Obsos 1
Obsos 1
Obsos 1
postpartum care.3 By encouraging women to engage then independently reviewed potentially eligible full texts
in these self-care interventions, the overall efficiency of based on predetermined eligibility criteria. All stages of
healthcare delivery can be enhanced. In addition, there screening were conducted using Covidence software.18
are interventions for pregnant and postpartum women Any disagreement was resolved by discussion or adjudica-
that are not currently included in WHO’s self-care guide- tion by a third reviewer (JPV).
line, but have the potential of transitioning into a self- The eligibility criteria for inclusion were: (A) Partici-
care paradigm. Examples include prescription medicines pants: women preparing to get pregnant, currently preg-
that can be made available over- the-
counter (OTC), nant, giving birth or in the postpartum period (up to 42
self-collection of samples for testing or home testing kits days after birth), of any age. Studies in which partners
for certain diseases. Some systematic reviews have been or family members carried out self-care for the pregnant
conducted on self- care interventions in pregnancy9–11; woman, were also eligible. Interventions for abortion were
however these previous reviews focused on a few selected not eligible. We also excluded interventions that were
interventions and outcomes, and mainly the antenatal only directed at newborns and postnatal breastfeeding
or postpartum periods. No previous review has explored interventions for improving neonatal outcomes, though
the broad and heterogeneous body of research across antenatal programmes related to preparation for the
preconception, antenatal, intrapartum and postpartum postnatal period were eligible. (B) Interventions: for this
periods, in order to identify those that may be effective review, a self-care intervention was defined as any tool,
or applicable from a self-care perspective. We therefore resource or strategy designed to promote or facilitate self-
aimed to identify all current and emerging self-care inter- care by a woman intending to get pregnant, or a currently
ventions via a scoping review that have been evaluated in pregnant, labouring or in the postpartum period, for the
the context of preconception, antenatal, intrapartum and purpose of improving the quality or coverage of mater-
postpartum care. nity healthcare, and/or improving her health, well-being
and care experiences. To be eligible, interventions must
have been aimed at reducing risks of pregnancy, child-
METHODS birth or postpartum complications and/or enabling a
The scoping review was conducted in accordance with positive pregnancy, childbirth or postpartum experience.
the methodological guide for scoping reviews by Peters Each intervention was evaluated independently by two
and colleagues,12 and reported in accordance with the reviewers for inclusion based on a set of prespecified
Preferred Reporting Items for Systematic Reviews and principles (online supplemental file 4). (C) Compar-
Meta-Analyses guideline for Scoping Reviews13 (online ator: placebo, no treatment or standard care; single-arm
supplemental file 1). The protocol was registered online interventional studies were also eligible. (D) Outcomes:
at https://doi.org/10.17605/OSF.IO/97X25 (online outcomes related to maternal physical, psychological
supplemental file 2). or emotional health, behavioural change affecting a
mother’s own health or diagnostic accuracy of tests for
Electronic searches women. Studies reporting economic outcomes only were
The search strategy was developed in consultation with an not included, and neither were feasibility studies evalu-
information specialist (online supplemental file 3) and ating only retention rates and acceptability. (E) Types
combined self-care concepts with terms related to precon- of studies: randomised trials, quasi-experimental studies
ception, antenatal, intrapartum and postpartum care, and cohort studies, scoping reviews, systematic reviews,
based on the framework proposed by Narasimhan and meta-analyses and overviews of systematic reviews. System-
colleagues.4 The terms and concepts used were informed atic reviews and overviews must have stated some form
by previous reviews of pregnancy care and self-care for of search strategy and presented all included studies in a
other health conditions14–16 and by inputs from team systematic manner to be eligible for inclusion. Ongoing
members with clinical and public health background. studies (defined as trials with protocols published from
The following databases were systematically searched to 2019 onwards which were not completed) were eligible;
identify published studies from inception to 17 October no restriction on date of publication was applied other-
2021: MEDLINE, Embase, EmCare and PsycINFO (via wise. Case series, case studies, case reports, dissertations
Ovid), CENTRAL/Cochrane Database of Systematic and theses, reports published as abstracts only, corre-
Reviews (via Cochrane Library) and CINAHL Plus (via spondence letters, editorials and qualitative studies were
EBSCOhost). The last date of search was 17 October excluded. Only studies with full texts written in English
