DRUG STUDY

cefuroxime
Name of Drug

CLASSIFICATION INDICATION CONTRAINDICATION MECHANISM OF ADVERSE REACTION ROUTE/DOSAGE NURSING

ACTION & SIDE EFFECT INTERVENTION
Therapeutic: ➢ Serious lower ➢ Contraindicated in patients ➢ Inhibits cell-wall CV: phlebitis, ➢ Infusion: 750-mg, ➢ Tell patient to take
Antibiotics respiratory tract hypersensitive to drug or other synthesis, thrombophlebitis. GI: 1.5-g vials, infusion drug as prescribed,
infection, UTI, skin or cephalosporins. even if feeling better.
skin-structure ➢ Use cautiously in patients promoting osmotic diarrhea, pseudomembranous packs, and ADD- ➢ Advise patient who
Pharmacologic: infections, bone or joint hypersensitive to penicillin instability; usually colitis, nausea, anorexia, Vantage vials has difficulty
Second-generation infection, septicemia, because of possibility of cross- bactericidal. vomiting. Hematologic: ➢ Injection: 750 mg, swallowing tablets to
cephalosporins meningitis, and sensitivity with other beta-lactam hemolytic anemia, 1.5 g ask prescriber for the
gonorrhea antibiotics. suspension.
➢ Perioperative ➢ According to the CDC, oral
thrombocytopenia, transient ➢ PO: 125 mg, 250 ➢ Tell parent to shake
Brand name: prophylaxis cephalosporins aren't neutropenia, eosinophilia. mg,u 500 mg suspension well
Zinacef ➢ Mild to moderate acute recommended to treat gonococcal Skin: maculopapular and before measuring
bacterial exacerbations infections. erythematous rashes, dose. Suspension
References: of chronic bronchitis ➢ According to clinical practice urticaria, pain, induration, may be stored at
➢ Acute bacterial guidelines, cefotaxime or room temperature or
maxillary sinusitis ceftriaxone should be used to treat sterile abscesses, temperature refrigerated, but must
➢ Pharyngitis and childhood bacterial meningitis elevation, tissue sloughing at be discarded after 10
tonsillitis and pneumococcal and IM injection site. Other: days.
➢ Otitis media meningococcal meningitis caused anaphylaxis, hypersensitivity ➢ Instruct caregiver to
➢ Uncomplicated skin and by penicillin-resistant strains and give oral suspension
skin-structure infection Haemophilus influenzae type b
reactions, serum sickness. with food.
➢ Uncomplicated UTI meningitis. ➢ Instruct patient to
➢ Uncomplicated ➢ Use cautiously in patients with notify prescriber
gonorrhea history of colitis and in those with about rash, loose
➢ Early Lyme disease renal insufficiency. stools, diarrhea, or
➢ Impe tigo evidence of
superinfection.
➢ Advise patient
receiving drug IV to
report discomfort at
IV insertion site.