*12 with an extended T-type allen wrench and remove the optical path
component.
5 Take a new optical path component and fix it on the baseboard with 2 screws M4*12.
6 One end of the optical fiber with slotted screw is connected to the optical path component and
M4*6 screw is used to tighten the optical fiber.
7 Reverse operation of the above process to connect grey flat cable and install housing, rear panel,
face panel and other parts.
Adjustment and Validation
After replacing the optical path component, do adjustment and validation according to 7.2.2.3
Adjustment of Light Base and 7.2.2.4 Adjustment of Voltage .
Replacement Steps
1 Make sure the analyzer is powered down.
2 Open the top cover of the analyzer and remove the face panels and rear panel (Refer to 4.1.3
Maintenance of Rear Panel, 4.1.4 Maintenance of Face Panel). Peel off the film, unscrew the 3 pcs
screws M4*12, remove the reaction cup positioning plate assembly and place well.
3 Loosen the M4*6 screw outside the optical path component and pull out one end of the fiber.
4 Loosen the M4*6 screw on the optical fiber fixing plate and pull out one end of the fiber.
5 Take a new optical fiber and connect one end with the slotted screw into the optical path
component, and the other end through the hole of the optical fiber fixing plate. Tighten the two
ends of the optical fiber are fastening with the M4*6 screw respectively. Note that it is necessary
to ensure that the fiber in the fiber fixing plate is basically in the same plane and straight line with
the halogen light source.
6 Reverse operation of the above process to install reaction cup positioning plate assembly, rear
panel, face panel and other parts.
Adjustment and Validation
After the replacement of optical fiber, do adjustment and validation of mechanical position, Light
Base and voltage according to 7.2.2.1, 7.2.2.3 and 7.2.2.4.
Introduction of Module-39
5 Hardware Circuit
Hardware Circuit-1
Hardware Circuit
5.1 Overview
This chapter describes the functions of the circuit boards of the analyzer.
Hardware Circuit-2
5.2 Schematic Circuit Diagram
Hardware Circuit-3
Hardware Circuit
5.3.1 AD Board
Figure5-1 AD Board
The testing range of front stage voltage:0.4V~2.8V.
The testing range of back stage voltage(not blocking the light):One-key gain calibration,the target
AD value is 48000.
The testing range of light blocking voltage: When using the blocking strip, voltage is required to
be about 10mV. When using the baffle, the voltage is required to be about 25mV (make sure the
AD value is about 150 and less than 200). If the voltage does not meet the requirements, adjust the
adjustable potentiometer in AD board.
Hardware Circuit-4
Hardware Circuit
Water System-5
Hardware Circuit
Hardware Circuit-6
Hardware Circuit
Hardware Circuit-8
6 Water System
Water System-1
Water System
6.1 Overview
The main functions of the analyzer water system are:
The inlet module provides pure water for the analyzer.
Provide pure water for automatic cleaning module of reaction cups and precise sampling
module.
The waste module discharges the waste water produced by the test.
The main content of this chapter is to introduce the working principle and maintenance method
of the analyzer water system.
OUT
Pump2
Solenoid IN
valve1
GND
Alarm1 Alarm2
Out1
Out2 In1
Water System-2
Water System
Water System-3
Water System
The waste water of cleaning reaction cup is discharged from "OUT 2", and the waste water of
cleaning stirrer and reagent & sample needle is discharged from "OUT 1".
Waste module mainly consists of the following parts
L Frame
Pipes, joints and other parts
High concentration waste mainly consists of reaction cup's cleaning waste water of step 1 and 2.
Low concentration waste mainly comes from:
Internal and external wall cleaning of reagent & sample needle
Cleaning of stirrer
Condensed water in reagent &sample tray
The schematic diagram of this section is shown in the figure.
6.3.5 Others
The analyzer water system includes three external interfaces, as shown in the figure.
Two outlets for discharging waste.
One inlet for providing pure water.
Water System-5
Water System
6.4.1 Overview
When the analyzer analyzer shows a software prompt message, engineer will confirm the cause of
the failure and replace the parts by analyzing the status of the analyzer. In principle, the pump,
valve, needle blocked detection, plunger pump and other electrical parts shall not be disassembled.
If the hardware and software are confirmed to be trouble-free, but the fault indication of the water
system remains unchanged, the corresponding equipment shall be disassembled for analysis and
replacement.