2021. Reference lists of included studies were manually were eligible.
screened to identify other relevant studies. Grey literature
was not searched after considering the volume and vari- Data collection and analysis
able quality of such evidence.17 Two reviewers independently extracted data using a stan-
dardised extraction form we developed to suit the review
Study selection (online supplemental file 5). Data extracted included
Two reviewers (P-YN and CC) first independently screened characteristics of each study’s population, interventions
all titles and abstracts to exclude irrelevant studies, and and outcomes measured. Study designs were classified as
self-care activities (online supplemental file 9). The WHO categories were interventions for improving
remaining 545 studies (94%), which featured up to three capacity and promoting autonomy in self-care (n=325,
self-care activities, constituted the final sample for identi- 56%), self- care prevention including risk avoidance
fication of self-care interventions. A total of 112 unique and support for physical and mental health and well-
self-care interventions were identified and organised into being (n=296, 51%) and self-care for short-term health
11 broad categories (figure 3; online supplemental file conditions (n=189, 33%). Some WHO categories did
10). The most common self- care categories identified not feature among included studies, such as on-demand
included diet and nutrition (n=143/545, 26%), phys- information services for health information, diagnostic
ical activity (n=132, 24%), psychosocial strategies (n=97, devices in community locations, online symptom checkers
18%) and lifestyle adjustments (n=90, 17%). Few studies for diagnosis and interventions enabling individuals to
featured self-care interventions under the categories of identify location of health facilities/structures. Notably,
sexual health and family planning (2%), self-management we identified no studies that targeted self-care outside
of medication (3%) and self-testing/sampling (3%). All the context of a specific health issue, such as campaigns
identified interventions demonstrate various degrees to promote awareness about self-care or programmes to
of interaction with the health system,4 from little to no improve health and digital literacy.
direct contact (self-awareness/regulation), some interac- Among 545 studies under analysis, self-care was acces-
tion (self-management of health conditions) and close sible through several avenues as described in the WHO
linkage with the health system for follow-up (self-testing classification framework.20 These avenues include health
and diagnosis) (figure 3). facilities (n=238/545, 44%), digital platforms (n=97,
The identified interventions correspond to a range of 18%), community and non-facility venues (n=74, 14%),
categories from WHO’s classification of self-care interven- partner or peer support (n=37, 7%) or OTC products,
tions (online supplemental file 11). The most common for example, nutritional supplements, topical products or
Figure 3 All self-care interventions identified from included studies and their interactions with the health system. HPV, human
papillomavirus; IPTp, intermittent preventive treatment of pregnancy; PPH, postpartum haemorrhage; STD/STI, sexually
transmitted diseases/infections; PrEP, pre-exposure prophylaxis; URTI, upper respiratory tract infection; UTI, urinary tract
infection
support devices (n=69, 13%). In 80 studies (15%), there planning (67% of studies in this category), psychosocial
was insufficient detail to determine that the aforemen- strategies (45%) or physical activity (44%) (figure 4B,
tioned modes of access were used. No studies were iden- online supplemental file 8). Few studies mentioned
tified where the intervention took place at the workplace, involvement of trained community health workers (n=41,
in schools or in emergency or humanitarian settings. 8%), non-trained community members (n=25, 5%) or
Across the self-care categories, provision of informa- family members (n=3, 1%).
tion and demonstration of self-care were most commonly
done in health facilities, especially for self-testing (94% Types of outcomes in self-care studies
of studies in this category) and self-monitoring (58%). Included studies used a diverse range of outcomes,
Provision of similar services outside health facilities, such including both maternal and neonatal outcomes (online
as via community health workers or at community-based supplemental table 1). The most commonly measured
venues, was mainly for the support of self-management ones were neonatal outcomes (birth weight, Apgar
of medication (41%) and physical activity (28%). Home- scores, preterm birth, admission to neonatal intensive
based self-care (ie, direct access to self-
care resources care unit and other neonatal complications) (n=177,
and information at home) was less frequent, mainly in 31%); maternal mental well- being and quality of life
the categories of breast or nipple care (23%) and lifestyle (n=150, 26%), and labour outcomes (duration of labour
adjustments (20%). Digital platforms were popular in stages, labour pain, mode of delivery or labour induc-
some categories, notably self-monitoring (51%). Use of tion methods) (n=125, 22%). A total of 147 studies
OTC products was common in complementary/alterna- (25%) measured behavioural outcomes, mainly related
tive therapies (39%) and breast and nipple care (27%). to reductions in risky behaviours such as smoking or
Lastly, peer or partner support was relatively less common alcohol consumption. Maternal mortality (n=20, 3%)
across categories (7%), and we observed that partner and perinatal mortality (n=67, 12%) were less commonly
support (1%) was relatively less frequent than support evaluated.
from peers (eg, other women, members of support
groups) (6%) (figure 4A, online supplemental file 8).
A large number of studies described the involvement
of health workers in promoting or facilitating self-care
(n=208/545, 38%), especially for sexual health and family
their representation in the sample and disregard poten- primary studies, or where available primary studies were
tial synergy between the self-care components. Besides, not designed to fully deliver the intervention in a self-care
because these studies did not introduce any new self-care approach. For these interventions, well-designed primary
intervention, or a substantive number of studies for any studies that compare a self- care approach with stan-
single self-care intervention that we had already identi- dard care are needed. Examples include self-testing for
fied, it is unlikely that including them into the main anal- proteinuria, or self-measurement of vaginal pH to detect
ysis would change our results and conclusion. Although early signs of bacterial vaginosis. Some self- care inter-
the number of such studies is small (n=35, 6%), they ventions may be particularly useful in limited-resource
represent how self-care can be implemented in real-life, settings, and thus should be evaluated in such settings.