Before all disassembly actions, it is necessary to confirm that all pumps and valves in the water
system are closed, shut down the power supply of analysis department and shut down the main
power supply.
Table 6-1 Tool s for Maintenance
Name No. Quantity
Straight Screwdriver / 1 pcs
Cross Screwdriver / 1 pcs
Allen Wrench / 1 set
Cable Tie / Some
Diagonal Pliers / 1 pcs
Pipe Plier / 1 pcs
Water System-6
Water System
Water System-7
Water System
Water System-8
Water System
Note:
Prevent the liquid from dripping into the reaction tray and cups.
Steps of Assembly
Connect the inlet and outlet pipes of the pump according to the marks.
Install the pump to the sleeve.
Make sure the pump power connection is correct, that is, the positive and negative poles
cannot be connected in reverse.
Note:
Do not mix the gas and liquid pipelines. Do not mix the pipes of inlet
and outlet.
The positive and negative electrodes of the pump power supply cannot
be connected in reverse.
Water System-10
Water System
Water System-11
Water System
6.5.1 Pumps
No. Name Size Number Note
6.5.2 Valves
6.5.3 Joints
Water System-12
Water System
Plunger
4 A1428-2-200 B01902010304003 1 pcs
pump's joint
One end is connected with a TPU Pipe
Φ8-Φ4
with an I.D. of 8 mm and the other end
5 Straight 1 pcs
is connected with a TPU Pipe with an
Joint
I.D. of 6mm
One end is M6 thread, and another end
M6-Φ5Togg
7 connect pipe which I.D. is 4mm (M6 - B01902010403003 2 pcs
le joint
Φ 5 bend).
Nut for
8 M8,use with 4-M8-4 small joint 3 pcs
small joint
4-M8-4,The minimum outer diameter
is 4mm, the outer diameter of the
9 Small joint pagoda is 5.2mm, the inner diameter of B01905010403004 3 pcs
the hole is 2.4mm, and the total length
is 45mm.
Bulkhead
10 11-M16-12 B01905010403034 2 pcs
union
Nut for
11 bulkhead M16 B01905010403036 1 pcs
union
Bulkhead
12 8-M12-8 B01905010403035 2 pcs
union
Nut for
13 bulkhead M12 B01905010403005 1 pcs
union
M6-φ3.2
14 Straight One end is M6 thread, and another end 1 pcs
connect pipe which I.D. is 3.2mm
Joint
Threaded
15 6*4mm-01【PT1/8】 1 pcs
toggle joint
Straight joint
16 PC6-01 1 pcs
(PC Joint)
The minimum O.D. is 9.51mm,the
17 T-joint B01905010403013 2 pcs
maximum O.D. is 11.8mm
6.5.4 Pipes
Teflon Connection of
4 pipe 008T30-200-200 .I.D. plunger pump
B01903010408006
is2mm.O.D.is 3mm.
(PTFE) and valve V1
Silicone I.D. is 6.5mm , O.D.is Connection of
5 10mm, and the hardness is B01902010408004
pipe outlet
70A
Translucent blue pipe, that
PVC I.D. is 9.5mm , O.D.is Connection of
6 B02001010408107
pipe 14mm, and the hardness is cleaning tank
70A
Water System-14
7 Adjustment and Maintenance
[Instrument Check] is shown as Figure 7-2. About the reaction tray, sample tray and reagent
tray, [zero] means the automatic returning to 1st position of each tray's mechanical position. In the
checking process, click on [zero] of each tray, click on the positions of reagent & sample arm in
the reaction cup, sample tube and reagent bottle respectively, and observe that if the reagent &
sample needle is in the center of each 1st position .
[Mixing Arm] → [Cleaning Position ], loosen the set screws with flat point on the cross arm
of the stirring arm, install the stirrer on the cross arm, make the stirrer located in the middle of the
cleaning tank by adjusting the cross arm of the stirring arm, and fix the cross arm.Operate
reaction cup. If only the cleaning needle is in the center of the reaction cup, but other needles
are in the front or back of the reaction cup, then the position of the cleaning needle should
be adjusted, and the 4 adjusting screws of the cleaning arm and the relative position of the
reaction tray should be adjusted to make all the needles be in the center of the reaction cup.
After adjustment, tighten the sample & reagent arm and the adjusting screws of the cleaning arm.
The relative position of the needle and the reaction cup is shown in Figure 7-5:
Figure7-6 Adjusting Screw of Cleaning Arm Figure7-7 Locating Screw of Reaction Tray
Step 3:Click [Maintenance] and [Adjustment], then click the [Password] shows like Figure
7-8. Input the password “666666” to enter the adjustment.
adjustment interface is shown in figure 7-10. The adjusted relative position is shown in figure
7-11.
should be carried out. Click or , and then execute[Adjust Light Base] to obtain
optical alignment, so as to obtain the corrected optical curve.。
Note: "+1" means the light curve moves to the right, while "-1" means the light curve
moves to the left.
Step 5: If the requirements of optical curve are not met, repeat step 4 until the calibration
meets the requirements of optical curve.
Note: Light base ranges from 1 to 60 .
7.2.3 Washing&&Background
When the instrument has not been used for a long time or when a large number of dirty cups are
shown in the monitoring of the reaction tray, the washing&&background operation is required.
No response 1.Poor contact of the power plug 1. Detect the power input part wiring
after the 2. Instrument fuse burned out 2. Replace the fuse and check the line
instrument is
turned on
The instrument failure analysis and solution for generating alarm prompts are shown in the
following table:
Table 8-3 Instrument failure analysis table for alarms
Alarm Alarm
Description Handling suggestions
number source
Press the shortcut key [Ctrl]+[F3] to reset
Sample The sample tray did not move the instrument and try again. If the problem
512
tray to the specified position. persists, please contact the customer service
engineer.
Sample Press the shortcut key [Ctrl]+[F3] to reset
1290 Not down.
arm the instrument.
Reagent&
The reagent&sample probe is
1803 sample Make up the sample size and retest.
not enough, position [{0}].
probe
Unable to receive absorbance
AD
2059 data from the data acquisition Please contact customer service engineer.
module
module.
The interrupt of the data
AD
2060 acquisition module is Please contact customer service engineer.
module
abnormal.
Net water The water barrel is Add enough clean water to the outside of
2304
barrel insufficient. the instrument.
Insufficient water outside the
Net water instrument results in Add enough clean water to the outside of
2305
barrel insufficient water in the clean the instrument.
water tank.
Net water
2306 The water barrel is too full. Suspend the water purifier.
barrel
Send data timeout to LIS
3335 system Please link with the LIS is normal.
serial port.
Alarm Alarm
Description Handling suggestions
number source
The water gap is not up to
Reaction
3584 standard and the cuvette may Clean the cuvette.
tray
have dirt.
Abnormal Check the lamp and retest. If it still alarms,
4097 The bulb energy is abnormal.
lamp please contact the maintenance staff.
Data
collection
Did not receive the maximum
4098 communic It is recommended to check the line.
cup number.
ation is
abnormal
Data
collection
The OD module does not
4099 communic It is recommended to check the line.
adjust the gain.
ation is
abnormal
Instrument Check the sample and reagent balance and
4353 Start test signal timeout.
failure re-run after reset.
Instrument The reaction disk stop signal 1
4354 It is recommended to re-run after reset.
failure times out.
Instrument The cleaning arm action timed
4356 It is recommended to re-run after reset.
failure out.
Instrument
4358 Timer 1 timed out. It is recommended to re-run after reset.
failure
Instrument The reaction disk stop signal 2
4359 It is recommended to re-run after reset.
failure times out.
Instrument The sample arm action timed Check the sample and reagent balance and
4360
failure out. re-run after reset.
Instrument The stirring arm action 2
4362 It is recommended to re-run after reset.
failure times out.
Reagent Reagent bit = {0}, bar code =
200015 Please re-scan after adding item parameters
tray {1}: unknown new reagent!
Reagent bit = {0}, bar code =
Reagent Please confirm the reagent barcode and
200016 {1}: Reagent bar code is
tray rescan
invalid!
Please check the corresponding reagent
data An error occurred while
300000 parameter settings to ensure that the item
processing querying the reference value.
reference values are all set.
An error occurred while
data Please check the corresponding reagent
300001 calculating the test request
processing parameter settings.
result.
Please check if the database service is
data An error occurred while
300002 correct or contact customer service
processing generating the test request.
engineer.
An error occurred while
data Please check the corresponding reagent
300003 calculating the item results for
processing parameter settings.
the sample.