and future reviews should study their effects using appro-
priate methods, for example, component network meta-
analysis.41 42 CONCLUSION
Some limitations must nonetheless be acknowledged. Self-
care interventions during preconception, ante-
We did not formally screen those primary studies partum, intrapartum and postpartum periods are diverse
reported within an included evidence synthesis, and we in scope and implementation characteristics. Many self-
assessed intervention and outcomes characteristics based care interventions were implemented with support from
on the review’s summary description of the included the health system at initial stages of use and uptake. Some
studies. It is possible that the number of primary studies promising self-care interventions require further primary
was there underestimated, or the characteristics of indi- research, though several are more matured and up-to-
vidual primary studies might differ. Our assessment date evidence syntheses are needed. Research on self-care
found 45 primary studies (8% of all included reports) in the preconception period is lacking. Future research
that were also included within an evidence synthesis should explore task-sharing from clinical care to home
included in this review. Given their small number, we or community settings, or effective self-management of
consider it unlikely that these overlapping studies would complications where access to care is unavailable.
substantively affect the overall results. Hence, the distri-
Twitter Phi-Yen Nguyen @PhiYenNguyen3, Özge Tunçalp @otuncalp and Joshua P
bution of study designs (figure 2A, online supplemental Vogel @josh_vogel
file 8) should be considered in addition to the volume
Acknowledgements We thank Steve McDonald (Cochrane Australia) for his
of evidence available for each intervention. We opted guidance in formulating the search strategy.
to focus on maternity- related self-
care, thus excluding Contributors The corresponding author attests that all listed authors meet
interventions that took place after 42 days post partum, authorship criteria and that no others meeting the criteria have been omitted.
or those that related primarily to care of newborns and P-YN and JPV conceptualised the study, wrote the protocol and statistical plan
breast feeding. Our research objectives also mean that we and organised collaborative meetings. P-YN and CC screened the literature and
extracted the data. P-YN analysed the data, wrote the original draft and revised the
did not include qualitative studies. These exclusions do paper. MJP advised on the design of the study. CC, AW, KB, MJP, AMG, MN, MB, OT
not discount their importance, but rather acknowledge and JPV participated in technical and clinical discussions, and reviewed and revised
that these topics require separate, dedicated reviews. Our the paper. JPV is the guarantor of the study.
search of published reports means that self-care inter- Funding This project was funded by UNDP/UNFPA/UNICEF/WHO/World Bank
ventions that have only been evaluated in unpublished Special Programme of Research, Development and Research Training in Human
studies or grey literature would not have been identified. Reproduction (HRP), Department of Sexual and Reproductive Health and Research,
WHO (# PO 202724071). This work was also supported, in part, by the Bill &
With 45 reports excluded as not written in English (3.3% Melinda Gates Foundation INV-001304. While members of our authorship team
of all full-text reports), language bias is possible. (MN, MB and OT) are employed by HRP/WHO, the funder organisations had no
role in the design and conduct of the study; collection, management, analysis and
Future research interpretation of the data; preparation, review or approval of the manuscript; and
decision to submit the manuscript for publication.
This review was conducted for the purpose of guiding
Disclaimer The author is a staff member of the World Health Organization. The
further evidence synthesis activities and assisting the
author alone is responsible for the views expressed in this publication and they
WHO with guideline development in this research area. do not necessarily represent the views, decisions or policies of the World Health
This scoping review identified two distinct groups of Organization.
self-
care interventions, which have different pathways Competing interests The authors declared no competing interests.
forward. The first group are those interventions with a Patient and public involvement Patients and/or the public were not involved in
substantial number of primary studies, where no system- the design, or conduct, or reporting, or dissemination plans of this research.
atic review has been conducted or only outdated system- Patient consent for publication Not applicable.
atic reviews exist. For these interventions—such as use of Ethics approval Not applicable.
clean cookstoves to reduce adverse birth outcomes asso-
Provenance and peer review Not commissioned; externally peer reviewed.
ciated with indoor air pollution, self-care interventions
Data availability statement Data are available in a public, open access repository.
to reduce postpartum depression, or self- collection of
Data supporting the findings and conclusion of this study are included in this
vaginal samples to test for sexually transmitted diseases— published article and its supplementary files. The underlying data set and analytical
up-to-
date systematic reviews are warranted to inform code are available at osf.io/26f7y.
guidelines, clinical practice and self-care programmes. Supplemental material This content has been supplied by the author(s). It has
The second group are interventions with limited or no not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been
peer-reviewed. Any opinions or recommendations discussed are solely those 18 Veritas Health Innovation. Covidence systematic review software,
of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and Melbourne Australia. 2020. Available: www.covidence.org [Accessed
responsibility arising from any reliance placed on the content. Where the content 22 Jul 2021].
includes any translated material, BMJ does not warrant the accuracy and reliability 19 World Bank. The world by income and region. 2021. Available:
https://datatopics.worldbank.org/world-development-indicators/the-
of the translations (including but not limited to local regulations, clinical guidelines, world-by-income-and-region.html [Accessed 20 Jan 2022].
terminology, drug names and drug dosages), and is not responsible for any error 20 Braun V, Clarke V. Thematic analysis. 2012.
and/or omissions arising from translation and adaptation or otherwise. 21 World Health Organization. Classification of self-care interventions
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interventions Geneva. 2021. Available: https://www.who.int/
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