Please check if the database service is
data An error occurred while
300004 correct or contact customer service
processing updating the sample status.
engineer.
Alarm Alarm
Description Handling suggestions
number source
The test result is out of the
valid range. Time = {0},
data Please check the status of the corresponding
300007 sample number = {1}, item
processing sample on the sample tray.
code = {2}, repeat number =
{3}.
Please check the previous fitting parameters
An error occurred while
data and status of this item and ensure that the
300008 auto-scaling the reagent {0}:
processing number of standards is sufficient for the
{1}.
current fit.
data The reagent bottle is empty, Please check the reagent bottles at these
300009
processing position: {0}. locations.
data Please apply for electrolyte calibration
300018 Electrolyte calibration failed
processing again.
The requested barcode {0}
data Please confirm that the LIS return
300020 does not contain any test
processing information is correct.
items
Failed to send data to LIS via
data
300023 database. Sample number = Please check if the LIS link is working.
processing
{0}
The version of the upper
computer and the lower
Communi
computer do not match, the
400022 cation Contact customer service engineer
upper computer version {0},
board
the lower computer version
{1}
data Insufficient sample size for
400070 Add sample
processing {0} location
data
400071 No sample at {0} location Add sample
processing
data
400072 Insufficient reagent volume Add reagent
processing
data
400073 No reagent Add reagent
processing
Sample
Sample driver module
400074 driver Please check the sample driver module
communication is abnormal
module
Reagent
Reagent R1 driver module
400075 R1 drive Please check the reagent R1 drive module
communication error
module
Reaction
Reaction disk module
400076 disk Please check the reaction panel module
communication is abnormal
module
AD AD module communication is
400077 Please check the AD module
module abnormal
400078 Circuit Exhaust is not completed Please check the circuit
Please turn off the PC software first, then
Network connection error,
start the instrument until the network
60001 adapter network card is disabled or
connection is normal, then re-run the PC
not connected
software.
Communi Please close the PC software first, then
60002 cation Communication is abnormal! restart the instrument, and then re-run the
board PC software.
Alarm Alarm
Description Handling suggestions
number source
Communi
The data return length is Please check the communication line or
60003 cation
wrong! communication board.
board
Please check the communication line and
60004 adapter Not online!
re-run the PC software.
Please turn off the PC software, then start
60005 adapter The port number is off! the instrument until the network connection
is normal, and then re-run the PC software.
Please turn off the PC software, then start
The network connection is
60006 adapter the instrument until the network connection
broken!
is normal, and then re-run the PC software.
Communi
The software does not match Please contact customer service engineer to
60010 cation
the instrument number! re-configure the software.
board
When the probe is hit, the
instrument moves abnormally
60011 firing pin Please contact customer service engineer.
and the sample loading has
stopped.
Please check the parameters of the reagent
Reagent Reagent information was not
100000 and confirm that the reagent has been laid
tray found. Reagent code = {0}.
out on the reagent tray.
Test Please check if the communication line is
An error occurred while
100001 applicatio normal and make sure the instrument is in
downloading the test request.
n standby or working normally.
Test An error occurred while the Please check if the communication line is
100002 applicatio instrument was starting to test normal and make sure the instrument is in
n the sample. standby.
An error occurred while Please check the database parameters and
data
100010 loading and refreshing the status and contact customer service
processing
sample tray status. engineers.
Please check the database parameters and
data
100011 Auto review failed. status and contact customer service
processing
engineers.
data Invalid fit type code. Item = Please check the previous fitting parameters
100012
processing {0}. and status of this item.
The reaction tray temperature
Reaction is too low to ensure that the
100013
tray test results are correct and the
test has stopped.
The reaction tray temperature
Reaction is too high to ensure that the
100014
tray test results are correct and the
test has stopped.
The reaction tray temperature
Reaction
100015 is low and the test results may
tray
be affected.
The reaction tray temperature
Reaction
100016 is too high and the test results
tray
may be affected.
The reaction tray temperature
Reaction
100017 sensor is not connected or is
tray
damaged.
Alarm Alarm
Description Handling suggestions
number source
data Please try to reinstall the program or contact
100022 Invalid instrument type.
processing a customer service engineer.
Loading The loading arm is initialized Please reboot or contact customer service
100023
arm incorrectly. engineer.
Reaction Reaction disk moving part Please reboot or contact customer service
100024
tray initialization error engineer.
Mixing Stirring arm initialization Please reboot or contact customer service
100025
arm error engineer.
Unable to get alarm basic Please check if the database service is
100026 other information from database <= correct or contact customer service
AlarmID={0} engineer.
data Verification failed after Please try to reinstall the program or contact
100031
processing initialization a customer service engineer.
Instrument initialization It is recommended to restart the lower
100032 other
failed. computer.
The cup blank value is below
Reaction Please clean the cuvette and replace the
200000 the lower limit and the cuvette
tray cuvette if necessary.
number = {0}.
The cup blank value is above
Reaction Please clean the cuvette and replace the
200001 the upper limit and the cuvette
tray cuvette if necessary.
number = {0}.
Stirring
Abnormal mixing module
400080 drive Please check the mixing module
communication
module
Halogen Please check the halogen lamp, the light path
400082 Low light energy, unable to test
lamp and the cuvette for abnormalities!
Halogen Please contact customer service engineer to
400084 Halogen lamp life limit
lamp replace the halogen lamp
Maintenance-1
Maintenance
Maintenance-2
Maintenance
Maintenance-3
Maintenance
Note: It is not allowed to unplug all the old TPU pipes at one time. Replace them in order to avoid
confusion.
Maintenance-4
Maintenance
Figure9-1Water Filter Assembly’s Disassembly Figure9-2 Pipe connection of pure water float assembly
Maintenance-5
Maintenance
Maintenance-6
Maintenance
3 Dip the gauze in a little pure water or alcohol to wipe the inner wall of the pot.When necessary,
can use gauze dipped in a few neutral cleaning agent to wipe.
4 Use gauze dipped in a few pure water or alcohol to wipe the reagent & sample tray. For the dirt
on the sample position and reagent position, you can use a cotton swab dipped in a few alcohol to
wipe.
5 Wipe the condensate in the reagent & sample pot to the condensate outlet.
Maintenance-7
Maintenance
6 Install the sample &reagent tray into the pot and cover the tray cover .
When the halogen light value is low, and entering the main interface of the software,
click the red alarm button , and the alarm message “The light energy is low, can't
be tested” will be displayed. As shown the figure below. The halogen lamp should be
replaced.
Maintenance-8
Maintenance
Name Quantity
Cross Screwdriver 1 pcs
Medical Rubber Gloves 1 pair
Gauze 1 piece
Warning:
Do not touch the surface of the halogen lamp to avoid affecting the
luminance. If the surface has fingerprints or other stains, can be dipped in
alcohol gauze to wipe.
2 Make sure the analyzer is powered off. After about 30 minutes (complete cooling of the lamp
room) proceed to the next step to avoid burns.
3 Unscrew the screws in face panel and remove it .
Maintenance-9
Maintenance
5 Remove the protective cover on the line bank, unscrew the two fixed terminal posts of the lead
of the halogen lamp with a cross screwdriver, remove the white silica gel lead, and cut the cable
tie with diagonal pliers to replacing the halogen lamp. The operation is shown in the Figure.
Maintenance-10
Maintenance
7 Replace the halogen lamps with new ones according to the reverse steps above, and tighten the
screws. The lead wire should not be loose or warped.
8Turn on the power supply of the instrument. After standby, check that the light spot is 5mm in
diameter. Then, the gain of the unblocking AD reading is conducted at the interface of "instrument
detection", and the test can be conducted only when the value is higher than 48000.
Warning:
The protective cover on the line bank must be installed to prevent short
circuit .
Maintenance-11
Appendix A Product Support Reagents
See the table below
Primary
Sample R1 R2 Sample Decima Min Max Pri-Start Pri-End Sub-Start Sub-End Normal H Sample R1
Item Wavelen Analysis Method Unit Item
Volume Volume Volume Types l Place Abs Abs Point Point Point Point igh Value Volume Volume
gth
ALB 5 300 0 578 One Point End serum 1 g/L 0 3.3 30 30 0 0 55 ALB 5 300
ALP 6 240 60 405 Rate method serum 0 U/L 0 3.3 22 30 0 0 135 ALP 6 240
ALT 22 240 60 340 Rate method serum 1 U/L 0 3.3 23 33 0 0 41 ALT 22 240
AMY 7 250 90 405 Rate method serum 0 U/L 0 3.3 23 33 0 0 104 AMY 7 250
ApoA1 5 225 75 340 Two Point End serum 2 g/L 0 3.3 35 35 12 13 1.9 ApoA1 5 225
ApoB 5 225 75 340 Two Point End serum 2 g/L 0 3.3 35 35 12 13 1.5 ApoB 5 225
ASO 5 240 60 578 Two Point End serum 0 IU/mL 0 3.3 28 29 19 20 166 ASO 5 240
AST 22 240 60 340 Rate method serum 1 U/L -1 3.3 22 33 0 0 40 AST 22 240
Fixed time
BMG 5 225 75 578 serum 1 mg/L 0 3.3 21 28 0 0 1.8 BMG 5 225
method
CHE 5 250 50 405 Rate method serum 0 U/L 0 3.3 22 30 0 0 12600 CHE 5 250
CHO 4 300 0 510 One Point End serum 2 mmol/L 0 3.3 15 15 0 0 5.2 CHO 4 300
CK-MB 15 240 60 340 Rate method serum 1 U/L 0 3.3 22 30 0 0 25 CK-MB 15 240
Fixed time
CREA 15 240 60 510 serum 1 umol/L 0 3.3 22 30 0 0 115 CREA 15 240
method
CRP 20 225 75 340 Two Point End serum 2 mg/dL 0 3.3 35 35 12 13 0.8 CRP 20 225
Appendix-1
Primary
Sample R1 R2 Sample Decima Min Max Pri-Start Pri-End Sub-Start Sub-End Normal H Sample R1
Item Wavelen Analysis Method Unit Item
Volume Volume Volume Types l Place Abs Abs Point Point Point Point igh Value Volume Volume
gth
DBIL 9 240 60 450 Two Point End serum 2 umol/L 0 3.3 35 35 12 13 6.8 DBIL 9 240
GLU 6 300 0 510 One Point End serum 2 mmol/L 0 3.3 34 35 0 0 6.4 GLU 6 300
original
HbA1c 10 225 75 630 Two Point End 2 % 0 3.3 33 33 20 21 5.8 HbA1c 10 225
blood
HCY 24 240 60 340 Rate method serum 1 umol/L 0 3.3 21 29 0 0 15 HCY 24 240
HDL-C 5 225 75 546 Two Point End serum 2 mmol/L 0 3.3 35 35 12 13 2.25 HDL-C 5 225
LDH 6 240 60 340 Rate method serum 0 U/L 0 3.3 22 30 0 0 225 LDH 6 240
LDL-C 5 225 75 546 Two Point End serum 2 mmol/L 0 3.3 35 35 12 13 3.35 LDL-C 5 225
Fixed time
TBA 5 225 75 405 serum 1 umol/L 0 3.3 22 28 0 0 20 TBA 5 225
method
UA 5 240 60 546 Two Point End serum 0 umol/L 0 3.3 35 35 12 13 480 UA 5 240
Fixed time
UREA 5 225 75 340 serum 1 mmol/L 0 3.3 22 30 0 0 8.3 UREA 5 225
method
α-HBD
5 240 60 340 Rate method serum 0 U/L 0 3.3 22 30 0 0 182 α-HBDH 5 240
H
GGT/γ- GGT/γ-G
6 225 75 405 Rate method serum 0 U/L 0 3.3 22 30 0 0 47 6 225
GT T
Appendix-2
Appendix B Cross Contamination Reference Sheet
Project Method
Method principle Method principle
name principle
Enzymatic cycling
TG Oxidase methods → TBA
assay
Enzymatic cycling
TC Oxidase methods → TBA
assay
Substrate
CHE → TG Oxidase method
hydrolysis
Direct method of
LDL-C → GLU(OX) Oxidase method
determination
Direct method of
HDL-C → GLU(OX) Oxidase method
determination
CK IFCC → Mg Methylene Blue
NBT return
FMN → CHE Substrate hydrolysis
method
The above cross-contamination only is taken for example when the BIOBASE reagent is tested on
the BIOBASE series analyzer.
The reagent formula’s changing in cross-contamination, so the above test is only for reference, if
not, please refer to the actual test situation.
Appendix-3
Biobase Biodustry (Shandong)Co., Ltd
Add: NO. 51 South Gongye Road, Jinan, China
Tel: +86-531-81219801/03
E-mail: [email protected]
Web: www.biobase.com/www.meihuatrade.com